Learning in Earliest Christian History: The Portrayal of Education within the Acts of the Apostles

Jonathon Lookadoo(Jonathon Lookadoo ) 장로회신학대학교 성서학연구원 2022 성서학 연구원 저널 Vol.113 No.1

Creation and Sovereignty: The Translation and Early Reception of John 1:3

Jonathon Lookadoo 한국신학정보연구원 2021 Canon&Culture Vol.15 No.2

본 논문은 요한복음의 서문, 즉, 요한복음 1장 3절이, (1) 주로 창조에서, (2) 좀 더 넓게는 하나님의 주권적 계획의 완성에서, 말씀이신 이의 매개적 행동을 가리키는지에 대한 해석에 있어 요한복음의 초기 수신자들 사이에서 발생한 어려움을 살펴본다. 해당 구절을 해석하는 것의 어려움은 요한복음을 라틴어와 시리아어로 번역한 고대 번역본들에서 자명하게 드러난다. 본고는 먼저 요한복음 1장 3절이 초기 번역본들에서 대안적으로 해석된 것이 분명함을 보인 후, 해당 구절이 2세기에 어떻게 수신되었는지에 대해 검토한다. 대부분의 2세기 독자들은 요한복음 1장 3절을, 창조에 있어 말씀이신 이의 행하심에 대한 관점으로 이해하였다. 그러나 몇몇 2세기 텍스트들은 요한복음 1장 3절을 하나님께서 역사 속에서 말씀이신 이를 통해 일하신 것을 묘사하기 위해 사용하였다. 본고는 이러한 관찰을 바탕으로 요한복음 1장 3절을 생산적인 모호성의 예로 읽는 것이 가장 적절함을 주장하고자 한다. 문장 속의 모호함은 독자들이 다양한 방식으로 읽는 것을 가능하게 하는데 이는 요한복음의 서문뿐만 아니라 네 번째 복음의 나머지 부분을 이해하는데도 도움이 되기 때문이다. 말씀이신 이는 하나님께서 모든 것을 지으신 매개자이신 동시에 하나님의 계획이 실행되는 통로이시다. This paper explores a difficulty that arose among early readers of the Johannine prologue, namely, whether John 1:3 refers to the Word’s mediatorial actions (1) primarily in creation or (2) more broadly in the outworking of God’s sovereign plan. The challenge of interpreting this verse is evident in the ancient translations of the Gospel of John into Latin and Syriac. After showing that alternative readings are evident in early translations, the article turns to the reception of John 1:3 in the second century. Most second-century readers elucidate John 1:3 with a view to the Word’s activity in creation, but some second-century texts utilize the verse to portray God’s work through the Word in history. Working from these observations, the paper argues that John 1:3 is best read as an example of productive ambiguity. In other words, the ambiguity in the sentence enables readers to produce multiple readings that are helpful in understanding both the Johannine prologue and the rest of the Fourth Gospel. The Word is both the mediator through whom God created all things and the one through whom God’s plans are made effective.

Topic Classification for Suicidology

Jonathon Read,Erik Velldal,Lilja Øvrelid 한국정보과학회 2012 Journal of Computing Science and Engineering Vol.6 No.2

Computational techniques for topic classification can support qualitative research by automatically applying labels in preparation for qualitative analyses. This paper presents an evaluation of supervised learning techniques applied to one such use case, namely, that of labeling emotions, instructions and information in suicide notes. We train a collection of one-versus-all binary support vector machine classifiers, using cost-sensitive learning to deal with class imbalance. The features investigated range from a simple bag-of-words and n-grams over stems, to information drawn from syntactic dependency analysis and WordNet synonym sets. The experimental results are complemented by an analysis of systematic errors in both the output of our system and the gold-standard annotations.

Computed tomography-guided 3D printed patient-specific regional anesthesia

Jonathon S. Jundt,Christopher C. Chow,Marcus Couey 대한치과마취과학회 2020 Journal of Dental Anesthesia and Pain Medicine Vol.20 No.5

Classic anesthetic techniques for the inferior alveolar nerve, lingual nerve, and long buccal nerve blockade are achieved by estimating the intended location for anesthetic deposition based on palpation, inspection, and subsequent correlation for oral anatomical structures. The present article utilizes computed tomography (CT) data to 3D print a guide for repeatable and accurate deposition of a local anesthetic at the ideal location. This technical report aims to anatomically define the ideal location for local anesthetic deposition. This process has the potential to reduce patient discomfort, risk of nerve damage, and failed mandibular anesthesia, as well as to reduce the total anesthetic dose. Lastly, as robotic-based interventions improve, this provides the initial framework for robot-guided regional anesthesia administration in the oral cavity.

