1920년대 소설의 시간구조에 관한 연구 : <술권하는 사회><감자>를 중심으로

정덕준 고려대학교 한국학연구소 1988 한국학연구 Vol.1 No.-

사과나무 腐爛病 防除에 關한 硏究 : 腐爛病源菌의 生育抑制에 미치는 化學藥劑, 抗生劑 및 生藥抽出物의 效果 The effects of Chemical Compounds, Antibiotics and Extracts of Herbal Plants on the Growth Inhibition of Valsa ceratosperma Strains

정재훈,양덕춘 경희대학교 부설 식량자원개발연구소 1990 硏究論文集 Vol.11 No.-

These studies were conducted to control of apple cankers caused by Valsa ceratosperma strains by treatment of chemical compounds, antibiotics, extracts of herbal plants and compounds produced from mutant of Streptomyces melanosporofaciens. Effects of chemical control for apple canker were evaluated by grwoth inhibition of Valsa ceratosperma on the PDA media and the most effective chemical was found to be berberine followed by neoasogin, branchi Q, in general. Inhibitory concentration of Valsa ceratosperma was 500mg/ℓ in berberine, and l0,000mg/ℓ in neoasogin. The antifungal antibiotic, cycloheximide, was effective for growth inhibition of Valsa ceratosperma; all strains were inhibited on the media with l00㎍/㎖ of cycloheximide and M26 strain was inhibited by lower concentration of 10㎍/㎖. Effects of extract of herbal plants for growth inhibition of Valsa ceratosperma were excellent with Phellodendron amurense and Coptis japonica, and especially in Coptis japonica, low concentration of l,000mg/ℓ was effective. Compounds produced from mutant of S. melanosporofaciens for growth inhibition of Valsa ceratosperma were more effective than other compounds, i.e., chemical compounds, antibiotics and extracts of herbal plants. Minimum inhibitory concentration of compound C-1 for IF03025 and M1099 was 31.25㎍/㎖.

사과나무 腐爛病 防除에 關한 硏究 : 腐爛病源菌의 生育抑制에 미치는 化學藥劑, 抗生劑 및 生藥抽出物의 效果 The Effects of Chemical Compounds, Antibiotics and Extracts of Herbal Plants on the Growth Inhibition of Valsa ceratosperma Strains

정재훈,양덕춘 경희대학교 유전공학연구소 1990 遺傳工學論文集 Vol.2 No.-

These studies were conducted to control of apple cankers caused by Valsa ceratosperma strains by treatment of chemical compounds, antibiotics, extracts of herbal plants and compounds produced from mutant of Streptomyces melanosporofaciens. Effects of chemical control for apple canker were evaluated by growth inhibition of Valsa ceratosperma on the PDA media and the most effective chemical was found to be berberine followed by neoasogin, branchi Q, in general. Inhibitory concentration of Valsa ceratosperma was 500㎎/ℓ in berberine, and 10,000㎎/ℓin neoasogin. The antifungal antibiotic, cycloheximide, was effective for growth inhibition of Valsa ceratosperma; all strains were inhibited on the media with 100㎍/㎖ of cycloheximide and M26 strain was inhibited by lower concentration of 10㎍/㎖. Effects of extract of herbal plants for growth inhibition of Valsa ceratosperma were excellent with Phellodendron amurense and Coptis japonica, and especially in Coptisjaponica, low concentration of 1,000㎎/ℓ was effective Compounds produced from mutant of S melanosporofaciens for growth inhibition of Valsa ceratosperma were more effective than other compounds, i.e., chemical compounds, antibiotics and extracts of herbal plants. Minimum inhibitory concentration of compound C-1 for IF03025 and M1099 was 3125㎍/㎖.

