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최병제,최형준,이제호,김기덕,박수정 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.3
1. Hypophosphatasia 는 골조직 및 치아조직의 비정상적인 석회화를 나타내는 대사장애로, 특징적구강내 소견 인 우치의 조기탈락 양상으로 치과에서 조기진단이 가능하다. 2. 본 증례에서 상악궁 확장을 동반한 의치 제작으로 심미적, 기능적으로 양호한 결과를 얻었으며, 영구치열기 까지 장기적 관찰 및 치료가 필요할 것으로 사료된다. hypophosphatasia is a rare metabolic disorder which manifests characteristics such as abnormal mineralization of bone and dental tissues, diminished serum and tissue alkline phosphatase, and increased urinary secretion of PEA. It ingerited as an autosomal recessive or dominant trait and occurs in all races. In general, hypophosphatasia can be classified in 4 subtypes which are the perinatal, infantile, childhood, adult type depending upon the age at presentation and severity. In young children with Hypophosphatasia the long bones show irregular defects, and the skull showes poor calcification. In older children with premature closure of the skull sutures there may ve multiple lucent area called gyral or convolutional markings, described as resimbling beaten copper, presumably resulting from increased intracranial pressure,Examination of the jaws reveals a generalized lucency of the maxilla and mandible, the cortical bone and lamina dura are thin, and the alveolar bone may be deficient. Clinical features of Hypophosphatasia imclude premature loss of deciduous teeth, especially incisors, hypoplasia of aplasia of root cementum, enamel hypoplasia, irregular calcification of dentin, large pulp chamber, and resorption of marginal alveolar bone and roots. Our report involves a patient with a chief complaint of early loss of both Mx. and Mn. deciduous ncisors. after conducting a through clinical and radiographic examination this patient was referred to pediatrics under the suspicion of hypophosphatasia, the diagnosis proved to be correct and successful results were accomplished through a denture made to improve esthetics and function.
남궁기,이호영,노재성 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.1
A single stage random cluster sampling was conducted and 1,450 samples were selected from Kangwha Island. A psychiatric epidemiologic survey was done using Korean version of NIMH-Diagnostic Intervies Schedule. Sociodemographic characteristics, natural course, and frequencies of DIS alcoholic symptoms were compared among alcohol dependence, alcohol abuse and non-alcoholic groups. The results were as follows; 1) In comparison of sociodemographic characteristics between alcohol dependence and alcohol abuse group, marital status and age distribution showed significant differences but there were no significant differences in sex and occupation between two groups. 2) There were no significant differences in mean age of first heavy drinking episode and onset of symptoms in alcohol abuse and alcohol dependence group. 3) Mean duration of alcohol use disorder was significantly different between alcohol dependence and alcohol abuse group(13.5±12.2 years and 9.2±10.8 years). And it was also significantly different between male alcohol dependence and male alcohol abuse group(13.1±11.9 years and 9.2±10.7 years). 4) The latency period of alcohol use disorder in alcohol abuse and alcohol dependence group were 7.0±10.3 years and 8.7±10.1 years in each, which was not significantly different and in comparison of latency period in only male, there was no significant difference between two groups(7.3±10.4 years and 9.5±9.4 years). 5) In comparison of frequencies of alcoholic symptoms between alcohol dependence and alcohol abuse group, frequencies of symptoms such as `think oneself as a excessive drinker', `bender at least two days', `continue to drink even with serious physical illness' were significantly higher in alcohol dependence group. 6) In comparison of prevalence of medical complications between alcohol dependence and alcohol abuse group, prevalence of peripheral neuropathy, stomach disease, liver disease and memory impairment were significantly higher in alcohol dependence group.
韓國 노랑초파리의 自然集團에 있어서 P elements의 分布에 관한 硏究
成耆昌,金滿在,金溶聲 성균관대학교 기초과학연구소 1988 論文集 Vol.39 No.2
Isofemale lines of Drosophila melanogaster were established from Moonsan and Osan, Korea and were tested for GD sterility. The results are as follows; 1. Using π_2 (strong P) strain and Canton-S (true M) strain as a standard strains, the frequencies of P cytotype for all isofemale lines were 37.7% (Moonsan) and 56.5%(Osan), but the activities of P factor very low. 2. The distributions of strain types by Kidwell were 62.3%, 43.5% for M' (pseudo-M) strain, and 37.7%, 56.5% for Q (weak P) strain in Moonsan and Osan, respectively. Thus, it was appeared that these populations are consisted of M' and Q strains. 3. The results suggested that the activities of P elements were regulated by their P cytotypes though the potentialities of P activity were present in these populations.
