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      • KCI등재

        Preparation of Copper Sulfide by Microwave Assisted Method and Its Application on Superhydrophobic, Anti-UV and Photocatalytic Cotton Fabric

        Ke-Cheng Yang,Li-Hui Xu,Hong Pan,Li-Ming Wang,Yong Shen,Ying Ding 한국섬유공학회 2020 Fibers and polymers Vol.21 No.6

        In this work, solid spherical and hollow spherical CuS were prepared by microwave assisted method withPEG4000 as dispersant. The CuS was characterized by particle size analysis, scanning electron microscope(SEM), nitrogenadsorption and desorption, and X-ray diffraction (XRD), respectively. The effects of PEG4000, ratio of thiourea: copper, andmicrowave power on particle size of CuS were discussed, and the effects of particle size on photocatalytic property wereevaluated. The solid spherical CuS had average particle size of 189.1 nm and specific surface of 9.54 m2/g. The hollowspherical CuS had average particle size of 502.7 nm and specific surface area of 16.01 m2/g. The results showed the hollowspherical CuS had better photocatalytic property. In addition, the cotton fabric was treated by hollow spherical CuS/polydimethylsiloxane (PDMS) to prepare multifunctional textile in this work. The treated cotton fabric was characterized bySEM. The treated cotton fabric achieved the superhydrophobicity with contact angle of 156.9 o and sliding angle of 8 o, goodphotocatalytic properties for methylene blue, and exceptional UV resistance with UPF of 223.52.

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        Recombinant-attenuated Salmonella Pullorum strain expressing the hemagglutinin-neuraminidase protein of Newcastle disease virus (NDV) protects chickens against NDV and Salmonella Pullorum challenge

        Ke Ding,Ke Shang,Zu-Hua Yu,Chuan Yu,Yan-Yan Jia,Lei He,Cheng-Shui Liao,Jing Li,Chun-Jie Zhang,Yin-Ju Li,Ting-Cai Wu,Xiang-chao Cheng 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.2

        Newcastle disease virus (NDV) and Salmonella Pullorum have significant damaging effects on the poultry industry, but no previous vaccinecan protect poultry effectively. In this study, a recombinant-attenuated S. Pullorum strain secreting the NDV hemagglutinin-neuraminidase(HN) protein, C79-13ΔcrpΔasd (pYA-HN), was constructed by using the suicide plasmid pREasd-mediated bacteria homologousrecombination method to form a new bivalent vaccine candidate against Newcastle disease (ND) and S. Pullorum disease (PD). The effectof this vaccine candidate was compared with those of the NDV LaSota and C79-13ΔcrpΔasd (pYA) strains. The serum hemagglutinationinhibition antibody titers, serum immunoglobulin G (IgG) antibodies, secretory IgA, and stimulation index in lymphocyte proliferation wereincreased significantly more (p < 0.01) in chickens inoculated with C79-13ΔcrpΔasd (pYA-HN) than with C79-13ΔcrpΔasd (pYA) but werenot significantly increased compared with the chickens immunized with the LaSota live vaccine (p > 0.05). Moreover, the novel strain provides60% and 80% protective efficacy against the NDV virulent strain F48E9 and the S. Pullorum virulent strain C79-13. In summary, in this study,a recombinant-attenuated S. Pullorum strain secreting NDV HN protein was constructed. The generation of the S. Pullorum C79-13ΔcrpΔasd(pYA-HN) strain provides a foundation for the development of an effective living-vector double vaccine against ND and PD.

      • KCI등재

        Preparation of CuS/SiO2 Composite Modified Aerogel and Its Superoleophobic and Photocatalytic Properties

        Ke-Cheng Yang,Li-Hui Xu,Hong Pan,Li-Ming Wang,Yong Shen,Ying Ding 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2020 NANO Vol.15 No.03

        In this study, CuS/SiO2 composite modified aerogel was prepared by the incorporation of hollow spherical CuS into methyltrimethoxysilane-based SiO2 sol and modification with hexadeca-fluorodecyltriethoxysilane via acid-base catalyzed sol–gel reaction and drying under ambient pressure. The CuS/SiO2 composite modified aerogel was characterized by Fourier-transform infrared (FT-IR) spectrometry, scanning electron microscope (SEM), nitrogen gas adsorption and desorption and X-ray diffraction (XRD), respectively. The effects of CuS and fluorosilane concentration on density and porosity of aerogel, oleophobic and photocatalytic properties were evaluated. The results showed that structure and physical properties of aerogel had some effect by introducing CuS and fluorosilane, and the CuS/SiO2 composite modified aerogel with density of 0.146 g/cm3 and specific surface area of 241 m2/g achieved super-oleophobicity with oil contact angle of 152.8fl and sliding angle of 10fl, and good photocatalytic properties for methylene blue.