酸棗仁이 CT105에 의한 신경세포 상해 및 白鼠의 기억에 미치는 영향

정정욱,박창국,박치상,이소연,윤현덕,신오철 대한본초학회 2005 大韓本草學會誌 Vol.20 No.1

Objective: This study was designed to research whether demonstrate neuroprotective and memory enhancing effects of Z1BU, suggesting its beneficial actions for the treatment of AD. Methods: The present study investigated effects of the dichloromethane extract of Semen Zizyphi Spinosae(ZIBU) on neurotoxicity and reactive oxygen species(ROS) and nitric oxide(NO) formation in PC 12 cell line overexpressed with carboxyl-terminal 105 amino acid peptide fragment of amyloid precursor protein(CT105). In addition, the present study evaluated its radical scavenging activity and effects on acetylcholinesterase(AChE) activity. Furthermore, effects on neuronal loss in CAl area and cognitive deficits induced by scopolamine treatment were also evaluated in rats. Result: we found in this study that ZIBU significantly inhibited apoptotic neuronal death induced by CT105 overexpression in PC12 cells, with the IC_(50) value of 23 ㎍/ml. Based on phase-contrast and fluorescence microscopic examinations, ZIBU reversed morphological changes of CT105-expressed PC-12 cells. It was also found that Z1BU significantly induced neurite outgrowth and inhibited formation of ROS and NO.Z1BU scavenged DPPH radicals and inhibited AChE activity. Furthermore, it attenuated memory impairment induced by the injection of scopolamine in rats, based on passive avoidance test. Crystal violet staining of rat brain slices exhibited increase in the viability of pyramidal neurons in hippocampal CAI area. Conclusion: these results demonstrate neuroprotective and memory enhancing effects of ZIBU, suggesting its beneficial actions for the treatment of AD.

기술 교과의 ICT 활용 교육을 위한 XML 교수문서시스템의 설계 및 구현

정덕길,이종구,한순희 한국컴퓨터교육학회 2003 컴퓨터교육학회 논문지 Vol.6 No.4

21세기의 교육은 교육 정보화를 기반으로 한 연계·통합 교육으로 발전되고 있으며, ICT 활용교육이 교수-학습 전략과 유형을 제시하며, 기술교과의 수업 지도안에 대한 효율적인 XML 문서 생성 및 저장 시스템에 대한 구현 방안을 제시한다. 그리고 이 논문에서 구현된 XML 교수 문서 시스템을 적용하여 교육 자료의 효율적인 관리과 저장성을 높이고, 동일 업무에 대한 교육 자료의 재편집 과정을 감소시킴으로써 교육 자료의 가치를 높일 수 있는 가능성을 확인하였다. The education of 21st century is developed to the closely connected and integrated education, and the ICT applied education is suggested as an approach to teaching-learning method. In this paper, we suggest an teaching-learning pattern and strategy of Technology course as an example of the ICT applied education, and provide an implementation for the efficient XML document creation and storage system of teacher’s subject data. And we have confirmed the utilization of this system which it improves the efficient management and preservation of educational data and also it raises the value of educational data by decreasing the burden of re-editing the educational documents for similar business.

