Clinical Usefulness of Korean Red Ginseng in Postmenopausal Women with Severe Climacteric Disturbance

Yoshihiro Kikuchi(Yoshihiro Kikuchi),Takehiko Tode(Takehiko Tode),Junko Hirata(Junko Hirata),Hideyuki Nakata(Hideyuki Nakata),Tsunekazu Kita(Tsunekazu Kita) 고려인삼학회 2003 Journal of Ginseng Research Vol.27 No.3

The aim of this study is to evaluate clinical usefulness of Korean red ginseng (RG) on various postmenopausal syndromes. Total plasminogen inhibitor-1 (tPAI-1) in peripheral blood from 9 postmenopausal women with climacteric syndromes (CS) was measured before and 3 months after treatment with daily oral administrat i on of 6g RG and that from 8 postmenopausal women without any CS was also measured as healthy controls. Blood samples were collected in the early morning on the bed-rest. Psychological conditions of postmenopausal women with CS were measured before and 3 months after treatment with RG using simplified menopausal index (SMI). In addition, OKETSU (blood stagnation) syndrome scores and KI deficiency (generalized energy stagnation) scores proposed by Terasawa et al., were recorded before and 3months after treatment with RG in postmenopausal women with CS and in healthy postmenopausal women. OKETSU syndrome scores and tPAI-1 levels in postmenopausal patients with CS were significantly (P<0.001 and<br/> P<0.01) higher than those in healthy postmenopausal women without CS. Similarly, SMI scores and KI deficiency scores in postmenopausal patients with CS were about three-fold higher than those without any CS. When RG was administered for 3 months, KI deficiency scores and OKETSU scores as well as SMI scores declined around the levels of healthy postmenopausal women. Although tPAI-1 levels significantly (P<0.05) decreased after treatment with RG, those did not reach the levels of healthy postmenopausal women. Clinical usefulness of administration of RG to postmenopausal women with CS was confirmed from evaluation not only by modern medicine but also by traditional KAMPO medicine.

Goniotrichopsis reniformis (Kajimura) Kikuchi comb. nov. (Stylonematales, Rhodophyta) from Japan

신종암,Kikuchi, Norio,West, John A.,Kajimura, Mitsuo,Shin, Jong-Ahm 한국조류학회(藻類) 2006 ALGAE Vol.21 No.2

The morphology and life history of Stylonema reniforme Kajimura (Stylonematales, Rhodophyta) from Japan were investigated and its taxonomic placement was discussed. This species has 6-30 discoid chloroplasts devoid of a pyrenoid in each cell. This is a typical feature of the genus Goniotrichopsis. The species reproduced only by monospores, which were formed by the direct transformation of the vegetative cells similar to the type species Goniotrichopsis sublittoralis Smith. Goniotrichopsis reniformis (Kajimura) Kikuchi comb. nov. was proposed. The asexual life history of the present species was completed in 3-10 weeks at 15-20°C in culture.

Measurement of the Permeability in a Ferrite Core by Superimposing Bias Current

Kikuchi, Kousuke,Kanie, Tomohiko,Takeo, Takashi The Korean Institute of Electrical Engineers 2014 The Journal of International Council on Electrical Vol.4 No.1

In this study, we investigate measurement of the magnetic permeability in a ferrite core at RF frequencies when bias current is superimposed on an RF signal with a view to adaptively controlling performance of RF transformers using ferrite cores. A measurement arrangement used comprises a short microstrip line (MSL) circuit including a coaxial conductor (CC) structure consisting of an electrically grounded metal pipe, a center conductor and a sample between them. A bias tee network is incorporated into this MSL-CC circuit in order to superimpose direct current on an RF signal. Using this arrangement, a dependence of permeability on an amplitude of superimposed bias current was measured at frequencies of 10 MHz to 500 MHz. Reliability of the measurement results is discussed based on several experimental data, implying that the method has an accuracy less than 10 % at most of the above frequencies.

