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Josué Aliaga Ramos,Yoshinori Morita,Takashi Toyonaga,Danilo Carvalho,Moises Salgado Pedrosa,Vitor N. Arantes 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.5
Background/Aims: Endoscopic submucosal dissection (ESD) is currently considered the first-line treatment for the eradication of superficialneoplasms of the esophagus in Eastern countries. However, in the West, particularly in Latin America, the experience withesophageal ESD is still limited because of the high technical complexity required for its execution. This study aimed to present the resultsof the clinical application of ESD to manage superficial esophageal neoplasms in a Latin American center in over 100 consecutivecases. Methods: This retrospective study included consecutive patients who underwent endoscopic ESD for superficial esophageal neoplasmsbetween 2009 and 2022. The following clinical outcomes were assessed: en bloc, complete, and curative resection rates, local recurrence,adverse events, and procedure-related mortality. Results: Esophageal ESD was performed mainly for squamous cell carcinoma (66.6%), high-grade intraepithelial neoplasia (17.1%),and adenocarcinoma (11.4%). En bloc and complete resection rates were 96.2% and 81.0%, respectively. The curative resection rate was64.8%. Adverse events occurred in six cases (5.7%). Endoscopic follow-up was performed for an average period of 29.7 months. Conclusions: ESD performed by trained operators is feasible, safe, and clinically effective for managing superficial neoplastic lesions ofthe esophagus in Latin America.
Félix Téllez-Ávila,Josué Barahona-Garrido,Sandra García-Osogobio,Gustavo López-Arce,Jesús Camacho-Escobedo,Angela Saúl,Salvador Herrera-Gómez,Javier Elizondo-Rivera,Rafael Barreto-Zúñiga 대한소화기내시경학회 2014 Clinical Endoscopy Vol.47 No.1
Background/Aims: No clear data have been established and validated regarding whether rectal retroflexion has an important and therapeutic impact. The aim of the present study was to evaluate the diagnostic yield and therapeutic impact of rectal retroflexion compared with straight view examination. Methods: A prospective single-blind study was conducted. Consecutive patients evaluated between October 2011 and April 2012 were included. Results: A total of 934 patients (542 women [58%]) were included. The mean age was 57.4±14.8 years. Retroflexion was successful in 917 patients (98.2%). Distinct lesions in the anorectal area were detected in 32 patients (3.4%), of which 10 (1%) were identified only on retroflex view and 22 (2.4%) on both straight and retroflex views. Of the 32 identified lesions, 16 (50%) were polyps, nine (28.1%) were angiodysplasias, six (18.8%) were ulcers, and one (3.1%) was a flat lesion. All 10 patients (1%) in whom lesions were detected only by rectal retroflexion showed a therapeutic impact. Conclusions: Rectal retroflexion has minimal diagnostic yield and therapeutic impact. However, its low rate of major complications and the possibility of detecting lesions undetectable by straight viewing justify its use.
Alejandra Pérez-Nava,Josué D. Mota-Morales,Zaira Y. García-Carvajal,Sara E. Herrera-Rodríguez,Gerardo Arrevillaga-Boni,Cristy L. Azanza-Ricardo,Milton O. Vazquez-Lepe,J. Betzabe Gonzalez-Campos 한국섬유공학회 2018 Fibers and polymers Vol.19 No.1
Silver and gold nanoparticles were produced and embedded in poly(vinyl alcohol) (PVA) and chitosan (CTS) solutions by the photoreduction of metallic salt precursors triggered by direct sunlight irradiation, in which the polymers acted as reducing, dispersing and stabilizing agents. Sunlight photoreduction can be standardized using a constant UV index regardless of the season. This strategy was found to be an improvement over other common energy sources used to trigger the reduction of metal ions, including UV light irradiation and high-temperature reduction with mechanical stirring. The resulting PVA/metal nanoparticle and CTS/metal nanoparticle composite solutions were processed into thin films and nanofiber composites. In vitro testing of the cytotoxicity and biocompatibility demonstrates that the film composites are non-toxic andbiocompatible with the HT-29 human colon cancer cell line. Promotion of HT-29 cell growth using our hybrid composites was observed, in contrast to other studies in which colloidal NPs were tested. Therefore, a sustainable approach for the onestep preparation of biocompatible polymer/metallic nanoparticle composites is reported.
Romero-Arenas Omar,Amaro-Leal Luis Josué,Rivera Antonio,Parraguirre-Lezama Conrado,Sánchez-Morales Primo,Villa-Ruano Nemesio 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.3
This investigation reports on the biological control of Sphenarium purpurascens by using different concentrations of conidia from a native strain of Beauveria bassiana (MABb1) isolated in Puebla, Mexico under laboratory and in situ conditions. Formulations containing this native strain combined with two mesoporous materials (diatomaceous earth “D” and zeolite “Z”) were assayed in order to determine their effect on the mortality of the grasshopper. Concentrations of 3.67 × 108 to 10.30 × 108 conidia mL−1 caused a substantial mortality rate in the fourth-instar nymphs and adults of S. purpurascens. The observed mortality was directly proportional to the concentration of conidia. Under controlled conditions, the highest specific death rate K(d−1) was 0.78 for the formulation containing Z + D + MABb1 at 72 h post-infection. The formulations of D + MABb1 and Z + D + MABb1 caused a noticeable decrease in the population of grasshoppers in the experimental plots with statistical significant differences (α < 0.05). Interestingly, an increase in the mortality of S purpurascens occurred in July, August and September 2017 when the highest incidence of the grasshopper was recorded. Remarkably, the treatment based on Z + D + MABb1, produced an improvement in the yields of experimental maize plots (7847.4 ± 0.70 Kg ha−1) in comparison to control plots (4453.9 ± 0.50 Kg ha−1). These favorable consequences are reported for the first time in corn crops from Mexico.
