Political Economy of East Asian Development

Khosla, A . 한국동남아학회 2000 동남아시아연구 Vol.9 No.1

Dielectric behavior of carbon-nanotube-doped ferroelectric liquid crystal mixture

Khosla, Samriti,Sharma, Arti 한국정보디스플레이학회 2013 Journal of information display Vol.14 No.4

The dielectric spectra of pure and 0.1% multi-walled-carbon-nanotube-(MWCNT)-doped ferroelectric liquid crystal (FLC) mixture KCFLC10S materials were studied in the 50 Hz to 1MHz frequency range at different bias voltages. An unusual behavior-increase of ${\varepsilon}^{\prime}$ with increasing E was observed in both samples. It was found that although the relaxation mode was not observable in the MWCNT-FLC sample, the increased effect of the bias voltage on the FLC with the addition of MWCNTs is clearly visible. A theory is presented to explain this effect of MWCNTs in the FLC material.

Impact of Aging on Urinary Natriuretic Peptides in Nocturia and Nocturnal Polyuria

Lakshay Khosla,Joseph U. Boroda,Joshua Salama,Syed N. Rahman,Danielle J. Gordon,Matthew W. Moy,Yonatan Akivis,Alla Akivis,Jason M. Lazar,Jeffrey P. Weiss,Lori A. Birder 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.2

Purpose: The pathophysiology of nocturia and nocturnal polyuria (NP), conditions that become more prevalent with aging, may in part be explained by changes in hormones involved in water homeostasis. The purpose of this study was to analyze the impact of aging on urinary natriuretic peptides in nocturia and NP. Methods: Patients aged ≥18 years completed 24-hour bladder diaries for assessment of nocturia and NP. They were divided into subgroups of ≥65 years old and <65 years old. Urine samples were collected and analyzed for natriuretic peptide (NTproANP, NT-proBNP, and NT-proCNP) levels. Peptide levels were compared between patients with and without nocturia/NP and within age subgroups; correlation to the NP index (NPi) was determined. Results: Compared to patients without nocturia (N=15), patients with nocturia (N=36) had higher median levels of urinary NT-proANP (15.8 pmol/mmol Cr vs. 10.9 pmol/mmol Cr, P=0.016) and NT-proBNP (6.3 pmol/mmol Cr vs. 4.5 pmol/mmol Cr, P=0.021), but showed no differences in NT-proCNP (2.4 pmol/mmol Cr vs. 2.5 pmol/mmol Cr, P=0.967). Patients ≥65 years old with nocturia had higher NT-proANP (29.8 pmol/mmol Cr vs. 11.0 pmol/mmol Cr, P<0.001) and NT-proBNP (9.6 pmol/mmol Cr vs. 5.0 pmol/mmol Cr, P<0.001) than patients <65 years old. Additionally, patients with NP (N=30) showed higher urinary NT-proANP (19.6 pmol/mmol Cr vs. 10.5 pmol/mmol Cr, P<0.001) and NT-proBNP (6.7 pmol/mmol Cr vs. 4.7 pmol/mmol Cr, P=0.020) compared to patients without NP (N=21). NP patients ≥65 years had higher NT-proANP (29.8 pmol/mmol Cr vs. 12.5 pmol/mmol Cr, P<0.001) and NT-proBNP (9.6 pmol/mmol Cr vs. 4.4 pmol/mmol Cr, P=0.004) than patients <65 years old. NPi positively correlated with urinary NT-proANP (RS=0.417, P=0.002) and NT-proBNP (RS=0.303, P=0.031), but not with NT-proCNP (RS=-0.094, P=0.510). Conclusions: Since urinary NT-proANP and NT-proBNP were greater in aged patients with nocturia and NP, natriuretic peptides may contribute to the pathophysiology of these conditions and further research should aim to explore them as targets for management.

Severe Preoperative Disability Is Associated With Greater Mental Health Improvements Following Surgery for Degenerative Spondylolisthesis: A Cohort Matched Analysis

Ishan Khosla,Fatima N. Anwar,Andrea M. Roca,Srinath S. Medakkar,Alexandra C. Loya,Aayush Kaul,Jacob C. Wolf,Vincent P. Federico,Arash J. Sayari,Gregory D. Lopez,Kern Singh 대한척추신경외과학회 2024 Neurospine Vol.21 No.1

