韓牛肉의 筋漿蛋白質 및 筋原纖維蛋白質에 대한 加熱處理의 影響(Ⅰ)

河淨昱 건국대학교 1983 論文集 Vol.17 No.1

Heat-induced changes in sarcoplasmic and myofibrillar proteins were studied in samples of 24 hour-postmortem bovine longissimus muscle and semitendinosus muscle heated at 45℃, 55℃, 70℃, respectively. Sarcoplasmic proteins were extracted with 0.25M sucrose buffer solution (pH7.6) and myofibrillar proteins were extracted with 0.6M KCl buffer solution (pH 7.4). The extractability of sarcoplasmic and myofibrillar proteins of longissimus muscle was higher than that of semitendinosus muscle, and the amount of extracted proteins decresed sharply as the heating temperature changed. Consequently, the extracted amount of sarcoplasmic proteins was 220.8mg, 196.8mg, 189.6mg, and 166.8mg from longissimus muscle, and 226.8mg, 189.6mg, 160.8mg and 120.0mg from semitendinosus muscle. And myofibrillar proteins, which were extracted by 0.6M KCl buffer solution, were 94.0mg, 61.0mg, 61.0mg, 30.0mg from loagissimus muscle, and 69.0mg, 59.0mg, 38.0 mg and 30.0mg from semitendinosus muscle, respectively. Molecular changes in sarcoplasmic proteins and myofibrillar proteins were characterized using 7.5% SDS-polyacrylamide gel electrophoresis. The 200,000 dalton component, which appeared in the sarcoplasmic protein electrophore-togram of unheated samples, seemed to be a decomposed residue of heavy meromyosin. The 200,000 dalton component disappeared in the 55℃ treated samples. And the 100,000 dalton component was found in 45℃ and 55℃ treated samples. The proteins of thick filament, thin filament and Z-disks of myofibrils reacted differently to heating. Alpha-actinin was the most labile component and became coagulable at 55℃. Heavy and light chains of myosin became insoluble at 55℃. Actin, tropomysin and troponin were heat resistant, but they became insoluble at 70℃. The 30,000 dalton component, a decomposed component of Troponin T, could not be found in the electrophoretograms of two proteins.

기종성 신우신염 1례

이재욱,구정태,서정일,양창헌,이정호,이동철,이영현,이활,이경섭 동국대학교 경주대학 1997 東國論集 Vol.16 No.1

기종성 신우신염은 주로 당뇨병환자나 폐쇄성 요로질환을 가진 환자에 발생하며 특징적으로 신실질 및 그 주위조직에 가스를 형성하면서 심한 조직괴사를 일으키는 매우 드문 급성 화농성 신감염으로 사망률이 높은 질환이다. 이 질환은 1989년 Kelly와 MacCallum에 의해 처음 보고된 이래 외국문헌에 약 90례 정도가 보고되어 있으며 국내에는 28례가 보고되어 있다. 수액 및 전해질 보충, 인슐린 투여를 통한 적절한 혈당조절 및 항생제 투여등의 내과적 치료와 절개배농 및 신적출술등의 수술적 치료 방법이 있다. 내과적 치료로 가스의 감소가 없는 경우에는 즉각적인 수술적 치료를 시행하여야하므로 이 가스변화에 대한 추적관찰이 중요하다 하겠다. 본 저자들은 당뇨병환자에서 발생한 기종성 신우신염 1례를 내과적 요법을 치험하였기에 문헌고찰과 함께 보고하고자 한다. Emphysematous pyelonephritis is rare, life-threatening infection of the renal parenchyma and perirenal tisseue. This disease is characterized by the production of intrarenal and perirenal gas and is frequently encountered in patients with diabetes mellitus or urinary obstruction. We experienced a case of emphysematouse pyelonephritis in a 62 years old women with poorly controlled diabetes mellitus who had been managed with medical theraphy. So we report this case with a review of the referenced literatures.

노인에서 정서 인식의 저하

이경욱,채정호,최인철,이해국,권용실,이정태 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2

Objectives : The purpose of this study was to investigate whether elderly and young adults differ in their recognition of facial expressions of emotion. Methods : A total of 120 (elderly group 53, young group 67) subjects participated in this study. Korean facial expressions of emotion including happiness, sadness, fear, anger, disgust, surprise and neutral were used as stimuli for facial affect recognition test. Computerized facial affect recognition test that consists of facial affect discrimination test and facial affect intensity test was performed. Results : For facial affect discrimination test, there was a significant difference between two groups (F==3.986, P<.01) after controlling the effect of education. Elderly participants showed significantly less correct recognition rate with sadness, anger and disgust (p<.05). For facial affect intensity test, there was no significant difference between the groups in recognition of emotional intensity. Chi-square test or t-test was done according to the clinical variables. Multivariate analysis of covahance was done to test group differences of correct recognition rate and emotional intensity. Conclusion : This is the first report of differential decrease of facial affect recognition in elderly using Korean facial expressions. This study suggests that the decrement of facial affect recognition maye be a part of normal aging process.