채택 빈도수에 의한 교육용 소프트웨어 품질평가 준거의 설정 및 분석

정덕길,이태군 한국컴퓨터교육학회 2004 컴퓨터교육학회 논문지 Vol.7 No.1

교육용 소프트웨어가 갖는 여러 가지의 우수한 기능과 장점에도 불구하고 실제적으로 학습 현장인 학교와 가정에서 교육용 소프트웨어의 활용도가 저조한 현상은 교육용 소프트웨어가 교육 전문가나 컴퓨터 소프트웨어 개발 전문가의 입장에서 연구되고 개발되어 학습자의 요구사항이 교육용 소프트웨어에 제대로 반영되지 못한 결과로 볼 수 있다. 이에 따라 이 연구에서는 교육용 소프트웨어의 평가 도구들이 소비자의 요구를 얼마나 수용하고 있는지 알아보는 사전 연구의 일환으로서, 국내외에서 발표된 기존의 교육용 소프트웨어의 평가 도구들이 중요하게 다루고 있는 평가 준거는 무엇인지 교육용 소프트웨어의 평가 도구에서 채택된 빈도수를 통하여 조사 분석하였다. 그리고 이 분석 결과와 비교하여 교육용 소프트웨어의 실수요자인 학습자들은 교육용 소프트웨어에 대한 기존의 품질 평가 도구가 가지고 있는 품질 평가 준거를 어느 정도의 차이점을 가지고 중요하게 생각하는지에 대하여 조사하고 분석하였다. In spite of various good functionalities and merits of educational software products, they are generally not used widely in school and home, One of these reasons is which many of the educational software products are developed by educational professionals without adequate consideration to the requirement of learners. So, in this paper, in order to see the degree of how much learner’s requirement have been met in educational software products, we survey and analyze the evaluation criteria based on the adoption frequencies which have been searched out from domestic and foreign educational software evaluation tools. And, by the learner-centered survey, we compare and analyze the difference of quality estimation criteria for educational software between the viewpoints of students and the selected evaluation criteria treated as important in educational software evaluation tools.

Candida parapsilosis 돌연변이주에 의한 Xylitol 생산의 배지조건 최적화

오덕근,윤상현,김정민,김상용,김정회 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.4

Candida parapsilosis ATCC 22019 돌연변이주를 사용하여 xylitol 생산에 영향을 주는 배지성분의 최적화를 수행하였다. Xylose 50 g/l 배지에서 여러 가지 질소원이 xylitol 생산에 미치는 영향을 살펴본 결과 xylitol 생산에는 무기질소원으로는 (NH_4)_2SO_4가 좋았으며 유기질소원으로는 yeast extract가 가장 좋았다. 무기염으로 KH_2PO_4 ad MgSO_4·7H_2O를 선정하여 최적화를 수행하였고 그 결과 최적배지로 xylose of 50 g/l, yeast extract of 5 g/l, (NH_4)_2SO_4 of 5 g/l, KH_2PO_4 of 5 g/l, MgSO_4·7H_2O of 0.2 g/l로 결정하였다. 최적배지를 사용하여 발효조에서 64시간 배양하였을 때 xylose는 모두 소모되었으며 최종 균체농도와 xylitol 생산량은 각각 7.6 g/l와 37 g/l을 얻었다. 이때, xylose로 부터 xylitol의 전환수율 74%이었고, xylitol의 생산성은 0.58 g/l-hr이었다. 최적배지에서 총 첨가된 xylose에 대한 xylitol의 생산수율 80.7%에 해당되었고 xylitol의 생산성은 0.94g/l-hr에 해당되었다. Medium optimization for xylitol production from xylose by Candida parapsilosis ATCC 22019 mutant was performed. Effect of various nitrogen sources on xylitol production was investigatied. Of inorganic nitrogenous compounds, ammonium sulfate was effective for xylitol production and yeast extract was the most suitable orangic nitrogen nutrient for enhancement of xylitol production. Effect of inorganic salts such as KH_2PO_4 ad MgSO_4·7H_2O on xylitol production was also studied. Optimal medium was selected as xylose of 50 g/l, yeast extract of 5 g/l, (NH_4)_2SO_4 of 5 g/l, KH_2PO_4 of 5 g/l, MgSO_4·7H_2O of 0.2 g/l. In a fermentor by using the optimal medium, a final xylitol concentration of 37 g/l could be obtained from 50 g/l of xylose with a xylitol yield of 74% and a xylitol productivity of 0.58 g/l-hr. At 300 g/l xylose, fermentation was also carried out and then a final xylitol concentration of 242 g/l was obtained at 272 hours. It was corresponding to xylitol yield of 80.7% and xylitol productivity of 0.58 g/l-hr.

