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      • KCI등재

        論文(론문) : 大腸正格證(대장정격증)과 장누수증후군(Leaky Gut Syndrome)과의 관계 考察(고찰)

        이진철 ( Jin Cheoul Lee ),박상균 ( Sang Kyun Park ),방정균 ( Jung Kyun Bang ) 대한한의학원전학회(구 대한원전의사학회) 2013 대한한의학원전학회지 Vol.26 No.4

        A Study on the Relationship between Dae-Jang-Jung-Gyeok(大腸正格) and Leaky Gut Syndrome Lee Jin-Cheoul1·Park Sang-Kyun2·Bang Jung-kyun3 *1Dept. of Medical History, College of Korean Medicine, Kyunghee University 2Dept. of Meridian, College of Korean Medicine, Sangji University 3Dept. of Korean Medical Classics and History, College of Korean Medicine, Sangji University Objective: If the penetration ratio of the intestinal mucosa is increased, the toxic or unhealthy materials - which should not be absorbed into our bodies - will be come into our bodies. They cause a sort of anti-toxic response or confusion of the immune system, and ultimately bring various types of diseases. This syndrome is related "Poison in Excrement" or "Internal Damage(內傷發□)" and Leaky Gut Syndrome, so I will study on the relationship between them. Method: Study on the relationship between Dae-Jang-Jung-gyeok and Leaky Gut Syndrome. Result: Korean doctors in ancient times called this syndrome "Poison in Excrement" or "Internal Damage(內傷發□)" and treated it with "Dae-Jang-Jung-Gyeok(大腸正格)". Leaky Gut Syndrome is a sort of clinical lesion, which allows foreign and harmful toxins in and results in a disorder of the immune system due to the leaking intestinal mucosa. Conclusion: Based upon the analyses, Dae-Jang-Jung-Gyeok and Leaky Gut Syndrome are closely related. Therefore diseases caused by the Leaky Gut Syndrome might be expected to be cured by Dae-Jang-Jung-Gyeok. Particularly the use of treatments for self-immune diseases and allergic diseases such as atopyic dermatitis and articular rheumatism should be expected to reveal a new path of treatment for other disorders such as Leaky Gut Syndrome. Key Words: Poison in Excrement, Internal Damage(內傷發□), Dae-Jang-Jung-Gyeok(大腸正格), Leaky Gut Syndrome

      • KCI등재

        A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma

        ( Hye Jung Chang ),( Jae Hoon Lee ),( Young Rok Do ),( Sung Hwa Bae ),( Jung Lim Lee ),( Seung Hyun Nam ),( Sung Soo Yoon ),( Soo Mee Bang1 ) 대한내과학회 2011 The Korean Journal of Internal Medicine Vol.26 No.4

        Background/Aims: The clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as a firstline treatment. Because the side effects of thalidomide at a dose of ≥ 100 mg daily can be a barrier to effective treatment for these patients, we evaluated the efficacy and safety of a reduced dose of thalidomide, 50 mg, for non-transplant candidates. Methods: Twenty-one patients were treated in 4-week cycles, receiving 4 mg/m2 melphalan and 40 mg/m2 prednisone on days 1-7 and 50 mg thalidomide daily. The primary efficacy outcome was the overall response rate. Aspirin (100 mg daily) was also provided as prophylactic treatment for thromboembolism. Results: The overall response rate was 57.1%; a complete response was seen in 23.8% of patients, a partial response in 33.3%, and stable disease in 9.5%. After a median follow-up time of 16.1 months, the median time to progression was 11.4 months (95% confidence interval, 2.1 to 20.6); the median overall survival was not reached. Grades 3 and 4 adverse events included infection (10%), peripheral neuropathy (5%), diarrhea (5%), thrombosis (10%), and loss of consciousness (10%). Two patients discontinued treatment due to loss of consciousness and neuropathy. Conclusions: Low-dose thalidomide (50 mg) plus melphalan and prednisone is an effective combination drug therapy option for newly diagnosed myeloma patients who are ineligible for high-dose chemotherapy.