전자 디스펜서용 단일칩 제어기 설계

원영욱,김정범 강원대학교 정보통신연구소 2005 정보통신논문지 Vol.9 No.-

The electronic dispenser is composed of electronic part and mechanical part. Electronic part is consisted of input keypad, micro-controller, display module, and pump module. In this paper we designed micro-controller for electronic part. The micro-controller controls display module and pump module. The display module is composed by LCD device, and the pump module is composed by motor device. The micro-controller for an electronic dispenser is designed by VHDL. We used WX12864AP1 for the LCD device and SPS 20 for the stepping motor. Also, the micro-controller is designed by Altera Quartus tool and verified with Agent 2000 Design-kit using APEX20K Device. In this paper, we present possibility to adopt of biotechnology field through designing of one-chip controller for an electronic dispenser.

응급실 내원시 예상치 못한 사망 환자의 예측 인자

김욱진,서정필,정성필,황태식,이한식 대한응급의학회 1998 대한응급의학회지 Vol.9 No.4

Background: Unexpected deaths of the patients at ED are surprising to the medical staffs as well as the families. It may also increase the possibilities of medico-legal problems. This study was conducted to review the unexpected death in ED and find the predictive factors leading patients to unexpected death. Methods: A retrospective study with reviewing available medical records of 183 patients who were expired at Ed of Shinchon Severance Hospital from Mar. 1997 to Feb. 1998 and 103 patients of Youngdong Severance Hospital from Mar. 1996 to Feb. 1998 was done. Analyses were done on 30 variables of physical findings, laboratory results, procedures and therapies. We used univariate analysis such as t-test and x²-test and multiple logistic regression analysis. Results: Of the total 286 deaths in Ed, 153 cases were enrolled in this analysis. The number of unexpected deaths were 76. Age, mental status, fraction of neutrophil count, BUN level, whether endotracheal intubation was done, use of inotropics were the factors with statistical significance on the univariate analysis, but only comatose mentality, endotracheal intubated case, and use of the inotropics were significant on logistic regression analysis. The longer the ED length of stay, the higher the rate of mortality and unexpected death. Conclusion: This result suggest that medical attention is needed on the patients with comatose decreased mental status, endotracheally intubated case and needing inotropic agents to prevent unexpected deaths shortening the ED length of stay may also be a factor for decrease the unexpected death rate.

국산밀과 수입밀의 이화학적 특성

하정욱,이승철 慶南大學校 附設 基礎科學硏究所 1997 硏究論文集 Vol.11 No.-

To compare chemical characteristics of domestic wheat flour and imported one. we determined moisture. crude protein, ash, and crude lipid. In the case of moisture content, domestic crude wheat flour has shown 10.84%, the lowest value. while that of imported wheat flour has shown 13.33∼14.19%. In crude protein content, domestic fine wheat flour shown 11.69%. and domestic crude has shown 14.34%, while that of imported strong, medium, weak wheat flour has shown 14.30, 11.78, and 9.28%, respectively. In ash content. domestic crude wheat flour has shown 1.50%, and that of domestic fine one has shown 0.74%, while that of imported one has shown 9.85~11.12%. In color analysis. domestic fine wheat flour has shown similar lightness as that of imported strong wheat flour.

40세 이하 관상동맥 질환자에서 장기적 임상 관찰

이승욱,정명호,박종철,박형욱,조상희,김원,김계훈,이상현,강경태,조장현,김남호,김건형,안영근,조정관,박종춘,강정채 全南大醫大 2001 전남의대학술지 Vol.37 No.2

정신분열병에서 TAP2 유전자의 다형성

송정민,전태연,이경욱,배치운,표철우 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.3

경수 손상의 임상적 분석

김정수,강재규,도종웅,김기욱,김상진 최신의학사 1991 最新醫學 Vol.34 No.1

PDMS-PU 탄성체의 합성과 물성 및 Zwitterionization에 관한 연구

윤정욱,왕은진,백남철 慶熙大學校 材料科學技術硏究所 1992 材料科學技術硏究論集 Vol.5 No.-

The mechanical properties of polyurethane elastomer synthesized from hydroxybutyl-terminated polydimethylsiloxane(PDMS) of molecular weight 1000 and 4,4'-methylene diphenyldiisocyanate(MDI) were investigated. Hard segment content varied from 33% to 56% and various chain extender with 1,4-butanediol(BD), N-methyldiethanolamine(MDEA) or ethylene diamine(ED) were used in the segmented polyurethane block copolymer. The MDEA-extended materials were zwitterionized by using 1,3-propane sultone. By using gel permeation chromatography, infrared spectroscopy, differential scanning calorimetry and universal tensile Testing machine, physical and thermal properties of these polymers were investigated. All of these polyurethane elastomer showed phase separation. BD-extended material shows a higher tensile strength for the higher hard segment content material. MDEA-extended materials which were ionized by 1,3-PS exhibited better tensile properties than un-ionized copolymer. The zwitterionomer material exhibited ionic aggregation within the hard domain. Hard domain cohesion was found to be a important factor in determining the tensile properties of the elastomers.