Effect of Oriental & Western Anti-Stress Agents on the Changes of the Salivary Gland of Rats under Restraint Stress

Hong, Jung-Pyo 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Jung-Pyo Hong. Department of Oral Diagnosis and Oral Medicine, College of Dentistry, Kyung Hee University, Seoul, Korea. Effect of Oriental & Western Anti-Stress Agents on the Changes of the Salivary Gland of Rats under Restraint Stress. Proceedings of International Symposium on East-West Medicine, Seoul. 162-171, 1999.-Stress caused the changes in the neural, vascular and immune system of the body. If stress is mild so as not to exceed the adaptability of the body to it, the homeostasis of the body is maintained. Otherwise psychological and physical disturbances of the body may occur, ample evidence suggests that stress causes apoptosis of the cells, inducing morphological and functional changes of the tissue as the result of tissue destruction. These disorders are also frequently observed in the orofacial region(dentistry), including not only such paychological oral lesions as Iichen planus and geographic tongue but stress-related diseases like temporomandibular disorder and xerostomia. It is, Therefore, possible that anti-stress medicines and stress-reliving activities may prevent and treat the psychosomatic disorders. In the study, we intended to check whether anti-depressant and anti-stress drugs such as Fluoxetine, Bunsimkium and Bohyulanshintang(oriental herbal medicine) can prevent pathologic changes of the salivary gland under the restraint condition. Seven-week old sprague-Dawley rats were divided into 5 groups.: Group Ⅰ, normal control;GroupⅡ,rats were under the restraint stress placed in the stress cages; GroupⅢ, rats were administrated Fluoxetine (5mg/kg/day), p.o., under the restraint stress; GroupⅣ,rats were administrated Bunsimkium, p.o., for 10 days before applying the restraint stress also.; Group Ⅴ,rats were administrated Bohyulanshintang, p.o., for 10 days before they were placed under the restraint stress. The rats were sacrificed at day 0,1,3,5,7 of the experiment. The submandibular glands of the rats were sampled immediately. The levels of clusterin protein and mRNA in the tissues were measured by immunohistochemistry and Northen blot analysis respectively. Our results were as follows. 1. Restraint stress induced apoptosis of the submandibular gland. 2. Restraint stress induced the expression of clusterin. The expression of clusterin reached the maximum level when the cellular apoptosis apparent and decreased after then. 3. Apoptosis was occurred on the acinar cells earlier than ductal cells by restraint stress. 4. In the Northern blot and immunohistochemistry, noremarkable difference of clusterin was found in between the normal control group and the Fluoxetine administrated-restraint stress group. 5. In Bunsimkium administrated-restraint stress group, apoposis was delayed. 6. In the Bohyulanshintang administered-restraint stress group, expression of clusterin increased with time and reached the maximum level at day 5 of the experiment and decreased after then. But apoptosis did not occurthrough all days of the experiment. The overall results suggenst that stress can induce pathologic changes in the salivary glands. By an early response to stress, clusterin is expressed in the glands to protect the glandular cells form the stress. But if stress is so strong and prolonged as to exceed the stress adaptability of the cells, then the cells may undergo apoptosis instead of producing clusterin. Administration of stress-relieving drugs such as Fluoxeting, BunsimKium and Bohyulanshintang may be useful in preventing and treating stress-related salivary glands diseases. Our results are thought to be useful to identify the mechanism of stress-related salivary gland diseases such as xerostomia. Hereafter, among the anti-stress medicines such as western medicine and traditional herb medicine, Bohyulanshintang with minimal side effect could be applied to effectively prevent and treat psychosomatic disease.

