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고압, 높은 유속 조건에서의 균일 가열 수직 원형관의 임계열유속 예측 상관식
심재우,김근종 한국공업화학회 2004 응용화학 Vol.8 No.2
새로운 상관식은 물을 유체로 사용하는 균일 가열 수직 원형관에서의 고압, 높은 유속조건 임계열유속을 예측하기 위해 개발되었다. 이 상관식은 기 발표한 임계열유속 데이터베이스(DKU-PDL)를 사용하여 개발되었다. 상관식 개발에 사용된 데이터의 범위는 다음과 같다. 관 내경(D) : 1.95 ~ 44.6㎜, 관 길이(L) : 0.03~4.96M, 압력(P) : 70 ~206bar, 질량유속(G) : 28.07 ~ 10565.03 kg/㎡s, 임계열유속값(CHF) : 0.135 ~ 9.937MW/㎡, 출구 건도(Xe) : -0.88 ~ 1.22. 상관식 개발에 사용된 데이터는 열평형 방법을 사용하여 데이터의 신뢰도를 검증하여 사용하였다
Three Cases of Reversible Agranulocytosis after Treatment with Lamotrigine
Yong Min Ahn,Kunjong Kim,Yong Sik Kim 대한신경정신의학회 2008 PSYCHIATRY INVESTIGATION Vol.5 No.2
Several psychotropic drugs, including clozapine, are known to cause agranulocytosis and this may lead to a fatal condition. Lamotrigine is an anticonvulsant that the Food and Drug Administration (FDA) has approved for the depression of bipolar disorder. A few cases of lamotrigine-induced agranulocytosis have been previously reported on, but the pathophysiology and clinical manifestations are not yet known. This case series reports on 3 patients with different medical conditions who experienced agranulocytosis during treatment with lamotrigine. In these cases, the agranulocytosis occurred a few weeks after initiation of lamotrigine and it rapidly disappeared after discontinuation. We also discuss several characteristics of lamotrigine-induced agranulocytosis. Several psychotropic drugs, including clozapine, are known to cause agranulocytosis and this may lead to a fatal condition. Lamotrigine is an anticonvulsant that the Food and Drug Administration (FDA) has approved for the depression of bipolar disorder. A few cases of lamotrigine-induced agranulocytosis have been previously reported on, but the pathophysiology and clinical manifestations are not yet known. This case series reports on 3 patients with different medical conditions who experienced agranulocytosis during treatment with lamotrigine. In these cases, the agranulocytosis occurred a few weeks after initiation of lamotrigine and it rapidly disappeared after discontinuation. We also discuss several characteristics of lamotrigine-induced agranulocytosis.