가성 종양으로 보인 신경베체트병 -임상 및 병리적 연관 비교-

박운규,김승현,김주한,김명호 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

예비유아교사들이 인식한 좋은 유아교사의 특성

조운주 忠州大學校 2007 한국교통대학교 논문집 Vol.42 No.-

The purpose of this study was to understand the characteristics of good early childhood teacher that preservice teachers thought. The subjects of this study were 232 preservice teachers. We used open questionnaire, and analyzed qualitatively the meanings. In this research, the participants thought the good early childhood teacher as a mother who cares for with love, a true friend of children, an intellectual teacher who has practical knowledge, a person who can control emotion and have good personality model, and a person with faith and passion. Preceding researches have had fixed images of early childhood teacher as a person who has good personality and professional knowledge and skill. But this study pointed out more various characteristics of good early childhood teacher.

紫式部硏究 : 『紫式部日記』に描かれている批判意識を中心として

金昌柱,姜雲景 公州大學校 資源科學硏究所 1998 資源科學硏究論文集 Vol.6 No.-

Heian Dynasty era was the palmy days of women's literature. Murasakisikibu wrote "Genzimonogatari". She served at court under the queen Syoushi. I studied "Murasakisikibu's Diary". That was especially about Murasakisikibu's talent as an author of "Genzimonogatari". I found Murasakisikibu's critical thought. That was the basis of "Genzimonogatari".

정상과 만성염증성 활막배양세포에서 Corticotropin releasing hormone(CRH)이 cyclooxygenaase-1(COX-1)과 cyclooxygenase-2(COX-2) mRNA발현에 미치는 영향

정운원,이승관,이창규,조경진,김성욱,하주희,서장훈 高麗大學校 倂設 保健大學 保健科學硏究所 2000 保健科學論集 Vol.26 No.1

Corticotropin-releasing hormone(CRH) is a major regulator of the hypothalamic-pituitaryadrenal axis(HPA). In inflammatory stress, the cytokines TNF-, IL-6 stimulate the production of CRH, a 41 amino acids neuropeptide, in the hypothalamus. The release of CRH leads to pituitary production of adrenocorticotropic hormone, followed by glucocorticoid secretion by the adrenal cortex. Glucocorticoids suppress namy components of the inflammatory process. Recently, CRH and CRH receptor were reported to be located in the periphery such as Immune system and chronic inflammatory sites as rheumatoid arthritis (RA). Cyclooxygenase consisted of two isoforms, COX-1 and COX-2, converts arachdonate to prostaglandins(PGs) which are important mediators of inflammation. insymoviocyte in RA, it was described that COX-2 mRNA was markedly increased by inflammatory agents, PMA or IL-1 and COX-1 transcripts were not modulated. We examined the modulation of COX by immune CRH in cultured normal and rheumatoid synoviocytes. Our results were shown that COX-1 mRNA expression decreased with the each stimulation of PMA and IL-1 in normal synoviocyte. In RA synoviocyte, PMA and IL-1 were increased mRNA expression of COX-1. In simultaneous treatment with CRH, PMA group was decreased, but IL-1 group was increased mRNA expression of COX-1. COX-2 mRNA expression was slightly increased by the treatment with PMA and highly increased by IL-1. After CRH treatment, PMA and IL-1 addictively increased COX-2 mRNA expression. We think that these results are contributed to the influence of increased cANP by CRH on the promoter of COX-2 in normal and synoviocytes. Because many cytokines, neuropeptides, and signal transduction pathways are involved in chronic inflammation, the exact role of CRH on inflammation is not fully elucidated. To achieve this goal, further experiments are needed.

용매침윤 수지에 의한 중금속 회수에 관한 연구

李大云,李垣,金珠姬,李承頀 연세대학교 대학원 1981 延世論叢 Vol.18 No.1

The application of the solvent-impregnated resin(SIR), 5,7-dibromo-8-hydroxyquinoline(DBQ)-impregnated polyurethane foam, to the selective recovery of some heavy metal ions from aqueous solution was investigated. The adsorption behavior of DBQ on polyurethane foam was studied to determine the optimum conditions for preparing the SIR. It was found that SIR impregnated with DBQ had adsorption capacity about 5×10-2 mmol M(II) per gram foam. The conditions for recovery and readsorption of metal ions were determined.