연구논문 : 근대(近代) 문학(文學)에 나타난 신화적(神話的) 상상력(想像力) 연구(硏究) - 이효석, 이상, 김유정 다시읽기 -

표정옥 ( Jung Ok Pyo ) 시학과 언어학회 2007 시학과 언어학 Vol.13 No.-

<비보이를 사랑한 발레리나1)>와 김유정 문학의 축제적 상상력 연구 -놀이적 상상력과 축제적 상상력의 상호 연관을 통해-

표정옥 ( Jung Ok Pyo ) 대구가톨릭대학교 인문과학연구소 2008 인문과학연구 Vol.9 No.-

무대공연 불안 척도의 통계적 검증

표내숙,김정숙,류민정,조대용 釜山大學校 附設 體育科學硏究所 2004 體育科學硏究所 論文集 Vol.20 No.-

The purpose of this study was to confirm attention of questionnaire by analyzed whether question items are suited to stage performance anxiety and recognized validity of questionnaire about stage performance anxiety which is obtained with corrected the questionnaire to be appropriate to suit the subject based on sport competition anxiety scale by Smith, Smoll, and Schutz(1990).....

무용수의 공연불안감 측정도구 개발

표내숙,김정숙,표종현 釜山大學校 附設 體育科學硏究所 2002 體育科學硏究所 論文集 Vol.18 No.1

This study prepared a questionnaire for the measurement of dancers' anxiety about dance performance, based on a similar questionnaire of sports competition anxiety developed by Smith et al.(1990). The questionnaire as prepared here contained question items for the measurement of dancers' anxiety, worry and distraction. The question items were applied to survey respectively 70, 50 and 62 dance students at colleges in Busan over three sessions. The validity of the questionnaire was verified through the exploratory factor analysis and by using Cronbach αcoefficient. Cronbach αcoefficients for the questionnaire developed in this study were found ,7650 for 'distraction', .6480 for 'anxiety' and .6305 for 'worry', suggesting that the questionnaire was reliable in measuring dancers' anxiety about dance performance. Data from th survey as above mentioned showed that dancers were different with each other in such anxiety according to their cognitive and physical senses of dance stage and performance. The data also showed that such psychological aspect of dancers was influenced by their dance experience, dance career and personality, a performance place, stage settings, the tempo of performance music and stage costumes. There were no differences among dancers in anxiety according to their dancer career. In other words, dance career itself had nothing to do with dancers' confidence in performance. Despite they obtain high skills of dance expression by repeating dance practice, dancers tend not to be able to use such skills to the utmost in actual performance due to stresses and strains under a changed situation. This may be referred to as control confusion by personal, psychological anxiety rather than as lack in technical dance skills. It may also be regarded as a psychological state of stage fright(state anxiety in dance performance) dancers face when they do not practice dance in a closed space but meet the audience on actual dance stages. In relation, it was reported that dancers with high trait anxiety were higher in stage anxiety scores during dance practice and during and after dance performance than those with low trait anxiety. Meanwhile, it was suggested that a form of the psychological test of dancers considering characteristic of stage performance should be developed and that cognitive concepts of dance be actively studied. In conclusion, dance performance should be made only after dance practice which ensures harmony between physical and psychological aspects. Now the researcher would survey dancers by using a questionnaire for the measurement of dance performance anxiety, whose validity is clearly verified, and modify and supplement the questionnaire to raise its reliability. The the researcher would conduct a more profound study about effects of such anxiety as mentioned above on dance performance.

삼국유사에 재현된 여성의 양성성에 대한 현대적 문화 담론 연구 : <기이편>에 등장하는 여성을 중심으로

표정옥 가톨릭대학교 인간학연구소 2011 인간연구 Vol.0 No.20

정신과 의약분업에 대한 5년 후 추적조사

박정수,정재열,홍진표,백기청,박영현,박종익 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.4

Objectives : This study is designed to discuss the pros and cons related to the 'separation of drug prescription and dispensation' system when 5 years have passed by since the introduction of this system. Methods : The 592 psychiatrists from 1,107 working places took part in nationwide survey by mail or E-mail from June to September, 2005. The response rate was 23.8%, most of respondents came from private clinics. Results : The average age of psychiatrist was 44.6 years old, ranging from 25 to 75, most of them was predominantly male. The main results were as followings : 1) The ratio of psychiatric prescription out of hospital based on out-patients departments was the lowest in clinics, following by hospitals, general hospitals and university hospitals by order. 2) The main reasons of customer's preference for out of hospital prescription were economic advantage and self-awareness of prescription. As for the disliking for it, the most complaints were the anxiety about disclosure of psychiatric treatment, in convenience for delay and concern about drug change. Conclusion : Five years didn't seem to give a change on how the psychiatrists perceive the 'separation of drug prescription and dispensation' system at all. The confidentiality and human right issues on the part of psychiatric patients should never be ignored in order to manage this system successfully.

