치과용 디지털 색상 분석용 기기의 정확성과 재현 능력에 대한 평가

정중재,박수정,조현구,황윤찬,오원만,황인남 大韓齒科保存學會 2008 Restorative Dentistry & Endodontics Vol.33 No.4

본 연구에서는 치과용 디지털 색상 분석기기 중 하나인 ShadeScan (CYNOVAD, Montreal, Canada)의 색상 분석의 정확성과 재현 능력을 평가하였다. 균일한 치아 배열을 가진 20대 성인 남자 8명과 여자 8명의 상악 인상을 고무인 상제 (Exaflex, GC, Japan)를 이용하여 채득하고, 인상에 A2 색상의 임시 크라운 제작용 자가중합형 레진을 주입하여 치아 모델을 완성하고, ShadeScan을 이용해 각 치아의 영상을 얻어 컴퓨터의 ShadeScan 프로그램으로 분석하였다. 그리고 측정 결과의 재현 능력를 평가하기 위해 2개의 치아 모델을 임의로 선택하여 각 치아마다 10회의 색상 측정을 시행하여 분석 결과를 비교하였다. 또한 분석된 영상의 동일 shade 간의 색차를 확인하기 위해 광중합 복합레진인 Gradia Direct (GC, Tokyo, Japan)와 shade guide의 CIE L^(*)a^(*)b^(*) 값을 백색과 흑색 배경판 상에서 spectrophotometer (Spectrolino, GretagMacbeth, USA)로 측정하고, ShadeScan에 의해 동일한 shade로 분석된 shade guide간의 색차를 계산하여 다음의 결과를 얻었다. 모든 치아에서 모델 제작 재료와 동일한 A2 색상므로 분석된 경우는 없었으며, 개개의 치아에서 전체 순면이 동일한 색상으로 분석된 예는 없었다. 또한 동일한 치아군에서 치아의 크기 , 형태 , 순면의 굴곡 등에 따라 서로 다른 색상 분포를 보였다. 재현성 평가에서 각 치아의 중앙부는 비교적 일정한 재현성출 보였으나, 절단부와 주변 부위는 재현성이 낮았으며, 동일한 shade로 분석된 shade guide 간에는 3 이상의 색차 (ΔE^(*))를 보였다. 이상의 결과는 치과용 디지털 색상 분석기기는 비록 높은 재현 능력은 가지고 있지만 정확성에 오류가 있음을 시사하며 , 따라서 이러한 기기를 이용한 색상 분석 시 좀 더 세밀한 주의와 다른 방법의 추가 사용이 필요하리라 사료된다. This study was done to evaluate the reliability of the digital color analysis system (ShadeScan, CYNOVAD, Montreal, Canada) for dentistry. Sixteen tooth models were made by injecting the A2 shade chemical cured resin for temporary crown into the impression acquired from 16 adults. Surfaces of the model teeth were polished with resin polishing cloth. The window of the ShadeScan handpiece was placed on the labial surface of tooth and tooth images were captured, and each tooth shade was analyzed with the ShadeScan software. Captured images were selected in groups, and compared one another. Two models were selected to evaluate repeatability of ShadeScan, and shade analysis was performed 10 times for each tooth. And, to ascertain the color difference of same shade code analyzed by ShadeScan, CIE L^(*)a^(*)b^(*)values of shade guide of Gradia Direct (GC, Tokyo, Japan) were measured on the white and black background using the Spectrolino (GretagMacbeth, USA), and Shade map of each shade guide was captured using the ShadeScan. There were no teeth that were analyzed as A2 shade and unique shade. And shade mapping analyses of the same tooth revealed similar shade and distribution except incisal third. Color difference (ΔE^(*)) among the Shade map which analyzed as same shade by ShadeScan were above 3. Within the limits of this study, digital color analysis instrument for dentistry has relatively high repeatability, but has controversial in accuracy.

