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Transdermal Pain Palliative Agents Containing Chinese Medicinal Herbs
Jia, Wei,Gao, Wenyuan,Cui, Naiqiang,Tang, Lida,Liu, Victoria J.K.,Yang, Jianqin,Qiu, Yunpin,Su, Mingming,Yu, Xiaojia The Korean Society of Plant Biotechnology 2003 Plant molecular biology and biotechnology research Vol.5 No.1
The TCM (traditional Chinese medicine) transdermal plaster (also known as "cataplasma") are flexible adhesive patches used for treatment of any pain, resulted from arthritis, sprain and bruise, tendovaginitis, lumbar spine protrude, neuralgia, hyperosteogeny ache, abdominal discomfort and metastatic cancer, etc. This paper provides a review of the TCM transdermal agents for pain palliation and the preparation of these herbal patches.l patches.
Jia, Wei,Hua, Qingyi,Zhang, Minjun,Chen, Rui,Ji, Xiang,Wang, Bo Korea Information Processing Society 2019 Journal of information processing systems Vol.15 No.4
Mobile user interface pattern (MUIP) is a kind of structured representation of interaction design knowledge. Several studies have suggested that MUIPs are a proven solution for recurring mobile interface design problems. To facilitate MUIP selection, an effective clustering method is required to discover hidden knowledge of pattern data set. In this paper, we employ the semi-supervised kernel fuzzy c-means clustering (SSKFCM) method to cluster MUIP data. In order to improve the performance of clustering, clustering parameters are optimized by utilizing the global optimization capability of particle swarm optimization (PSO) algorithm. Since the PSO algorithm is easily trapped in local optima, a novel PSO algorithm is presented in this paper. It combines an improved intuitionistic fuzzy entropy measure and a new population search strategy to enhance the population search capability and accelerate the convergence speed. Experimental results show the effectiveness and superiority of the proposed clustering method.
( Jia Wei ),( Xiao Dan Cao ),( Sheng Min Zhou ),( Chao Chen ),( Hai Jun Yu ),( Yao Zhou ),( Ping Wang ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.8
Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis through binding to its specific receptors, which mainly occurs to VEGF receptor 2 (VEGFR-2), a kinase insert domain-containing receptor. Therefore, the disruption of VEGFR-2 signaling provides a promising therapeutic approach for the treatment of cancer by inhibiting abnormal or tumorinduced angiogenesis. To explore this potential, we expressed the catalytic domain of VEGFR- 2 (VEGFR-2-CD) as a soluble active kinase in Escherichia coli. The recombinant protein was purified and the VEGFR-2-CD activity was investigated. The obtained VEGFR-2-CD showed autophosphorylation activity and phosphate transfer activity comparable to the commercial enzyme. Furthermore, the IC50 value of known VEGFR-2 inhibitor was determined using the purified VEGFR-2-CD. These results indicated a possibility for functional and economical VEGFR-2-CD expression in E. coli to use for inhibitor screening.
Rotor Profile Design and Motion Simulation Analysis of Hydrogen Circulating Pump
Jiawei Lin,Lixin Zhang,Liang Dong,Houlin Liu,Cui Dai 한국유체기계학회 2021 International journal of fluid machinery and syste Vol.14 No.4
With the development of automotive fuel cells towards high power and high efficiency, higher requirements are put forward for the speed and boost ratio of hydrogen circulation pump, while high speed and boost ratio increase the pulsation characteristics and accelerate the aging of hydrogen fuel cells. Cam type hydrogen cycle pump has the advantages of compact structure, high efficiency under low boost ratio, and good adaptability to low temperature, so it has become an important research direction. The efficient and reasonable rotor profile design can improve the volumetric efficiency of the cam rotor pump. It can reduce the pressure pulsation and flow pulsation in the pump. The equation of multi-stage circular arc rotor profile is established according to the meshing principle of the rotor. Motion Simulation module in UG NX is employed to conduct dynamic interference detection of rotor mechanism and simulation analysis of rotor mechanism meshing motion on the rotating parts of the hydrogen circulating pump. So the angular velocity curve and meshing force change curve of the driven gear is obtained. In order to verify the rationality of rotor profile design, the meshing force is compared with the standard spur gear.
Experimental Analysis and Implementation of a Multiscale Wireless/Wired Networked Control System
Jiawei Dong,Won-jong Kim 제어·로봇·시스템학회 2014 International Journal of Control, Automation, and Vol.12 No.1
The aim of this paper is to discuss the flexibility and the performance of a multiscale wireless/wired networked control system (NCS). This NCS consists of three different types of dynamic systems (fast, medium, and slow clients) with distinct time scales. The experimental results verified the capability of the NCS to combine both the wired and wireless networks and the control capability of the NCS with various sampling periods. Compared to the original wired NCS, the average steady-state error of the fast client increased by 20% to 30% under the same conditions with the wireless NCS within the bandwidth-utilization (BU) threshold. From the analysis, the sampling period together with the BU and the number of clients will determine the time-delay and packet-loss levels and affect the stability and performance of the NCS in a complex correlated manner.