      • Factors Potentially Associated with Chemotherapy-induced Anemia in Patients with Solid Cancers

        Cheng, Ke,Zhao, Feng,Gao, Feng,Dong, Hang,Men, Hai-Tao,Chen, Ye,Li, Long-Hao,Ge, Jun,Tang, Jie,Ding, Jing,Chen, Xin,Du, Yang,Luo, Wu-Xia,Liu, Ji-Yan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10

        Purpose: Chemotherapy-induced anemia (CIA) is one of the most important causes of anemia in cancer patients. This study was conducted to describe the prevalence and characteristics of CIA in solid cancer patients in the Chinese population, and to explore the relationship of white blood cell (WBC) or platelet decrease with CIA. Methods: Data on age, gender, tumor diagnosis, anti-cancer treatment and blood cell analyses were available from 220 untreated non-anemic cancer patients who received at least 2 cycles of chemotherapy, and the data were analyzed to assess their relationship with CIA or its severity. Results: 139 patients (63.2%) presented anemia, most being Grade 1 or 2. Esophageal and lung cancers were associated with a high prevalence. G3/4 leucopenia and decrease of platelets were identified as independent risk factors for the occurrence of CIA. Moreover, G3/4 leucopenia, decrease of platelet and G3/4 thrombocytopenia were found to be also associated with the severity of CIA. Cisplatin-containing regimens were a main potential factor in causing CIA, although significant association was only found on univariate analysis. Conclusion: Anemia or decrease in hematoglobin are common in Chinese cancer patients receiving chemotherapy. Cisplatin-containing regimens might be an important factor influencing the occurrence of CIA. Our analysis firstly described some risk factors, such as decrease of platelets or WBCs, severity of leucopenia or thrombocytopenia, associated with the occurrence and severity of CIA.

      • Tumor Necrosis Factor-α 238 G/A Polymorphism and Risk of Hepatocellular Carcinoma: Evidence from a Meta-analysis

        Cheng, Ke,Zhao, Yu-Jun,Liu, Lian,Wan, Jing-Jing Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Background: Tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) plays a very important role in the development and progression of cancer. Many epidemiological studies have evaluated associations between the TNF-${\alpha}$ 238 G/A polymorphism and hepatocellular carcinoma (HCC) risk, but the published data are inconclusive. Therefore, we performed the present meta-analysis. Methods: Electronic searches of several databases were conducted for all publications on the association between TNF-${\alpha}$ 238 G/A polymorphism and HCC through July 2012. Asummary odds ratio (OR) with its 95% confidence interval (CI) were calculated to evaluate the strength of this association. Results: Eleven case-control studies with a total of 1,572 HCC cases and 1,875 controls were finally included in this meta-analysis. Overall, the TNF-${\alpha}$ 238 G/A polymorphism was significantly associated with increased risk of hepatocellular carcinoma in three genetic comparison models (For A versus G: OR 1.32, 95%CI 1.04-1.69, P = 0.02, $I_2$ = 40%; for AG versus GG: OR 1.32, 95%CI 1.02-1.71, P = 0.03, $I_2$ = 40%; for AA/AG versus GG: OR 1.33, 95%CI 1.03-1.72, P = 0.03, $I_2$ = 41%) when all studies were pooled. Subgroup analysis by ethnicity further showed that there was a significant association between the TNF-${\alpha}$ 238 G/A polymorphism and risk of HCC in Asians under three genetic comparison models (For A versus G: OR 1.30, 95%CI 1.00-1.68, P = 0.05, $I_2$ = 45% for AA/AG versus GG: OR 1.31, 95%CI 1.00-1.71, P = 0.05, $I_2$ = 46%). Conclusions: This meta-analysis provided convincing evidence that the TNF-${\alpha}$ 238 G/A polymorphism is associated with increased susceptibility to HCC. However, more well-designed studies with large sample size are needed to validate this association in Caucasians.