전형적 징후를 동반한 결절성 경화증 1례

강순구,이중화,설종구 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

We report a case of tuberous sclerosis accompying the typical stigmata in a 18-year-old women who had undergone right nephrectomy. 40 to 80 per cent of tuberous sclerosis patients have renal angiomyolipoma. When angiomyolipoma is associated with tuberous sclerosis, the renal tumors usually are bilateral, muliple, samll and asymptomatic. Currently, it should be possible to make the diagnosis of angiomyoliporna in most cases on the basis of the combined imaging characteristics of CT and ultrasongraphy. Lesions associated with tuberous sclerosis require surgical intervention only when they become symptomatic or enlarge silently.

비외상성 두개내 출혈 환자에서 심근손상의 발생과 예후에 미치는 영향

강구현,황성호,이강현,조준휘,김성환,문중범,박해상,이서영,이성수,김헌주 대한응급의학회 2000 대한응급의학회지 Vol.11 No.4

Objective: The aim of this study was to investigate the clinical significance of myocardial injuries in patients with nontraumatic intracranial hemorrhage by identifying the occurrence of myocardial injury and defining its correlation with subsequent cardiovascular events. Subjects and methods: One hundred twenty-four patients with nontraumatic intracraninal hemorrhage presented to the emergency department within six hours from onset of symptoms were enrolled. Brain CT, serial electrocardiography, and echocardiography were done at the emergency center. Blood samples for troponin I and creatine kinase(CK)-MB were drawn immediately and eight hours after admission, Troponin I and CK-MB were measured using a chemiluminescent immunoassay, respectively. Results: Electrocardiographic and echocardiography abnormalities were found in 65 cases(52.4%) and 21 cases(17%), respectively. Serum troponin I and creative kinase-MB were increased in 35 cases (28.2%) and in 58 cases(46.8%), respectively. Abnormal findings of echocardiography and ECG, as well as elevated levels of serum troponin I and creative kinase-MB, were associated with an increased risk of cardiovascular event and survival. Logistic regression analysis revealed that an abnormal echcocardiographic finding and elevation of serum troponin I were factors associated with the occurrence an adverse cardiovascular event and that electrocardiographic abnormalities and initial mental status were factors associated with poor prognosis. Conclusion: This study reveals that actual myocardial injury develops in a significant proportion of patients with nontraumatic intracranial hemorrhage and that the development of the myocardial injury is associated with an adverse cardiovascular event that occurs during admission.

국내산 잣나무와 낙엽송의 재질

권성민,황원중,권구중,김남훈 江原大學校 森林科學硏究所 2004 Journal of Forest Science Vol.20 No.-

국산 잣나무와 낙엽송의 비중, 연륜폭, 만재율, 종압축강도, 횡압축강도 및 전단강도를 측정하고 방사 ?향의 병이를 조사하여 다음의 결과를 얻었다. 1) 비중은 잣나무가 0.48로 낙엽송의 0.88보다 약 2배정도 낮은 값을 보였다. 두 수종 모두 수심에서 낮은 값을 보여주고 그 후 약 15연륜 까지 다소 증가하다가 일정해지는 경향을 보여주었다. 2) 연륜폭은 잣나무 3.43㎜, 낙엽송 2.83㎜로 잣나무가 낙엽송에 비해 넓었으며, 만재율은 잣나무 30%, 낙엽송 47%로 낙엽송이 잣나무에 비해 높았다. 두 수종 모두 만재율이 커짐에 따라 비중은 커지는 경향을 나타냈다. 3) 종압축강도와 종압축 비례한도, 종압축 영계수는 잣나무가 각각 300kgf/㎠, 270kgf/㎠, 9.2×10³kgf/㎠로서 낙엽송의 600kgf/㎠, 550kgf/㎠, 20×10³kgf/㎠에 비해 모두 낮은 수치를 나타내었다. 종압축강도, 종압축 비례한도 및 영계수의 방사방향변이는 두 수종 모두 뚜렷한 경향을 보이지 않았다. 4) 방사단면의 전단강도는 잣나무가 51kgf/㎠, 낙엽송이 69kgf/㎠으로 낙엽송이 컸으며, 접선단면은 잣나무가 56kgf/㎠, 낙엽송이 86kgf/㎠으로 낙엽송이 큰 값을 나타내었다. Density, annual ring width, latewood percentage and compressive properties of Pinus koraiensis and Larix kaempferi grown in Research Forest of Kangwon National University were measured and their radial variations were investigated. Density(Wa/Va) of Pinus koraiensis and Larix kaempferi was 0.48g/cm² and 0.88g/cm², respectively. Density of both species was slightly lower at pith area, increased gradually with cambial age up to about 15 years and then became constant. Annual ring width of both species was 3.43㎜ and 2.83㎜, respectively. Annual ring width of both species was irregular at pith area but regular after about 20 years. Latewood percentage of both species was 30% and 47%, respectively. Latewood percentage of Pinus koraiensis and Larix kaempferi increased with cambial age up to 14 years and 10 years, respectively and then became constant. Compressive strength, proportional limit and Young's modulus parallel to the grain of Pinus koraiensis were 330 kgf/cm², 270 kgf/cm² and 9.2×10³ kgf/cm², and those of Larix kaempferi were 600 kgf/cm², 550 kgf/cm² and 20×10³ kgf/cm², respectively. Shearing strength in radial direction of Pinus koraiensis and Larix kaempferi was 51 kgf/cm² and 69 kgf/cm², and that of tangential direction was 56 kgf/cm² and 86 kgf/cm², respectively. In this study, compressive and shearing properties of both species did not show any significant differences between juvenile wood and adult wood. Both species showed significant differences in the measured values.

