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주의력결핍 과잉행동장애 남아의 증상과 부모의 주의력결핍 과잉행동 증상 및 인격 양상과의 관련성
신승우(Woo-Seung Shin),최혜라(Hye-Ra Choi),김건우(Kynwoo Kim),이중선(Joong-Sun Lee),박수빈(Subin Park),홍진표(Jin Pyo Hong),유한익(Hanik K. Yoo) 대한소아청소년정신의학회 2009 소아청소년정신의학 Vol.20 No.1
Objectives : This study was conducted to investigate the association between the symptoms of boys with attention-deficit hyperactivity disorder (ADHD) and the attention-deficit hyperactivity symptoms, temperament and character patterns of their parents. Methods : Forty-five boys with ADHD and who met the DSM-IV criteria were evaluated by using the ADHD rating scale (ADHD-RS), and their parents completed the Korean Adult ADHD scale (K-AADHDS) and the Temperament and Character Inventory (TCI). Results : The parental K-AADHDS scores were not associated with the ADHD-RS total score and the subscale scores of their siblings. The most potent variable related to the ADHD-RS total score was the maternal self-directedness, and the second was the maternal persistence. The maternal self-directedness was the variable that was most correlated with the hyperactivity/impulsivity subscale scores of the ADHD-RS. Conclusion : The results suggest that the paternal ADHD symptoms may not be related to the ADHD symptoms of boys with ADHD. Higher maternal self-directedness and persistence may decrease overall the ADHD symptoms of these boys, and higher maternal self-directedness itself may predict lower hyperactivity/impulsivity symptoms of the boys with ADHD.
하시모토갑상선염에 동반된 골수를 침범한 ( 병기 4E 기 ) 원발성 갑상선 림프종 1 예
이기업,송영기,박중열,김기수,김상희,공경엽,조재근,추윤호,엄완식,지현숙 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.4
Primary lymphoma of the thyroid is a relatively rare malignant tumor of the thyroid. It is known to be frequently associated with Hashimoto's thyroiditis. In Korea, a few cases of primary lymphoma of the thyroid have been reported and most of these cases were in the stage I E or II E. Recently, we experienced a case of the primary thyroid lymphoma, stage IV E associated with Hashimoto's thyroiditis in a 70-year-old woman who presented with dysphagia and dyspnea due to rapidly enlarging neck mass. She was treated with combination chemotherapy(cyclophosphamide, adriamycin, vincristine and methylprednisolone) and local radiotherapy and achieved partial response with resolution of dysphagia and dyspnea(J Kor Soc Endocrinol 9: 390-394, 1994).
박정식,이기업,조유숙,송영기,김상욱,박중열,김기수,조구영 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.1
Chronic hypophosphatemia caused by decreased intestinal absorption or increased renal clearance, may lead to rickets or osteomalacia independently of other predisposing abnormalities. The conditions commonly associated with increased renal clearance of phosphate are X-linked hypophosphatemic rickets, tumor associated rickets/osteomalacia, RTA and Fanconi syndrome. Recently we experienced 3 men with adult-onset, histologically proven osteomalacia associated with increased renal clearance of phosphate. None of them had a family history of bone disease, tumors or other tubular defects. All of these had remarkable biochemical and clinical improvement with medical treatment such as 1, 25-dihydroxyvitamin D and phosphate supplementation. Although we did not find tumors yet, we could not rule out the possibility of tumor-associated osteomalcia since it often takes several years to make a diagnosis because of small size, benign nature and unusual location of tumors. Thus, careful long-term follow up for tumor occurrence will be maintained in these patients with sporadic nonfamilial hypophosphatemic osteomalacia(J Kor Soc Endocrinol 9:25-31, 1994).
이문호,이정교,이기업,송영기,박중열,김기수,조원경,최기영 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.2
Primary carcinoma of the pituitary is only rarely reported. About half of the reported cases are nonfunctional. It is generally agreed that the presence of distant metastasis is required to clearly establish the diagnosis of pituitary carcinoma. We have experienced a case of ACTH-producing pituitary carcinoma causing Cushing's syndrome which could be diagnosed by histologic features only without evidence of distant metastasis. A 35-year-old female with Cushingoid appearance was diagnosed as Cushing's disease after biochemical and neuroradiological evaluation. Near total removal of the pituitary tumor was performed. By histopathologic examination, the tumor revealed evidences of histological malignancy such as prominent nuclear pleomorphism, frequent mitoses and extensive tumor necrosis. Pseudosarcomatous components were also noted. By immunohistochemical studies, the tumor cells expressed ACTH. However, there was no evidence of distant metastasis at the initial operation. She was diagnosed as having ACTH producing pituitary carcinoma by histologic feature only. One month later, she complained progressive nausea and vomiting, and follow-up brain MRI revealed regrowing pituitary mass. She was reoperated and near total tumor bulk was removed again followed by radiotherapy with 5580 rads. Four month after the second operation, she developed generalized tonic clonic seizure. Brain CT showed multiple enhancing nodules on left temporal and frontal lobes, and around falx cerebri. She refused further treatment and was managed only with anticonvalsants. About month after discharge she died at home(J Kor Soc Endocrinol 9:136-140, 1994).
이정신,최승원,이기업,김상욱,박중열,김기수 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.3
A few studies strongly suggest that pernicious anemia is a risk factor for osteoporosis, but the mechanism is unknown. Recently we experienced a 65-year-old female with pernicious anemia and osteoporosis. She had multiple compression fractrues of thoracolumbar vertebrae and low bone mineral density of spine and femur by dual photon absorptiometry. Pernicious anemia was confirmed with low serum vitamin B12 level and characteristic bone marrow findings. She did not have other secondary causes of ostoeporosis other than pernicious anemia. Although we co not believe pernicous anemia is solely responsible for osteoporosis of this patient, it must have contributed some to the development of the disease. In summary; pernicious anemia is a risk factor for osteoporosis and optimal evaluation and management of bone loss should be done in patients with pernicious anemia, especially in postmenopausal state(J Kor Soc Endocrinol 8:351~355, 1993).