Numerical simulations and surrogate-based optimization of cavitation performance for an aviation fuel pump

Xing’an Zhao,Biao Huang,Tairan Chen,Guoyu Wang,Deming Gao,Jing Zhao 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.2

We used computational modeling to investigate the cavitation performance of an aviation fuel pump, and optimize structural parameters using the surrogate-based method. In the numerical simulation, a rotation-curvature correction was adapted to the k-ε turbulence model, and a four-component surrogate fuel was selected to reproduce the physical properties of the China RP-3 kerosene. Then the performance of the aviation fuel pump was predicted. In the optimization, based on the series of the numerical results, Surrogate-based analysis and optimization (SBAO) was used to optimize the structural parameters of the fuel pump (the variation of the outlet blade angle for the inducer △β b1 and the variation of the inlet blade angle for the impeller △β b2 ). The results show that the prediction of cavitation performance agrees well with the experimental data. The results show that cavitation areas are mainly distributed in the inlet of the inducer. The volume of cavities grows with the decreasing NPSHa. The head of the fuel pump has a sudden head-drop when NPSHa ≤ 5.64 m. Furthermore, the surrogate-based approach is available in structural optimization of the fuel pump. The cavitation performance of the optimized pump improved about 22 % with a little drop of head coefficient when △β b1 = 4.33° and △β b2 = 3.24°. The numerical approach employed in this paper can accurately predict the cavitating flow of the high rotating speed fuel pump and the surrogate-based method is available in the structural optimization for a better cavitation performance.

Efficacy of Prophylactic Entecavir for Hepatitis B Virus-Related Hepatocellular Carcinoma Receiving Transcatheter Arterial Chemoembolization

Li, Xing,Zhong, Xiang,Chen, Zhan-Hong,Wang, Tian-Tian,Ma, Xiao-Kun,Xing, Yan-Fang,Wu, Dong-Hao,Dong, Min,Chen, Jie,Ruan, Dan-Yun,Lin, Ze-Xiao,Wen, Jing-Yun,Wei, Li,Wu, Xiang-Yuan,Lin, Qu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.18

Background and Aims: Hepatitis B virus (HBV) reactivation was reported to be induced by transcatheter arterial chemoembolization (TACE) in HBV-related hepatocellular carcinonma (HCC) patients with a high incidence. The effective strategy to reduce hepatitis flares due to HBV reactivation in this specific group of patients was limited to lamivudine. This retrospective study was aimed to investigate the efficacy of prophylactic entecavir in HCC patients receiving TACE. Methods: A consecutive series of 191 HBV-related HCC patients receiving TACE were analyzed including 44 patients received prophylactic entecavir. Virologic events, defined as an increase in serum HBV DNA level to more than 1 log10 copies/ml higher than nadir the level, and hepatitis flares due to HBV reactivation were the main endpoints. Results: Patients with or without prophylactic were similar in host factors and the majorities of characteristics regarding to tumor factors, HBV status, liver function and LMR. Notably, cycles of TACE were parallel between the groups. Ten (22.7%) patients receiving prophylactic entecavir reached virologic response. The patients receiving prophylactic entecavir presented significantly reduced virologic events (6.8% vs 54.4%, p=0.000) and hepatitis flares due to HBV reactivation (0.0% vs 11.6%, p=0.039) compared with patients without prophylaxis. Kaplan-Meier analysis illustrated that the patients in the entecavir group presented significantly improved virologic events free survival (p=0.000) and hepatitis flare free survival (p=0.017). Female and Eastern Cooperative Oncology Group (ECOG) performance status 2 was the only significant predictors for virological events in patients without prophylactic antiviral. Rescue antiviral therapy did not reduce the incidence of hepatitis flares due to HBV reactivation. Conclusion: Prophylactic entecavir presented promising efficacy in HBV-related cancer patients receiving TACE. Lower performance status and female gender might be the predictors for HBV reactivation in these patients.