서울지역 의과대학에서의 법의부검 : 서울의대에서 과거 5년동안 실시한 부검 경험 보고

이숭덕,이정빈,이윤성 대한법의학회 2000 대한법의학회지 Vol.24 No.1

This is the statistical analysis about the medicolegal autopsy cases performed by the Department of Forensic Medicine, Seoul National University Medical College during the last 5 years. 1.The total number of cases was 330, among which male took 256(77.5%) cases, female 74(22.5%) cases. The natural death took 134(40.6%) cases, unnatural death 177(53.6%) cases. For remaining 19(5.8%) cases the cause of death was known, although thorough analyses including microscopic examination, toxicology study were done. The thirties were most as 25.4% of the total cases and the forties followed the second. 2.The number of autopsy showed severe variation annually or monthly in a year. 3.Among unnatural death, death by violent injury took 87(49.2%) cases, asphyxia 48(27.1%) cases, intoxication 17(9.6%) cases and death by thermal injuries or electric injuries 25(14.1%) cases. 4.Among natural death the abnormality in cardiovascular system were the most as 73(54.5%) cases, gastrointestinal system 38(28.4%) cases and central nervous system 12(8.9%) cases. 5.There were some differences between these and the data from other institute in the ratio of male to female, ratio of natural death to unnatural death and the ratio of specific cause of death among natural and unnatural death. 6.During this work, there were some difficulties in the aspect the irregularity of the work, in requesting toxicology and in the expense needed for the process. Considering the educational aspect for the students and the residents in pathology, performing medicolegal autopsy in medical college should be encouraged. The small number of autopsy and the closeness of the scene made the scene investigation possible in several cases, which is the ideal form that we must consider when we set up our system for the postmortem investigation.

Mo-99의 감마崩壞에 관한 硏究

朴鼎悳 建國大學校基礎科學硏究所 1988 理學論集 Vol.13 No.-

韓國에너지硏究所 同位元素室에서 製造하여 使用者에게 공급하는 Molybdenum 의 放射性 同位元素인 ??에 대하여 放出하는 감마 放射線을 檢出하고 그 에너지를 測定하여 崩壞形態를 調査하였다. 實驗은 미국 Tracor Northern 社製 model No. TN-1750, 1024 Multichannel γ-Ray Spectrometer System을 利用하여 標準 γ放射能 試料 ??의 γ-ray spectrum을 測定하여 에너지 511keV와 1275keV에 해당하는 Photopeak의 channel number 140및 314를 택하여 tow point method로 channel number대 energy의 補正式을 作成하고 이것에 의거하여 同一한 條件으로 測定한 實驗試料 ??의 γ-ray spectrum을 얻어 放出하는 γ線의 에너지를 구하였다. 이것을 標準値와 比較檢討한 結果 그 誤差가 2keV以下로 대단히 적은 優秀한 製品임이 確認되었다. In this study, the decay form of ?? which is supplied by Korea Advanced Energy Research Institude(KAERI) had been investigated from the analysis of γ-ray energy spectrum radiating from the radioactive element ??. The γ-ray energy spectrum was obtained using Nal(T1) scintillation detector and multichannel pulse height analyser. The calibration curve and formula for γ-ray energy versus channel number were made from the two photopeaks of standard radioactive source ??, 140 and 314 channel corresponding to the γ-ray energy of 511keV and 1275keV, respectively. The γ-ray energies from ?? were detected at the same condition with the standard source, and compared with standard energies of ??. Experimental results show that the γ-ray energies from the sample are in good agreement with the values of standard source within energy error of 2 keV, which means that the Mo supplied by the KAERI can be used as a standard radioactive source.

다량재해에 있어 미토콘드리아 DNA의 다형성을 이용한 개인식별 : 삼풍백화점 사건에 대하여

이숭덕,신창호,김기범,최영태,이윤성,이정빈 內務部 國立科學搜査硏究所 1996 國立 科學 搜査 硏究所 年報 Vol.28 No.-