하지방사통을 동반한 성인 협부결손성 요추전방전위증의 후방요추간유합술 및 추경나사고정술후 추적결과

최철,김근수,최하영,김철진,김형일,이정청 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

유방의 과립세포종양 1예: 증례보고

민인철, 유근수, 선우영, 윤효영, 송영진 충북대학교 의과대학 충북대학교 의학연구소 2013 忠北醫大學術誌 Vol.23 No.2

유방의 과립세포종양은 슈반세포에서 기원하는 아주 드문 질환이다. 대부분의 환자들은통증을동반 하 지 않는 경성의 유방 멍울을 주소로 내원하게 된다. 따라서 이학적 진찰상 유방암과의 감별이 필요하 다. 유방의 과립세포종양은 임상적으로 유방암과 매우 유사하지만, 98%에서 양성 소견을 보인다. 일 반적인 유방촬영술 및 유방초음파 상에서는 종양 특이적인 소견을 보이지 않으며, 오직 조직생검술을 통한 조직학적, 면연화학적 검사만이 병변을 확진 하는 방법이 된다. 51세 여자 환자가 유방에 만져 지는 멍울을 주소로 외래를 방문하였다. 이학적 검사 상, 좌측 중간외측 유방에 멍울이 만져졌으며, 대흉근 및 주변조직과 고착 되어있는 소견을 보였다. 유방단순촬영 상 좌외측 유방에 비대칭성이 보 였다. 유방 초음파상 1cm크기의 유방 뒤 지방층을 침범하는 종괴가 보였다. 중심 침 조직검사 상 유 방의 과립종양세포 소견을 보였으며, 조직 절제 생검으로 확진 하였다. 임상적으로 유방암과 많이 혼 돈되는 과립세포종양 1예를 보고하고자 한다.

단순 요부 추간판절제술 후 triamcinolone의 창상 도포의 진통 감소 효과

소금영,한형철 朝鮮大學校 附設 醫學硏究所 2003 The Medical Journal of Chosun University Vol.28 No.2

Background: The efficacy of epidural injection of steroids to patients with sciatica is well established. This study was desinged to investigate the efficacy of epidural triamcinolone application as an adjuvant therapy to reduce pain after simple lumbar discectomy. Method: We evaluated the efficacy of wound infiltration with triamcinolone in 36 consecutive patients undergoing elective simple lumbar discectomy in a prospective, double- blind, randomized controlled trial. The pain scores were recorded at 1, 3, 6, 12, 24 hours and total morphine dosage after 24 hours was checked. Results: Total morphine dosage after 24 hours was 8.83, 4.71, 2.75 mg for patients receiving no steroids, triamcinolone 40 mg, and 60 mg. Conclusions: Application with triamcinolone 60 mg is a safe and effective method for providing postoperative pain relief and reducing narcotic use in patient undergoing lumbar laminectomy.

시클로펜틸아렌술포네이트 및 시클로헥실아렌술포네이트와 아닐린과의 친핵성치환반응

吳爀根,趙仁鎬,申哲昊,權永峰 全北大學校 1993 論文集 Vol.35 No.-

The nucleophilic substitution reactions of cyclopentylarenesulfonates and cyclohexylarenesulfonates with anilines in acetonitrile at 65.0℃ are investigated. The cross-interaction constants ρxz(and βxz) between substitue-nts in the nucleophile(X) and leaving group(Z) are positive and have relatively small mmagnitude. The transition state(TS) variation is consistent with that predicted by the More O'Ferrall-Jencks diagram as expected from the positive ρxz. The small magnitude of ρxz correctly refrects a relatively loose TS structure in contrast to the tight TS for primary alkyl derivatives under similar reaction conditions.