Biota Great Migrations and the Climate Changes since the Late Pleistocene(100,000 years B.P.) in the Eastern China

Lin, Jing-Xing 선문대학교 통일사상연구원 2000 통일사상 연구논총 Vol.7 No.-

The study area includes liaoning, Hebei, Shandong, Jiangsu, Zhejiang, Fujian, Taiwan, Guangdong, Guangxi, Hainan Province, Beijing, Tianjin, Shanghai City, the Bohai Sea, the Yellow Sea, the East China Sea, and the South China Sea. The total area covers approximately 6.25 million square kilometers (2.56 million square kilometers in the land, 3.6 million square kilometers in the sea) This area supports about 430 million people, and include three climate zones; the temperate zone, the subtropical zone, and the tropical zone. The study areas are classified as two regions: (1) The great plain region, including the Yangtze River Delta Plain, the North China Plain, the Liao River Delta Plain, North Jiangsu Plain, and North Zhejiang Plain. (2) The bedrock coastal plain region, including: the North China coastal plain (the Liaodong Peninsula coastal plain, the Jidong coastal plain, the Shandong Peninsula coastal plain);and the Southeast China coastal plain (the south Zhejiang, Fujian, Leizhou Peninsula and the Hainan Island coastal plain).

Staged Improvement in Awareness of Disease for Elderly Cancer Patients in Southern China

Li, Xing,Dong, Min,Wen, Jing-Yun,Wei, Li,Ma, Xiao-Kun,Xing, Yan-Fang,Deng, Yun,Chen, Zhan-Hong,Chen, Jie,Ruan, Dan-Yun,Lin, Ze-Xiao,Wang, Tian-Tian,Wu, Dong-Hao,Liu, Xu,Hu, Hai-Tao,Lin, Jia-Yu,Li, Zhu Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

Background: In mainland China, awareness of disease of elderly cancer patients largely relies on the patients' families. We developed a staged procedure to improve their awareness of disease. Materials and Methods: Participants were 224 elderly cancer patients from 9 leading hospitals across Southern China. A questionnaire was given to the oncologists in charge of each patient to evaluate the interaction between family and patients, patient awareness of their disease and participation in medical decision-making. After first cycles of treatment, increased information of disease was given to patients with cooperation of the family. Then patient awareness of their disease and participation in medical decision-making was documented. Results: Among the 224 cancer elderly patients, 26 (11.6%) made decisions by themselves and 125 (55.8%) delegated their rights of decision-making to their family. Subordinate family members tended to play a passive role in decision-making significantly. Patients participating more in medical decision-making tended to know more about their disease. However, in contrast to the awareness of disease, patient awareness of violation of medical recommendations was reversely associated with their participation in medical decision-making. Improvement in awareness of diagnosis, stages and prognosis was achieved in about 20% elderly cancer patients. About 5% participated more actively in medical decision-making. Conclusions: Chinese elderly cancer patient awareness of disease and participation in medical decision-making is limited and relies on their family status. The staged procedure we developed to improve patient awareness of disease proved effective.

The Visible Human Projects in Korea and China with improved images and diverse applications.

Dai, Jing-Xing,Chung, Min Suk,Qu, Rong-Mei,Yuan, Lin,Liu, Shu-Wei,Shin, Dong Sun Springer International 2012 Surgical and radiologic anatomy Vol.34 No.6

<P>The Visible Human Projects, which were launched in the United States, have also been developed in Korea and China during the past decade. This article includes the new trials to promote a variety of their applications.</P>

Modeling Age-specific Cancer Incidences Using Logistic Growth Equations: Implications for Data Collection

Shen, Xing-Rong,Feng, Rui,Chai, Jing,Cheng, Jing,Wang, De-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Large scale secular registry or surveillance systems have been accumulating vast data that allow mathematical modeling of cancer incidence and mortality rates. Most contemporary models in this regard use time series and APC (age-period-cohort) methods and focus primarily on predicting or analyzing cancer epidemiology with little attention being paid to implications for designing cancer registry, surveillance or evaluation initiatives. This research models age-specific cancer incidence rates using logistic growth equations and explores their performance under different scenarios of data completeness in the hope of deriving clues for reshaping relevant data collection. The study used China Cancer Registry Report 2012 as the data source. It employed 3-parameter logistic growth equations and modeled the age-specific incidence rates of all and the top 10 cancers presented in the registry report. The study performed 3 types of modeling, namely full age-span by fitting, multiple 5-year-segment fitting and single-segment fitting. Measurement of model performance adopted adjusted goodness of fit that combines sum of squred residuals and relative errors. Both model simulation and performance evalation utilized self-developed algorithms programed using C# languade and MS Visual Studio 2008. For models built upon full age-span data, predicted age-specific cancer incidence rates fitted very well with observed values for most (except cervical and breast) cancers with estimated goodness of fit (Rs) being over 0.96. When a given cancer is concerned, the R valuae of the logistic growth model derived using observed data from urban residents was greater than or at least equal to that of the same model built on data from rural people. For models based on multiple-5-year-segment data, the Rs remained fairly high (over 0.89) until 3-fourths of the data segments were excluded. For models using a fixed length single-segment of observed data, the older the age covered by the corresponding data segment, the higher the resulting Rs. Logistic growth models describe age-specific incidence rates perfectly for most cancers and may be used to inform data collection for purposes of monitoring and analyzing cancer epidemic. Helped by appropriate logistic growth equations, the work vomume of contemporary data collection, e.g., cancer registry and surveilance systems, may be reduced substantially.