      • Identification of Prostate Cancer LncRNAs by RNA-Seq

        Hu, Cheng-Cheng,Gan, Ping,Zhang, Rui-Ying,Xue, Jin-Xia,Ran, Long-Ke Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.21

        Purpose: To identify prostate cancer lncRNAs using a pipeline proposed in this study, which is applicable for the identification of lncRNAs that are differentially expressed in prostate cancer tissues but have a negligible potential to encode proteins. Materials and Methods: We used two publicly available RNA-Seq datasets from normal prostate tissue and prostate cancer. Putative lncRNAs were predicted using the biological technology, then specific lncRNAs of prostate cancer were found by differential expression analysis and co-expression network was constructed by the weighted gene co-expression network analysis. Results: A total of 1,080 lncRNA transcripts were obtained in the RNA-Seq datasets. Three genes (PCA3, C20orf166-AS1 and RP11-267A15.1) showed a significant differential expression in the prostate cancer tissues, and were thus identified as prostate cancer specific lncRNAs. Brown and black modules had significant negative and positive correlations with prostate cancer, respectively. Conclusions: The pipeline proposed in this study is useful for the prediction of prostate cancer specific lncRNAs. Three genes (PCA3, C20orf166-AS1, and RP11-267A15.1) were identified to have a significant differential expression in prostate cancer tissues. However, there have been no published studies to demonstrate the specificity of RP11-267A15.1 in prostate cancer tissues. Thus, the results of this study can provide a new theoretic insight into the identification of prostate cancer specific genes.

      • Superior Hybrid Cathode Material Containing Lithium-Excess Layered Material and Graphene for Lithium-Ion Batteries

        Jiang, Ke-Cheng,Wu, Xing-Long,Yin, Ya-Xia,Lee, Jong-Sook,Kim, Jaekook,Guo, Yu-Guo American Chemical Society 2012 ACS APPLIED MATERIALS & INTERFACES Vol.4 No.9

        <P>Graphene-wrapped lithium-excess layered hybrid materials (Li<SUB>2</SUB>MnO<SUB>3</SUB>·LiMO<SUB>2</SUB>, M = Mn, Ni, Co, hereafter abbreviated as LMNCO) have been synthesized and investigated as cathode materials for lithium-ion batteries. Cyclic voltammetry measurement shows a significant reduction of the reaction overpotential in benefit of the graphene conducting framework. The electrochemical impedance spectroscopy results reveal that the graphene can greatly reduce the cell resistance, especially the charge transfer resistance. Our investigation demonstrates that the graphene conducting framework can efficiently alleviate the polarization of pristine LMNCO material leading to an outstanding enhancement in cell performance and cycling stability. The superior electrochemical properties support the fine hybrid structure design by enwrapping active materials in graphene nanosheets for high-capacity and high-rate cathode materials.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/aamick/2012/aamick.2012.4.issue-9/am301202a/production/images/medium/am-2012-01202a_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/am301202a'>ACS Electronic Supporting Info</A></P>

      • Improved kinetics of LiNi<sub>1/3</sub>Mn<sub>1/3</sub>Co<sub>1/3</sub>O<sub>2</sub> cathode material through reduced graphene oxide networks

        Jiang, Ke-Cheng,Xin, Sen,Lee, Jong-Sook,Kim, Jaekook,Xiao, Xiao-Ling,Guo, Yu-Guo The Royal Society of Chemistry 2012 Physical chemistry chemical physics Vol.14 No.8

        <P>An electronically conducting 3D network of reduced graphene oxide (RGO) was introduced into LiNi<SUB>1/3</SUB>Mn<SUB>1/3</SUB>Co<SUB>1/3</SUB>O<SUB>2</SUB> (LNMC) cathode material in a special nano/micro hierarchical structure. The rate test and cycling measurement showed that the hierarchical networks remarkably improve the high rate performance of LNMC electrode for lithium-ion batteries. The effect of RGO conducting networks on kinetic property was investigated by electrochemical impedance spectroscopy (EIS) and potentiostatic intermittent titration (PITT). The EIS results reveal that the RGO network greatly decreases the resistance of lithium batteries, especially the charge transfer resistance which can be attributed to the significantly improved conducting networks. The enhancement of apparent diffusion coefficient by the RGO conducting networks is shown by PITT. The power performance was found to be limited by the electrical conduction in the two-phase region, which can be greatly facilitated by the hierarchical RGO network together with carbon black. The as-obtained LNMC/RGO cathode exhibits an outstanding electrochemical property supporting the design idea of electronically conducting 3D networks for the high-energy and high-power lithium-ion batteries.</P> <P>Graphic Abstract</P><P>A 3D conducting network of reduced graphene oxide nanosheets is introduced into LiNi<SUB>1/3</SUB>Mn<SUB>1/3</SUB>Co<SUB>1/3</SUB>O<SUB>2</SUB> and is found to significantly promote the kinetics for Li storage. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cp23363k'> </P>

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