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Lateral Structural Performance of Column Frame Layer and Dou-Gong Layer in a Timber Structure
Xian-jie Meng,Tie-ying Li,Qing-shan Yang 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.2
In this study, a 1:2 scale model of a timber building with a column frame layer and a Dou-Gong layer was fabricated according to the construction method that prevailed during the Song dynasty, China (A.D. 960–1279). Three quasi-static tests were conducted on the model under three levels of vertical loads to study the seismic response of the column frame layer and Dou-Gong layer in a timber structure. The experimental results indicated that the ultimate loading state of the timber structure was mainly controlled by the lateral displacement of the column frame layer. The hysteretic behaviour and stiffness characteristics of the column frame layer were quite similar to those of the overall structure. The stiffness of the Dou-Gong layer was much higher than that of the column frame layer, and no stiffness degradation was observed in the Dou-Gong layer. Fairly little energy was dissipated by the Dou-Gong layer; more than 80% of the structural energy dissipation that occurred was attributable to the column frame layer. Moreover, based on the deformation features of the column frame and Dou-Gong layer, a theoretical model for estimating the restoring force of the overall structure was established.
Jing, Jie-Xian,Wang, Yan,Xu, Xiao-Qin,Sun, Ting,Tian, Bao-Guo,Du, Li-Li,Zhao, Xian-Wen,Han, Cun-Zhi Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
To evaluate the value of combined detection of serum CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS for the clinical diagnosis of upper gastrointestinal tract (GIT) cancer and to analyze the efficacy of these tumor markers (TMs) in evaluating curative effects and prognosis. A total of 573 patients with upper GIT cancer between January 2004 and December 2007 were enrolled in this study. Serum levels of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were examined preoperatively and every 3 months postoperatively by ELISA. The sensitivity of CEA, CA19-9, CA24-2, AFP, CA72-4, SCC, TPA and TPS were 26.8%, 36.2%, 42.9%, 2.84%, 25.4%, 34.6%, 34.2% and 30.9%, respectively. The combined detection of CEA+CA199+CA242+CA724 had higher sensitivity and specificity in gastric cancer (GC) and cardiac cancer, while CEA+CA199+CA242+SCC was the best combination of diagnosis for esophageal cancer (EC). Elevation of preoperative CEA, CA19-9 and CA24-2, SCC and CA72-4 was significantly associated with pathological types (p<0.05) and TNM staging (p<0.05). Correlation analysis showed that CA24-2 was significantly correlated with CA19-9 (r=0.810, p<0.001). The levels of CEA, CA19-9, CA24-2, CA72-4 and SCC decreased obviously 3 months after operations. When metastasis and recurrence occurred, the levels of TMs significantly increased. On multivariate analysis, high preoperative CA72-4, CA24-2 and SCC served as prognostic factors for cardiac carcinoma, GC and EC, respectively. combined detection of CEA+CA199+CA242+SCC proved to be the most economic and practical strategy in diagnosis of EC; CEA+CA199+CA242+CA724 proved to be a better evaluation indicator for cardiac cancer and GC. CEA and CA19-9, CA24-2, CA72-4 and SCC, examined postoperatively during follow-up, were useful to find early tumor recurrence and metastasis, and evaluate prognosis. AFP, TPA and TPS have no significant value in diagnosis of patients with upper GIT cancer.
Xian Jing,Kaixuan Wang,Jieqiong Lin,Peng Liu,Yudi Kan,Xu Zheng,Jie Sun,Yingchun Li 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2019 NANO Vol.14 No.1
Slicing reference data and adaptive slicing algorithm are the key issues to find out appropriate layer thicknesses of three-dimensional (3D) microstructures with free-form surface in two photon polymerization (TPP). In the present work, an adaptive slicing method (ASM) was proposed to improve the fabricating efficiency of 3D microstructures with free-form surface in TPP microfabrication. In the proposed method, slicing reference data were obtained by intersecting a series of vertical planes with the triangular patch format along characteristic directions. Maximum acceptable chordal height played a role as judging criteria to obtain appropriate layer thicknesses. What's more, typical 3D microstructures with free-form surfaces were fabricated with uniform slicing method (USM) and the proposed ASM, respectively. The comparison results showed that the proposed method effectively improved fabricating efficiency, guaranteeing an acceptable surface quality at the same time. This work was expected to provide references for improving fabrication efficiency of complex 3D microstructures in TPP.