교잡종 찰옥수수에 대한 연구 III : Ⅲ. 국내 옥수수 유전자원 수집종에 대한 주요 특성 분포

서정은,주현민,최윤표,홍범용,조양희,주정일,지희정,이희봉 충남대학교 농업과학연구소 2007 농업과학연구 Vol.34 No.2

2006년 국내 각 지역으로부터 수집된 재래종옥수수 유전자원을 관행방법에 의해 파종하고 주요특성별로 분포도를 살펴본 결과는 다음과 같다. 1. 수집된 유전자원에 대한 발아율은 대부분 80∼100%이상의 분포를 보였으나, 일부 수집계통에는 30% 미만의 극히 저조한 발아율을 보였다. 2. 수집자원에 대한 초기생육을 살펴보면 극히 생육이 저조한 것이 40% 정도를 보였고, 극히 우수한 자원은 3%미만으로 나타났다. 3. 간장은 대부분이 150∼199cm범위에 55%가 분포하고 있었으나, l00cm이하가 5%, 250cm이상이 8%로 나타나 수집종간에 큰 차이를 보였다. 4. 주당 분얼수는 1개 미만이 40%의 분포를 보였으나, 일부 수집종에서 2 내지 3개의 분얼수를 보이는 계통이 확인되었다. 5. 개화소요일수는 61∼64일의 범위에서 40%, 57∼60일의 범위에서 30%의 분포를 보였으며, 특히 일부 수집종의 경우 55일 이하의 극조생종도 10% 정도의 분포를 보였다. 6. 이삭길이는 대부분 11∼15cm범위에 60%가 포함되어 있으나, 일부계통에서 5cm미만이 2%, 16∼20cm의 이삭길이도 10%가 분포하였다. Germination ratio on the 300 collected genetic resources showed 80 to 100 percentage, but those of some accessions were very low as below 30 percentage. Early growth phase of most of these lines were very poor while some collected lines were very vigor. Range of stem height showed from 150 to 199cm, but that of some accessions showed below 100cm as five percentage and some of them was over 250cm as eight percentage. Number of tillers per plant appeared less one but some collected lines have two to three tillers per plant. In days to tasseling, some accessions showed more four per plant. Ear length of these accession showed above 60 percentage as 11 to 15cm, while that of some collected lines showed over 10 percentage as 16 to 20cm.

UWB 신호를 사용한 사용자 위치추적

김기표,최정식,변건식 東亞大學校附設 情報技術硏究所 2004 情報技術硏究所論文誌 Vol.12 No.1

Although, the GPS using for user location tracking has many advantages of chasing the target in a wide area, the GPS has defect as is isn't able to chase the location in doors or basements. To make up for it's defect, we need to use the UWB signal. The UWB has not a very wide bandwidth, but low signal level under noise level and it can pass through a wall. In this report, using the time delay we simulate indoor position tracking system to chase a user among people in a building when signal is in progress

유도선수들의 스포츠자신감 수준이 귀인형태에 미치는 영향

홍재표,차정훈,전승훈 한국스포츠리서치 2005 한국 스포츠 리서치 Vol.16 No.2

The present study was designed to examine the effect of sport-confidence on attributional perceptions across male and female fencers. Judo athletes reported their sport-confidence, attribution perceptions on Sport-Confidence Inventory. CDSⅡ(Causal Dimension Scale Ⅱ) According to the previous research findings related to the theme of the study, it was hypothesized that the independent variables of trait sport-confidence. state sport-confidence influence the dependent variable of attributional perceptions. and the relationships between the two kinds of variables were examined using two-way ANCOVA. The implications of the study are as follows : Firstly. Trait sport-confidence and state sport-confidence of judo athletes significantly affected the locus of contorl dimension. Secondly. Trait sport-confidence and state sport-confidence of judo athletes significantly affected the stability dimension. Thirdly, Trait sport-confidence and state sport-confidence of judo athletes significantly affected the contro lability dimension.