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      • KCI등재

        가감청영탕(加減淸營湯)에 효과를 보인 열성 아토피 피부염 환자 6례 증례 보고

        서지혜,정창환,박선정,임소영,한수련,Seo, Ji-Hye,Jung, Chang?Hwan,Park, Seon-Jeong,Lim, So-Young,Han, Su-Ryun 대한한방안이비인후피부과학회 2014 한방안이비인후피부과학회지 Vol.27 No.3

        Objective : The purpose of this study is to investigate the effect of Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) for atopic dermatitis patients diagnosed as the febrile tendency. Method : This case study was done on 6 atopic patients with febrile tendency who have visited Korean Medicine Clinic from 2013.08.01. to 2014.04.30.. Gagamchengyoung-tang($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) was prescribed to all 6 patients and evaluated the symptom change through photographs and questionnaire. Objective SCORAD Index(OSI) was used to evaluate the objective symptom and VAS was used to evaluate the subjective change. Results & Conclusion : The Objective SCORAD index and VAS were decreased in all patients. The average OSI reduction score was 26.3. Most symptoms of 6 patients were improved. Gagamchengyoung-tang ($Ji\bar{a}ji\check{a}nq\bar{i}ngy\acute{i}ng-t\bar{a}ng$) can be effective in patients who were diagnosed as febrile tendency.

      • KCI등재

        3,4‑Dichloroaniline promotes fatty liver in zebrafish larvae

        JiSeon Park,송정아,Jong‑Su Park,이상우,Jieon Lee,Han‑Jin Park,Woo‑Keun Kim,Seokjoo Yoon,Hang‑Suk Chun 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.2

        Backgrounds 3,4-Dichloroaniline (3,4-DCA) is a transformation product of herbicides that is commonly used as a reference in developmental toxicity studies (OECD TG 236) (Bonnet et al. in Environ Toxicol 22:78–91, 2007). However, the mechanisms underlying 3,4-DCA-induced hepatotoxicity are not well known. Methods We exposed zebrafish larvae at 72 hpf to 3,4-DCA for 3 days and observed lipid accumulation in liver treated with 10-μM 3,4-DCA using oil red O staining. Subsequently, we performed qRT-PCR analysis to determine the genes involved in the observed lipid accumulation. Results We found that genes related to lipogenesis (srebp1, pparγ, lipin1, and scd1) and ER stress (bip, atf4, ddit3, dnajc3, and edem1) were significantly upregulated. In addition, we found that ROS generation increased in the larvae treated with 10-μM 3,4-DCA. Moreover, glutathione-S-transferase activity in these larvae was increased by 3,4-DCA in a dose-dependent manner, and the expression of the inflammation marker il-1β increased. Conclusion Our results indicated that exposure to 3,4-DCA induced fatty liver in zebrafish larvae and that this, in association with additional factors such as ER stress response, can promote liver damage. We accordingly suggest that 3,4-DCA could be used to induce fatty liver in zebrafish larvae.

      • KCI등재

        Influence of Gas Nitriding on the Damping Capacity of Fe‑17Mn Alloy

        Seon‑Min Choi,Ji‑Sook Park,Kyongjun An,이영국 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.1

        Fe-17Mn alloy has been attracted as a high damping alloy due to its excellent damping capacity and tensile properties. For itsindustrial application, it is necessary to improve both wear resistance and anti-oxidation. To solve this problem, gas nitridingwas performed at 520 °C for 10 h using cold-rolled specimens. The nitrided specimen revealed a thick nitride layer of~ 68 μm with ~ 20%Mn and a hardness value of ~ 650 Hv on the matrix of ε martensite and γ austenite without the diffusionlayer. The damping capacity of the nitrided specimen was decreased with increasing the thickness ratio of nitride layer tomatrix. However, when the thickness ratio was ≤ 1.5%, the damping capacity of the nitrided specimen was similar to that ofthe nitride-free specimen. This indicates that the wear resistance and anti-oxidation of Fe-17Mn alloy can be improved bya thin nitride layer without the loss of its damping capacity.

      • KCI등재

        연결어미 ‘-든지’의 통사 · 의미적 특징

        목지선(Mok, Ji-seon) 한국어문학회 2017 語文學 Vol.0 No.136

        The ending ‘-deunji’ is divided into single construction and reduplication construction based on the number of proposition combined. It may be used as a final ending, connective ending, or ending of embedded sentence in terms of the presence or types of following elements. This study examines various usage of ‘-deunji’ particularly in a form of the reduplication construction such as ‘-deunji, -deunji’ and analyzes its syntactic and semantic characteristics. First, the primary condition of using ‘-deunji’ is the availability of the list of items for selection, and therefore the ending does not merely require the performance of selection. This may be supported by the fact that ‘-deunji’ is often employed in the reduplication construction to represent the meaninglessness of selection, and that it also appears in a form of ‘infinitival construction + -deunji.’ On the other hand, the form of ‘proposition + -deunji’ contains a semantic feature so that it can be repeated as ‘ending 1, ending 2, ....., ending n + following phrase,’ when the range or standard of selection is decided by the characteristics of the following phrase. However, it is difficult to conclude that the preceding endings merely function to enumerate items, while the last ‘ending n’ has a distinct function. According to this study, the reduplication construction of ‘-deunji, –deunji’ can be divided into ‘-deunji -deunji + following phrase’ and ‘-deunji -deunji + hada.’ First of all, the form of ‘-deunji -deunji + following phrase’ can be sub-categorized in accordance with the presence of the expression that characterizes the listed objects in the following phrase. In the form where the reduplication construction of ‘-deunji’ is followed by the phrase, the necessity of selection varies depending on the proposition in the phrase. The use of the form depends on the necessity of selection, and the form can be distinguished by the way in which the followed expression imposes limitation on the ‘-deunji’ phrase. In this respect, this article argues that ‘-deunji -deunji + following phrase’ has three types in regard to the openness of proposition list and the necessity of selection: extreme openness, semi-openness, and closeness. The first type is conditioned by the complete absence of the following phrase expression that intends to define the category or characteristics of the listed proposition. In this case, the reliability of the former “deunji” statement does not affect the meaning of following phrase, and other objects can be listed as many as the speaker wants, so it shows the extreme openness. The second type is used when the expression that defines the category or selection criteria of listed propositions is followed by the phrase that contains semi-openness in the followed expression. This type can be divided again based on whether or not the followed phrase or noun (phrase) presents the selection criteria that characterizes the listed objects. The latter pattern is often used when the speaker only intends to provide a list of objects. Lastly, the third type is the expression that put a limit on the number of listed propositions and selections in the following phrase, and it therefore represents the closeness of listed objects. Therefore, the pattern of extreme openness does not demand the listener’s act of selection, while that of semi-openness and closeness requires the performance of selection.