Objective: To evaluate preoperative disability’s influence on patient-reported outcomes (PROs) following surgery for degenerative spondylolisthesis (DS). Methods: DS patients who underwent surgical intervention were retrospectively identified from a single-surgeon spine registry. Cohorts based on Oswestry Disability Index (ODI) < 41 (milder disability) and ≥ 41 (severe disability) were created. Demographic differences were accounted for with 1:1 propensity score matching. For the matched sample, perioperative and PRO data were additionally collected. PROs assessed included mental health, physical function, pain, and disability. Pre- and up to 2-year postoperative PROs were utilized. Average time to final follow-up was 15.7 ± 8.8 months. Improvements in PROs and minimal clinically important difference (MCID) rates were calculated. Continuous variables were compared through Student t-test and categorical variables were compared through chi-square tests. Results: Altogether, 214 patients were included with 77 in the milder disability group. The severe disability group had worse postoperative day (POD) 1 pain scores and longer hospital stays (p ≤ 0.038, both). The severe disability group reported worse outcomes pre- and postoperatively (p < 0.011, all), but had greater average improvement in 12-item Short Form health survey mental composite score (SF-12 MCS), 9-Item Patient Health Questionnaire (PHQ-9), visual analogue scale (VAS)-back, and ODI by 6 weeks (p ≤ 0.037, all) and PHQ-9, VAS-back and ODI by final follow-up (p ≤ 0.015, all). The severe disability cohort was more likely to achieve MCID for SF-12 MCS, PHQ-9, and ODI (p ≤ 0.003, all). Conclusion: Patients with greater baseline disability report higher POD 1 pain and discharge later than patients with milder disability. While these patients report inferior physical/mental health before and after surgery, they report greater improvements in mental health and disability postoperatively.

INTRA-REGIONAL TRADE IN AFRICA AND THE IMPACT OF CHINESE INTERVENTION: A GRAVITY MODEL APPROACH

POOJA KHOSLA 중앙대학교 경제연구소 2015 Journal of Economic Development Vol.40 No.4

China’s trade with Africa has increased significantly in the past two decades. The effects of these growing trade volumes (and financial flows) are quite contested. The purpose of this paper is to study the effects of growing Chinese influence in Africa on the intra-regional trade in the continent. This paper estimates a traditional gravity model using Poisson pseudo-maximum-likelihood estimation method for a panel of 135 countries over the period 1990-2012. The results show that African countries are marginalized from world trade. They trade less, compared to a non-African country with similar characteristics. Even though intra-regional trade in Africa is quite low, this paper finds no evidence that these trade volumes are lower than what would be expected (given the characteristics of these countries). However, the results indicate that trade relations with China have distorted patterns of trade in Africa. The analysis shows that Chinese presence has led African countries to import less from (and export less to) other African countries. The massive influx of cheap Chinese goods into African markets combined with preferential tariff treatment offered by the Chinese government to African exporters may explain these patterns. This study also looks at how the effects of Chinese engagement in Africa have changed over time. The results suggest that over the past decade, the effects of China on intra-regional trade have become less negative. Since the late 1990’s, Chinese investment in infrastructure, capacity building combined with high volumes of aid have helped African countries overcome some of the infrastructural bottlenecks and could explain the relatively higher intra-regional trade in the post-2000 period.

Dielectric behavior of carbon-nanotube-doped ferroelectric liquid crystal mixture

Samriti Khosla,Arti Sharma 한국정보디스플레이학회 2013 Journal of information display Vol.14 No.4

The dielectric spectra of pure and 0.1% multi-walled-carbon-nanotube-(MWCNT)-doped ferroelectric liquid crystal (FLC)mixture KCFLC10S materials were studied in the 50 Hz to 1MHz frequency range at different bias voltages. An unusual behavior-increase of ε with increasing E was observed in both samples. It was found that although the relaxation mode was not observable in the MWCNT-FLC sample, the increased effect of the bias voltage on the FLC with the addition of MWCNTs is clearly visible. A theory is presented to explain this effect of MWCNTs in the FLC material.

Prognostic Value in Preoperative Veterans RAND-12 Mental Component Score on Clinical Outcomes for Patients Undergoing Minimally Invasive Lateral Lumbar Interbody Fusion

Ishan Khosla,Fatima N. Anwar,Andrea M. Roca,Srinath S. Medakkar,Alexandra C. Loya,Keith R. MacGregor,Omolabake O. Oyetayo,Eileen Zheng,Aayush Kaul,Jacob C. Wolf,Vincent P. Federico,Gregory D. Lopez,Ar 대한척추신경외과학회 2024 Neurospine Vol.21 No.1