Ethanol 및 Polylysine 첨가가 김치의 저장성에 미치는 효과
정진웅,박기재,정승원 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3
김치 제조시 위생적 품질 개선을 위하여 ethanol과 천연항균물질인 polylysine의 복합 첨가를 검토하였다. Ethanol 농도를 0.3, 0.6 및 0.9%로 첨가하여 김치를 제조한 후 10℃에 저장하면서 3일 간격으로 총균수, 대장균군, 젖산균, 곰팡이 및 효모 등을 비교 측정한 결과, ethanol의 첨가는 대장균군과 젖산균의 생육 억제에 있어 보다 효과적인 것으로 나타났으며, ethanol 농도 0.6% 첨가시부터 미생물 생육 억제 효과가 뚜렷하게 나타났다. 또한 ethanol 0.6%를 첨가하여 담근 김치는 저장중 pH 저하 및 산도 상승에 대한 지연효과를 보여주었고, 저장중 관능특성의 변화에서도 신냄새, 이취, 신맛, 이미, 조직감 및 종합적 기호도의 모든 항목에서 가장 우수한 것으로 평가되었다. Polylysine은 단일 사용시 보다는 0.6% ethanol과 복합 첨가했을 경우 미생물 생육 억제에 상승효과를 보였으나 관능 평가에서 이미 이취를 느낀 것으로 평가되어 0.6% ethanol 단일 첨가가 미생물 증식 억제 및 발효 지연에 가장 효과적인 것으로 나타났다. Addition of ethanol and/or polylysine to kimchi ws investigated to improve its microbial hygienic quality and to extend shelf-life. Ethanol was added to kimchi with several concentrations(0.3%, 0.6%, 0.9%) and stored at 10℃. Addition of 0.6% and 0.9% ethanol showed apparent inhibitory effect on growth of microorganism, but any distinct difference was not found between those concentrations. Addition of ethanol was more effective on growth inhibition of coliform and lactic acid bacteria than other. Addition of 0.6% and 0.9% ethanol retarded apparently pH decrease and acidity increase. Although addition of 0.6% ethanol in combination with 0.12% polylysine showed good retardation of pH decrease and acidity increase, overall organoleptic quality was not good because of off-flavor and taste. Also, addition of 0.6% ethanol showed good overall organoleptic quality.
박영민,송승기,강재필,서용문 명지대학교 자연과학연구소 1995 자연과학논문집 Vol.12 No.-
펄스형 핵사중극 공명장치(Pulsed system)를 이용하여 상온에서 NaNO? 분말시료의 위와 아래 공명진동수, 핵사중극 결합상수, 비대칭인자와 스핀-스핀완화시간을 구하였다. FID공명선으로부터 구한 값은 υ+=4.6354 NHz/ υ-=3.5983 MHz, e?qQ/h=5.4891 MHz와n=0.3779이었다. 90?,ι, 180? 펄스연속(spin-echo 신호)과 r를 변화시켜 얻은 진폭을 이용하여 스핀 -스핀 완화시간 T2를 측정하였다. 이결과 υ(T?)=2.50ms, υ-(T?)=2.17ms임을 보였다. Measurements of the upper and lower resonance freqency, quadrupole coupling constant, asymmetry parameter and spin-spin relaxation time are reported for NaNO? powder sample by using the pulsed NQR system at room temperature.From FID line-shapes, we obtained υ=4.6354 MHz, υ=3.5983 MHz, e?qQ/h=5.4891 MHz and η=0.3779. The spin-spin relaxation time T? was maesured using a 90?,ι, 180? pulsed sequanco (spin-echo signals) and varying τwhile measuring the amplitude of the echo. The result showed υ+(T?) =2.50 ms and υ+(T?) =2.17ms.
Epstein-Barr virus(EBV)와 연관된 Nasal type T/Natural Killer(NK)-cell lymphoma 1예
지두현,최지호,성경제,문기찬,고재경 울산대학교 의과대학 1996 울산의대학술지 Vol.5 No.1
Nasal type T/NK-cell lymphoma는 병리조직학적으로 응고성 괴사가 동반된 혈관중심성 침윤을 특징으로하며 T-cell과 NK-cell 항원을 모두 표현하는 면역조직화학염색 소견을 보이는 매우 드문 피부 림프종으로서 EBV와의 연관성이 흔히 보고되고있다. 저자들은 42세 여자에서 발생한, 전신적인 홍반성 구진, 판, 결절의 임상양상을 보였으며 피부 병변에서의 EBV-encoded RNA(EBER)에 대한 in situ hybridization상 양성소견을 보였고 전산화단층촬영, 골주사, 갈륨주사 등의 검사상 비강, 위장관 및 다른 내부장기 침범소견은 보이지 않아서 피부에만 국한된 경우로 사료되는 nasal type T/NK-cell lymphoma 1예를 보고하는 바이다.
Tufted Angioma와 유사한 소견을 보인 화농성 육아종
장경애,최정철,최지호,성경제,문기찬,고재경 대한피부과학회 1999 대한피부과학회지 Vol.37 No.6
Tufted angiomas are rare slowly progressive vascular lesions found typically in children and young adults, usually involving the trunk and neck. Microscopically, groups of capillary tufts, many uncanalized, were found dispersed at various levels in the dermis. Some authors regarded tufted angioma as a member of lobular capillary hemangiomas. We describe a pyogenic granuloma mimicking acquired tufted angioma on the lip in a 59-year-old woman. We suggest that a term lobular capillary hemangioma$quot; may be preferable in this case.