Novel Phage Display-Derived H5N1-Specific scFvs with Potential Use in Rapid Avian Flu Diagnosis
( Jie Wu ),( Xian Qiao Zeng ),( Hong Bin Zhang ),( Han Zhong Ni ),( Lei Pei ),( Li Rong Zou ),( Li Jun Liang ),( Xin Zhang ),( Jin Yan Lin ),( Chang Wen Ke ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.5
The highly pathogenic avian influenza A (HPAI) viruses of the H5N1 subtype infect poultry and have also been spreading to humans. Although new antiviral drugs and vaccinations can be effective, rapid detection would be more efficient to control the outbreak of infections. In this study, a phage-display library was applied to select antibody fragments for HPAI strain A/Hubei/1/2010. As a result, three clones were selected and sequenced. A hemagglutinin inhibition assay of the three scFvs revealed that none exhibited hemagglutination inhibition activity towards the H5N1 virus, yet they showed a higher binding affinity for several HPAI H5N1 strains compared with other influenza viruses. An ELISA confirmed that the HA protein was the target of the scFvs, and the results of a protein structure simulation showed that all the selected scFvs bound to the HA2 subunit of the HA protein. In conclusion, the three selected scFVs could be useful for developing a specific detection tool for the surveillance of HPAI epidemic strains.
Comparison of Carcass and Meat Quality Traits among Three Rabbit Breeds
Jie Wang,Yuan Su,Mauricio A. Elzo,Xian-Bo Jia,Shi-Yi Chen,Song-Jia Lai 한국축산식품학회 2016 한국축산식품학회지 Vol.36 No.1
The objective of this study was to compare carcass composition and meat quality traits in the longissimus dorsi and biceps femoris muscles in the Hyla, Champagne and Tianfu Black rabbit breeds. Tianfu Black rabbits had the heaviest head, skin, thoracic viscera and commercial carcass percentage (p<0.05). In addition, Tianfu Black had the highest pH0 h value, followed by the Champagne and Hyla breeds (p<0.01) in the longissimus dorsi and biceps femoris muscles. Tianfu Black had a higher a* (0 h and 24 h) than the other two breeds in both longissimus dorsi and biceps femoris muscles (p<0.05). The Hyla, Champagne, and Tianfu Black breeds showed a similar pattern of differences for meat quality traits (pH, L*, a* and b*) measured in fresh meat (0 h) and meat stored for 24 h. Hyla had the highest IMF values of the three breeds (p<0.01). The lower intramuscular fat of Tianfu Black and Champagne rabbits gives them an advantage over Hyla rabbits among most consumers seeking lean rabbit meat.
Xian-Zhi Hao,Jin-Jie Huang 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.2
The filtering fault detection problem for asynchronous switched discrete-time linear systems with modedependent average dwell time (MDADT) is investigated in this paper. A series of mode-dependent fault detection filters are designed with respect to each subsystem and are equipped with the switched system to obtain an augmented switched system. For the fact that the switching of the filter lags behind that of the subsystem frequently in actual situations, the resulting augmented switched system is consequently converted into an asynchronous augmented switched system. To guarantee the globally uniformly exponentially stability (GUES) and the H_/H∞ performance of the asynchronousfiltering fault detection system, multiple Lyapunov functional and MDADT techniques are then used. The starting instants set of the subsystem is proposed to make it more convenient to apply the MDADT technique. The sufficient conditions for the existence of the designed filter and stability of asynchronous augmented switched systems are given in terms of linear matrix inequalities (LMIs). Finally, the effectiveness of the proposed methodology is demonstrated by two examples.
THE ACCURATE FALLING DETECTION SYSTEM FOR THE ELDERLY (AFDE)
Jie Ni Dorette Ong,Huijie Zhang,Vwen Yen Alwyn Lee,Clifton Phua,Kelvin Sim,Yan Liu,Xian Zhang 국제과학영재학회 2012 APEC Youth Scientist Journal Vol.4 No.-
Statistics have shown that falls are the leading cause of accidental deaths among people over the age of 75 and 55% of all falls take place in homes with most falls occurring in the bathroom. In this research, the aim of this project is to come up with a system that is able to detect falls in the washrooms, so that immediate medical aid can be provided so as to alleviate the aftereffects of the fall. Microsoft Visio was used to map the logic of the system which was then used in the creation of the rules for the system. Drools Rules is used to create a set of rules that gets input from the sensors detecting the motions of the patients, so as to infer the activities that are ongoing in order to check for errors. With input from the sensors, the set of rules should be able to determine the activity happening and possible errors that the input could imply. Simulations of real-li (Learn Not To Fall, 2009) scenarios were carried out twice. Errors and limitations of the system were noted during the simulation to further debug and improve the rules for a more robust and efficient system.