시스틴 결석 : 증례 보고 A Case Report

이길용,노준,정충식 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

Cystine calculi is the consequence of cystinuria, an autosomal recessive defect of the transepithelial of cystine and dibasic acids in the kidney and intestine. The hardness and frequent reccurrence of cystine stones present a special challenge to the urologist. we report a case of 15-year-old man who had a cystine calculi, which was successfully treated with percutaneous lithotripsy (PCNL), extracorporeal shock wave lithotripsy (ESWL) &edical therapy include high fluid intake, alkalinization and chelating agent.

螢光像 測定法으로 分析한 HUMACTBP2 遺傳座位에 대한 韓國人의 遺傳的 多樣性과 法醫學的 有用性

황적준,남용석,최하주,이혜린,한길로 大韓法醫學會 1997 대한법의학회지 Vol.21 No.1

The HUMACTBP2 locus was investigated to collect population genetic data in the Korean population and to evaluate the applicability for the forensic field. An Automatic fluorescent-based sequencer (377 automatic DNA sequencer, ABI) was used to detect amplified fragments of the HUMACTBP2 locus electrophoresed on 4% denaturing polyacrylamide sequencing gels. ACTBP2 allelic ladder consisting of different sizes of 18 alleles was constructed and employed as an internal size standard in combination with a GS-350 size standard for precision of allele-band sizing. By utilizing different fluorescent dyes, both the allelic ladders and samples were able to be analyzed in the same lane by 99% precision of allele-band sizing. Among the Korean population (n=224), 26 alleles in the range of 239-313 bp are determined. Allele No. 6 is found 45 times (0.100) which is mostly frequent, and the rest of allele is distributed with their relative frequency of 0.112-0.100. The comparison between observed and expected numbers of homozygous and heterozygous individuals confirms that ACTBP2 locus is in the state of Hardy-Weinberg equilibrium among the Korean population. The heterozygosity is 0.9389±0.0034(93.89%), and the power of discrimination)PD) and power of exclusion(PEX) are calculated to be 0.991(99.1%) and 0.890(89.0%), respectively, showing the high informativeness for individual identification. Thus, these results mean that the HUMACTBP2 locus can effectively be used for the forensic application.

신경베체트병에 의한 신경인성방광 : 증례보고

이길용,임건한,소영석,노준,김철성,장대수 朝鮮大學校 附設 醫學硏究所 2002 The Medical Journal of Chosun University Vol.27 No.2

The co-existence of mouth and genital ulceration with iritis was first defined as a syndrome by Behcet. It is now known to be a chronic and relapsing systemic disease, which involves many other systems. Neurogenic bladder dysfunction due to Behcet's disease, however, is extremely rare, and only a limited number of cases have been reported in the international literature. Voiding disfunction in Behcet's disease can be due to neurological or direct bladder involvement and can be related to bladder and sphmctehc components in both phases of micturition. We report on a 35-year old patient with a neuropathic bladder secondary to Behcet's disease.

친모의 유전자형을 알 수 없을 때 친자확인 유전자 검사

황적준,이재원,한길로,이혜승 大韓法醫學會 1999 대한법의학회지 Vol.23 No.1

In parentage testing DNA profiles are used to link the alleged father with paternity by matching their patterns. The probative value of a match is often calculated by multiplying together the estimated frequencies with which each particular VNTR or STR pattern occurs in a reference population. When this calculating method applies to the motherless case of paternity disputes, a calculation must usually be based on types determined for the child and the alleged father. In such case, the first consideration is to exclude a man from paternity of a child when the man did not have the child's paternal allele at some loci, or if the paternal allele cannot be determined, when the man had neither of the child's alleles. The second is to evaluate the DNA evidence when a man is not excluded by the paternal allele. This work is to provide theories of paternity analysis with three approach methods for the motherless case, and to evaluate their efficiency compared to the trio case when the man tested is not excluded. Consequently, the motherless case offers lower probability exclusion and questionable cumulative paternity index than those of the trio case as being typed with 14 STR loci(CSF1PO, THO1, TPOX, vWA, nity index than those of the trio case as being typed with 14 STR loci(CSF1PO, THO1, TPOX, vWA, D5S818, D13S317, D7S820, D16S539, FGA, D21S11, FES/FPS, F13A1, D18S80, D17S5). Since the motherless case in paternity disputes is less efficient for paternity exclusion of the child, the use of genetic maker systems with the higher value of mean exclusion chance(MEC) and exact levels of the relative probability of paternity must be of importance considered in the analysis of such deficiency cases.

