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Karina Karina,Krista Ekaputri,Johannes Albert Biben,Pritha Hadi,Hubert Andrew,Patricia Marcellina Sadikin 대한성형외과학회 2022 Archives of Plastic Surgery Vol.49 No.3
Although modern medicine hasmade great strides in the management of burn injuries, associated complications such as pain, infection, dyspigmentation, and scarring have yet to be fully dealt with. Although skin grafting and meshing are routinely performed on burn patients, this method poses a risk for adverse effects. Activated autologous platelet-rich plasma (aaPRP), which is increasingly used in the field of plastic surgery, contains growth factors beneficial for wound regeneration. Seven cases of burns with varying severity and conditions that were treated with intralesional subcutaneous injection and intravenous aaPRP are presented and discussed herein. This case series indicates that subcutaneous and intravenous aaPRP is a safe procedure with the potential to be an alternative when skin grafting cannot be done or as an adjunct treatment to skin grafting.
Synthesis and characterization of sol-gel derived ZrB2-ZrC compounds
Karina S. Campos 한양대학교 세라믹연구소 2014 Journal of Ceramic Processing Research Vol.15 No.6
In this work ZrB2-ZrC compounds were prepared by sol-gel process. These materials were examined by X-ray diffraction (XRD), thermogravimetric (TG) analysis, laser granulometry, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and nitrogen adsorption tests. Thermodynamic calculations were carried out using the FactSage® thermochemical software and databases. XRD revealed that ZrB2 and ZrC are the major phases present in the materials obtained in this study. It was observed that the relative amount of ZrB2 and ZrC in these samples can be tailored by controlling the concentration of H3BO3 in the starting solution. On one hand, laser granulometry and SEM tests revealed that the ZrB2- ZrC compounds prepared in this work show a coarse particle size distribution. On the other hand, they exhibited remarkable specific surface areas (about 150 m2 /g).
Histone Modifications During DNA Replication
Karina B. Falbo,Xuetong Shen 한국분자세포생물학회 2009 Molecules and cells Vol.28 No.3
Faithful and accurate replication of the DNA molecule is essential for eukaryote organisms. Nonetheless, in the last few years it has become evident that inheritance of the chromatin states associated with different regions of the genome is as important as the faithful inheritance of the DNA sequence itself. Such chromatin states are deter-mined by a multitude of factors that act to modify not only the DNA molecule, but also the histone proteins associ-ated with it. For instance, histones can be posttranslation-ally modified, and it is well established that these post-translational marks are involved in several essential nu-clear processes such as transcription and DNA repair. However, recent evidence indicates that posttranslational modifications of histones might be relevant during DNA replication. Hence, the aim of this review is to describe the most recent publications related to the role of histone posttranslational modifications during DNA replication.
Dietary Biotin Supplementation Impairs Testis Morphology and Sperm Quality
Karina Pasten-Hidalgo,Leticia Riveron-Negrete,Gloria Sicilia-Argumedo,Gustavo Canul-Medina,Tonatiuh Salazar-Anzures,Miguel Tapia-Rodrıguez,Enrique O. Hernandez-Gonzalez,Ana Lilia Roa-Espitia,Carlos Ce 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.5
Supplements containing pharmacological concentrations of biotin are commercially available over the counter. Classical toxicity studies have considered biotin administration as harmless; however, recent investigations have shown that biotin supplementation modifies tissue morphology without changes in toxicity markers, raising concerns about the consequences of morphological changes on tissues' functions and the safety of pharmacological concentrations of the vitamin. Testes are very sensitive to toxicants, and testicular histology is a reliable method to study its function. In this work, we investigated the effects of dietary biotin supplementation on testis morphology and spermatogenesis function using an experimental model, in which we have not observed unfavorable effects on other tissue functions or toxicity markers. Male BALB/cAnNHsd mice were fed a control or a biotin-supplemented diet (1.76 or 97.7 mg biotin/kg diet) for 8 weeks. Compared to the control group, the biotin-supplemented mice presented remarkable testis morphology changes, including increased spermatogonia layers; the cellular mechanism involved is related to increased proliferation. Sperm count and serum testosterone levels were not affected, but spermatozoa motility and morphology were significantly impaired in the biotin-supplemented mice. These results caution against the use of supplements with high concentrations of biotin and indicate that biotin's pharmacological effects on morphology need to be considered in toxicological studies.
Karina Uribe Hernández,Tzayhrí Gallardo Velázquez,Guillermo Osorio Revilla,Norma Almaraz Abarca,Maylet Hernández Martínez 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.4
Chemometric models using mid-infrared (MID-FTIR) spectroscopy were developed for detection and quantification of oxytetracycline and sulfathiazole contamination in honey samples. Low standard error of calibration (SEC) and prediction (SEP) values were achieved using a partial least squares algorithm (SEC= 1.02 and SEP=1.39 for oxytetracycline and SEC=1.24 and SEP=1.79 for sulfathiazole). Chemometric model-predicted concentrations of antibiotics were compared with ELISA results with coefficient of determination R2=0.8577 for oxytetracycline and R2=0.8216 for sulfathiazole. Classification of antibiotic contaminated honey samples and uncontaminated samples was carried out using Soft Independent Modeling Class Analogy analysis with a 100% correct classification rate with interclass distances in the range of 6.93-13.3. MID-FTIR chemometric models developed for detection and quantification of oxitetracycline and sulfathiazole in honey samples have been demonstrated.