Enrique Coss-Adame,Janette Furuzawa-Carballeda,Andric C Perez-Ortiz,Ana López-Ruiz,Miguel A Valdovinos,Josué Sánchez-Gómez,José Peralta-Figueroa,Héctor Olvera-Prado,Fidel López-Verdugo,Sofía Narváez-C 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.4
Background/AimsThe evidence suggests that a shorter esophageal length (EL) in gastroesophageal reflux disease (GERD) patients is associated with the presence of hiatal hernia (HH). However, there are no reports of this association in patients with achalasia. The aim is to (1) determine the prevalence of hiatal hernia in achalasia patients, (2) compare achalasia EL with GERD patients and healthy volunteers (HV), (3) measure achalasia manometric esophageal length to height (MELH) ratio, and (4) determine if there are differences in symptoms between patients with and without hiatal hernia. MethodsThis retrospective and cross-sectional study consist of 87 pre-surgical achalasia patients, 22 GERD patients, and 30 HV. High-resolution manometry (HRM), barium swallow, and upper endoscopy were performed to diagnose HH. The EL and MELH ratio were measured by HRM. Symptoms were assessed with Eckardt, Eating Assessment Tool, and GERD–health-related quality of life questionnaires. ResultsThe HH in GERD’s prevalence was 73% vs 3% in achalasia patients (P < 0.001). Achalasia patients had a longer esophagus and a higher MELH ratio than HV and GERD patients (P < 0.001). GERD patients had a lower MELH ratio than HV (P < 0.05). EAT-10 (P < 0.0001) and Eckardt (P < 0.05) scores were higher in achalasia without HH vs HH. ConclusionsThe prevalence of HH in achalasia is significantly lower than in GERD. The longer EL and the higher MELH ratio in achalasia could explain the lower prevalence of HH. Despite the low prevalence of HH in achalasia patients, the surgeon should be encouraged not to rule out HH since the risk of postoperative reflux may increase if this condition is not identified and corrected.
Discovering Users-Centric Hierarchical Process Models in Social Networking Services
Josue Obregon,Jae-Yoon Jung(정재윤) 대한산업공학회 2014 대한산업공학회 추계학술대회논문집 Vol.2014 No.11
Social network analysis has been an interest topic among researchers since the middle of the last century because it helps to understand social behaviors based on the interactions among people. Moreover, at the beginning of 2000’s, online social networking services such as Facebook and Twitter have emerged rapidly and have become very huge data sources for social media analysis. A few studies related to processes that occur on a social network have been published, focused on topics like information diffusion and more precisely modeling diffusion process. On the other hand, process mining is an emergent discipline that combines process modeling and analysis with data mining techniques and offers insights over business process data stored in the so-called event logs, recorded everyday by information systems. Those event logs are the starting point of one process mining type known as process discovery, in which a process model is discovered based only on the data extracted from an event log file. In this paper a novel approach is presented, in which online social network data is used for process mining to discover hierarchical process models. The data first is preprocessed by means of community detection techniques in order to reduce its complexity, and an extended Heuristics Miner is then applied to the discovered communities to give insights about information diffusion process on the network. An experiment with real world Facebook data is conducted and its results are evaluated and discussed.
Age of Information in a Decentralized Network of Parallel Queues with Routing and Packets Losses
Josu Doncel,Mohamad Assaad 한국통신학회 2022 Journal of communications and networks Vol.24 No.1
The paper deals with age of information (AoI)in a network of multiple sources and parallel queues withbuffering capabilities, preemption in service and losses in servedpackets. The queues do not communicate between each other andthe packets are dispatched through the queues according to apredefined probabilistic routing. By making use of the stochastichybrid system (SHS) method, we provide a derivation of theaverage AoI of a system of two parallel queues (with and withoutbuffer capabilities) and compare the results with those of a singlequeue. We show that known results of packets delay in QueuingTheory do not hold for the AoI. Unfortunately, the complexityof computing the average AoI using the SHS method increaseshighly with the number of queues. We therefore provide an upperbound of the average AoI in a system of an arbitrary number ofM/M/1/(N+1)* queues and show its tightness in various regimes. This upper bound allows providing a tight approximation of theaverage AoI with a very low complexity. We then provide agame framework that allows each source to determine its bestprobabilistic routing decision. By using Mean Field Games, weprovide an analysis of the routing game framework, propose anefficient iterative method to find the routing decision of eachsource and prove its convergence to the desired equilibrium.