도재표면 처리제가 복합레진과 도재와의 결합에 미치는 영향

백명주,박주미,배태성,박찬운 全北大學校 齒醫學硏究所 1991 전북치대논문집 Vol.9 No.1

This study investigated the effect of porcelain primer on bonding of composite resin to porcelain surface. In order to test the bond strength between porcelain and composite resin, porcelain cylinders were embedded in acrylic resin, and polished with 240grit silicone carbide paper. The specimens were divided into twelve groups. All specimens were treated with three porcelain primers and bonded with five composite resins. All test groups were stored in 37℃ distilled water for 48hours. Shear bond strengths were measured with Instron(Model 4201) at a cross-head speed of 1㎜/min. The obtained results were as follows : 1. Scotchprime/SiluxⅡ group and BISCO Porcelain Primer/Bisfill group showed significant higher bond strengths than Clearfil Porcelain Primer/Photo clearfil Bright group(p<0.05). And there was no significant differences in bond strengths between Scotchprime/SiluxⅡ group and BISCO Primer/Bisfill group(p>0.05). 2. When composite resins were used with Scotchprime, the bond strengths were decresed SiluxⅡ(16.68±3.35 MPa), Bisfil(16.23±4.54 MPa), Poly-Fill(14.74±4.08 MPa), Photo Clearfil Bright(13.75±2.89 MPa) and Pekalux(14.74±4.08 MPa) in order, but there was no statistical significance(p>0.05). 3. When composite resins were used with BISCO Porcelain Primer, the bond strength were decreased Bisfil(16.17±1.60 MPa), SiluxⅡ(12.13±2.37 MPa), Poly-Fill(10.78±1.99 MPa), Photo Clearfil Bright(9.91±4.59 MPa) and Pekalux(7.36±2.16 MPa) in order, but there was no statistical significance(p>0.05). 4. SiluxⅡ, Photo Clearfil Bright and Poly-Fill used with Scotchprime showed significant higher bond strengths than BISCO Porcelain Primer(p<0.05).

딸기의 농약잔류량 세척효과

김운주, 박광순 충북대학교 생활과학대학 생활과학연구소 1996 생활과학연구 Vol.3 No.

-본문참고-

EFFECT OF EUGENOL AND CAPSAICIN ON THE VOLTAGE-DEPENDENT ION CHANNELS OF TRIGEMINAL AFFERENTS

김주연,박상진,최기운,최호영 대한치과보존학회 2000 Restorative Dentistry & Endodontics Vol.25 No.3

삼차신경절의 뉴런이 구강악안면영역에서의 촉각, 압각,온도각 및 통각 등 다양한 감각을 중추신경계로 전달하는 역할을 하는 것은 주지의 사실이다. 이러한 신경전달에 있어서 이온통로는 감각정보를 전달하는데 핵심적인 역할을 수행하며 특히 소디움 통로는 활동전위의 발생에 중요하다. 소디움 통로는 tetrodotoxin-sensitive(TTX-5) 및 tetrodotox-in-resistant(TTX-r) 통로로 나누어지는 데 이 중 TTX-r 통로에 발생되는 tetrodotoxin-resistant sodium cur-rent(TTX-r INa.)는 capsaicin에 민감한 일차구심신경세포에서 유해자극에 의해 통각신호를 발생시키고 전달하는데 중요하다. 또한 칼슘 통로는 시냅스 전토에 있어서 필수적인 역할을 수행하고 있다. 한편 치과영역에서 치수의 진정 목적으로 eugenol이 흔히 사용되고 있다. 그러나eugenol의 그 작용 기전에 대해서 현재까지 이온통로에 대한 상세한 결과가 없는 실정이며 최근의 보고에 의하면 eugenol이 capsaicin수용기를 통하여 감각신경에 대한 억제작용을 나타낸다고 한다. 따라서 본 실험은 eugenol과 capsaicin이 흰쥐의 삼차신경절의 TTX-r INa와 칼슘통로에 어떠한 영향을 미치는지를 알아보고 eugenol이 capsaicin 수용기를 통하여 작용하는지를 검증하고자 시행되었다 삼차신경절 뉴런은 100-150g의 흰쥐의 삼차신경절로부터 외과적으로 절제하여 통법의 화학적 및 기계적 처리를 통해 단일세포로 분리하였고 이를 Whole-cell patch clamp 방법을 이용하여 시행한 바 다음과 같은 결론을 얻었다. 1.1mM의 dugenol은 흰쥐 삼차신경절 뉴런의 TTX-r INa.와 HVA INa.를 억제하였다. 2.1㎛의 capsaicin은 흰쥐 삼차신경절 뉴런의 TTX-r INa 와 HVA INa 를 억제하였다 3.Capsazepine은 capsaicin의 HVA ICa 에 대한 억제작용을 차단하였다. 4.Capsazepine은 capsaicin의 HVA ICa .에 대한 억제작용을 차단하지 못하였다. 결론적 으로 eugenol과 capsaicin은 tetrodotoxin-resistant sodium current(TTX-r INa )와 high voltage-activated calcium current(HVA ICa )를 모두 억제하는 것으로 나타났으며 , 이러한 작용이 통각의 발생과 시냅스 전달과정을 차단하여 치수 진정 목적으로 많이 사용하는 eugenol의 작용기전으로 판단된다. 한편 capsaicin의 길항제인 capsazepine을 전처치하였을 때에도 eugenol의 HVA ICa 에 대한 억제효과는 변화가 없었다. 이와같은 결과로 보아 HVA ICa 에 관한한 eugenol은 capsaicin 수용기를 통하여 나타나지 않는 것으로 사료된다.