The Role of Garlic in Metabolic Diseases: A Review
Karina G. Perez-Rubio,Miriam Mendez-del Villar,Marisol Cortez-Navarrete 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.7
Garlic (Allium sativum L.) is a popular spice that has been widely used for thousands of years in traditional medicine. Several organosulfur compounds in garlic have been linked to its beneficial effects on health. Evidence from preclinical studies and clinical trials supports garlic's antihypertensive, antidiabetic, antiobesity, and hypolipidemic effects. This study aims to summarize clinical trial evidence regarding the effects of garlic on metabolic diseases and its mechanisms of action.
Karina Korostelina,Yuji Uesugi 이화여자대학교 국제통상협력연구소 2020 Asian International Studies Review Vol.21 No.1
The paper explores how experts in Japan assess and understand the process and consequences of the unification of the Republic of Korea (South Korea) and the Democratic People’s Republic of Korea (North Korea). Based on the theoretical framework of interrelations between social identity and power, this paper asks how Japanese experts frame the process of Korean unification and evaluate its impact on Japan. The data was collected in Tokyo, Japan, through 37 semi-structured and focus group interviews, then examining these interviews using phenomenological and critical discourse analysis. Analysis of data reveals the existence of four competing narratives rooted in the complex relations between meaning of identity, concepts of power, and Japanese policies toward the unification process. The paper expands the description of two narratives currently present in the existing literature, (1) threat and (2) peace, and introduces two new narratives, (3) democratic processes and (4) restorative justice. The final discussion explores how three groups of factors, (1) regional dynamics, (2) domestic policy, and (3) possible models of unification, influence the prevalence of a particular narrative as well as resulting policies of Japan toward Korean unification.
Livelihoods for women in Mindanao : A post-conflict reconstruction approach
Karina R. SANTILLAN 이화여자대학교 아시아여성학센터 2015 Asian Journal of Women's Studies(AJWS) Vol.21 No.1
Mahigit dalawang milyong tao ang nawalan ng tahanan at lumikas dahil sa kaguluhan sa Mindanao noong 2000 hanggang 2009. Sa panandaliang paghupa ng kaguluhan, sila ay bumalik sa kanilang komunidad upang simulan ang proseso ng muling pagtatag ng kanilang buhay. Ihinahayag ng artikulong ito kung ano ang naiambag ng mga babae sa proseso ng pagtatag matapos ang kaguluhan. Ito ay isang pag-aaral kung paano nakatulong ang mga babae sa pamamagitan ng paglahok sa mga gawaing pangkabuhayan. Tinitignan nito ang kinahinatnan ng limang proyektong pangkabuhayan na naisakatuparan sa indanao sa mga taong 2000 hanggang 2010. Sinukat ang saklaw ng ambag ng mga kababaihan sa proseso ng pagtatag sa pamamagitan ng pagtukoy ng mga benepisyong naibigay nila sa kanilang pamilya at komunidad, na siyang naging bunga ng kanilang paglahok sa mga gawaing pangkabuhayan. Pinatotohanan ng artikulong ito na ang paglahok ng mga babae sa iba’t ibang gawaing pangkabuhayan ay nakatulong sa proseso ng pagtatag sa aspetong ekonomiko, sosyal at politikal ng mga komunidad na apektado ng kaguluhan. Ikinikumpara din ng artikulong ito ang paglahok ng mga babae sa mga gawaing pangkabuhayan sa ibang mga paraan ng pagtatag na naisakatuparan ng mga gobiyerno at mga ahensya. Isinusulong nito ang paglaan ng mga gawaing pangkabuhayan na hinihimok ang paglahok ng mga babae bilang isang mahusay ng paraan para maisakatuparan ang proseso ng pagtatag matapos ang kaguluhan. The conflict inMindanao has displaced over two million people in the period 2000 to 2009. As it subsides, the displaced return to their communities and begin the process of reconstruction. This paper studies how women contributed to the post-conflict reconstruction of Mindanao by engaging in livelihood activities. It explores five different livelihood intervention projects implemented in Mindanao between 2000 and 2010. The extent of women’s contribution to post-conflict reconstruction is measured by identifying the benefits gained at household and community levels, generated by women’s livelihood work. I argue that women’s participation in such activities have led to economic, social and political reconstruction of the communities affected by in Mindanao. This paper also compares the women’s livelihoods approach with other reconstruction strategies. It also illustrates that interventions for reconstruction therefore must include livelihood programs that encourage women’s participation, as exemplified by the experience of Mindanao.