Development of red blood cell abnormality detection algorithm using YOLOv5

Jingu Kim,Jihun Kang,Kyoungcheol Choi,WoongKi Jang,Soonhwan Kwon,hojin Ha,Kwangsuk Lim,Byeong Hee Kim,Yongjai Park 한국생산제조학회 2022 한국생산제조시스템학회 학술발표대회 논문집 Vol.2022 No.5

Lycopene의 새로운 혈관내피세포 생리활성

Jingu Cho(조진구),Sunghyen Kim(김성현),Jeonghwa Seo(서정화),Sunyoung Ahn(안선영),Eunsil Jeong(정은실),Heonyong Park(박헌용) 한국생명과학회 2010 생명과학회지 Vol.20 No.7

항암 효과와 항산화 기능을 가지는 것으로 알려진 lycopene은 심혈관에서의 기능이 현재까지 잘 알려져 있지 않다. 본 연구에서는 lycopene의 심혈관 기능을 알기 위해 혈관내피세포를 이용해 다양한 세포실험을 수행하였다. 그 결과, lycopene은 내피세포의 성장 및 이동을 촉진하였으나 세포사멸에는 영향이 없었다. 또한, 백혈구의 혈관내피세포 부착을 억제하였고 내피세포 내 신호전달물질인 MAPK들의 활성을 촉발하였다. MAPK의 활성 억제제를 이용한 신호전달기전 연구실험 결과, ERK와 p38 MAPK의 활성은 세포성장에 관여하고, JNK의 활성은 세포이동에 관여함을 확인하였다. 종합하면, lycopene은 혈관내피세포의 신호전달 물질인 MAPK들를 통해 세포 성장 및 이동을 촉진시키며, LPS에 의한 THP-1의 내피세포 부착을 억제 하는 등 혈관내피세포의 다양한 생리활성을 조절한다. Lycopene의 이러한 혈관내피세포 기능들은 lycopene이 혈관질환 치료제로 응용될 가능성이 있음을 의미한다. Little is known about the cardiovascular effects of Lycopene, an anti-cancer and anti-oxidative agent. In this study, we executed a series of experiments with vascular endothelial cells to disclose the cardiovascular functions of lycopene. From our in vitro experiments, lycopene was determined to act as a stimulant to induce endothelial cell proliferation and migration. In addition, lycopene was shown to inhibit lipopolysaccharide (LPS)-induced adhesion of THP-1 leukocytes to endothelial cells, as well as activating mitogen activated protein kinase (MAPK) family members, ERK, JNK and p38 MAPK. Both ERK and p38 MAPK were involved in lycopene-induced cell proliferation, while JNK was involved in lycopene-dependent cell migration. Taken together, lycopene activates MAPK family members which regulate cell proliferation and migration. Lycopene differentially blocks LPS-dependent adhesion for THP-1 to endothelial cells, indicating that lycopene is likely to regulate a variety of vascular functions.

Control effects of natural enemy on the mites occurring in sawdust for rearing Protaetia brevitarsis (Coleoptera: Cetoniidae)

Jingu Lee,Seung-Hwan Yun,Jae Eun Jang,Jeong A Han,Sang-Woo Kim,Young Soon Lee 한국응용곤충학회 2020 한국응용곤충학회 학술대회논문집 Vol.2020 No.10

Introduction of two new natural enemies to control horticultural crop pest

Jingu Lee,Seung-Hwan Yun,Jae Eun Jang,Jeong A Han,Sangwoo Kim,Eun Hye Ham,Un Taek Lim 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.10

Health-enhancing Effects of feed supplemented with mealworm(Tenebrio molitor) on dog

Jingu Lee,Seung-Hwan Yun,Gab June Lim,Jae Eun Jang,Jieun Hwang,Seungju Lee,Sung Mo Yoon 한국응용곤충학회 2019 한국응용곤충학회 학술대회논문집 Vol.2019 No.04

Mealworm(Tenebrio molitor) was added to the feed to improve the health of dogs. As the amount of mealworm powder added to dog feed increased from 2.5 to 7.5%, the contents of crude protein, crude fat, crude fiber and crude ash increased. In the old dogs, creatinine and BUN related to nephropathy, triglyceride related to hypertension, calcium related to osteoporosis, globulin related to immunity, and ALT related to hepatic function were in the normal range. Particularly, ALT showed a tendency to increase overall, but the numerical increase tended to decrease as the amount of mealworm powder added. In the young dogs, all investigative items such as BUN and creatine were in the normal range and ALT tended to decrease at 2.5~5.0% treatment of mealworm. As a result, it was shown that adding 2.5~5.0% of mealworm powder to feed effectively improved the hepatic function of old and young dogs.