자궁경부 상피내병변에서 HPV와 p53 단백의 변화에 대한 면역조직화학적 소견

기근홍,황철기,신향미 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Background and Objectives : p53 is a tumor suppressor gene. Loss of function of the p53 tumor suppressor gene implicated in a wide variety of human tumors. Many mechanisms are involved in p53 dysfunction. One of the mechanisms is binding of oncogenic virus such as human papillomavirus (HPV). HPV infection are strongly linked to the development of cervical neoplasia including cervical intraepithelial neoplasia (CIN) of uterine cervix The purpose of this study is to investigate the relationship between aberrant p53 expression and presence of HPV DNA in CIN of the uterine cervix. Materials and Methods : In the present study, the author analyzed 35 cases of paraffin-embedded CIN, including 10 cases of grade 1, 10 cases of grade Ⅱ, and 15 cases of grade Ⅲ CIN by the immunohistochemistry and in situ hybridization. Results : Overall positive rate of HPV DNA type 16 and type 18 was 74.3% (26 cases) and 65,7% (23 cases), respectively. Nuclear accumulation of p53 was found in 22 cases (62.9%) of all CIN. In negative cases of HPV DNA type 16, the p53 was positive in 18 cases and negative in 8 cases. In positive cases of HPV DNA type 18, the p53 was positive in 16 cases and negative in 7 cases. In negative cases of HPV DNA type 16, the pS5 was positive in 6 cases and negative in 6cases. Conclusion : This results suggest that HPV infection may contribute to the DNA damage associated with the accumulation of aberrant p53 protein, and then closely relate to the progression of cervical neoplasms. But, alteration of p53 Protein levels and presence of HPY DNA was not an exclusive markers of cervical tumorigenesis.

RCGKA를 이용한 최적 퍼지 예측 시스템 설계

방영근,심재선,이철희 江原大學校 産業技術硏究所 2009 産業技術硏究 Vol.29 No.B

In the case of traditional binary encoding technique, it takes long time to converge the optimal solutions and brings about complexity of the systems due to encoding and decoding procedures. However, the ROGAs (real-coded genetic algorithms) do not require these procedures, and the k-means clustering algorithm can avoid global searching space. Thus, this paper proposes a new approach by using their advantages. The proposed method constructs the multiple predictors using the optimal differences that can reveal the patterns better and properties concealed in non- stationary time series where the k-means clustering algorithm is used for data classification to each predictor, then selects the best predictor. After selecting the best predictor, the cluster centers of the predictor are tuned finely via RCGKA in secondary tuning procedure. Therefore, performance of the predictor can be more enhanced. Finally, we verifies the prediction performance of the proposed system via simulating typical time series examples.

교과교육과목에서의 도덕훈련 내용에 관한 고찰

이근철 仁川敎育大學校 1992 論文集 Vol.26 No.1

This study aims to develop an integrated curriculum for moral discipline in primary school. For this, following topic have been dealt with; 1) What becomes the Justification of integration curriculum for moral disciplione. 2) What are the proper methods for the integration curriculum management of moral discipline. 3) Moral discipline strategies in curriculum have been seek for. The resulted are as follows respectively. 1) In view of moral education, morality includes only approximative, cognitive and affective domain, Hence, we become much more sensitive to the motion of the nonformal or hidden curriculum as a factor in moral education. For proper moral discipline, every viewpoint should be gathered and selected to be moral Values in curriculum, For the same reason, in order to have such moral discipline that would become a curriculum integeration. 2) As for the thereby reguired methods of integration curriculum of moral discipline, multi-disciplinary or inter-disciplinary integration methods base on concepts in the value of eduction were pursued and apoproached. 3) For moral discipline strategies, reconstruction and selected values in curriculum. Namely, values in learning language, social studies, mathematics education, art, physical education, home economics teaching. 4) Therefore, moral education ultimately is realized in activities, program that are reasonably accessible, interestion to students, and offer some promise of success. The integrated curriculum management for moral discipline must also deal with the nature of the moral principles proposed; How the values will be used, the relation of the topic of moral education to other subjects in the curriculum.