Recent trends of healthcare information and communication technologies in pediatrics: a systematic review

Kikuchi Toru,Lee Keehyuck,Hwang Hee 대한소아청소년과학회 2022 Clinical and Experimental Pediatrics (CEP) Vol.65 No.6

As information communication technology (ICT) has advanced, the healthcare industry has embraced it to reduce medical costs, improve health outcomes, and increase patient satisfaction. Healthcare ICT revolutionizes pediatric healthcare. This study aimed to categorize and synthesize findings from the literature regarding the application of ICT in pediatric patients. This systematic review is based on a comprehensive search of Embase, MEDLINE, and Google Scholar. Study selection and coding were performed independently by 2 researchers, followed by narrative categorization. To reflect current trends in ICT for pediatrics, we adopted the Hype cycle technology classification developed by the advisory and information technology firm, Gartner, and the classification of digital health interventions by the World Health Organization. This study included a total of 135 studies. The analysis revealed 7 main types of ICT for pediatrics: (1) telehealth (39 papers), (2) precision medicine (2 papers), (3) automated decision support systems (17 papers), (4) electronic health records (7 papers), (5) patient portals (7 papers), (6) artificial intelligence (AI) (39 papers), and (7) mobile and wearable technologies (20 papers). In particular, we consistently found references to ICT for pediatrics as well as changing and improving healthcare for children. Further studies are required to determine how we can improve ICT productivity for pediatrics, particularly through AI. This study’s results will help healthcare delivery organizations and technology companies consider the future direction of pediatric healthcare.

Future landscape visualization using a city digital twin: integration of augmented reality and drones with implementation of 3D model-based occlusion handling

Kikuchi Naoki,Fukuda Tomohiro,Yabuki Nobuyoshi 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.2

The integration of augmented reality and drones allows past and future landscapes to be visualized from an aerial perspective. However, these visualizations still suffer from the occlusion problem, where the three-dimensional (3D) virtual model displayed in the real world is in front of a real-world object. Currently, city digital twins are essential for the sustainable development of cities and the development of detailed 3D models of cities. By visualizing the city digital twin, augmented reality can facilitate the participation of nonexpert citizens in the decision-making process of urban design, but research examples are limited. Here, using detailed city 3D models, we develop a digital-twin approach to outdoor augmented reality with occlusion handling for both first-person and bird’s-eye views. In a verification experiment, the occlusion handling accuracy of the prototype system was measured to be about 0.8 using intersection over union. The frame rate of the entire prototype system was about 30 fps, and the delay between the controller and the augmented reality device was about 3 s. The internet-based system architecture was developed to integrate augmented reality and drone systems. Our system allows multiple stakeholders involved in building construction projects to observe aerial perspectives of those projects, both on-site and off-site via an internet browser, using augmented reality with occlusion handling.

Carbon Stable Isotope Ratios of Phytoplankton and Benthic Diatoms in Lake Katanuma with Reference to Those of Other Lakes

Kikuchi, Eisuke,Takagi, Shigeto,Shikano, Shuichi,Hideyuki, Doi The Korean Society of Limnology 2005 생태와 환경 Vol.38 No.S

Carbon stable isotope ratios of producers varied in lake ecosystems. In tile present study, we tried to estimate the seasonal variations of carbon isotope ratios of phytoplankton and benthic diatoms in a strongly acidic lake ecosystem. Lake Katanuma is a volcanic, strongly acidic lake (average pH of 2.2), located in Miyagi, Japan. Only two algal species dominate in Lake Katanuma; Pinnularia acidojaponica as a benthic diatom, and Chlamydomonas acidophila as a green alga. Carbon isotope values of P. acidojaponica varied seasonally, while those of particulate organic matter, which were mainly composed of C. acidophila remained fairly stable. The differences suggested that $CO_2$ gas was more frequently limited for P. acidojaponica than C. acidophila, since high density patches of benthic diatoms were sometimes observed on the lake sediment. Generally, carbon concentration mechanisms (CCMs)of microalgae can fix bicarbonate in lakes, and affect the carbon isotope values of microalgae. While, in Lake Katanuma, CCMs of the microalgae may scarcely function because of high $CO_2$ gas concentration and low pH. This is the reason for low seasonal amplitude of carbon isotope values of phytoplankton relative to those in other lakes.