      • 문헌정보학 교과과정의 비교·분석

        김지선 충남대학교 사회과학대학 문헌정보학과 1997 文獻情報學論集 Vol.7 No.-

        The purpose of this study is to analyze change process by means of curriculum in library & information science and to compare curriculum change of each college. For this study, It collect library & information science curriculum from manual of each colleges from 1975 to 1995. Since Yonsei University was established in 1957, Library & information science in university has been established thirty-two University by 1995. The number of established curriculum is increased respond to current of time and advantage of knowledge. Mnasory area, management area of NATIS program is analyzied. Each university is similar to curriculum and the number of courses. Therefore, this study provied as with the same advice as follows: Mansory area should include Research method of library & information science course, Massmedia and society course, Archive Preservation course. Management area should include Library Policy course, Finance and Personal Management course, Electronic Library. Material are should include Manangement of Archives course, Collection Development course, Special Subject Material course.

      • KCI등재

        병원건축 길찾기 요소의 중요도 분석에 관한 연구 : 'A'종합병원 외래진료부를 중심으로

        윤지선,박재승 한국의료복지시설학회 2008 의료·복지 건축 Vol.14 No.3

        Upon reviewing the tendency of the large-scale hospital buildings constructed so far, we may well know that the architectural space of the hospital buildings has been designed for users' conveniences in terms of functional elements fulfilled, efficiency, uniform colors and lighting, which means that patients may well feel difficult to find their ways in the hospital. The result may be that the patients who are weak mentally and physically feel uneasy or tensed when they wander in the hospital, which may lead to their increased physical fatigue, higher blood pressure or other harmful effects. Thus, patients' way-finding emerges as a new design challenge for the hospital building. The purpose of this study was to define the environmental variables and factors affecting patients' way-finding in the hospital and thereby, determine the correlations between the variables/factors and way-finding to provide for some framework of analysis useful to solutions of patients' way-finding problems, while identifying the causes for difficulty of their way-finding due to differences of perception between hospital building designer and user groups.

      • 자질유인이론적 접근에 따른 양화사 인상

        김지숙,양선기 순천대학교 어학연구소 1999 어학연구 Vol.10 No.-

        This paper aims to examine how to account for the difference between ambiguity and unambiguity of the scope shown in the quantifier structure. To distinguish ambiguity from unambiguity of scope by raising quantifier, we examine the data presented in Aoun & Li (1989), Aoun & Li (1993), and Pica & synder 91994). Finally, we will try to capture scope analysis by the quantifier raising in English under the Attract-F, minimalist framework. The paper is organized as follows. Section Ⅱ discusses the so - called quantifier raising as α-movement. In section Ⅲ we examine Aoun & Li's(1993) approach to the quantifier raising under economy principle. In section Ⅳ we treat the quantifier raising in terms of the Chain and Case assignment. The tentative results emerging from the minimalist framework, Attract-F theory on the quantifier raising are summarized in section Ⅴ and Ⅵ.

      • KCI등재

        빈랑자 추출물의 염색성 및 기능성에 관한 연구

        김지선,조용석,최순화 대한가정학회 2003 Family and Environment Research Vol.41 No.7

        Recently there has been interested in the use of natural dyes in textile applications. Generally natural dyes can exhibit better biodegradability and have a higher compatibility with the environment. In this study, cotton wool and silk fabrics were dyed with alkali extract of Arecae semen using various mordants, and their dyeabilities were discussed. Additionally the fastness to washing, perspiration, light, rubbing, and drycleaning and UV-B protection rate were also investigated. Cotton, silk and wool fabrics dyed with alkali extract of Arecae semen were colored in reddish yellow tint. The optimum dyeing condition of the colorants extracted from the Arecae semen was three repeated dyeing at 95℃ for 1.5hrs. The dyed fabrics by using mordanting methods improved the fastness to washing, perspiration and drycleaning, but the fastness to light and rubbing were not increased. The UV-B protection rate of the wool fabrics were increased by dyeing with extract of Arecae semen.

      • 반월형 공기음영(air-meniscus sign)을 보인 폐 경화성 혈관종 1례 : A Case Report

        정선관,노지영,노병석,원종진 圓光大學校 醫科學硏究所 1998 圓光醫科學 Vol.14 No.1

        Sclerosing hemangiomas which uncommonly occur in the pulmonary parenchyma rarely have the air-meniscus sign on the radiologic examinations. We report a case of histopathologically proven sclerosing hemangioma with the air-meniscus sign of the lung on both chest radiograph and CT.

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