산불 피해 소나무재의 역학적 특성 및 급속오븐 건조특성

황원중,권구중,박종수,김남훈 한국목재공학회 2003 목재공학 Vol.31 No.4

본 연구에서는 산불 피해 소나무재의 이용을 위한 기초자료를 얻고자 역학적 및 건조 특성을 조사하였다. 산불피해재는 종압축 특성, 전단강도, 충격휨흡수에너지 등에서 건전재와 거의 유사한 결과를 보여주었으며, 산불피해재 변재부의 휨특성은 건전재보다 양호하게 나타났다. 건전재와 산불피해재 변재부의 생재함수율은 산불피해재가 다소 낮았으나, 건조속도는 거의 차이가 없었다. 건조시 발생되는 초기할렬은 건전재가 산불피해재보다 발생율이 높았고, 내부할렬은 건전재와 산불피해재에서 발생되지 않았다. 따라서 산불에 의해 피해를 입은 목재의 대부분은 수피부를 제거하여 이용할 경우 건전재와 거의 동일한 용도로서 사용이 가능할 것으로 생각된다. The Mechanical and drying characteristics of Pinus densiflora wood, which was damaged by forest fire, and sound wood were examined. There were no significant differences in axial compressive properties, shearing strength and impact bending absorbed energy between damaged and sound woods. But the bending properties of damaged wood were slightly higher than those of sound wood. The green moisture content of sapwood in damaged wood was lower than that in sound wood, but oven-drying rate was similar in both woods. Number of initial check in damaged wood was smaller than that in sound wood, and inner check in damaged and sound woods was not observed. Consequently, it is considered that mostly damaged wood by forest fire can be used for wood material after removing the considered that mostly damaged wood by forest fire can be used for wood material after removing the bark.

장기적 트립토판 결여식이 생쥐의 유해감각예민도에 미치는 영향

서영대,박제민,김명정,전명호,양구범,장세헌,강철중,김정태,김용식 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.1