Energy-Saving, the Social Responsibility of the Surface Engineering Corporations

Fan Jing-Xing(번경성) 한국표면공학회 2009 한국표면공학회 학술발표회 초록집 Vol.2009 No.-

This paper introduces the energy conservation of energy management laws and regulations, trade associations in the role of energy conservation, surface engineering enterprises to energy-saving mission, and actively promote the results of energy-saving measures.

Hepatitis B Virus DNA Negativity Acts as a Favorable Prognostic Factor in Hepatocellular Carcinoma Patients

Li, Xing,Zhong, Xiang,Chen, Zhan-Hong,Xing, Yan-Fang,Wu, Dong-Hao,Chen, Jie,Ma, Xiao-Kun,Lin, Qu,Wen, Jing-Yun,Wei, Li,Wang, Tian-Tian,Ruan, Dan-Yun,Lin, Ze-Xiao,Wu, Xiang-Yuan,Dong, Min Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: This retrospective study was aimed to investigate the efficacy of prophylactic agents in hepatocellular carcinoma (HCC) patients receiving TACE and compare the difference between lamivudine and entecavir. Materials and Methods: A consecutive series of 203 HBV-related HCC patients receiving TACE were analyzed including 91 patients given prophylactic agents. Virologic events, defined as an increase in serum HBV DNA level to more than 1 log10 IU/ml higher than the nadir level, hepatitis flares due to HBV reactivation and progression free survival (PFS) were the main endpoints. Results: Some 48 (69.6%) reached virologic response. Prophylaxis significantly reduced virologic events (8.8% vs 58.0%, p=0.000) and hepatitis flares (1.1% vs 13.4%, p=0.001). Patients presenting undetectable HBV DNA levels displayed a significantly improved PFS as compared to those who never achieved undetectable HBV DNA. Prophylaxis and e-antigen positivity were the only significant variables associated with virologic events. In addition, prophylaxis was the only independent protective factor for hepatitis flares. Liver cirrhosis, more cycles of TACE, HBV DNA negativity, a lower Cancer of the Liver Italian Program score, non-metastasis and no hepatitis flares were protective factors for PFS. Prophylactic lamivudine demonstrated similar efficacy as entecavir. Conclusions: Prophylactic agents are efficacious for prevention of HBV reactivation in HCC patients receiving TACE. Achievement of undetectable HBV DNA levels displayed a significant capability in improving PFS. Moreover, persistent tumor residual lesions, positive HBV DNA and hepatitis B flares might be causes of tumor progression in these patients.

Refining and Validating a Two-stage and Web-based Cancer Risk Assessment Tool for Village Doctors in China

Shen, Xing-Rong,Chai, Jing,Feng, Rui,Liu, Tong-Zhu,Tong, Gui-Xian,Cheng, Jing,Li, Kai-Chun,Xie, Shao-Yu,Shi, Yong,Wang, De-Bin Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.24

The big gap between efficacy of population level prevention and expectations due to heterogeneity and complexity of cancer etiologic factors calls for selective yet personalized interventions based on effective risk assessment. This paper documents our research protocol aimed at refining and validating a two-stage and web-based cancer risk assessment tool, from a tentative one in use by an ongoing project, capable of identifying individuals at elevated risk for one or more types of the 80% leading cancers in rural China with adequate sensitivity and specificity and featuring low cost, easy application and cultural and technical sensitivity for farmers and village doctors. The protocol adopted a modified population-based case control design using 72, 000 non-patients as controls, 2, 200 cancer patients as cases, and another 600 patients as cases for external validation. Factors taken into account comprised 8 domains including diet and nutrition, risk behaviors, family history, precancerous diseases, related medical procedures, exposure to environment hazards, mood and feelings, physical activities and anthropologic and biologic factors. Modeling stresses explored various methodologies like empirical analysis, logistic regression, neuro-network analysis, decision theory and both internal and external validation using concordance statistics, predictive values, etc..

