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하이퍼미디어 시스템 탐색의 최적 스케쥴을 찾는 통계적 페트리 넷을 이용한 새로운 패러다임
임재걸,변정용 동국대학교 경주대학 1997 東國論集 Vol.16 No.1
Information providers on WWW have comprehensive meta-knowledge of their information: For each data unit, they know the size of data, time needed to read, the subject of the data, the objective value of the data, how close it is to the original information, and so on. With this comprehensive meta-knowledge, an information provider can find an optimal schedule of information exploration for the users. A schedule is a sequence of hypermedia scenarios,where as a hypermedia scenario is a sequence of hyperlinked multimedia data units. A schedule is legal if the schedule can be finished within a given time. A legal schedule is optimal if it gives the maximum satisfaction to the user. This paper proposes a new paradigm to find such an optimal schedule. We assume that the data units are graded on certain criteria. For example, a piece of data is about an architectural "national treasure" whereas another one is about a "general treasure". With this grades and the degree of closeness to the original information, we can get the degree of potential user's satisfaction. Now, we need the time required to finish a hypermedia scenario. As a method to find such a time, we propose a stochastic Petri net method. Our stochastic Petri net method first builds a Petri net model of a hypermedia scenario. A data unit is presented as a place in a Petri net. Out going arc form a place is mapped with a "spent time distribution table". Therefore, we can perform Monte Carlo simulation to estimate the time needed to go through the Petri net from the start place to the final place. The estimated time is the time required to finish the hypermedia scenario. Once we have user's satisfaction p and time required to read t for each hypermedia scenario, then an optimal schedule is the sequence of scenarios in the order of p/t.
항정신병약물을 처음으로 사용하는 초발 정신증 환자에서 나타나는 체중 및 대사성 지표의 변화 : 후향적 연구
김우진,심주철,공보금,강제욱,문정준,김정은,김민걸,박민경,김성진,김현정,정도운 대한생물치료정신의학회 2011 생물치료정신의학 Vol.17 No.2
Objectives:This study was to identify weight & metabolic changes in first-episode psychotic patients with antipsychotics use and investigate the differences of weight & metabolic changes between first-episode psychotic patients and controls with antipsychotics use. Method:In this retrospective study, twenty eight first-episode psychotic patients and twenty eight controls with schizophrenia, schizoaffective or bipolar disorder defined by DSM-IV criteria were included. Information about demographic and clinical characteristics of the subjects was gathered from the medical records. Also body weight, sBP, dBP, fasting glucose, lipid profile and WBC count were evaluated before and after antipsychotics use. Rogistic regression was conducted to assess factors associated with weight gain. Results:First-episode psychotic patients showed more weight and BMI changes than controls after antipsychotics use, and these changes continue over 12 months. On the other hand, there were no significant factors associated with weight gain. Conclusion:The results of present study suggest that antispychotics is one of the major causes inducing weight gain of psychotic patients and antipsychotics-induced weight gain is more vulnerable to drug-naive first-episode psychotic patients.
Jeong, Gyeong Rok,Kim, Juyoung,Kang, Shin-Geol,Jeong, Jong Hwa Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.7
Two isomers of a new tetraaza macrotricycle 2,2,4,9,9,11-hexaazamethyl-1,5,8,12-tetraazatricyclo[$10.2.2^{5.8}$]-octadecane ($L^2$) containing additional N-$CH_2CH_2$-N linkages, C-meso-$L^2$ and C-racemic-$L^2$, have been prepared by the reaction of 1-bromo-2-chloroethane with C-meso-$L^1$ or C-racemic-$L^1$ ($L^1$ = 5,5,7,12,12,14-hexamethyl-1,4,8,11-tetraazacyclotetradecane). Both C-meso-$L^2$ and C-racemic-$L^2$ react with copper(II) ion to form $[Cu(C-meso-L^2)]^{2+}$ or $[Cu(C-racemic-L^2)]^{2+}$ in dehydrated ethanol, but do not with nickel(II) ion under similar conditions. Crystal structure of [Cu(C-racemic-$L^2$)($H_2O$)]$(ClO_4)_2$ shows that the complex has distorted square-pyramidal coordination geometry with an apically coordinated water molecule. Unexpectedly, the Cu-N distances [2.016(3)-2.030(3) ${\AA}$] of [Cu(C-racemic-$L^2$)($H_2O$)]$(ClO_4)_2$ are longer than those [1.992(3)-2.000(3) ${\AA}$] of [Cu(C-racemic-$L^1$)($H_2O$)]$(ClO_4)_2$. As a result, $[Cu(C-racemic-L^2)(H_2O)]^{2+}$ exhibits weaker ligand field strength than $[Cu(C-racemic-L^1)(H_2O)]^{2+}$. The copper(II) complexes readily react with CN- ion to yield the cyano-bridged dinuclear complex $[Cu_2(C-meso-L^2)_2CN]^{3+}$ or $[Cu_2(C-racemic-L^2)_2CN]^{3+}$. Spectra and chemical properties of $[Cu(C-meso-L^2)]^{2+}$ and $[Cu_2(C-meso-L^2)_2CN]^{3+}$ are not quite different from those of $[Cu(C-racemic-L^2)]^{2+}$ and $[Cu_2(C-racemic-L^2)_2CN]^{3+}$, respectively.
Jeong, Sanghwa,Won, Nayoun,Lee, Jinsik,Bang, Jiwon,Yoo, Jeongsoo,Kim, Sang Geol,Chang, Jeong Ah,Kim, Joonghyun,Kim, Sungjee Royal Society of Chemistry 2011 Chemical communications Vol.47 No.28
<P>A new multiplexed NIR <I>in vivo</I> imaging is showcased by using quantum dots and NaYF<SUB>4</SUB>:Yb<SUP>3+</SUP>,Tm<SUP>3+</SUP> nanoparticles. The ‘temporal’ multiplexing is demonstrated by alternating the excitation wavelengths and unmixing the emissions of different probes. Multiplexed cellular imaging and the cellular trafficking in animal models are shown.</P> <P>Graphic Abstract</P><P>A new multiplexed imaging scheme is demonstrated by alternating the excitation wavelength of quantum dots and NaYF<SUB>4</SUB>:Yb<SUP>3+</SUP>,Tm<SUP>3+</SUP> nanoparticles. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1cc12746b'> </P>
Development of Desk top Tug-barge Simulator and Evaluation Module
Jeong, Tae-Gwoen,Song, Chae-Uk,Chen, Chao,Lee, Shin-Geol,Lee, Jeong-Jin Korean Institute of Navigation and Port Research 2011 한국항해항만학회지 Vol.35 No.2
This paper is a part of the development on the safe navigation model of tugs and barges in Korea waters. desk-top tug-barge simulator is to train the crew of tugs and barges, especially tugs' crew. It is connected with steering and engine telegraph console and winch control console, and can describe three types of operation mode for a tug-barge working unit, towing mode, side by side and push mode. It can also record and assess each simulation run. The evaluation module can confirm the result of a finished simulation run and help trainees to find and correct their faults, and it is composed of result evaluation and process evaluation.