Self-Limiting Electrodeposition of Hierarchical MnO₂ and M(OH)₂/MnO₂ Nanofibril/Nanowires: Mechanism and Supercapacitor Properties

Duay, Jonathon,Sherrill, Stefanie A.,Gui, Zhe,Gillette, Eleanor,Lee, Sang Bok American Chemical Society 2013 ACS NANO Vol.7 No.2

<P>Hierarchical nanostructures have generated great interest in the energy, materials, and chemical sciences due to the synergic properties of their composite architectures. Herein, a hierarchical MnO<SUB>2</SUB> nanofibril/nanowire array is successfully synthesized. The structure consists of a conformal layer of MnO<SUB>2</SUB> nanofibrils evenly distributed on the surface of the individual MnO<SUB>2</SUB> nanowires. The synthetic mechanism of this hierarchical structure is characterized by electrochemical measurements, Raman spectroscopy, EELS, and electron microscopy. This material was then investigated at slow scan rates for its charge storage mechanisms in different solvents. In aqueous electrolyte, the nanofibrils show a capacitance almost purely dedicated to double-layer and surface adsorption processes, while in an acetonitrile electrolyte, the nanofibrils’ capacitance comes mainly from a cation insertion process. This material was also tested at high scan rates in aqueous solution for its practical supercapacitor capabilities. The material shows a large capacitance of 298 F/g at 50 mV/s and 174 F/g at 250 mV/s. It also maintains 85.2% of its capacitance after 1000 cycles. The material also displays easily controllable parameters such as nanowire length, nanowire diameter, and amount of nanofibril material which is shown here to affect the capacitance dramatically.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2013/ancac3.2013.7.issue-2/nn3056077/production/images/medium/nn-2012-056077_0014.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn3056077'>ACS Electronic Supporting Info</A></P>

Topic Classification for Suicidology

Read, Jonathon,Velldal, Erik,Ovrelid, Lilja Korean Institute of Information Scientists and Eng 2012 Journal of Computing Science and Engineering Vol.6 No.2

Computational techniques for topic classification can support qualitative research by automatically applying labels in preparation for qualitative analyses. This paper presents an evaluation of supervised learning techniques applied to one such use case, namely, that of labeling emotions, instructions and information in suicide notes. We train a collection of one-versus-all binary support vector machine classifiers, using cost-sensitive learning to deal with class imbalance. The features investigated range from a simple bag-of-words and n-grams over stems, to information drawn from syntactic dependency analysis and WordNet synonym sets. The experimental results are complemented by an analysis of systematic errors in both the output of our system and the gold-standard annotations.

Colonic Inhibition of Phosphatase and Tensin Homolog Increases Colitogenic Bacteria, Causing Development of Colitis in Il10-/- Mice

Mitchell, Jonathon,Kim, Su Jin,Koukos, Georgios,Seelmann, Alexandra,Veit, Brendan,Shepard, Brooke,Blumer-Schuette, Sara,Winter, Harland S,Iliopoulos, Dimitrios,Pothoulakis, Charalabos,Im, Eunok,Rhee, Oxford University Press 2018 Inflammatory bowel diseases Vol.24 No.8

Src family kinase tyrosine phosphorylates Toll-like receptor 4 to dissociate MyD88 and Mal/Tirap, suppressing LPS-induced inflammatory responses

Mitchell, Jonathon,Kim, Su Jin,Seelmann, Alexandra,Veit, Brendan,Shepard, Brooke,Im, Eunok,Rhee, Sang Hoon Elsevier 2018 Biochemical pharmacology Vol.147 No.-

