유치열에서 Chlorhexidine Varnish와 Polyurethane Sealant의 Streptococcus mutans억제 효과에 대한 연구

이성혁,장기택,김종철 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.1

Numerous chemical agents have been developed to reduce the activity of cariogenic bacteria. Of these, chlorhexidine is acknowledged as the most effective. Gel and mouthrinse have been the traditional method of its application in the mouth. It has been reported that chlorhexidine varnish has prolonged inhibitory effect on the number of streptococcus mutans in saliva and plaque. Recently, chlorhexidine varnish and polyurethane sealant have been developed to promote prolonged anticariogenic effect of chlorhexidine. Products containing 10% chlorhexidine varnish and polyurethane sealant have been developed to prevent caries by reducing the number of streptococcus mutans in the oral cavity. The purpose of this study is to investigate the inhibitory effect of chlorhixidine varnish and polyurethane sealant on streptococcus mutans in the primary dentition. Children with primary dentition containing no active carious lesion were divided into two groups. To the experimental group(n=11), chlorhexidine varnish and polyurethane sealant ( Chlorzoin , Knowell Therapeutic Technologies, Inc. Canada.) was applied once a week for four weeks according to the manufacturer's instruction. Only oral prophylaxis was performed on the control group(n=7). Cariesactivity was measured after using Chlorzoin SM(Knowell Therapeutic Technologies, Inc. Canada.) to incubate streptococcus mutans before and 5, 12, 24 weeks after initial varnish application. The following results were observed.: 1. There was statistically significant decrease in the number of streptococcus mutans in the experimental group for 5 weeks(P<0.01), 12 weeks(P<0.05) after the initial application. but, by 24 weeks significant difference had disappeared. 2. As the inhibitory effect of chlorhexidine varnish and polyurethane sealant application is not everlastion, reapplication at 12-24 weeks should be needed.

인체 지방 및 간장조직 중 유기염소제류 및 PCB의 확인 및 정량기법 체계화 : 2차년도

이상기,양자열,김기욱,이수연,오승민,김대현,정규혁 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

인체 지방 및 간장조직 중 유기염소제류의 확인 및 정량기법 체계화

이상기,양자열,인상환,김기욱,이수연,오승민,김미영,정규혁 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

과민성방광의 비수술적 치료 : 방광의 저장용적을 증가시키는 치료법 Therapy to Increase Bladder Storage Capacity

송윤섭,문기혁,박영호 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Overactive bladder including frequency, nocturia, urgency ate common and Its cause is decreased bladder storage capacity. Non-pharmacologic therapy to facilitate bladder storage capacity are behavioral, bladder overdistention or electrical stimulation. For behavioral therapy, patient education about lower urinary tract function, information about lifestyle changes or dietary modification, bladder training which includes instituting intervals of timed voiding and gradually increasing these intervals, pelvic floor physiotherapy with or without biofeedback are necessary. For physically or mentally challenged individuals, schedulled toileting or prompted voiding is necessary, too. Bladder overdistention, electrical stimulation or neuromodulation are also used for the treatment of overactive bladder.

한국인 모발과 내부장기조직간 Cd, Hg, Pb 및 Zn함량의 상호관련성

유영찬,이상기,양자열,김기욱,이수연,정규혁 한국환경독성학회 2002 환경독성보건학회지 Vol.17 No.1

In order to study the relationships between trace element concentrations of hair and internal organs, autopsy samples of hair, liver, kidney cortex, kidney medulla, heart, lung, spleen, cerebrum, testis and bone from 162 Korean subjects were analyzed for Cd, Hg, Pb and Zn by inductively coupled plasma atomic emission spectrometry. High significant positive correlations were found between the Cd concentration in hair and bone and Pb in hair and lung. Hair Hg levels were highly significantly correlated with organ Hg levels in the liver, kidney cortex, kidney medulla, heart, lung, spleen, cerebrum, testis and bone. And hair Zn levels were highly significantly correlated with organ Zn levels in the kidney cortex, kidney medulla, spleen, testis and bone.

신부전이 동반된 당뇨병 환자에서 발생된 침습성 모균증 : 수술과 Liposomal amphotericin B 및 GM-CSF 병합 요법에 의한 성공적인 치험 1예

이원영,오기원,임국희,장재혁,이동건,최정현,강무일,신완식,차봉연,이광우,손호영,강성구 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.4

저자들은 신부전이 동반된 당뇨병 환자에서 발생된 부비동형 모균증에 대하여 수술과 함께 liposomal amphotericin B 및 GM-CSF의 복합치료를 하여 성공적으로 치료한 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Mucormycosis (zygomycosis) primarily affects diabetic or immunocompromised patients and typically progresses rapidly, necessitating surgical excision and antifungal therapy with amphotericin B. Large doses of amphotericin B are needed for cure, but it has the risk of causing significant renal toxicity. The recent development of liposomal amphotericin B allows antifungal therapy to be administered with potentially improved efficacy and reduced nephrotoxicity. We have experienced a case of paranasal mucormycosis successfully treated with surgery, liposomal amphotericin B and GM-CSF. A 59-year-old male suffering from diabetes mellitus for 6 years was admitted with pain at left maxillary area. He was diagnosed as mucormycosis after cytologic exam on the necrotic nasal mucosa, which showed typical hyphae. He have had diabetic nephropathy with macroproteinuria and had rapidly rising serum creatinine levels with the amphotericin B treatment: creatinine levels reverted to basal level with the use of liposomal amphotericin B. Despite surgical excision and continued antifungal therapy, his infection was not effectively controlled. Therefore, GM-CSF was administered additionally to improve phagocytic activity of leukocytes. He was finally cured after receiving a combination of aggressive surgery, liposomal amphotericin B and GM-CSF. To our knowledge, this is the first detailed clinical description of the treatment of mucormycosis with liposomal amphotericin B in Korea.