고등학교에서 혼성학급 체육 활성화를 위한 레크리에이션 댄스 교육활동 사례

윤길준 조선대학교 학생지도연구소 2004 生活指導硏究 Vol.23 No.1

인터넷 게임이 중·고등학생의 학습활동에 미치는 영향

윤길준 조선대학교 학생지도연구소 2003 生活指導硏究 Vol.22 No.1

This study investigated the effects of internet games on learning activities in middle and high school students. Findings will be helpful for learning activities and student guidance when students use internet and internet games in their school and home life. Findings for this study are as follows; First, the effects of internet games on learning activities are not seriously affected on students who are in any grade or any school boundary. Second, students in urban area schools are more accessible to the internet games than agricultural and fishing area schools. But, most of all students are exposed to the risk of internet game-holic gradually. Third, parents are not approval the internet games when their children are playing internet games. Forth, the problems of game-holic are not yet seriously level, but a few students are over tastes of playing internet games. Suggestions for the study are as follows. The effects of internet games to the students will be more influencable on students' learning activities and school life. Parents have to continuously observe their children's behavior in school and spare time regard to using internet, and also researchers have to study more actively regard to internet games.

콘크리트 구조물용 GFRP리바의 기계적 특성에 관한 연구

한길영,이동기,김성용,전상기,최종대,박준식 조선대학교 에너지.자원신기술연구소 2000 에너지·자원신기술연구소 논문지 Vol.22 No.2

In this paper was studied on the mechanical characteristics of Glass Fiber Reinforced Plastics(GFRP) of the steel bar it is to replace The advantage of FRP such as high strength low weight and chemical inertness or noncorrosiveness can be fully exploited. GFRP bar were successfully fabricated at 10mm nominal diameters and hollow types using a pultrusion method Tensile and bending specimens from this bar were tested and compared with behavior of GFRP rebar and steel bar.

퉁퉁마디로부터 염에 의하여 유도되는 Aldolase 유전자의 분리 및 발현분석

차준영,네티 엘마와티,김순길,이증주,임채오,정우식,이곤호,손대영 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Soil salinity is one of the most serious abiotic stresses limiting the productivity of agricultural crops. To cope with salt stress, plants respond with physiological, developmental and biochemical changes, including the synthesis of a number of proteins and the induction of gene expression. Salicornia herbacea is a halophytic plant that grows in salt marches and on muddy seashores. In order to understand the biochemical and molecular mechanisms of salt tolerance in S. herbacea, we isolated several genes that involved in the salt tolerance by mRNA differential display.Here we report the cloning of a cDNA encoding fructose-1, 6-bisphosphate aldolase, named ShADL, which is 1293 bp long and contains an open reading frame consisted of 359 amino acids with calculated molecular mass of 39 kDa. ShADL protein showed 86% identity with Arabidopsis and 78% with aldolase of common ice plant. Northern blot analysis revealed that the transcript of ShADL gene was increased dramatically depending on the NaCI concentrations.

中世美術作品 'Macabre'에 대한 法醫學的 考察

黃迪駿,韓吉路,文國眞 大韓法醫學會 1999 대한법의학회지 Vol.23 No.1

The word 'Macabre' was first used as an ordinart adjective by franch romantic writers in the 19th C. and was applied by them to anything both laugubrious and grotesque. It's original appliaction was the Dance Macabre and the was of macabre in slang to mean 'corpse' probably derived from 'dance macabre'. As a term in morden art criticism 'macabre' has lost its association with the dance of death and indicates, anything picture or sculpture related with putrefacted body. In the medieval day, according to conceptional change of death from the judgement to the transiency, the form of macabre also changed 'transi', 'priant' and 'vanitus' etc. The term of 'gisant' used on wards for a lying or recumbant effigy on a funerary monument the 'gisant' typically represented a person in death and the 'gisant' position was contrasted with the 'priasnt', which represented the person as it alive in a kneeling or praying position which expressed prayer of resurrection and the fomer was revealed transiency. Finally 'vanitus' produced a moment to make an autopsy to know the cause of death or to solve the legal problems. Authous foundout that the variation of form of 'macabre' was clossly linked with conceptional change of death and therefore, authors reviewed 'macabre' and discussed medicolegal significance of it.

119구급대를 통한 서울지역 외상환자 진료체계에 대한 통계분석

서길준,이승한,조익준,권운용,송형곤,이중의,윤여규 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Backgroud: Despite continous efforts to improve the prehospital trauma care system in Korea, the preventable death rate has been reported to be high. The purpose of this study was to evaluate the prehospital trauma care system in Seoul by analyzing 119 rescue databases. Methods: The 119 rescue data bases of 22,275 trauma patients, who were transported to the secondary and tertiary hospital in Seoul by Seoul 119 rescue services from January 1, 2000 to December 31, 2000, were analyzed. Results: The response time(mean 3.7 min.) showed no time, weekly, and regional variations. However, the transport time from field to hospital showed was high in the morning rush hour(7:00 to 10:00 am), and was gradually decreased and the lowest between 10:00 pm and 7:00 am. There was also a regional variation in the transport time, which was short in the central area and long in the peripheral area of Seoul. Prehospital cares were given to the 10,999 trauma patients(49.4%). Of the 464 unresponsive patients(2%), only 236 patients were identified in transported hospitals. The outcomes of these unresponsive patients were DOA(54%), survival(19%), death in ER(14%), transfer to other hospitals(8%), and death after admission(5%) in order. Conclusion: We suggest that this study may be helpful to the establishment and improvement of the prehospital trauma care system as well as the determination of the adequate numbers and locations of trauma center in Seoul.