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Asynchronous Control for Positive Markov Jump Systems
Kai Yin,Dedong Yang,Jiao Liu,Hongchao Li 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.2
A new result is provided for the asynchronous control analysis of positive Markov jump systems (PMJSs) in this paper. Firstly, a hidden Markov model is described to express the asynchronous circumstances that appear between the system modes and controller modes. Secondly, by utilizing a copositive stochastic Lyapunov function, a sufficient and necessary condition is given to guarantee the mean stability of PMJSs. Thirdly, we obtain another equivalent condition and design the corresponding asynchronous controller. Finally, the correctness of these results is verified by two numerical examples.
Power control of CiADS core with the intensity of the proton beam
Kai Yin,Wenjing Ma,Wenjuan Cui,Zhiyong He,Xinxin Li,Shiwu Dang,Feng Yang,Yuhui Guo,Limin Duan,Meng Li,Yikai Hou 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.4
This paper reports the control method for the core power of the China initiative Accelerator DrivenSystem (CiADS) facility. In the CiADS facility, an intense external neutron source provided by a protonaccelerator coupled to a spallation target is used to drive a sub-critical reactor. Without any control rodinside the sub-critical reactor, the core power is controlled by adjusting the proton beam intensity. Inorder to continuously change the beam intensity, an adjustable aperture is considered to be used at theLow Energy Beam Transport (LEBT) line of the accelerator. The aperture size is adjusted based on theProportional Integral Derivative (PID) controllers, by comparing either the setting beam intensity or thesetting core power with the measured value. To evaluate the proposed control method, a CiADS coremodel is built based on the point reactor kinetics model with six delayed neutron groups. The simulations based on the CiADS core model have indicated that the core power can be controlled stably byadjusting the aperture size. The response time in the adjustment of the core power depends mainly onthe adjustment time of the beam intensity
Kai Zheng,Guodong Zhang,Dongfang Zhou,Jianbing Li,Shaofeng Yin 전력전자학회 2018 JOURNAL OF POWER ELECTRONICS Vol.18 No.3
In this paper, a sliding mode and proportional plus integral (SM-PI) control combined with self-sustained phase shift modulation (SSPSM) for LLC resonant converters is presented. The proposed control scheme improves the transient response while preserving good steady-state performance. An averaged large signal model of an LLC converter with the ZVS modulation technique is developed for the SM control design. The sliding surface is obtained based on the input-output linearization concept. A system identification method is adopted to obtain the transform function of the LLC resonant converter, which is used to design the PI control. In order to reduce the inherent chattering problem in the steady state, the combined SM-PI control strategy is derived with fuzzy control, where the SM control is responsive during the transient state while the PI control prevails in the steady state. The combination of SSPSM and the SM-PI control provides ZVS operation, robustness and a fast transient response against step load variations. Simulation and experimental results validate the theoretical analysis and the attractive features of the proposed scheme.
RBM24 exacerbates bladder cancer progression by forming a Runx1t1/TCF4/miR-625-5p feedback loop
Yin Yue-Wei,Liu Kai-Long,Lu Bao-Sai,Li Wei,Niu Ya-Lin,Zhao Chen-Ming,Yang Zhan,Guo Ping-Ying,Qi Jin-Chun 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-
RNA–binding motif protein 24 (RBM24) acts as a multifunctional determinant of cell fate, proliferation, apoptosis, and differentiation during development by regulating premRNA splicing and mRNA stability. It is also implicated in carcinogenesis, but the functions of RBM24 in bladder cancer (BC) remain unclear. In the present study, we revealed that RBM24 was upregulated in BC tissues. Importantly, we found that a higher level of RBM24 was correlated with poor prognosis in BC patients. Overexpression of RBM24 promoted BC cell proliferation, while depletion of RBM24 inhibited BC cell proliferation in vivo and in vitro. Mechanistically, RBM24 positively regulated Runx1t1 expression in BC cells by binding to and enhancing Runx1t1 mRNA stability. Furthermore, Runx1t1 in turn promoted RBM24 expression by interacting with the transcription factor TCF4 and suppressing the transcription of miR-625-5p, which directly targets RBM24 and suppresses RBM24 expression. RBM24-regulated BC cell proliferation was moderated via the Runx1t1/TCF4/miR-625-5p feedback loop. These results indicate that the RBM24/Runx1t1/TCF4/miR-625-5p positive feedback loop participates in BC progression. Disruption of this pathway may be a potential therapeutic strategy for BC treatment.