      • KCI등재
      • 福祉國家의 危機論과 그 含意

        方正恒 東亞大學校 大學院 1997 大學院論文集 Vol.22 No.-

        The End of The Second World War was followed by a steady increasing in social expenditures, and in the 1960s there was general confidence that the continuation and development of the welfare was assured. However, this confidence began to evaporate with the onset of economic problems stemming from the from the oil crisis of 1973. The rate of economic growth slowed down and the economy actually contracted between 1973 and 1975 as investment and profits fell and unemployment increased. In these postwar economic processes, there has been much talk about crisis in welfare states. Welfare states, it is claimed, are experiencing problems of crisis proportions arising from government overload and from fiscal and economic difficulties above mentioned. Neo-Marxists and the New Rights seem to be in agreement that capitalist state has become over-bureaucratic and that it is unresponsive to people's needs. Eventually, the argument continues, a legitimation crisis will develop as fiscal and economic problems become ever more serious and the welfare state loses public supports. There can be little doubt that government have promoted the notion of crisis as a means of justifying cuts in social expenditures, which they wish to bring about for ideological reasons. But the problems arise from a lack of political commitment to the welfare state and refusal to accept that retrenchment is not the only possible response to present difficulties. As its title indicates, this study is intended as a contribution to the continuing debate on welfare crisis in capitalist societies, and one of its purpose is to discuss and identify some of the problems involved in restructuring directions for better future welfare services and to investigate the practical alternatives for overcoming the welfare crisis. In this connection, there may be important lessons to be learned from studying the future desired state of welfare in Korea, but a different set of questions is implied.

      • 政策結果 分析의 模型과 基準에 관한 硏究

        方正恒 東亞大學校 1983 東亞論叢 Vol.20 No.2

        What is a good public policy? How may it best be implemented? The serch for answers to these questions is old as the human race. But attempts to provide more rigorous and systematic answers in the form of policy analysis are less than three decades old. These scientific efforts built on wide range of social science contribution, especially from Harold Lasswell's pioneer research of policy-oriented framework for political inquiry in 1950 to the policymaking theories of Charles Lindblom and Yehezkel Dror, and other modern investigations of policymaking. In accordance with these academic achievement, from now on, the study of the process and content of public policy hs became the major theme of political science and public administration. In its most general sense, the analysis of policy outcomes defines as activity which can contribute greatly to the understanding and improvement of policy development and implementation. However important the policy outcomes' analysis may be, until very recently it was one of the least explored of the functional activities in the policy process. As Jerry W.Lansdowne properly observed in 1968, "There has been a propensity to think in the relatively static terms of politics and administration as the totality of the policy process" Since that time, there has been growing interest in the analysis of policy outcomes among policy analysis and policy scientists. "The role of social science in government lies not in the formulation of social policy but in the measurement of its results". The above-mentioned words ol Daniel Moynihan indicate that outcomes' analysis withinpublic policy area can well be a key to progress, a platform ofr learning on which future policy can be based. The primary objective of this paper is to imake a contribution to the refinement of theories and methodologies of public policy by reexamining critically the models and criteria for the analysis of policy outcomes. In this connection, this paper concentrated all effort to explain and compare various analytical models and criteria on which evaluation can be based for the preparation of a new ground to foster systematic thinking in an emerging scientific discipline. For the sake of this objective, this paper has traced the background of problem-consciousness and the reasons why the policy outcomes' analysis is the most necessary part for recent developement in the study of public policy as an introduction. In the second chapter this paper extended a more detailed discussion on the meaning and purposes of the policy outcomes' analysis viewed as a sequential pattern of actoins. In the third chapter, this paper reviewed the characteristic features of the goal model, system model and impact for the analysis of policy outcomes concerning with the context of discovery, and represented the limitation and utility of each models. In the last two chapter, this paper, first of all, clarified the criteria i. e. effectiveness and efficiency, adequacy, equity, responsiveness, and appropriateness for the analysis of policy outcomes in connection with the contexc of validation and then dealed with the conclusion. It is my conclusion that the idea fo methodological purity may be impossible in the analysis of policy outcomes because of its political overtones, but the construction of adequate models as a simplified abstraction of real situation and relevent criteria are acute.