실크 생지직물의 정련발염날염에 관한 연구

박건용,박창혁,서기성,김재현,김동철 호서대학교 반도체제조장비국산화연구센터 2001 반도체장비학술심포지움 Vol.2001 No.-

실크 생지직물에 대해 정련날염호로 무늬를 인날하고 증열 처리함으로써 무늬 부분만 정련이 되도록 하는 정련날염 기술을 개발하여 모시 섬유와 같이 뻣뻣하면서 시원한 질감이 나는 정련되지 않은 생직물 부분과 정련에 의해 유연하고 매끄러우면서 광택이 나는 비단 부분이 동시에 한 직물에 공존하면서 입체적인 무늬 표현이 가능한 독특하고 새로운 실크 직물을 개발하였다. 또한 산성염로 등의 합성염료로 염색된 실크 생지직물과 천연염fy로 염색된 실크 생지직물에 대해서 정련날염과 동시에 무늬 부분의 바탕색을 빼내고 착색을 고착시키는 발염의 특수날염 기술을 개발하여 다양한 색상에 의한 무늬 표현이 가능하게 함으로써 고부가가치 실크직물을 생산할 수 있도록 되었다.

음경의 Mondor씨 병 1례

김욱현,문기혁,송윤섭,박영호 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Superficial venous thrombosis of the chest wall was first described by Mondor in 1939. Braun-Falco reported in 1955 superficial penile vein involvement in diffuse thrombophlebitis of the abdominal wall and in 1958 Helm and Hodge first described isolated superficial dorsal penile vein thrombosis. Since then, fewer than 50 cases have been reported. The clinical presentation is usually redness and swelling of the dorsum of the penis, accompanied by a palpable, tender thrombotic vein. This acute and painful disease frightens the patients, who is concerned about his fertility and sexual function. The main cause of this disease is frequent sexual intercourse. Diagnosis is based upon anamnesis, physical examination and penile sonography with color Doppler imaging. It is usually a benign disease which resolves quickly under appropriate medical therapy. We present a man who was visited for this condition and was conservatively treated.

자궁경부암 병기판정 기초검사시 새로운 보조방법으로서 고주파 질식 초음파의 가치

유희석,이은주,장기홍,권혁찬,양정인,김행수,오기석 아주대학교 의과학연구소 1996 아주의학 Vol.1 No.1

To investigate the efficacy of endoluminal ultrasound system (EUS) as a surrogate for high frequency transvaginal ultrasonography and as an optional baseline study in determining parameirial and stromal invasion of early stage cervical cancer, 52 women suspected of cervical cancer underwent EUS. A 12 MHz endoscopic probe was employed to radially scan the cervix for possible lesions suspected to be invasive cancer during a period of 6 months from Feb. 1 to July 1, 1995. Patients also underwent magnetic resonance imaging (MRI) and/or computerized tomography (CT) as a routine mode of baseline study, and were clinically staged by 3 independent physicians specializing in Obstetrics and Gynecology at the Department of Obstetrics and Gynecology, School of Medicine, Ajou University, Suwon, Korea. Thirty one patients subsequently received surgery appropriate for the stage of the disease and the final pathology findings were compared with the results of clinical staging, EUS, MRI/CT by regression analysis. The results showed that there was statistically significant correlation between MRI/CT and pathology (r=0.660, p<0.02), between EUS and pathology (r=0.803, p<0.01), and between clinical staging and pathology (r=0.825, p<0.01). It is concluded that there was significant statistical correlation t>etween EUS, MRI/CT, clinical staging and pathology, but the question remained as to the statistical superiority of EUS over MRI/CT with regard to parametrial invasion and stromal invasion depth assessment. Finally, EUS is useful as an alternative optional diagnostic tool in the baseline study of cervical cancer.

여성 긴장성 요실금에서 Stamey술식의 고찰

김민의,박영호,문기혁 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

The Stamey bladder neck suspension have been performed for female stress incontinence in Soonchunhyang University Hospital from January 1990 to May 1994. This procedure was introduced by Stamey, varying degrees of the success have been reported ranging from 61% to 91% in contemporary series. Someone reported the high recurrence rate with long-term follow-up. Among the 36 patients who received Stamey procedure, 28 patients(78%) receive anterior colporrhaphy for concomitant cystocele simultaneously. The mean follow-up period was 41.4±8.6months, the patient's data were gathered by chart review and the subjective success rate was obtained by questionnaire survey. Urinary retention was the major complication in 8(22.2%),de novo urgency occurred in 4(11%), protracted suprapubic pain occurred in 7(19%), The 20(56%) of the 36 patients were complete dry and 10(28%) were improved. The changes of success rate related to the time of follow-up were; 94.4% immediate after surgery, 88.9% at 6 month, 86.1% at 12 month, 83.3% at 1-5 year. The majority of the failure occurred in the early postoperative period. The 27(90%) of the 30 patients success group received anterior colporrhaphy for concomitant cystocele simultaneously during the Stamey operation. Our success rate was slightly higher than contemporary series, it was suggested that supporting the midurethral segment by anterior colporrhaphy with bladder neck suspension might be the contributing factor for increasing the success rate, but more follow up is warranted.