The depressive patients can be divided into two subgroups by presence and absence of pain symptoms. Those without pain symptoms have blunted pain sensitivity whereas those with pain have normal range of pain sensitivity, and are clinically characterized by anxiety and irritability. The aim of the study is to test if these clinical profiles of the depressives with pain symptoms are related with reduced level of brain serotonin(5-HT). Forty four mice were randomly divided into two groups : one group to be bred with tryptophan free diet and the other with normal control diet, each for 4 weeks. Before the beginning of the breeding period, measured were locomotor activity by open field test, anxiety by elevated plus maze and nociceptive sensitivity by tail flick test, before and after forced swimming(FS). During each FS, duration of immobilization was also measured. The sable sets of measurements were repeated at the end of the breeding period. The brain 5-HT and 5-hydroxyindoleacetic acid(5-HIAA) were measured by high performance liquid chromatography. The results were as follows 1.Four weeks of tryptophan free diet reduced significantly body weight, brain weight, and levels of 5-HT and 5-HIAA in the whole brain. 2.Tryptophan depletion did not influence basal nociceptive sensitivity as measured by tail flick latency before FS. The normal blunting of the pain sensitivity induced by forced swimming was preserved in the tryptophan depleted group. 3.Tryptophan depletion did not influence general locomotor activity in open field. 4.Tryptophan depletion increased significantly time spent on the open arms at the elevated plus maze test done before FS. This anxiolytic-like effect was reduced by FS. 5.Tryptophan depletion did not influence duration of immobilization during FS. From these results, it is suggested that the genesis of the depression with pain symptoms is not medicated by quantitative reduction of brain serotonin

Isolation and Characterization of Dextrans Produced by Leuconostoc sp. strain JYY4 from Fermented Kimchi

Gu, Ji-Joong,Ha, Yoo-Jin,Yoo, Sun-Kyun The Korean Society of Applied Science and Technolo 2015 한국응용과학기술학회지 Vol.32 No.4

Dextran is a generic term for a bacterial exopolysaccharide synthesized from sucrose and composed of chains of D-glucose units connected by ${\alpha}$-1,6-linkages by using dextransucrases. Dextran could be used as vicosifying, stabilizing, emulsifying, gelling, bulking, dietary fiber, prebiotics, and water holding agents. We isolated new strain capable of producing dextran from Korean traditional kimchi and identified as Leuconostoc sp. strain JYY4. Batch fermentation was conducted in bioreactor with a working volume of 3 L. The media was MMY and 15% (w/v) sucrose. Mineral medium consisted of $3.0g\;KH_2PO_4$, $0.01g\;FeSO_4$, $H_2O$, $0.01g\;MnSO_4$, $4H_2O$, $0.2g\;MgSO_4\;7H_2O$, 0.01 g NaCl, $0.05g\;CaCl_2$ per 1 liter deionized water. The pH of media was initially adjusted to 6.0. The inoculation rate was 1.0% (v/v) of the working volume. Temperature was maintained at $28^{\circ}C$. The agitation rate was 100 rpm. The production pattern of dextran was associated with the cell growth. After 24 hr dextran reached its highest concentration of 59.4 g/L. The sucrose was consumed completely after 40 hr. Growth reached stationery phase when sucrose became limiting, regardless of the presence of fructose or mannitol. When the specific growth rate was 0.54 hr-1, utilization averaged 5.8 g/L-hr. The yield and productivity of dextran were 80% and 2.0 g/L-hr, respectively. Dextrans produced by were separated to two different size by an alcohol fraction method. The size of high molecular weight dextran (45% alcohol, v/v), less soluble dextran, was between MW 500,000 and 2,000,000. Soluble dextran (55% alcohol, v/v) was between 70,000 and 150,000. The molecular weight average of total dextran (70% alcohol, v/v) was between 150,000 to 500,000. The enzymatic hydrolyzates of total dextran of ATCC 13146 showed branched dextrans by Penicillium dextranase contained of glucose, isomaltose, isomaltotriose, and isomaltooligosaccharides greater than DP4 (degree of polymerization) that had branch points. Compounds greater than DP4 were branched isomaltooligosaacharides. Hydrolysates by the Lipomyces dextranase produced the same composition of oligosaccharides as those by Penicillin dextranase.