A Damage Model for Void Configuration and Failure under Different Constrained Deformation Regions in Ductile Matrix

Kikuchi, M .,Geni, M . 대한금속재료학회(대한금속학회) 2001 METALS AND MATERIALS International Vol.7 No.4

The constraint effects of SiC particle volume fractions and their specimen geometry are analyzed by conducting tensile tests while changing the SiC particle volume fraction 0%, 2% and 10% and the tensile specimen notch radius 0.5, 1.0, 2.0, 4.0, 8.0 and 16.0 ㎜. The effect of constraint on the void configuration and coalescence are investigated experimentally using 3-dimensional SEM fracture surface observations and 3-dimensional image analysis. It was found that the final void volume fraction and void shape were greatly affected by stress triaxiality and deformation constraint.

Design of Seismic Isolated Tall Building with High Aspect-Ratio

Kikuchi, Takeshi,Takeuchi, Toru,Fujimori, Satoru,Wada, Akira Council on Tall Building and Urban Habitat Korea 2014 International journal of high-rise buildings Vol.3 No.1

When seismic isolation system is applied to high aspect-ratio (height/wide-ratio) steel structures, there are several problems to be taken into consideration. One is lifting up tensile force on the isolation bearing by overturning moment caused by earthquake. Another is securing building stiffness to produce seismic isolation effects. Under these conditions, this paper reports the structural design of high-rise research building in the campus of Tokyo Institute of Technology. With the stepping-up system for the corner bearings, the narrow sides of single span framework are designed to concentrate the dead load as counter-weight for the tensile reaction under earthquake. Also we adopted concrete in-filled steel column and Mega-Bracing system covering four layers on north & south framework to secure the horizontal stiffness of the building.

Two new species of Dentilabus Heinrich (Hymenoptera: Ichneumonidae: Ichneumoninae) from Japan and Korea, with redefinition of the genus

KIKUCHI, NAMIKI,KONISHI, KAZUHIKO Magnolia Press 2018 Zootaxa Vol.4524 No.1

<P>We discovered Dentilabus Heinrich (Icneumoninae: Platylabini) for the first time from the Eastern Palearctic region. Two new species, D. nigripodus sp. n. [Japan and Korea] and D. iyoensis sp. n. [Japan] are described. Dentilabus nigripodus resembles its Western Palearctic congener, D. variegatus (Wesmael), but they can be easily distinguished by the uniformly black hind femora in D. nigripodus. With the inclusion of D. iyoensis, we also redefine the generic limits of Dentilabus. A key to Palearctic species of the genus is provided. </P>

Experimental Study On Seismic Behavior Of Masonry Walls With Column

Kikuchi, Kenji,Park, Kang-Geun 한국공간구조학회 2006 한국공간구조학회지 Vol.6 No.2

본 연구는 보강 조적벽체의 지진거동에 대한 실험적 연구로써, 기둥의 보강, 조적벽체의 보강, 횡하중 높이에 대한 역학적 특성을 분석하였다. 시험체는 구멍이 있는 콘크리트 블록으로 만들었고, 전단 스팬비, 횡하중 높이의 영향, 보강기둥 및 벽체 철근 보강비에 대한 구조적 특성을 파악할 수 있도록 하였다. 벽체의 횡력에 대한 하중점의 벽체 높이의 0.67, 1.08 및 1.1배로 하였다. 수평방향의 철근비는 0, 0.08, 0.18, 수직 방향의 철근비는 0.18, 0.36, 0.64로 하였다. In order to investigate the effect of the height of application point of lateral loads and reinforcing steel bars in walls and columns in improving the seismic behavior of confined concrete block masonry walls, an experimental research program is conducted. A total of twelve one-half scale specimens are tested under repeated lateral loads. Specimens are tested to failure with increasing maximum lateral drifts while a vertical axial load was applied and maintained constant. The specimens adopted are two-dimensional (2D) hollow concrete block masonry walls with different parameters such as shear span ratio, inflection point and percent of reinforcement in confining columns and walls. Test results obtained for each specimen include cracking patterns, load-deflection curve, and strains in reinforcement and walls in critical locations. Analysis of test data showed that above parameters generate a considerable effect on the seismic performance of confined concrete block masonry walls.