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      • KCI등재

        DFT Studies on Two Novel Explosives Based on the Guanidine-Fused Bicyclic Structure

        Xing-Hui Ji,Bing-Cheng Hu,Huan-Qing Jia,Zu Liang Liu,Chun-Xu Lu 대한화학회 2014 Bulletin of the Korean Chemical Society Vol.35 No.4

        Density functional theory (DFT) calculations at the B3LYP/6-31G(d,p) theoretical level were performed for two novel explosives (compounds B and C) based on the guanidine-fused bicyclic skeleton C4N6H8 (A). The heats of formation (HOFs) were calculated via isodesmic reaction. The detonation properties were evaluated by using the Kamlet-Jacobs equations. The bond dissociation energies (BDEs) for the thermolysis initiation bond were also analyzed to investigate the thermal stability. The results show that the compounds have high positive HOF values (B, 1064.68 kJ·mol−1; C, 724.02 kJ·mol−1), high detonation properties (ρ, D and P values of 2.04 g·cm−3 and 2.21 g·cm−3, 9.98 km·s−1 and 10.99 km·s−1, 46.44 GPa and 59.91 Gpa, respectively) and meet the basic stability requirement. Additionally, feasible synthetic routes of the these high energy density compounds (HEDCs) were also proposed via retrosynthetic analysis.

      • KCI등재

        Mutations in AP22.65 Accelerate Flowering in Arabidopsis thaliana

        Ji Hong Xing,Feng Ru Wang,Jiao Jia,Jing Zhang,Li Li,Zhan Chen,Qiao Yun Weng,Ping Yang,Ye Zhang,Bin Zhao,He Long Si,Jin Gao Dong,Jian Min Han 한국식물학회 2013 Journal of Plant Biology Vol.56 No.1

        Identification of the gene(s) responsible for floweringtime in Arabidopsis has significant implications. We used theT-DNA insertion library of Arabidopsis thaliana to screen anearly-flowering mutant that exhibits accelerated floweringunder short-day conditions. AP22.65, a novel flowering-timegene in that species, was isolated and identified via genomewalkingand bioinformatics analysis. The flowering time ofAP22.65-complementing plants was similar to that of theCol-0 wild type (WT). Conversely, its overexpression delayedflowering. Consistent with this phenotype, expression ofAP22.65 was decreased in the ap22.65-1 mutant, recoveredin AP22.65-complementing plants, and increased in AP22.65-overexpressing plants. Compared with the WT, expressionlevels of critical genes in different flowering pathways, i.e.,SPY, FLC, GI, CO, FT, and LFY, were down-regulated inloss-of-function mutants. Expression of AP22.65 was distributedin flowers, siliques, rosette leaves, and whole seedlings. Therefore, this gene may be a negative regulator of Arabidopsisflowering.

