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Hyuk Jega,Ki Jong Kim,Hyun Ju Jun 국제물리치료학회 2014 Journal of International Academy of Physical Ther Vol.5 No.2
The aim of this research was to investigate how the effects of body supported treadmill training with visual feedback affect the gait factors of stroke patients. Thirty subjects (21 male, 9 female) with a diagnosis of stroke were taken to the hospital to participate in this study. The subjects received body supported treadmill training with visual feedback. The training was executed for 6 minutes, 3 times a day per week for 19 weeks after general exercise. The effects of the visual feedback in the body supported treadmill training were evaluated by measuring the average gait cycle and the average step length of the affected and unaffected. The collected data were statistically analyzed by using a paired t-test. The results of this study were a significant improvement of the average gait cycle and no statistically significant difference of the average step length. The gait cycle average had a statistically significant difference in gender, age, etiology, paretic side, and step length average. There was no statistically significant difference in infarction within etiology. Therefore, it was necessary to apply the easy and simple with the treadmill training in the rehabilitation of the stroke patients. This study will require a variety of outcome measures related to the effects of treadmill training with gait factors.
Quality assessment by using Rhod-2 staining in porcine matured and fertilized oocytes
Ho-Guen Jega,Hyo-Jin Park,Jin-Woo Kim,Seul-Gi Yang,Min-Ji Kim,In-Su Kim,Sang-Min Lee,Bo-You Heo,Joung Jun Park,Deog-Bon Koo 한국수정란이식학회 2018 한국수정란이식학회 학술대회 Vol.2018 No.11
Mitochondrion is an organelle for regulating calcium (Ca2+) homeostasis. Mitochondrial Ca2+ plays important roles on oocyte maturation, fertilization and embryonic development for ATP production. Low quality oocytes have mitochondrial dysfunction, which lead to overloaded Ca2+ in mitochondria. Recently, Rhod-2 is well known as a mitochondrial derived Ca2+ indicator. However, the changes of Rhod-2 in matured or fertilized porcine oocytes have not been reported. Therefore, the aim of study was to identify the effects of mitochondrial Ca2+ using Rhod-2 on quality assessment of matured oocyte and zygotes in pigs. Thus, we classified two groups (group 1: G1, compact COCs and group 2: G2, uncompact COCs) according to differences of cumulus cells amount and cytoplasm morphology in germinal vesicle (GV) stage of porcine COCs. Therefore, we investigated number of Rhod-2 spots in matured and fertilized oocytes from G1 and G2 groups. The Rhod-2 spot numbers were separated into four parts; n<10, 10≤ n < 20, 20 ≤ n < 30, and 30 < n. The Rhod-2 spots number of G2 group had greater than G1 group in part of 20 ≤ n. Additionally, we investigate mean number of Rhod-2 spots from G1 and G2 groups in matured and fertilized oocytes. As a result, we confirmed that average number of Rhod-2 spots in G2 group increased than that of G2 group. Finally, we also measured the Rhod-2 intensity in matured and fertilized oocytes of G1 and G2 groups. Interestingly, the Rhod-2 intensity in G2 group was higher than that of G1 group. (oocyte: p < 0.001 and fertilized oocyte: p < 0.05). These results demonstrated that changes in Rhod-2 spots and intensity were increased in low quality of matured and fertilized oocytes. Therefore, our results suggest that the differences in mitochondrial calcium level are associated with morphological quality of porcine COCs.