장거리선수의 폐기능에 대한 연구

金昌根,朴喆斌 韓國體育大學校附屬 體育科學硏究所 1983 韓國體育大學校附屬 體育科學硏究所論文集 Vol.2 No.1

The purposed of the study was to investigate pulmonary function on endurance athletes including marathon runners, cyclists, and swimmers. The results were compared to predicted values which based on physical condition, such as body height and weight etc. The subjects were 11 marathon runners including 2 national Caliber runners, 17 cyclists including 8 national caliber cyclists, and 3 male and female caliber swimmers. The results were summerized as follows: 1). In case of marathon runners,actual values of FVC, RV,TLC,RV/TLC, and D?? , were shown higher than predicted values, invesely actual value of FEV/FVC, MVV, D??/V?? were shown lower than predicted values, and K's C (permeability) was shown significant lower than predicted values(p<0.05). 2). In case of cyclists, actual values of FVC, FEV/FVC, and D?? were shown significantly higher than predicted values (p<0.05), and actual values of RV, TLC, and RV/TLC were much more than predicted values, invesely actual values of MVV, and DL/VA were shown lower than predicted values, and K' sC was shown the same tendency with case of marathon runners(p<0.05). 3). In case of male swimmers, actual values of FVC, RV, TLC, and RV/TLC were shown higher than predicted values especially with FVC was higher than others (p<0.05), and actual values of FEV/FVC, MVV, D??, D??/V??, and K's C were shown lower than predicted values, especially FEV/FVC and K??s C were lower than others (p<0.05). In case of female swimmers, actual values of FVC, RV, RV/TLC, and D?? were shown higher than predicted values, and FVC was shown the same tendency with male swimmers. Actual values of FEV/FVC, VV, D??/V??, and K'sC were lower than predicted values, especially K'sC was lower than others (p<0.05). 4). To be compared with marathon runners and cyclists, cyclists were higher than marathon runner with age and body height, and there were no significant differences among the tested items but in terms of MVV, D??, and V?? were shown that cyclist were higher than marathon runners. 5). To be compared with national caliber and university or college caliber elite athletes, in case of marathon runners, national caliber athletes were shown higher level in eacg tested items except alveolar ventilation (V??) than university of college caliber elite athletes, and in terms of cyclists, national caliber athletes were shown higher level than university or college caliber elite athletes in each tested items except FVC, FEV/FVC, and D??.

인공해수 중에서 0.17C-Ni-Cr-Mo 합금강의 피로수명

이성근,김효종,박철민 東亞大學校 海洋資源硏究所 1990 硏究論文集 Vol.3 No.1

Fatigue life of base and weld metal of 0.17C-Ni-Cr-Mo alloy steel have been investigated in synthetic seawater under smooth and notched conditions at frequencies of 4Hz and 30Hz. Most data for the alloy steel agree with that for HY-100 steel. The form of a simple power relation can be suggested as a conservative design criteria for the fatigue life in aggresive environments.

HCBKA를 이용한 Interval Type-2 퍼지 논리시스템 기반 예측 시스템 설계

방영근,이철희 江原大學校 産業技術硏究所 2010 産業技術硏究 Vol.30 No.A

To improve the performance of the prediction system, the system should reflect well the uncertainty of nonlinear data. Thus, this paper presents multiple prediction systems based on Type-2 fuzzy sets. To construct each prediction system, an Interval Type-2 TSK Fuzzy Logic System and difference data were used, because, in general, it has been known that the Type-2 Fuzzy Logic System can deal with the uncertainty of nonlinear data better than the Type-1 Fuzzy Logic System, and the difference data can provide more steady information than that of original data. Also, to improve each rule base of the fuzzy prediction systems, the HCBKA (Hierarchical Correlation Based K-means clustering Algorithm) was applied because it can consider correlationship and statistical characteristics between data at a time. Subsequently, to alleviate complexity of the proposed prediction system, a system selection method was used. Finally, this paper analyzed and compared the performances between the Type-1 prediction system and the Interval Type-2 prediction system using simulations of three typical time series examples.