<P><B>Abstract</B></P> <P>Src family kinases (SFKs) are a family of protein tyrosine kinases containing nine members: Src, Lyn, Fgr, Hck, Lck, Fyn, Blk, Yes, and Ylk. Although SFK activation is a major immediate signaling event in LPS/Toll-like receptor 4 (TLR4) signaling, its precise role has remained elusive due to various contradictory results obtained from a certain SFK member-deficient mice or cells. The observed inconsistencies may be due to the compensation or redundancy by other SFKs upon a SFK deficiency. The chemical rescuing approach was suggested to induce temporal and precise SFK activation in living cells, thereby limiting the chance of cellular adaption to a SFK-deficient condition.</P> <P>Using the rescuing approach, we demonstrate that restoring SFK activity not only induces tyrosine phosphorylation of TLR4, but also inhibits LPS-induced NFκB and JNK1/2 activation and consequently suppresses LPS-induced cytokine production. TLR4 normally recruits TIR domain-containing adaptors in response to LPS, however, temporally restored SFK activation disrupts the LPS-induced association of MyD88 and Mal/Tirap with TLR4. Additionally, using kinase-dead SFK-Lyn (Y397/508F) and constitutively active SFK-Lyn (Y508F), we found that the kinase-dead SFK inhibits TLR4 tyrosine phosphorylation with reduced binding affinity to TLR4, while the kinase-active SFK strongly binds to TLR4 and promotes TLR4 tyrosine phosphorylation, suggesting that SFK kinase activity is required for TLR4 tyrosine phosphorylation and TLR4-SFK interaction.</P> <P>Together, our results demonstrate that SFK activation induces TLR4 tyrosine phosphorylation, consequently dissociating MyD88 and Mal/Tirap from TLR4 and inhibiting LPS-induced inflammatory responses, suggesting a negative feedback loop regulated by SFK-induced tyrosine phosphorylation in TLR4.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Highly flexible pseudocapacitor based on freestanding heterogeneous MnO₂/conductive polymer nanowire arrays

Duay, Jonathon,Gillette, Eleanor,Liu, Ran,Lee, Sang Bok The Royal Society of Chemistry 2012 Physical chemistry chemical physics Vol.14 No.10

<P>Flexible electronics such as wearable electronic clothing, paper-like electronic devices, and flexible biomedical diagnostic devices are expected to be commercialized in the near future. Flexible energy storage will be needed to power these devices. Supercapacitor devices based on freestanding nanowire arrays are promising high power sources for these flexible electronics. Electrodes for these supercapacitor devices consisting of heterogeneous coaxial nanowires of poly (3,4-ethylenedioxythiophene) (PEDOT)-shell and MnO<SUB>2</SUB>-core materials have been shown in a half cell system to have improved capacitance and rate capabilities when compared to their pure nanomaterials; however, their performance in a full cell system has not been fully investigated. Herein, these coaxial nanowires are tested in both a symmetric and an asymmetric (utilizing a PEDOT nanowire anode) full cell configuration in the aspect of charge storage, charge rate, and flexibility without using any carbon additives and polymer binders. It is found that the asymmetric cell outperforms the symmetric cell in terms of energy density, rate capability, and cycle ability. The asymmetric device's electrode materials display an energy density of 9.8 Wh/kg even at a high power density of 850 W kg<SUP>−1</SUP>. This device is highly flexible and shows fast charging and discharging while still maintaining 86% of its energy density even under a highly flexed state. The total device is shown to have a total capacitance of 0.26 F at a maximum voltage of 1.7 V, which is capable of providing enough energy to power small portable devices.</P> <P>Graphic Abstract</P><P>Highly flexible supercapacitor device using MnO<SUB>2</SUB>/conductive polymer coaxial nanowire arrays with a practical capacitance of 0.26 F at a voltage of 1.7 V. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cp00019a'> </P>

Structural Modeling of Cruise Destination Image, Travel Experience, and Behavioral Intention: A Case of Jeju Island

이상철,Jonathon Day 한국해양수산개발원 2016 해양정책연구 Vol.31 No.1

The present research investigated cruise travel perceptions of Asian cruise destinations using Jeju Island as an example. The study also examined the hypothetical relationships among key constructs such as destination image, onboard cruise experience, cruise experience at destination, overall satisfaction, and behavioral intention, using Structural Equation Modeling (SEM). According to the survey results, the destination image of Jeju Island consisted of five domains: ‘Safety and Cleanliness’, ‘Natural Environment and Weather’, ‘Culture and Heritage’, ‘Convenience’, and ‘Leisure Activities’. The cruise travel experience also consisted of two domains: onboard cruise experience and cruise experience at destination. SEM results showed that overall image of cruise destination affected cruise travelers’ perceptions concerning onboard cruise experience and cruise experience at destination. Travelers’ perceptions directly affected travelers’ overall satisfaction. It also affected travelers’ behavioral intention.