저장안정성이 개선된 천연장 소시지의 제조를 위한 감마선 조사

이주운,조철훈,변명우 경산대학교 생명자원개발연구소 2001 생명자원과 산업 Vol.5 No.-

Quality properties in the sausage stuffed into the irradiated natural lamb and pork intestine for manufacturing the high quality emulsion-type meat produces were studied. The microbial changes of irradiated casings and the microbial growth of the sausages with gamma-irradiated natural casings were observed. Population of Total aerobia bacteria was decreased by gamma irradiation, dependent upon the irradiation dose. The number of microflora in lamb and pork casings was reduced by about 5.5 log cycle at 5kGy. Population of total aerobic bactelia of sausages stuffed in non-irradiated lamb and pork casing was about 3.6 log cfu/g after just manufacture and was about 7 log after 10 day storage. However, population of total aerobic bacteria of sausages with 3 key-irradiated and 5 kGy-irradiated casings was 2.48 and 0.32 log in lamb, and 2.78 and 0.60 log in pork respectively. The sausages vacuum-packaged and stored were shown no chance in the 2-thiobarbituric acid reactive substances value during storage. Irradiated sausage showed the higher TBARS value than that of nonirradiatd control at 5-day with pork casing and at 10day with lamb casing. Shear force of the sausages were decreased in both irradiated casings but the sensory evaluation showed no difference. Therefore, the gamma irradiation was a useful tool to sanitize the natural pork and lamb casings and extend the shelf-life of the high quality, value-added sausage made with those casings.

충북지역 주부의 식품 위생 지식 및 행동 평가

김운주,최은희 충북대학교 교육 ·생활연구소 생활과학연구센터 2002 생활과학연구논총 Vol.5 No.-

The purpose of this study was to evaluate food safety knowledge and behaviors of housewives in Chungbuk province areas; and examine relationships between knowledge and behaviors. Results of this study showed respondents reported a satisfactory level of food safety knowledge(correct rate 78.5%). Respondents were most knowledgeable about 'food production & holding(80.5%)' and least konwledgeable about 'food poisoning(75.4%)'. The performance of food safety behaviors were not satisfactory(3.3). There were areas for improvement on 'I use different chopsticks to eating food, instead of using the cooking chopsticks'. 'I sanitize the cutting board daily.' 'I wash my hands with soap after cracking eggs.' 'I don't use hands to tasting sample foods'. 'I use different knives for meats and vegetables', 'I use different cutting boards by food'. 'I don't issue frozen item before cooking', 'I don't refreeze thawed food'. The Pearson correlations were calcuated between food safety knowledge and behaviors. A weak statisticallysignificant relationship was found between the two variables(r=0.285, p<0.01). The major source of food safety information was TV·radio (50.4%). Respondents' perception rate of HACCP symbol was 22.0%.