      • SSCISCOPUSKCI등재

        The Diaoyudao (Senkaku) Disputes and Prospects for Settlement

        ( Ji Guo Xing ) 한국국방연구원 1994 The Korean Journal of Defense Analysis Vol.6 No.2

        The Diaoyudao (Senkaku) disputes between China and Japan are one of the most controversial issues in Northeast Asia, The controversy involves two dimensions: sovereignty over the Diaoyudao Islands and the relevant maritime jurisdictional rights and interests in East China Sea. China holds that the Diaoyudao Islands have been China`s territory since ancient times, and that they appertain to Taiwan. China argues that from the viewpoints of geography, history, usage, and international treaties, the Islands belong to China. Japan holds that these Islands were terra nullius before their incorporation by Japan in 1895, and that they were not included in the Shimonoseki Treaty signed after the Sino- Japanese War in 1895, nor included in the territories Japan had to give up according to the San Francisco Peace Treaty of 1951. Judging from international law, the claims of China are valid and well-founded, and are stronger than those of Japan. First, China meets the requirements of acquisition by discovery. Secondly, Japan`s annex- ation of the islands is closely related to its victory in the Sino-Japanese War, and this annexation has no legal effects on sovereignty. Thirdly, the inclusion of the Islands in the Okinawa Reversion Treaty signed between Japan and the US in 1971 cannot be taken as an evidence of Japan`s sovereignty over the Islands. The disputes over the Diaoyudao Islands are in fact greatly connected with relevant maritime jurisdictional rights and interests. There exist differences between China and Japan in regard to the principles of the delimitation of continental shelf, to the maritime jurisdictional rights of isJands, and to the principles of boundary delimitation. China adheres to the natural prolongation of land territory, and holds that the Diaoyudao islands do not warrant their own continental shelf, and that the boundary delimitation should be mainly effected by agreement. Japan stands for a 200-nautical-miles limit for the continental shelf, for the use of the Islands as base points for continental shelf claims on East China Sea, and for the median-line principle in boundary delimitation. The Diaoyudao disputes have been shelved since the normalization of relations between China and Japan in 1972-a good approach, but it was only an expedient measure. Now the conditions for negotiated solutions are gradually coming to maturity. There might be three options for the settlement. The first would be to come to an agreement on boundary delimitation through negotiation in a spirit of mutual understanding and mutual accomodation. The second one is to agree to put this issue to the International Court of Justice for arbitration or to accept other forms of third-party involve- ment. The third would be to work for joint development in the disputed areas. The sea areas around the Diaoyudao Islands seem of low prospect in oil and gas reserves, but the sea areas near the Islands and on the disputed relevant continental shelf do have good prospects. The third option looks to be the most feasible approach at present.

      • KCI등재

        On the hydraulic axial thrust of Francis hydro-turbine

        Xing-Ying Ji,Xiao-Bin Li,Wen-Tao Su,Xu Lai,Tian-Xiao Zhao 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.5

        We present a new method for the computation of hydraulic axial thrust of Francis hydro-turbine. This approach combines the computation of axial thrust on the crown, band and blade by using the numerical simulation and calculation of the pressure distribution outside the crown and band based on the theory of fluid mechanics. The axial thrusts are calculated for different flow conditions with various suction head and flow rate. The calculated results are consistent with that of experimental test on the prototype hydro-turbine, and this combination is proven to be an effective way to assess the magnitude of hydraulic axial thrust for hydro-turbine. Also, the suction head of the turbine is shown to have significant influence on the hydraulic axial thrust.

      • Amycolatopsis jiangsuensis sp. nov., a novel endophytic actinomycete isolated from a coastal plant in Jiangsu, China.

        Xing, Ke,Liu, Wei,Zhang, Yue-Ji,Bian, Guang-Kai,Zhang, Wen-Di,Tamura, Tomohiko,Lee, Jung-Sook,Qin, Sheng,Jiang, Ji-Hong N.V. Swets en Zeitlinger 2013 Antonie van Leeuwenhoek Vol.103 No.2

        <P>A novel actinomycete, designated strain KLBMP 1262(T), was isolated from a coastal plant Dendranthema indicum (Linn.) Des Moul collected from the coastal region of Nantong, Jiangsu Province, in east China and was studied in detail for its taxonomic position. Phylogenetic analysis based on the 16S rRNA gene sequence revealed that strain KLBMP 1262(T) is a member of the genus Amycolatopsis. The 16S rRNA gene sequence similarity indicated that strain KLBMP 1262(T) is most closely related to Amycolatopsis sulphurea DSM 46092(T) (97.96 %), Amycolatopsis ultiminotia RP-AC36(T) (97.50 %) and Amycolatopsis jejuensis N7-3(T) (97.44 %); similarity to other type strains of the genus Amycolatopsis was less than 97.0 %. The organism was determined to have chemical and morphological features consistent with its classification in the genus Amycolatopsis such as meso-diaminopimelic acid as the diagnostic diamino acid in the cell wall peptidoglycan and arabinose and galactose as the diagnostic sugars. The predominant menaquinone was determined to be MK-9 (H(4)). The polar lipids detected were phosphatidylmethylethanolamine, phosphatidylethanolamine, an unknown aminophospholipid, two unknown glycolipids and several unknown lipids. The major fatty acids were found to be C(16:0), iso-C(16:0) and iso-C(15:0). DNA-DNA relatedness data, together with phenotypic differences, clearly distinguished the isolate from its closest relatives. On the basis of these phenotypic and genotypic data, the isolate is considered to represent a novel species, for which the name A. jiangsuensis sp. nov. is proposed. The type strain is KLBMP 1262(T) (=KCTC 19885 (T) = NBRC 108679(T)).</P>