Objective: To evaluate the effect of Veterans RAND 12-item health survey mental composite score (VR-12 MCS) on postoperative patient-reported outcome measures (PROMs) after undergoing lateral lumbar interbody fusion. Methods: Retrospective data from a single-surgeon database created 2 cohorts: patients with VR-12 MCS ≥ 50 or VR-12 MCS < 50. Preoperative, 6-week, and final follow-up (FF)- PROMs including VR-12 MCS/physical composite score (PCS), 12-item Short Form health survey (SF-12) MCS/PCS, Patient-Reported Outcomes Measurement Information System Physical Function (PROMIS-PF), Patient Health Questionnaire-9 (PHQ-9), visual analogue scale (VAS)-back/leg pain (VAS-BP/LP), and Oswestry Disability Index (ODI) were collected. ∆6-week and ∆FF-PROMs were calculated. Minimal clinically important difference (MCID) achievement rates were determined from established cutoffs from the literature. For intercohort comparison, chi-square analysis was used for categorical variables, and Student t-test for continuous variables. Results: Seventy-nine patients were included; 25 were in VR-12 MCS < 50. Mean postoperative follow-up time was 17.12 ± 8.43 months. The VR-12 MCS < 50 cohort had worse VR-12 PCS, SF-12 MCS, PROMIS-PF, PHQ-9, VAS-BP, and ODI scores preoperatively (p ≤ 0.014, all), worse VR-12 MCS/PCS, SF-12 MCS, PROMIS-PF, PHQ-9, and ODI scores at 6-week postoperatively (p ≤ 0.039, all), and worse VR-12 MCS, SF-12 MCS, PROMIS-PF, PHQ-9, VAS-BP, VAS-LP, and ODI scores at FF (p ≤ 0.046, all). The VR-12 MCS < 50 cohort showed greater improvement in VR-12 MCS and SF-12 MCS scores at 6 weeks and FF (p ≤ 0.005, all). The VR-12 MCS < 50 cohort experienced greater MCID achievement for VR-12 MCS, SF-12 MCS, and PHQ-9 (p ≤ 0.006, all). Conclusion: VR-12 MCS < 50 yielded worse mental health, physical function, pain and disability postoperatively, yet reported greater improvements in magnitude and MCID achievement for mental health.

Oxidative Stress Biomarkers in Age-Related Lower Urinary Tract Disorders: A Systematic Review

Lakshay Khosla,Susan Gong,Jeffrey P. Weiss,Lori A. Birder 대한배뇨장애요실금학회 2022 International Neurourology Journal Vol.26 No.1

Purpose: To conduct a systematic review of preclinical and clinical peer-reviewed evidence linking alterations in oxidative stress biomarkers or outcome measures that were also prevalent in specific age-related lower urinary tract (LUT) disorders. Methods: PubMed, Scopus, CINAHL, and Embase were searched for peer-reviewed studies published between January 2000 and March 2021. Animal and human studies that reported on the impact of oxidative stress in age-related LUT disorders through structural or functional changes in the LUT and changes in biomarkers were included. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) protocol was followed. Results: Of 882 articles identified, 21 studies (13 animal; 8 human) met inclusion criteria. Across LUT disorders, common structural changes were increased bladder and prostate weights, ischemic damage, nerve damage and detrusor muscle hypertrophy; common functional changes included decreased bladder contraction, increased bladder sensation and excitability, decreased perfusion, and increased inflammation. The disorders were associated with increased levels of biomarkers of oxidative stress that provided evidence of either molecular damage, protective mechanisms against oxidative stress, neural changes, or inflammation. In all cases, the effect on biomarkers and enzymes was greater in aged groups compared to younger groups. Conclusions: Increased oxidative stress, often associated with mitochondrial dysfunction, plays a significant role in the pathogenesis of age-related LUT disorders and may explain their increasing prevalence. This systematic review identifies potential markers of disease progression and treatment opportunities; further research is warranted to evaluate these markers and the mechanisms by which these changes may lead to age-related LUT disorders.

Cell thickness dependence of liquid crystal parameters

Sood, Nitin,Khosla, Samriti,Singh, Darshan,Bawa, S.S. The Korean Infomation Display Society 2012 Journal of information display Vol.13 No.1

Ferroelectric liquid crystal parameters, spontaneous polarization, and transition temperature were studied as a function of cell thickness. These parameters were found to increase with increasing cell thickness, but an exception was observed for the transition temperature in the case of a thin cell. A simple Landau model is presented to interpret the theoretical and experimental observations. The anomalous behavior is attributed to the electroclinic effect and is explained using the Landau model.

Spectrum Management Models for Cognitive Radios

Kaur, Prabhjot,Khosla, Arun,Uddin, Moin The Korea Institute of Information and Commucation 2013 Journal of communications and networks Vol.15 No.2

This paper presents an analytical framework for dynamic spectrum allocation in cognitive radio networks. We propose a distributed queuing based Markovian model each for single channel and multiple channels access for a contending user. Knowledge about spectrum mobility is one of the most challenging problems in both these setups. To solve this, we consider probabilistic channel availability in case of licensed channel detection for single channel allocation, while variable data rates are considered using channel aggregation technique in the multiple channel access model. These models are designed for a centralized architecture to enable dynamic spectrum allocation and are compared on the basis of access latency and service duration.