      • KCI등재후보
      • KCI등재

        퇴행기우울증에 관한 임상적 고찰

        방성우,이정호 大韓神經精神醫學會 1981 신경정신의학 Vol.20 No.3

        The authors studied on some clinical features of involutional depression. Subjects were 111 patients of involutional depression who visited neuropsychiatric department of In-Je Medical College Hospital, from Jan. 1975 to Dec. 1979. The results were as follows. 1. The cases of involutional depression were more frequent in female than in male.(male 24 cases, female 87 cases). The sex ratio was 1:3.6. The mean age of the subjects was 52.3±4.1 years. 2. All spouses of male patients were alive but 24 out of 84 spouses of female patients were dead. 3. At the time of the visits 78.2% of female cases was in menopausal state and the averageage of the menopause was 53 years. 4. Premorbid personality was obsessive-compulsive in 45% of the subjects. 5. The clinical symptoms were predominantly somatic than psychic in both sexes. 6. The most frequent precipitating factors in both sexes were serious physical illness and change in financial state. The common precipitating factors in male, were change in financial state, serious physical illness and change in work condition and those in female were serious physical illness, death of close family member and conflict with spouse, in that order.

      • KCI등재

        점핑활동 프로그램이 다운증후군 아동의 하지 근력 및 자세조절 전략에 미치는 영향

        정덕조,이방재,노형규 한국특수체육학회 2003 한국특수체육학회지 Vol.11 No.1

        The purpose of this study was to suggest jumping activity program for increasing the leg strength and postural control strategy and to identify the effects of jumping activity program. Participants were twelve male elementary school students with Down syndrome(exercise group: n=6, non-exercise group: n=6). The jumping activity program administrated during 8 weeks, 3 times a week, for 70 minutes at a time. The isokinetic strength variables and postural control strategy data were analyzed using t-tests(a=.05) to identify difference of means within each group. In conclusion, most of all the isokinetic strength and postural control strategy variables of participants in the exercise group were increased. Therefore, this study suggests that through the participation of jumping activity program children with Down syndrome at the age of 7~13 will stabilize their joints surrounded by muscles, increase the strength of their lower limb, and maintain the posture by increasing muscle reaction speed between lower limb and trunk.

      • Theodore J. Lowi의 政策類型論 : Theodore J. Lowi's Perspectives

        方正恒 동아대학교 부설 사회과학연구소 1986 사회과학논집 Vol.4 No.-

        No single theoretical construct has been more important to the development of public policy studies than Lowi's categorization scheme. This is because many studies about policy process have treated the policy contents as a dependent or subordinate variable, but he has criticized this process-oriented format and advocated that the policy contents must be treated as independent variables by pointing out the degree to which group activities vary the type of public policy at issue. As we know, the heart of Lowi's argument is that ''policies determine politics." He developed, in a series of articles, a typology containing distributive, regulative, redistributive, and constituent policies and argued that policy process will differ significantly depending on the policy type involved. At this point, it is important to recall J. David Greenstone's description that Lowi's pivotal work must be recognized as one of the most influential typology of public policy. The purpose of this paper is to discuss a particular analytical perspectives within policy studies which Lowi's, its formost advocate, described as the way "policies determine politics", above-mentioned. . In this connection, this paper concentrated all efforts to clarify the key characteristics of Lowi's typology of public policy and to review the basic propositions of logical structuring and the essential epistemological framework of his typology for the preparation of a new ground to refine his theoretical-bakeup. For the sake of these objectives, this paper has traced the background of problem-consciousness and the reasons why the policy typology is the most necessary part for recent development in the study of public policy as an introduction in chapter I. And then, this paper Entended a more detailed discussion on the Lowi's analytical perspectives and the logical structure of his typology. In chapter Ⅲ and Ⅳ, this paper reviewed in depth the characteristic features of Lowi's classification and its relations with the policy process. In spite of much criticism are directed Lowi's methodological apparatus and epistemological framework, at the moment this is only a hope for the future. But if "policies determine politics" is to become anything more than one of slogans which already abound in the policy sciences, this is the way we will have to go.

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