Studies on Skin Blackening Disorder in Harvested Fruits of Japanese Pear ‘Shinsetsu’ (Pyrus pyrifolia Nak.var. Shinsetsu) Grown in Taiwan

Chun-Teh Kuo,Jinn-Chin Yiu 한국원예학회 2006 한국원예학회 기타간행물 Vol.- No.-

A High-Efficiency High Step-Up Interleaved Converter with a Voltage Multiplier for Electric Vehicle Power Management Applications

Kuo-Ching Tseng,Chun-Tse Chen,Chun-An Cheng 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.2

This paper proposes a novel high-efficiency high-step-up interleaved converter with a voltage multiplier, which is suitable for electric vehicle power management applications. The proposed interleaved converter is capable of achieving high step-up conversion by employing a voltage-multiplier circuit. The proposed converter lowers the input-current ripple, which can extend the input source"s lifetime, and reduces the voltage stress on the main switches. Hence, large voltage spikes across the main switches are alleviated and the efficiency is improved. Finally, a prototype circuit with an input voltage of 24 V, an output voltage of 380 V, and an output rated power of 1 kW is implemented and tested to demonstrate the functionality of the proposed converter. Moreover, satisfying experimental results are obtained and discussed in this paper. The measured full-load efficiency is 95.2%, and the highest measured efficiency of the proposed converter is 96.3%.

Will Taiwan`s Economy be Marginalized by China? A Macroeconomic Policy Coordination Approach

Kuo Chun Yeh 연세대학교 동서문제연구원 2009 Global economic review Vol.38 No.1

In Taiwan, economic marginalization has become a major concern that has resulted from the fast growing Chinese economy, imbalanced cross-strait economic and political relations, and a failure to participate in important international trade and financial organizations. Is a China-Taiwan policy cooperative mechanism the best choice for Taiwan`s economic welfare? This paper is to measure Taiwan`s economic marginalization by an international policy coordination approach instead of the conventional free trade agreements. We simulate macroeconomic adjustments of Taiwan and its main economic partners (China and the U.S.) according to the different institutional scenarios and economic shocks. The baseline simulation and sensitivity analyses imply that at the current stage policy coordination between China and Taiwan cannot come into effect without the U.S.`s participation.

슬라이딩 모드를 이용한 대규모 계통의 제어

천희영(Chun Hee Young),박귀태(Park Gwi Tae),곽군평(Kuo Chun Ping),김동식(Kim Dong Sik),임형용(Im Hyeong Yong) 대한전기학회 1987 대한전기학회 학술대회 논문집 Vol.1987 No.7

A High-Efficiency High Step-Up Interleaved Converter with a Voltage Multiplier for Electric Vehicle Power Management Applications

Tseng, Kuo-Ching,Chen, Chun-Tse,Cheng, Chun-An The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.2

This paper proposes a novel high-efficiency high-step-up interleaved converter with a voltage multiplier, which is suitable for electric vehicle power management applications. The proposed interleaved converter is capable of achieving high step-up conversion by employing a voltage-multiplier circuit. The proposed converter lowers the input-current ripple, which can extend the input source's lifetime, and reduces the voltage stress on the main switches. Hence, large voltage spikes across the main switches are alleviated and the efficiency is improved. Finally, a prototype circuit with an input voltage of 24 V, an output voltage of 380 V, and an output rated power of 1 kW is implemented and tested to demonstrate the functionality of the proposed converter. Moreover, satisfying experimental results are obtained and discussed in this paper. The measured full-load efficiency is 95.2%, and the highest measured efficiency of the proposed converter is 96.3%.