Biological Characteristics of Stick Insect, Baculum elongatum (Phasmida : Phasmatidae) to Develop for the Industrial Insect

JinGu Lee,AeGyeong Seo,HeeDong Kim,YoungBo Lee2,SangHyun Lee,YoungKyu Park,HaeGil Lee,ChangSung Kang 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.05

Stick insect has several peculiarities like parthenogenesis, unique external features and dropping oviposition, so it is very hopeful to use for industrial insect. The oviposition was established by only female without fertilization with sperm of male which was not discovered during this study. The oviposition period was 37.3±14.9 days and the number of eggs per female was 41.5±16.5 eggs. The hatchability was 73.3% at 25℃and 66.7% after low temperature treatment(8℃, 60 days). The developmental periods and the length of egg were 100.9±4.2 days and 0.33±0.0cm, respectively, and the adult's life span was 49.7±16.0days. Differently other research which reported five nymph stage, the developmental stages of nymph showed five(62.9%) or six(37.1%) stages. The duration and the length of nymph increased according to the increase of nymph stage. Stick insect preferred the leaf of American locust, White oak, Chestnut, Bush clover in order but could be reared with food of the leaf of all these trees. Stick insects are herbivorus but made an attack each other when encountered in the small space. For sustaining mass rearing of stick insect, it is needed that the development of artificial diet and high density rearing method.

Biological characteristics of Childrena zenobia (Lepidoptera : Nymphalidae) promising as an industrial insect

JinGu Lee,AeGyeong Seo,JingYoung Kim,JeongA Han,ChangSung Kang,YoungSu Lee,SangHyun Lee 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.04

Childrena zenobia is very hopeful as an industrial insect for its beautiful color and long life span. This study was conducted to establish the mass rearing methods of C. zenobia to develop it as an industrial insect. C. zenobia appeared in the high mountains of about 1,000m above sea level at Pocheon and Gapyoung during high temperature season from July to August, and in the low mountains of about 400m above sea level at Yeoncheon on September. The first oviposition time after mating took 27.8±9.0 days and the number of eggs per female was 180. The life span of adult was 39.3±20.2 days in male and 59.0±18.7 days in female. The hatchability of F1 generation showed high rate over 80% at 20∼30℃, while the rate of F5 generation was very low under 5%. The proper food for rearing the larva was Viola papilionacea. The developmental period from 1st larva to adult was 63.6±5.1 days and the hatching time was 8.7±0.9 days at 20℃ and 48.0±3.3 days and the hatching time was 8.1±1.2 days at 25℃. These results seemed to be very suggestive that C. zenobia could be massively reared in the condition of indoor rearing room resulting in the utilization of it as an industrial insect for various regional festivals.

A Study of Korean-Chinese Ethnic Cluster and Living Space Expansion

Jingu Kang,Yong-jun Park 중앙대학교 문화콘텐츠기술연구원 2015 다문화콘텐츠연구 Vol.0 No.20

This article aimed at understanding the reason, the characteristics, and the problems caused by the ethnic cluster residence of the Korean-Chinese (Chaoxianzu), focused on the example of Daelim‐dong, Yeongdeungpo-gu, which was the representative area of the Korean-Chinese. For the purpose of the study, a field survey and in-depth interviews were combined. Whereas the spatial characters of Daelim-dong were found in an on-the-spot survey, the understanding of various social relations of the Korean-Chinese was shown primarily by the in-depth interviews of those living in Daelim-dong. The results are as follows: First, the biggest reason of their clustering in Daelim-dong is comfortable living conditions, including convenient traffic facilities. They live in this area due to its perception as a place of convenient traffic, relatively cheaper prices, familiar food markets, and as a meeting place of familiar relatives and friends. The second reason is its strong migration network among the ethnic grouop, which allows them to buy their houses, and improve the condition of job employment and inappropriate discrimination by Koreans. Next, Daelim-dong changes physically into a space of cultural hybridity as Daelim-dong Chinatown, where Korean-Chinese migrators and Korean residents influence one another. Finally, with its concentrated population of Korean-Chinese, Daelim-dong is placed at a crossroad between degrading into an urban underclass residential place or emerging as a new center of culture and economic activities.

