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      • KCI등재후보

        A STUDY ON INDUSTRIAL GAMMA RAY CT WITH ASINGLE SOURCE-DETECTOR PAIR

        JINSUP KIM,정성희,김종범 한국원자력학회 2006 Nuclear Engineering and Technology Vol.38 No.4

        Having its roots in medical applications, industrial gamma ray CT has opened up new roads for investigating and modelingindustrial processes. Using a line of research related to industrial gamma ray CT, the authors set up a system of single sourceand detector gamma transmission tomography for wood timber and a packed bed phantom. The hardware of the CT systemconsists of two servo motors, a data logger, a computer, a radiation source and a radiation detector. One motor simultaneouslymoves the source and the detector for a parallel beam scanning, whereas the other motor rotates the scan table at a presetprojection angle. The image is reconstructed from the measured projections by the filtered back projection method. The phantomwas designed to simulate a cross section of a packed bed with a void. The radiation source was 20mCi of Cs-137 and thedetector was a 1 inch 1 inch NaI (TI) scintillator shielded by a lead collimator. The experimental gamma ray CT imagehas sufficient resolution to reveal air holes and the density distribution inside the phantom. The system could possibly beapplied to a packed bed column or a pipe flow in a petrochemical plant.

      • KCI등재

        Fighting Corruption of Korea Customs Office

        Jinsup Kim(김진섭) 한국관세학회 2004 관세학회지 Vol.5 No.3

        Corruption thrives when public accountability is weak, where governments or political parties are inclined to pursue their own private agendas often disguising the true cost to their country, where there are big differences between public and private sector pay, and when there is impunity for the corrupt. The issue of fighting corruption should be addressed not by stop-gap measures and temporary remedies, but by systematic and comprehensive integrity enhancement measures. The Korea Customs Service(KCS) has diminished the opportunity of corruption through minimization of direct person-to-person contact between Customs officers and their clients by establishment of automated paperless Customs procedures.

      • A Subsystem based Real-time Vehicle Dynamics Model for ECU-in-the loop Simulations

        Jinsup Yun,Sung-Soo Kim,Wanhee Jeong 한국자동차공학회 2007 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

        To develop control subsystems for the intelligent vehicles, extensive vehicle tests are necessary to verify such control subsystems. However, actual vehicle tests are costly, time consuming, and sometimes dangerous. To save time and cost and to avoid dangerous situations for developing such systems, HILS (Hardware-In-the-Loop Simulation) vehicle simulator is one of the effective tools. In the HILS simulator, the software vehicle dynamics model must be solved in real¬time, and it must also reproduce real vehicle motions. The real-time multi body vehicle model based on the subsystem synthesis method has been developed. How-ever, it has not been applied to actual HILS system. In this paper, the real-time multibody vehicle dynamics model using subsystem synthesis method is applied to an ECU-in-the loop simulation system for semi-active suspension control simulations. RT-LAB real-time solution and Compact-RIO general purpose ECU(Electric Control Unit) are utilized to construct an ECU-in-the loop simulation system. Bump run simulations are carried out to verify HILS applicability of this model.

      • Introduction to the New Version of PWS Application and It's Use in Medical Practice

        Kim, Jinsup,Yang, Aram,Cho, Sung Yoon,Jin, Dong-Kyu Association for Research of MPS and Rare Diseases 2016 Journal of mucopolysaccharidosis and rare disease Vol.2 No.2

        Today's mobile phones and tablet PCs offer a considerably wider range of functionalities than before. Mobile applications (apps) are increasingly used for managing various daily health tasks. Currently, more than 165,000 health-related apps are offered on all the stores of different platforms. Pf Jin and the Association for Research on MPS and Rare Diseases (AMARD) have helped Prader-Willi syndrome (PWS) families through medical information and family support since 2015. AMARD developed the first mobile application for Korean patients with PWS, which was released to a limited number of patients under the age of 3 and only provided to Android users. The first version of the PWS application focused on growth hormone therapy and the assessment of growth and development by parents in infant and early-childhood PWS patients. The 2016 version of the PWS application has been improved in many different ways. We have expanded the subjects of the application to late childhood and adolescent groups, changed the user interface accordingly, and made the application available for iOS users. We will show the specialized growth curves of older children with PWS. Therefore, patients with PWS over the age of 3 and their parents can assess the patients' growth. Additionally, we have upgraded the growth hormone therapy menu by improving the input system for the growth hormone therapy injection schedule and the daily growth profile (height and weight). We expect that the new version of the PWS application will help many PWS families cope with growth hormone therapy and evaluate the effects of growth hormones in better ways. Additionally, we are making a constant effort to provide more useful information about patients with PWS in many aspects.

      • Beneficial Effects of Growth Hormone Treatment in Prader-Willi Syndrome

        Kim, Jinsup,Yang, Aram,Cho, Sung Yoon,Jin, Dong-Kyu Association for Research of MPS and Rare Diseases 2017 Journal of mucopolysaccharidosis and rare disease Vol.3 No.2

        Prader-Willi syndrome (PWS) is a genetic disorder that is considered, especially on child, to cause poor feeding, hypotonia, failure to thrive, developmental delay and hypogonadism which is known to affect between 1 in 10,000 and 30,000 people. The children with PWS are viewed as affected by growth hormone (GH) insufficiency, although the exact mechanisms of GH deficiency are not fully understood. However, the benefits of GH treatment in children with PWS are well established. Myers, et al. (2006), Grugni, et al. (2016) indicated its positive effects on linear growth, body composition, motor function, respiratory function and psychomotor development. Despite of its effectiveness and advantages had been well known and proven in many other studies, there is only one recombinant GH product that is approved for PWS in Korea, $Genotropin^{(R)}$, till now. A phase III clinical study of GH treatment with $Eutropin^{TM}$, in 34 Korean PWS children is in progress, which is expected to have comparable effects and safety profile with the active control by assessing auxological changes such as height standard deviation score, body composition changes such as lean body mass and percent body fat, motor and cognitive development using Bayley scale, and safety profiles.