장기적 이윤추구성향 기업의 회계투명성 및 미래 경영성과

강창수 ( Xing Jing Jing ) 충북대학교 산업경영연구소 2018 産業과 經營 Vol.31 No.2

본 연구는 장기적 이윤추구성향 기업을 정의하고 장기적 이윤추구성향 기업과 그렇지 않은 기업의 회계투명성 및 미래 경영성과의 차이를 비교하는 것으로 목적으로 하였다. 이러한 연구목적을 달성하기 위해 2006년부터 2015년까지 한국 상장기업의 재무자료를 이용하여 이익수준 및 이익변동의 분포에서의 비연속성(discontinuity)이 발생하는 구간에서 장기적 이윤추구성향 기업을 정의하였다. 구체적으로는 이익수준 차원에서는 적자를 회피해야 할 상황에서 이익상향조정을 시도하지 않는 기업, 이익변동 차원에서는 이익감소를 회피해야 할 상황에서 이익상향조정을 시도하지 않는 기업을 장기적 이윤추구성향 기업으로 정의하였다. 그리고 장기적 이윤추구성향 기업이 그렇지 않은 기업에 비해 재량적 발생액의 절대값으로 측정한 재무보고의 질, 즉 회계투명성이 우월할 것이라는 가설을 설정하고 이를 실증하였다. 또한 장기적 이윤추구성향 기업이 미래 경영성과 면에서도 상대적으로 우월할 것이라는 가설을 설정하고 이를 검증하였다. 본 연구의 주요 결과를 요약하면 다음과 같다. 첫째, 회계투명성 비교를 위한 가설검증에서는 이익변동 차원에서만 장기적 이윤추구성향 기업들이 그렇지 않은 기업들에 비해 회계투명성이 우월한 것으로 나타났다. 이익수준 차원에서는 두 기업집단 간 차이가 없는 것으로 나타났다. 둘째, 미래 경영성과 비교를 위한 가설검증에서는 이익변동 차원에서만 장기적 이윤추구성향 기업들의 미래 경영성과가 그렇지 않은 기업에 비해 우월한 것으로 나타났다. 이익수준차원에서는 오히려 장기적 이윤추구성향 기업들의 미래 성과가 상대적으로 하락하는 것으로 나타났다. 본 연구는 장기적 이윤추구성향을 가진 경영자에 초점을 맞추어 해당 기업의 회계투명성과 미래 경영성과를 기타 기업과 비교하였다는 점에서 경영자의 이윤추구성향에 대한 기초적 연구로서의 의의가 있다. This study aims to define long-term profit-seeking firms and compare those firms with firms not seeking long-term profit in the .accounting transparency and future performance. To this end, we identified the long-term profit-seeking firms from the discontinuity interval in each of the distributions of earnings and earnings changes using Korean listed companies from 2006 to 2015. Specifically, We defined following companies as long-term profit-seeking firms respectively : companies that do not attempt to raise their profits in a situation where the deficit should be avoided in terms of earnings, and companies that do not intend to raise earnings in a situation where they should avoid earning reduction in terms of earnings changes. And we first set and empirically tested the hypothesis that the quality of financial reporting measured by the absolute value of discretionary accruals, ie, accounting transparency, is superior to firms not seeking long-term profit. Next we set and tested hypothesis that long-term profit-seeking firms will be relatively superior in terms of future management performance. The main results of this study are summarized as follows. First, hypothesis testing for accounting transparency comparisons shows that firms with long-term profit-seeking tendencies are superior to those who do not seek long-term profits in terms of earnings changes. But in terms of earnings, there was no difference between the two groups. Second, Hypothesis test for comparison of future management performance shows that future management performance of long-term profit-seeking firms is superior to those who do not seek long-term profits in terms of earnings changes. But in terms of earings, the future performance of companies with long-term profit-seeking tendency is relatively decreased. This study is meaningful as a basic study on manager's profit-seeking tendency in that it focuses on managers with long-term profit-seeking tendency and compares the accounting transparency and future management performance with other companies.