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Jung, Keun‐,Hwa,Chu, Kon,Lee, Soon‐,Tae,Park, Kyung‐,IL,Kim, Jin‐,Hee,Kang, Kyung‐,Muk,Kim, Soyun,Jeon, Daejong,Kim, Manho,Lee, Sang Kun,Roh, Jae‐,Kyu Blackwell Publishing Ltd 2011 Epilepsia Vol.52 No.3
<P><B>Summary</B></P><P><B>Purpose: </B> Children who experience complex febrile seizures are at a higher risk of subsequent epileptic episodes, and they may require therapy. This issue can be resolved by interventional studies using molecular targets identified and defined in animal models. In the current study, the molecular changes in the rat brain after febrile seizures were examined throughout the latent period, and erythropoietin was administered as a potentially antiepileptogenic intervention.</P><P><B>Methods: </B> The changes in the expressions of genes that were differentially regulated during the latent period after febrile seizures were categorized into the following four patterns: (1) continuously high (CH); (2) continuously low (CL); (3) rise and fall (RF); and (4) going‐up (GU). Erythropoietin was administered immediately after seizure cessation and then once daily for at most 7 days, and spontaneous recurrent seizures and cellular and molecular changes were investigated.</P><P><B>Key Findings: </B> The CH genes were associated with cell cycle and adhesion, whereas the CL genes were related to energy metabolism. Within the category of RF, the largest changes were for genes involved in inflammation, apoptosis, and γ‐aminobutyric acid (GABA) signaling. The GU category included genes involved in ion transport and synaptogenesis. Along with an early rise in inflammatory genes, there were substantial increases in brain edema and activated microglia during the early latent period. Erythropoietin reduced the early inflammatory responses and modulated the molecular alterations after febrile seizures, thereby reducing the risk of subsequent spontaneous seizures.</P><P><B>Significance: </B> Erythropoietin treatment may provide a new strategy for preventing epilepsy in susceptible individuals with atypical febrile seizures.</P>
EXPERIMENTAL INVESTIGATION OF THE POSITIVE ROLE OF BLOCKCHAIN IN SOCIAL EXCHANGE
Jungkeun Kim,Areum Cho,Daniel Chaein Lee,Suh-Young Irene Park,Jaehoon Lee,Jooyoung Park,Jihoon Jhang 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07
The study investigates how the presence of blockchain technology affects social fairness and selfish monetary decisions. Based on the assumption that blockchain technology enhances transparency and traceability in social exchanges, the study predicts that individuals will make less selfish decisions when blockchain is present. To test these predictions, the study conducted three experiments using a modified version of the dictator game scenario where participants decide how to divide a sum of money among themselves. In Study 1, the results show that individuals took less money for themselves and allocated more to the third player when blockchain technology was present, and the importance of social fairness was higher under the blockchain-presence condition. The mediation analysis indicates that the increase in social fairness mediates the effect of blockchain technology on monetary decisions. Study 2 replicated Study 1 with real monetary incentives. The results showed that individuals took less money for themselves only under the blockchain-image condition, and the importance of social fairness was higher only under the blockchain-image condition. Study 3 examined the moderating effect of the first player's allocation on participants' behavior under the presence or absence of blockchain technology. The study provides empirical evidence that blockchain technology can positively influence social fairness and reduce selfish monetary decisions. The findings have implications for policymakers and blockchain developers to design and implement blockchain systems that promote transparency and traceability in social exchanges, thereby enhancing social fairness.