      • SCISCIESCOPUS

        Uniform Graphene Quantum Dots Patterned from Self-Assembled Silica Nanodots

        Lee, Jinsup,Kim, Kyungho,Park, Woon Ik,Kim, Bo-Hyun,Park, Jong Hyun,Kim, Tae-Heon,Bong, Sungyool,Kim, Chul-Hong,Chae, GeeSung,Jun, Myungchul,Hwang, Yongkee,Jung, Yeon Sik,Jeon, Seokwoo American Chemical Society 2012 NANO LETTERS Vol.12 No.12

        <P>Graphene dots precisely controlled in size are interesting in nanoelectronics due to their quantum optical and electrical properties. However, most graphene quantum dot (GQD) research so far has been performed based on flake-type graphene reduced from graphene oxides. Consequently, it is extremely difficult to isolate the size effect of GQDs from the measured optical properties. Here, we report the size-controlled fabrication of uniform GQDs using self-assembled block copolymer (BCP) as an etch mask on graphene films grown by chemical vapor deposition (CVD). Electron microscope images show that as-prepared GQDs are composed of mono- or bilayer graphene with diameters of 10 and 20 nm, corresponding to the size of BCP nanospheres. In the measured photoluminescence (PL) spectra, the emission peak of the GQDs on the SiO<SUB>2</SUB> substrate is shown to be at ∼395 nm. The fabrication of GQDs was supported by the analysis of the Raman spectra and the observation of PL spectra after each fabrication step. Additionally, oxygen content in the GQDs is rationally controlled by additional air plasma treatment, which reveals the effect of oxygen content to the PL property.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2012/nalefd.2012.12.issue-12/nl302520m/production/images/medium/nl-2012-02520m_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl302520m'>ACS Electronic Supporting Info</A></P>

      • Lipoid Congenital Adrenal Hyperplasia Diagnosed in an Infant with Hyperpigmentation Only by Targeted Exome Sequencing

        Kim, Jinsup,Yang, Aram,Jang, Ja-Hyun,Cho, Sung Yoon,Jin, Dong-Kyu Association for Research of MPS and Rare Diseases 2017 Journal of mucopolysaccharidosis and rare disease Vol.3 No.1

        Lipoid congenital adrenal hyperplasia (LCAH) is the severe form of congenital adrenal hyperplasia and is characterized by adrenal insufficiency with hyperpigmentation and female external genitalia irrespective of genetic sex. The steroidogenic acute regulatory protein (StAR) is required for the transport of cholesterol into the mitochondria for steroidogenesis, and defects in the StAR gene account for the majority of LCAH cases. In this report, we present a two-day-old hyperpigmented infant with phenotypical female genitalia. With consideration of the clinical and laboratory findings, the infant was suspected of having adrenal insufficiency due to LCAH and treated with glucocorticoid, mineralocorticoid, and sodium chloride. Karyotyping revealed 46, XY. Upon pelvis ultrasonography, adrenal hyperplasia with abdominal masses (thought to be the testicles) was reported. Molecular analysis with targeted exome sequencing revealed the homozygote mutation of c.772C>T ($p.Q258^*$) in exon 7 of the StAR gene. The early detection and treatment of adrenal insufficiency in infants with hyperpigmentation can prevent clinically apparent adrenal crises. During follow-up, the patient had a good clinical condition and maintained normal electrolyte and adrenocorticotropic hormone levels with medication.

      • SCISCIESCOPUS

        High-Angle Tilt Boundary Graphene Domain Recrystallized from Mobile Hot-Wire-Assisted Chemical Vapor Deposition System

        Lee, Jinsup,Baek, Jinwook,Ryu, Gyeong Hee,Lee, Mi Jin,Oh, Seran,Hong, Seul Ki,Kim, Bo-Hyun,Lee, Seok-Hee,Cho, Byung Jin,Lee, Zonghoon,Jeon, Seokwoo American Chemical Society 2014 NANO LETTERS Vol.14 No.8

        <P>Crystallization of materials has attracted research interest for a long time, and its mechanisms in three-dimensional materials have been well studied. However, crystallization of two-dimensional (2D) materials is yet to be challenged. Clarifying the dynamics underlying growth of 2D materials will provide the insight for the potential route to synthesize large and highly crystallized 2D domains with low defects. Here, we present the growth dynamics and recrystallization of 2D material graphene under a mobile hot-wire assisted chemical vapor deposition (MHW-CVD) system. Under local but sequential heating by MHW-CVD system, the initial nucleation of nanocrystalline graphenes, which was not extended into the growth stage due to the insufficient thermal energy, took a recrystallization and converted into a grand single crystal domain. During this process, the stitching-like healing of graphene was also observed. The local but sequential endowing thermal energy to nanocrystalline graphenes enabled us to simultaneously reveal the recrystallization and healing dynamics in graphene growth, which suggests an alternative route to synthesize a highly crystalline and large domain size graphene. Also, this recrystallization and healing of 2D nanocrystalline graphenes offers an interesting insight on the growth mechanism of 2D materials.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2014/nalefd.2014.14.issue-8/nl5012323/production/images/medium/nl-2014-012323_0007.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl5012323'>ACS Electronic Supporting Info</A></P>

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