Current Trends and Recent Advances in Diagnosis, Therapy, and Prevention of Hepatocellular Carcinoma

Wang, Chun-Hsiang,Wey, Keh-Cherng,Mo, Lein-Ray,Chang, Kuo-Kwan,Lin, Ruey-Chang,Kuo, Jen-Juan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

Hepatocellular carcinoma (HCC) has been one of the most fatal malignant tumors worldwide and its associated morbidity and mortality remain of significant concern. Based on in-depth reviews of serological diagnosis of HCC, in addition to AFP, there are other biomarkers: Lens culinaris agglutinin-reactive AFP (AFP-L3), descarboxyprothrombin (DCP), tyrosine kinase with Ig and eprdermal growth factor (EGF) homology domains 2 (TIE2)-espressing monocytes (TEMs), glypican-3 (GPC3), Golgi protein 73 (GP73), interleukin-6 (IL-6), and squamous cell carcinoma antigen (SCCA) have been proposed as biomarkers for the early detection of HCC. The diagnosis of HCC is primarily based on noninvasive standard imaging methods, such as ultrasound (US), dynamic multiphasic multidetector-row CT (MDCT) and magnetic resonance imaging (MRI). Some experts advocate gadolinium diethyl-enetriamine pentaacetic acid (Gd-EOB-DTPA) MRI and contrast-enhanced US as the promising imaging madalities of choice. With regard to recent advancements in tissue markers, many cuting-edge technologies using genome-wide DNA microarrays, qRT-PCR, and proteomic and inmunostaining studies have been implemented in an attempt to identify markers for early diagnosis of HCC. Only less than half of HCC patients at initial diagnosis are at an early stage treatable with curative options: local ablation, surgical resection, or liver transplant. Transarterial chemoembolization (TACE) is considered the standard of care with palliation for intermediate stage HCC. Recent innovative procedures using drug-eluting-beads and radioembolization using Yttrium-90 may exhibit beneficial effects in HCC treatment. During the past few years, several molecular targeted agents have been evaluated in clinical trials in advanced HCC. Sorafenib is currently the only approved systemic treatment for HCC. It has been approved for the therapy of asymptomatic HCC patients with well-preserved liver function who are not candidates for potentially curative treatments, such as surgical resection or liver transplantation. In the USA, Europe and particularly Japan, hepatitis C virus (HCV) related HCC accounts for most liver cancer, as compared with Asia-Pacific regions, where hepatitis B virus (HBV) may play a more important role in HCC development. HBV vaccination, while a vaccine is not yet available against HCV, has been recognized as a best primary prevention method for HBV-related HCC, although in patients already infected with HBV or HCV, secondary prevention with antiviral therapy is still a reasonable strategy. In addition to HBV and HCV, attention should be paid to other relevant HCC risk factors, including nonalcoholic fatty liver disease due to obesity and diabetes, heavy alcohol consumption, and prolonged aflatoxin exposure. Interestingly, coffee and vitamin K2 have been proven to provide protective effects against HCC. Regarding tertiary prevention of HCC recurrence after surgical resection, addition of antiviral treatment has proven to be a rational strategy.

Recent Research and A, pp.ication of Earthquake Protection System in Taiwan

Chang Kuo Chun,Tsai Meng Hao 한국지진공학회 1998 한국지진공학회논문집 Vol.2 No.3

Research and a, pp.ication of earthquake protection system in Taiwan have become very active since about ten years ago. Many passive isolators, etc., have been studied extensively. These studies have resulted in a few practical a, pp.ications and proposals of two draft design provisions for seismic isolation design of bridges and buildings. In addition to the pass control, analytical studies on active semi-active control have also been very active and the experimental studies have scheduled in the near future. This paper summarise the progress on recent research and a, pp.ication of earthquake protection systems in Taiwan. The emphases are given to the control systems that have been a, pp.ied in practical a, pp.ications.

Traditional Chinese medicine attenuates hospitalization and mortality risks in diabetic patients with carcinoma in situ in Taiwan

Tsai Li-Jen,Chung Chi-Hsiang,Lin Chien-Jung,Su Sheng-Chiang,Kuo Feng-Chih,Liu Jhih-Syuan,Chen Kuan-Chan,Ho Li-Ju,Kuo Chih-Chun,Chang Chun-Yung,Lin Ming-Hsun,Chu Nain-Feng,Lee Chien-Hsing,Hsieh Chang-H 한국한의학연구원 2022 Integrative Medicine Research Vol.11 No.2