Kwang Won Seo,Gyu Rak Chon,Jong Joon Ahn,Yangjin Jega,Sang Bum Hong,Chae Man Lim,Younsuck Koh Korean Society of Critical Care Medicine 2006 Acute and Critical Care Vol.21 No.1
BACKGROUND: To evaluate effects of 5 expiratory sensitivity (ESENS) levels (5%; 15%; 25%; 35%; 45%) on lung mechanics and the effects depending on the two P(0.1) levels ( or =3 cm H2O). METHODS: Prospective, randomized, physiologic study for intubated adult patients during weaning from mechanical ventilation. Patients were randomly submitted to the 5 settings of ESENS in the Galileo ventilator (Galileo Gold, Hamilton Medical AG, Switzerland). Physiologic variables were continuously measured using a Bicore CP-100 pulmonary mechanics monitor (CP-100, Bicore, USA). RESULTS: Thirteen patients, ten men and three women, with a mean age of 65.2+/-16.1 yr were studied. Tidal volume (V(T)) decreased significantly from ESENS 5% to 45%. With increasing levels of ESENS, respiratory rates (RR) steadily increased from ESENS 5% to 35% and 45%. Shallow breath index (F/V(T)) increased significantly from ESENS 5% to 45%. Inspiratory time (T(I)) decreased gradually significantly from ESENS 5% to 45%. RR and F/V(T) increased from ESENS 5% to 15% and 45% and V(T) decreased gradually in patients with P(0.1) or =3 cm H2O. CONCLUSIONS: The proper adjustment of expiratory sensitivity (ESENS) levels improved patient-ventilator synchrony and decreased respiratory rates and shallow breath index, especially in P(0.1)
Retrospective analysis of transbronchial cryobiopsy: the first report in Korea
( Woori Jo ),( Chuiyong Pak ),( Jin Hyoung Kim ),( Soohyun Bae ),( Byung Ju Kang ),( Seung Won Ra ),( Kwang Won Seo ),( Jong Joon Ahn ),( Soyeoun Lim ),( Hee Jeong Cha ),( Taehoon Lee ),( Yangjin Jega 대한결핵 및 호흡기학회 2019 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.127 No.-
Background: Interstitial lung diseases(ILD) are heterogeneous group of lung diseases that require a multidisciplinary approach through discussion with clinicians, radiologists, and pathologists. Surgical lung biopsy is the gold standard for pathologic diagnosis of ILD. Recently, the usefulness of transbronchial cryobiopsy (TBC) has increased in the assessment of ILD. As far as we know, there is no study in Korea on the role of TBC in ILD diagnosis, yet. This study first evaluated the significance of TBC in suspected cases of ILD in Korea. Methods: The medical records of 17 patients suspected of ILD who were performed TBC at Ulsan University Hospital from August 2016 to June 2019 were retrospectively evaluated. Results: Seventeen patients with a mean age of 67 years were included in this analysis and there were 47%(eight patients) of women. The 1.9 mm sized probe was used for three patients and 2.4 mm sized probe was used for 14 patients. The median number of specimens per procedure was four (range; 1-9). The mean diameter of the specimens was 0.5 cm(range; 0.2-1.2cm). The diagnostic yield of TBC was 47.1%(eight patients). The frequent histopathologic results included usual interstitial pneumonia(two patients), organizing pneumonia(two patients) and adenocarcinoma(two patients). In the multidisciplinary diagnosis, they were diagnosed with idiopathic pulmonary fibrosis(two patients), cryptogenic organizing pneumonia(two patients) and adenocarcinoma(two patients). Four of the nine patients with non-diagnostic histopathologic patterns were able to be diagnosed after a multidisciplinary review. As a result, the number of patients who could be diagnosed by TBC increased to 12 patients(70.6%). The complication occurred in eight patients including mild bleeding (three patients) and pneumothorax(four patients). Conclusions: The diagnostic yield of TBC in this study was 47.1% and increased to 70.6% after a multidisciplinary diagnosis. The value of TBC as the alternative methods of surgical lung biopsy should be evaluated through further study.
( Hong Gil Jeon ),( Ju Hwan Park ),( Hye Min Park ),( Woon Jung Kwon ),( Hee Jeong Cha ),( Young Jik Lee ),( Chang Ryul Park ),( Yang Jin Jega ),( Jong Joon Ahn ),( Seung Won Ra ) 대한결핵 및 호흡기학회 2014 Tuberculosis and Respiratory Diseases Vol.76 No.2
We hereby report a case on bronchogenic cyst which is initially non-infected, then becomes infected after bronchoscopic ultrasound (US)-guided transesophageal fine-needle aspiration (FNA). The non-infected bronchogenic cyst appears to be filled with relatively echogenic materials on US, and the aspirate is a whitish jelly-like fluid. Upon contrast-enhanced MRI of the infected bronchogenic cyst, a T1-weighted image shows low signal intensity and a T2-weighted image shows high signal intensity, with no enhancements of the cyst contents, but enhancements of the thickened cystic wall. The patient then undergo video-assisted thoracic surgery 14 days after the FNA. The cystic mass is known to be completely removed, and the aspirate is yellowish and purulent. To understand the image findings that pertain to the gross appearance of the cyst contents will help to diagnose bronchogenic cysts in the future.