Event-related Potential Patterns Reflect Reversed Hemispheric Activity during Visual Attention Processing in Children with Dyslexia: A Preliminary Study

Joong-Gu Kang,Seung-Hwan Lee,Eun-Jin Park,Hyun-Sung Leem 대한정신약물학회 2016 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.14 No.1

Objective: Individuals with dyslexia experience reading difficulties, whereas their other cognitive abilities seem normal. The pur-pose of this study was to investigate the event-related potential (ERP) patterns of children with dyslexia during a target-detection task. Methods: Seventeen children with dyslexia and 18 children without this disorder participated in this study. We evaluated their writing and reading ability, symptoms of attention-deficit/hyperactivity disorder, and intelligence quotient. ERPs were recorded while participants performed a target-detection task, and the peak amplitude and latency of P100 and P300 were analyzed. The lateral asymmetry index (LAI) was calculated for each ERP component. Results: The dyslexic group exhibited longer reaction times and larger P100 amplitudes than the non-dyslexic group in the right hemisphere. The P100 latency was also significantly delayed in the right hemisphere of those in the dyslexic group compared with those in the non-dyslexic group. The P300 amplitude was larger in the right hemisphere compared with left hemisphere in the dyslexic group, whereas no interhemispheric differences were observed with respect to the P300 latency. The LAI for P100 showed a significant right hemispheric dominance, whereas the LAI for P100 was significantly correlated with the accuracy of target detection in children with dyslexia. Conclusion: Our results suggest that right hemispheric dominance acts as an ancillary system that compensates for poor reading in children with dyslexia.

Characteristics of White Charcoal Produced from the Charcoal Kiln for Thermotherapy(온열욕 겸용 숯가마에서 생산된 백탄의 특성)

( Gu Joong Kwon ),( Ah Ran Kim ),( Hee Soo Lee ),( Seung Hwan Lee ),( Wahyu Hidayat ),( Fauzi Febrianto ),( Nam Hun Kim ) 한국목재공학회 2018 목재공학 Vol.46 No.5

본 연구에서는 온열욕 겸용을 위해 제작한 숯가마와 전통식 숯가마에서 제조한 백탄의 특성에 대해서 비교, 검토하였다. 온열욕 겸용 숯가마는 밀폐된 숯가마에서 발생하는 미세먼지 및 유해가스와 같은 환경문제를 최소화하고 편안함과 안전성을 고려하여 제작하였다. 온열욕 겸용 숯가마에서 제조한 백탄은 전통식 숯가마의 백탄보다 회분과 휘발분이 다소 높았고 고정탄소가 다소 낮았다. 온열욕 겸용 숯가마에서 생산된 백탄의 밀도는 기존의 전통식 숯가마 백탄보다 약간 높았지만, 평형함수율과 pH는 거의 차이가 없었다. 발열량, 정련도, 경도와 해부학적 구조는 숯가마에 따른 차이가 없었다. 결론적으로 온열욕 겸용을 위해 개량된 숯가마에서 제조한 백탄은 국립산림과학원의 품질인증기준을 충족하였고, 온열욕 겸용 숯가마는 목탄제조에도 적합한 것으로 판단되었다. In this study, the characteristics of the white charcoal from charcoal kilns made for both charcoal production and thermotherapy and from the traditional charcoal kiln were compared and examined. A charcoal kiln for thermotherapy as a secondary purpose was made to minimize environmental problems such as fine dust and harmful gas generated from sealed charcoal kiln in consideration of comfort and safety. White Charcoal produced from the charcoal kiln for both charcoal production and thermotherapy had higher ash and volatile matter and lower fixed carbon than that from the traditional charcoal kiln. The density of the white charcoal produced from the charcoal kiln for both charcoal production and thermotherapy was slightly higher than that of the traditional one, but the equilibrium moisture content and pH were not significantly different. The calorific value, refinement degree, hardness and anatomical structure were not different between the two. It was concluded that the white charcoal produced from the advanced charcoal kiln for thermotherapy as a secondary purpose meets the quality certification standards of Korea Forest Research Institute.

Antioxidant properties of Angelica dahurica extracts fermented by probiotics strains isolated from gimchi

Joong Gu Ji,Sun Kyun Yoo 한국유화학회 2018 한국응용과학기술학회지 Vol.35 No.4

Abstract 1. Introduction 2. Materials and Method 3. Result and Discussion 4. Conclusion References