Background: Diabetic patients are at high risk of developing cancer. Traditional Chinese medicine (TCM) has become increasingly popular as an adjuvant treatment for patients with chronic diseases, and some studies have identified its beneficial effect in diabetic patients with cancer. The purpoes of this study was to outline the potential of TCM to attenuate hospitalization and mortality rates in diabetic patients with carcinoma in situ (CIS). Methods: A total of 6,987 diabetic subjects with CIS under TCM therapy were selected from the National Health Insurance Research Database of Taiwan, along with 38,800 of 1:1 sex-, age-, and index year-matched controls without TCM therapy. Cox proportional hazard analysis was conducted to compare hospitalization and mortality rates during an average of 15 years of follow-up. Results: A total of 3,999/1,393 enrolled-subjects (28.62%/9.97%) had hospitalization/mortality, including 1,777/661 in the TCM group (25.43%/9.46%) and 2,222/732 in the control group (31.80%/10.48%). Cox proportional hazard regression analysis showed a lower rate of hospitalization and mortality for subjects in the TCM group (adjusted HR=0.536; 95% CI=0.367–0.780, P<0.001; adjusted HR=0.783; 95% CI=0.574– 0.974, P = 0.022). Kaplan-Meier analysis showed that the cumulative risk of hospitalization and mortality in the case and control groups was significantly different (log rank, P<0.001 and P = 0.011, respectively). Conclusions: Diabetic patients with CIS under TCM therapy were associated with lower hospitalization and mortality rates compared to those without TCM therapy. Thus, TCM application may reduce the burden of national medical resources.

Analytical model of expansion for electric arc furnace oxidizing slag-containing concrete

Chun-Ya Shu,Wen-Ten Kuo,Chuen-Ul Juang 사단법인 한국계산역학회 2016 Computers and Concrete, An International Journal Vol.18 No.5

This study applied autoclave expansion and heat curing to accelerate the hydration of concrete and investigated how these methods affect the expansion rate, crack pattern, aggregate size effect, and expansion of electric arc furnace oxidizing slag (EOS)-containing concrete. An expansion prediction model was simulated to estimate the expansion behavior over a long period and to establish usage guidelines for EOS aggregates. The results showed that the EOS content in concrete should range between 20% and 30% depending on the construction conditions, and that coarse aggregates with a diameter of ≥4.75-mm are not applicable to construction engineering. By comparison, aggregates with a size of 1.18-0.03 mm resulted in higher expansion rates; these aggregates can be used depending on the construction conditions. On Day 21, the prediction model attained a coefficient of determination (R2) of at least 0.9.

Practical Aspects of Botulinum Toxin-A Treatment in Patients With Overactive Bladder Syndrome

Chun-Hou Liao,Hann-Chorng Kuo 대한배뇨장애요실금학회 2015 International Neurourology Journal Vol.19 No.4

Intravesical onabotulinumtoxinA (BoNT-A) injection is an effective treatment for overactive bladder syndrome (OAB) that is refractory to antimuscarinics. An injectable dose of 100 U has been suggested to achieve the optimal balance of benefit and safety in patients with OAB. BoNT-A (total volume of 10 mL) was administered as evenly distributed intradetrusor injections (5 U) across 20 sites approximately 1 cm apart (0.5 mL per site) using a flexible or rigid cystoscope. Treatment with BoNT-A was generally well tolerated by most patients, and most treatment-related adverse events were localized to the urinary tract. The prevalence of OAB increases with age, and elderly patients are more vulnerable to complications. The short-term efficacy of intravesical BoNT-A injection for refractory OAB with no treatment-related complications in the elderly population has been documented. Frail elderly patients can experience the same treatment results, such as significantly improved urgent urinary incontinence and quality of life, as young and nonfrail elderly patients with 100-U BoNT-A injections. However, increased risk of larger postvoid residual (PVR) urine and lower long-term success rates were noted in frail elderly patients; around 11% had acute urinary retention, while 60% had PVR urine volume >150 mL after treatment. In addition, intravesical injection of BoNT-A effectively decreased urgency symptoms in elderly patients with OAB and central nervous system lesions. The adverse effects were acceptable, while the long-term effects were comparable to those in patients with OAB without central nervous system lesions. Nonetheless, the possibility of longstanding urinary retention and chronic catheterization in this vulnerable population requires careful evaluation before treatment with intravesical BoNT-A. In conclusion, the current findings indicate that intravesical BoNT-A is an effective and safe treatment for OAB in elderly patients.