      • MiR-34b/c rs4938723 Polymorphism Significantly Decreases the Risk of Digestive Tract Cancer: Meta-analysis

        Ji, Tian-Xing,Zhi, Cheng,Guo, Xue-Guang,Zhou, Qiang,Wang, Guo-Qiang,Chen, Bo,Ma, Fei-Fei Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

        Background: Previous studies investigating the association between miR-34b/c rs4938723 polymorphism and cancer risk showed inconclusive. Here, we performed meta-analysis to investigate the association between miR- 34b/c rs4938723 polymorphism and digestive cancer risk. Materials and Methods: Literature database including PubMed, OVID, Chinese National Knowledge Infrastructure (CNKI) were searched for publications concerning the association between the miR-34b/c rs4938723 polymorphism and digestive cancer risk. Results: A total of 6 studies consisting of 3246 cases and 3568 controls were included in this meta-analysis. The combined analysis suggested the miR-34b/c rs4938723 polymorphism significantly reduced digestive cancer risk under allelic model, homogeneous co-dominant model and recessive model (C vs T: OR=0.88, 95%CI=0.82-0.95, p-value=0.001; CC vs TT: OR =0.67, 95%CI=0.57-0.80, p-value=0.000; CC vs TT/TC: OR=0.68, 95%CI=0.58-0.80, p-value=0.000). Q-test and I2 test revealed no significant heterogeneity in all genotype comparisons. The Begger's funnel plot and Egger's test did not show significant publication bias. Conclusions: The current evidence supports the conclusion that the miR-34b/c rs4938723 polymorphism decreases an individual's susceptibility to digestive cancers.

      • KCI등재

        Prevention of UV-Induced Skin Damages by 11,14,17-Eicosatrienoic Acid in Hairless Mice In Vivo

        Xing-Ji Jin,김은주,오인경,김연경,박치현,정진호 대한의학회 2010 Journal of Korean medical science Vol.25 No.6

        Polyunsaturated fatty acids (PUFAs) are known to play important roles in various physiological and pathological processes. Recent studies have shown that some omega-3 (w-3) PUFAs, such as eicosapentaenoic acid (EPA) and dodecahexaenoic acid (DHA), have protective effects on acute and chronic UV-induced changes. However,the effects of other w-3 PUFAs including 11,14,17-eicosatrienoic acid (20:3)(ETA) on UV-induced skin damages are poorly understood. In this study, we investigated the cutaneous photoprotective effects of ETA in hairless mice in vivo. Female HR-1 hairless mice were topically treated with vehicle (ethanol:polyethylene glycol=30:70) only, 0.1% ETA, or 1% ETA once a day for 3 successive days after one time UV irradiation (200 mJ/cm2) on dorsal skins. Skin biopsy was carried out on the fourth day (72 hr after UV irradiation). We found that topical treatment with ETA attenuated UV-induced epidermal and dermal thickness and infiltration of inflammatory cells,and impairment of skin barrier function. In addition, ETA suppressed the expression of IL-1b, COX-2, and MMP-13 induced by UV irradiation. Our results show that the topical application of ETA protects against UV-induced skin damage in hairless mice and suggest that ETA can be a potential agent for preventing and/or treating UVinduced inflammation and photoaging.

      • SSCISCOPUSKCI등재

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