Study on the Hatching Characteristics and Diet of Stick Insect, Baculum elongatum (Phasmida : Phasmatidae) for Artificial Mass Rearing

JinGu Lee,HeeDong Kim,ChangSung Kang,AeGyeong Seo,SangHyun Lee,YoungKyu Park,YoungBo Lee 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.04

Baculum elongatum has a long, thin shape that resembles a twig, propagates by parthenogenesis, changes body color, and drops eggs, all of which suggests its potential in the commercial market, especially as an educational pet insect. This study was carried out to determine the best hatching environment and an alternative or artificial diet for rearing B. elongatum to be developed as a commercial and educational pet insect. Oviposition was performed by females without fertilization by the sperm of males. The oviposition period was 42.2 ± 22.7 days and the number of eggs per female was 109.5 ± 70.5 eggs. The hatch rate was 73.3% at 25°C and 66.7% after low temperature treatment (8°C for 60 days). In nature, B. elongatum overwinters as an egg, but it can be assumed from the results that cold temperatures were not required for hatching. The hatch rate was 98.2% in the treatment using floral foam, fermented sawdust, and leaves. Clover(Trifolium repens) was an excellent diet as it was similar to the host plant and could be used as an alternative diet. The rate of reaching adulthood for the insects was 66.7% on an artificial diet containing 25% acacia leaves. For sustainable mass rearing of nymphs or adults of B. elongatum, a natural diet could be used such as acacia (Robinia pseudoacacia), white oak (Quercus aliena), chestnut (Castanea crenata var. dulcis), and bush clover (Lespedeza bicolor), or an alternative diet such as clover or artificial diet. To rear nymphs and adults of B. elongatum, natural diet such as acacia, white oak, chestnut, or bush clover leaves, or an alternative diet such as clover or an artificial diet can be used.

연구관리전문기관 연구관리 담당자의 역량모델 연구

이진구(Jingu Lee),이용진(YongJin Lee),정일찬(Il Chan Jung),김지영(Jiyoung Kim) 중앙대학교 한국인적자원개발전략연구소 2017 역량개발학습연구 Vol.12 No.3

본 연구의 주요 목적은 연구관리전문기관에서 연구관리를 담당하는 인력에 대한 역량모델을 개발하는 것이다. 이를 위해 본 연구에서는 전문가 패널 접근법을 바탕으로 FGI와 델파이 기법을 활용하였다. 구체적으로는 1단계 직무역량 풀(pool) 구성, 2단계 역량모델 개발을 위한 FGI, 3단계 역량모델 개발을 위한 델파이 조사, 4단계 역량모델 및 역량 프로파일 작성, 5단계 우선개발 필요 역량 도출의 총 5단계로 연구를 실시하였다. 연구결과, 연구관리전문기관 연구관리 담당자의 직무는 기획, 평가관리, 성과확산의 3개로 도출되었고, 역량은 기획 직무에서는 정보수집 및 분석, 정책방향 수립, 과제기획력의 세 개의 역량이, 평가관리 직무에서는 규정 및 업무지식 활용, 프로젝 트(과제) 관리의 두 개의 역량이, 성과확산 직무에서는 성과관리 역량이 도출되었다. 직무수행에 필요한 지식·기술·태도는 기획 직무에서 지식 9개, 기술 8개, 태도 6개가 도출되었고, 평가관리 직무에서 지식 21개, 기술 12개, 태도 11개가 도출되었으며, 성과확산 직무에서 지식 5개, 기술 5개, 태도 4개가 도출되었다. 전문가 FGI 및 델파이 분석을 통하여 도출된 역량 중 우선개발 필요역량에 대한 우선순위 분석을 실시한 결과 1순위는 정보수집 및 분석, 2순위는 프로젝트(과제)관리와 정책방향 수립, 3순위는 과제기획력과 규정 및 업무지식 활용으로 나타났다. 이러한 연구결과를 바탕으로 연구관리 담당자의 역량과 체계적인 육성에 대한 시사점을 제시하였다. The main purpose of this research is to develop competency modeling involved with R&D management personnel. This study conducts a developing job competency pool, FGI, Delphi analysis, competency profile development, and prioritizing competency development based on expert panel approach. In the result, R&D management personnel tasks included (1) planning (2) assessment management and (3) result promotion. For the planning part, the competency of R&D management personnel involves the collection and analysis of information, deciding policy direction, and creating assignments, while assessment management competency involves using regulation, task knowledge, and managing projects. Result promotion involves outcome management. Collecting information, managing projects, deciding policy direction, planning assignments, and using regulation and task knowledge has been stated in order of priority. The results from this study can be used as a reference for R&D management personnel competency model and systematic training.