Jiawei Chen,Xiaoping Gao,Ke Zhao,Wei Wu 한국섬유공학회 2022 Fibers and polymers Vol.23 No.11
The mass ratio of curing agent to epoxy resin is one of the important factors affecting the behavior of matrix andcomposites. In this paper, the solution of curing agent to epoxy resin with different mass ratio (0.25, 0.30, 0.35 and 0.40) wasselected as matrix, quadriaxial warp-knitted fabric was selected as reinforcement, and the composites were manufactured byapplying vacuum assisted film infusion. Then the tensile and bending behavior of the composites was experimentallyinvestigated, and the curing degree and failure mechanism of the composites were analyzed with respect to thethermodynamic properties and the microscopic failure morphologies. The optimal mass ratio was obtained by applyingnonlinear fitting and verified by experiment, and a mathematical model was derived to predict the relationship between thestrength and the mass ratio. The results showed that the thermal stability, curing degree, tensile and bending strength of thespecimens increase firstly and then decrease with increase of the mass ratio. According to the tensile and bending strengthresults, the optimum mass ratio were obtained as 0.31 and 0.33 by applying nonlinear fitting to the experiment data. Theresults could lay a theoretical foundation for optimizing the mass ratio of matrix components, and improve the strength ofcomposites.
Jiawei Pang,Shenghuan Su,Qiaofeng Han 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.2
As one of the basic bismuth nitrates, Bi2O2(OH)(NO3) (denoted as BION) has been reported to exhibit powerful photodegradation activity for various contaminants. However, pure BION could only be irradiated by UV light due to broad bandgap ( ~3.14 eV). Herein, Bi2S3/Bi2O2(OH)(NO3) (denoted as BS-BION) heterojunction was prepared by an in situ ion exchange reaction between BION and aqueous thiourea solution (pH ~ 3). The resulting heterojunction possessed good visible light absorption and closely contacted interfaces, which benefited effective separation and transfer of photogenerated charges, thus leading to excellent photocatalytic activity for the degradation of rhodamine B (RhB) under visible light irradiation. Furthermore, the as-prepared heterojunction photocatalyst also presented high photochemical stability, which may be of great significance for practical application.
Experimental nonlinear vibrations of an MRE sandwich plate
Jiawei Zhang,Tanju Yildirim,Gursel Alici,Shiwu Zhang,Weihua Li 국제구조공학회 2018 Smart Structures and Systems, An International Jou Vol.22 No.1
The nonlinear vibration analysis of a magneto-rheological elastomer (MRE) sandwich plate is conducted experimentally. Experiments have been performed in order to construct the frequency-response curves in the vicinity of the fundamental natural frequency of an MRE sandwich plate (plate A) in either the absence or presence of a localised external magnetic field at 3 different geometrical locations, for both small and medium magnetic fields. Furthermore, experiments have also been conducted on a pure aluminium plate (plate B) with an equal thickness to the MRE sandwich plate (plate A) in order to examine the influence of the MRE layer on the nonlinear dynamics of the system. An electrodynamic shaker was used to directly force each system and the displacement at the centre of the plate was measured. Meanwhile, permanent magnets were used to apply a localised magnetic field for the experiments where the MRE sandwich plate was subject to an external magnetic field. It was observed all the MRE systems displayed strong hardening-type nonlinear behaviour, however, with increasing magnetic field this behaviour transitioned to a weak hardening-type nonlinearity.
A new method to detect cracks in plate-like structures with though-thickness cracks
Jiawei Xiang,Yongying Jiang,Udo Nackenhorst,Yanxue Wang,Haifeng Gao,Yumin He 국제구조공학회 2014 Smart Structures and Systems, An International Jou Vol.14 No.3
In this paper, a simple two-step method for structural vibration-based health monitoring for beam-like structures have been extended to plate-like structures with though-thickness cracks. Crack locations and severities of plate-like structures are detected using a hybrid approach. The interval wavelet transform is employed to extract crack singularity locations from mode shape and support vector regression (SVR) is applied to predict crack serviettes form crack severity detection database (the relationship of natural frequencies and crack serviettes) using several natural frequencies as inputs. Of particular interest is the natural frequencies estimation for cracked plate-like structures using Rayleigh quotient. Only the natural frequencies and mode shapes of intact structures are needed to calculate the natural frequencies of cracked plate-like structures using a simple formula. The crack severity detection database can be easily obtained with this formula. The hybrid method is investigated using numerical simulation and its validity of the usage of interval wavelet transform and SVR are addressed.