The Effect of CAPTCHA Exposure on Traveler's Online Behaviors
Jungkeun, Kim,Suh-Young Irene, Park,Jihoon, Jhang Smart Tourism Research Center 2022 Journal of smart tourism Vol.2 No.4
CAPTCHA (Completely Automated Public Turing test to tell Computers and Humans Apart) is everywhere. This research explores whether and how travelers' upfront exposure to a CAPTCHA influences their subsequent behaviors. In the travel decision-making context, we investigated the relationship between CAPTCHA and travelers' hotel preferences and intent to use cryptocurrency during the trip. In two experimental studies, we found that travelers exposed to a CAPTCHA (vs. not) preferred a robot-staffed to a human-staffed hotel (Study 1) and a pro-environmental to a quality hotel (Study 2). Exposure to a CAPTCHA also influences travelers' intent to use cryptocurrency during travel (Study 2). Preference for a pro-environmental hotel does not depend on the formats of CAPTCHA ("I am not a robot" or "I am human") while intent to use cryptocurrency is higher when travelers were exposed to the "I am not a robot" than "I am human" CAPTCHA. The results of two exploratory studies suggest several potential mechanisms by which CAPTCHAs affect travelers' behaviors and call for more research on this topic.
Jungkeun Kim,Jooyoung Park,Daniel Chaein Lee,Aekyoung (Amy) Kim,Jihoon Jhang,Areum Cho,Jaehoon Lee 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07
The market for counterfeit luxury goods is growing rapidly, with estimates suggesting that counterfeit trades are valued at around $4.5 trillion globally, with 60% to 70% of this being made up of counterfeit luxury goods. Research has shown that counterfeits dilute the perceived quality of luxury brands and reduce consumers' purchase intentions. Non-fungible tokens (NFTs) are a form of ownership record that is linked and stored on a blockchain.
EVALUATION OF MULTIPLE VARIATIONS WITH NONFUNGIBLE TOKENS (NFTS): IMPORTANCE OF UNIQUENESS
Jungkeun Kim,Daniel Chaein Lee,Jaehoon Lee,Jihoon Jhang,Jooyoung Park 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07
This paper examines how consumers evaluate digital products with multiple Non-fungible Tokens (NFTs), which are blockchain-enabled cryptographic assets that represent proof-of-ownership for digital objects. The study predicts that people prefer fractioned NFTs (unique fractions of a digital object) versus duplicated NFTs (identical digital objects with distinct numbers) due to their preference for uniqueness. The study also examines the moderating role of product attributes, predicting that preferences for fractioned NFTs will be reduced when the product provides unique aspects, such as a serial number.
CONSUMERS EVALUATION FOR THE PRODUCTS WITH BLOCKCHAIN: THE ROLE OF KNOWLEDGE AND QUALITY OF PRODUCTS
Jungkeun Kim,Jeong Hyun Kim,Jaeseok Lee,Jihoon Jhang,Changju Kim,Jooyoung Park 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07
Blockchain is an immutable ledger that records transactions and tracks assets using a common communication protocol. It stores a copy of the blockchain and implements a consensus function to verify transactions. Blockchain is applied to industries beyond finance, such as retail, to maintain security and transparency. Consumers with knowledge of blockchain technology are likely to be affected when evaluating products with blockchain embedded, impacting their product evaluation. The study investigates the impact of blockchain technology on consumers' product evaluation and how knowledge of blockchain and product quality moderate its effects.
A numerical simulation for reduction of rudder cavitation with gap flow blocking bars
Jungkeun Oh,Seung-Hee Lee,Sang-Hyun Kim,Dae-Won Seo 대한조선학회 2012 International Journal of Naval Architecture and Oc Vol.4 No.2
In recent practices, a half circular prismatic bar protruding beyond the concave surface of the horn facing the gap has been formed along the centerplane of a rudder to lessen the gap flow between the horn and the movable portion of the rudder system. If a flow through the gap of a rudder is reduced considerably through this approach, previous numerical studies indicate that not only the gap flow but also the rudder cavitation can be noticeably diminished. In the present study, numerical simulations on two-dimensional rudder sections were performed to show that the blocking ability of the single centre bar can be improved by the proper choice of sectional shape. Moreover, a pair of blocking bars attached symmetric to the centerplane on the opposite convex surface of the movable portion is suggested in the study as well, to circumvent the difficulties arising from the practical application of the single centre bars. The bars are placed near the outer edges of the gap easily accessible at the maximum rudder angle to allow simple installation of the device during a maintenance period of a ship. It is found that the pair of blocking bars further improves the blocking effects and application to a practical three-dimensional rudder also backs up the fact.