Yin, Hang,Lu, Kai,Qiao, Wen-Bo,Zhang, Hai-Yang,Sun, Di,You, Qing-Shan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4
The purpose of this study was to investigate whether whole-liver radiotherapy plus a tumor-boost dose with concurrent chemotherapy is beneficial for colorectal cancer patients with massive and multiple liver metastases. From January 2007 to December 2012, 19 patients who exhibited massive (with a longest diameter > 5 cm) and invasive liver metastases and multiple metastases were treated with radiotherapy and concurrent chemotherapy. The total radiation dose was 53.4 Gy (range 38.8 Gy-66.3 Gy). All of the patients received a continuous intravenous dose of 5 fluorouracil (5-FU) 225 mg/m2 concurrently with radiation. The median survival time was 19 months. The 1- and 2- year overall survival rates were 78.3% and 14.3%, respectively. Of all of the patients who presented with abdominal pain, 100% experienced a decrease in pain. Decreases in the rates of ascites and jaundice were confirmed by ultrasound and bilirubin levels. No cases of Grade 4 or 5 acute or late toxicity were recorded. There were only two cases of Grade 3 toxicity (elevated bilirubin). These data provide evidence that whole-liver radiotherapy plus a tumor-boost dose with concurrent chemotherapy is beneficial for colorectal cancer patients with massive and multiple liver metastases.
Yin Congbo,Pan Hao,Zhang Zhendong,Zhu Haibing,Shen Kai 한국자동차공학회 2021 International journal of automotive technology Vol.22 No.5
A turbocharged GDI engine with variable intake tumble is used to study the effects of EGRcombined with enhanced tumble on the engine’s economy, power, and emissions characteristics. The effects of EGR with enhanced intake tumble flow, on the combustion phase, combustion duration, knock index and combustion cycle variation of the engine, were studied at two speeds of 1500 r/min and 2000 r/min from low to medium and to full load. The research shows that although the commercial engine has been well calibrated and optimized, the optimization of EGR and enhanced tumble flow together with the optimization of the ignition angle can improve the engine’s economy and emission characteristics, while maintaining relatively fast burning speed and low combustion cycle variation. From medium to heavy load, the economy can be improved by 2.6 ~ 10 %, and the minimum fuel consumption can be reduced to 213 g/kW.h (ƞe = 36.8 %). At the same time, the increase of the combustion cycle variation is controlled within 5 %, but as the load and the EGR ratio increase, the power loss cannot be compensated by the advance of the ignition angle. The 6 ~ 21 % EGR ratio brings 3.5 ~ 9 % power loss.
Polishing Characteristics of MnO2 Polishing Slurry on the Si-face of SiC Wafer
Tao Yin,Tosiro Doi,구로가와슈헤이,Zhao zhong Zhou,Kai ping Feng 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.12
To realize an efficient and high-quality chemical-mechanical polishing process for the surface of a SiC wafer, a new type of MnO2 slurry is developed employing the multi-valence and oxidation-reduction characteristics of MnO2 particles. This slurry is utilized to polish the Si-face of SiC wafers. In this paper, the influences of the polishing particle concentration and the pH of slurry on MRR are analyzed, the polishing performance of the MnO2 slurry is studied, and the polishing mechanism of the MnO2 slurry on the SiC wafer is determined. The polishing mechanism of the MnO2 slurry is verified by selecting commonly used additives, such as KMnO4, and the influence of the additive amount on the MRR is analyzed. Finally, the surface morphology of the material after polishing is observed with analytical instruments. The experimental results show that the MRR of the MnO2 slurry is highly dependent on the pH value of the slurry. The MnO2 particles tend to convert into MnO4 - ions in an alkaline environment, and the strong oxidizing property of MnO4 - ions greatly improves the polishing efficiency. As the MnO4 - ion concentration increases, the MRR can reach over 600 nm/ h, and an ultra-smooth surface with a surface.
Liu, Kai,Zhang, Hao,Ng, Joseph Kee-Yin,Xia, Yusheng,Feng, Liang,Lee, Victor C. S.,Son, Sang H. IEEE 2018 IEEE TRANSACTIONS ON INDUSTRIAL INFORMATICS - Vol.14 No.3
<P>This work aims at proposing a transfer learning (TL)-based framework to enhance system scalability of fingerprint-based indoor localization by reducing offline training overhead without jeopardizing the localization accuracy. The basic principle is to reshape data distributions in the target domain based on the transferred knowledge from the source domains, so that those data belonging to the same cluster will be logically closer to each other, whereas others will be further apart from each other. Specifically, the TL-based framework consists of two parts, metric learning and metric transfer, which are used to learn the distance metrics from source domains and identify the most suitable metric for the target domain, respectively. Furthermore, this work implements a prototype of the fingerprint-based indoor localization system with the proposed TL-based framework embedded. Finally, extensive real-world experiments are conducted to demonstrate the effectiveness and the generality of the TL-based framework.</P>