The diagnosis of coronoid impingement using computed tomography

Baik, Jee-Seon,Huh, Kyung-Hoe,Park, Kwan-Soo,Park, Moo-Soon,Heo, Min-Suk,Lee, Sam-Sun,,Choi, Soon-Chul 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

Coronoid impingement can cause limitation of mouth opening. In many cases, it appears to be related to the coronoid hyperplasia. We present a case of mouth opening limitation caused by coronoid impingement on the posterior surface of the zygomatic bone without coronoid hyperplasia. The bony changes in coronoid and zygoma including surface irregularity and discontinuity of the cortex and sclerotic change of inner medullary space were noted on computed tomography (CT) scans in different level of axial planes. Through another CT scans in open mouth position could demonstrate that those bony changes were caused by the contact of both surfaces against each other. In case coronoid impingement is suspected of the many possible causes, the open mouth CT scans will be needed to reveal the direct impingement of coronoid on zygoma even without coronoid hyperplasia.

일차보건의료 관점의 보건의료 시스템 모니터링하기: 사람 중심의 통합된 의료 서비스 전달을 위하여

김지애,박춘선 건강보험심사평가원 2023 HIRA RESEARCH Vol.3 No.1

100m 달리기시 최고 속도 구간과 감속 구간의 동작 비교 연구

은선덕,정철수,배성제 한국운동역학회 1996 한국운동역학회지 Vol.6 No.1

본 연구의 목적은 100m 달리기에서 최고 속도 구간과 감속 구간에서의 동작을 비교하여 감속의 원인을 규명하는 데 있다. 두 구간에 대한 주요 운동학적 변인인 신체 중심의 속도와 변위, 보속과 보폭, 상체의 전경각, 관절각, 각속도를 분석하여 다음과 같은 결론은 얻었다. 감속 구간에서의 지면 접촉 기간 동안과 체공 기간 동안의 신체 중심의 수평 속도는 최고 속도 구간에 비해 느린 것으로 나타났다. 보속은 최고 속도 구간에 비해 느린 것으로 나타났고, 지지 시간은 긴 것으로 나타났으며, 체공 시간은 차이가 나타나지 않았다. 보폭은 최고 속도 구간에 비해 짧은 것으로 나타났고, 착지시 신체 중심과 발끝의 수평 거리는 최고 속도 구간에 비해 긴 것으로 나타났다. 또한 상체의 전경각은 착지시에만 차이가 있었으며 최고 속도 구간에 비해 작고, 무릎 관절각은 착지시와 이지시에 있어서 최고 속도 구간에 비해 작았다. 그리고 고관절각은 반대발의 이지시와 착지시, 그리고 최소값에 있어서 최고 속도 구간에 비해 크고, 운동 범위에 있어서는 작은 것으로 나타났다. 또한 무릎 관절 각속도는 최고 속도 구간과의 비교에서 차이가 나타나지 않았다. The study was conducted to make a comparative analysis of running motion and to examine the difference in the deceleration phase(80∼90m) and the Max-speed phase(30∼40m) during the 100-meter Sprint. In this study, data was analyzed with variables including velocity and displacement of center of gravity, stride frequency, stride length, foward angle of upper body, joint angle, angular velocity in the deceleration phase and the max-speed phase. The conclusions of the study were as follows ; 1. Horizontal velocity of the center of gravity in the deceleration phase was found to be slower than that in the max-speed phase in the supporting period and non-supporting period. 2. Stride frequency in the deceleration phase was found to be slower than that in the max-speed phase, and supporting time n the deceleration phase was longer than that in the max-speed phase, also there was no difference between each phase in nonsupporting time. 3. Stride length in the deceleration phase was to be found shorter than that in the max-speed phase. 4. Horizontal distance between the center of gravity and toe in the deceleration phase was to be found longer than that in the max-speed phase. 5. Forward angle of upper body at the moment of touch down in the deceleration phase was found to be smaller than that in the max-speed phase. 6. Knee angle at the moment of touch down and take off in the deceleration phase were found to be smaller than in the max-speed phase. 7. Hip angle at the moment of touch down and take off of the other foot, and minimum hip angle in the deceleration phase were found to be larger than that in the max-speed phase, and range of, motion in the deceleration phase was smaller than that in the max-speed phase. 8. Knee angular velocity at the moment of touch down of the other foot toward flection in the deceleration phase was found to be larger than that in the max-speed phase.

異功散이 마우스 黑色腫의 肺轉移 抑制에 미치는 抗癌 및 免疫作用에 關한 硏究

李膳求,河智容 대한동의병리학회 1997 동의생리병리학회지 Vol.11 No.1

종양은 그 발생원인과 성장기전이 자세히 밝혀져 있지 않는 질병으로 최근 성인사망의 제 1원인으로 급격히 발생빈도가 증가하고 있다. 종양환자의 수는 점점 증가하는 추세이며, 그에 따른 사망자의 수도 늘고 있다. 종양을 치료하는 방법으로 수술요법·방사선요법·화학약물요법·골수이식·면역요법·호르몬요법 등이 사용되어 왔으나 최근에 천연물 특히 전통적인 한약재를 이용한 종양파괴 및 종양에 있어 성장을 억제하는 약재의 연구가 시도되어 왔다. 한의학의 특정 약재 및 처방의 항암효과가 경험적으로 알려져 왔으며, 과학적이고 객관적인 병태를 통하여 이러한 약재의 효능을 검증하려는 실험이 최근에 시도되고 있다. 이에 본 연구는 補眞氣虛弱 및 治 久嗽不己 脾胃虛弱 등의 효능이 있는 異功散을 이용하여 B16세포의 전이억제능, 흑색종의 증식억제 및 면역능에 대하여 연구하고자 하였다. 본 연구에서는 시험관내 세포독성능을 알아보기 위하여 MTT법으로 각 농도별로 처리된 이공산을 B16세포에 적정농도로 처리하여 생존율 및 IC50을 측정하였다. 또한 생쥐를 이용한 동물실험으로써 흑색종을 폐에 전이시켜 이공산 투여후 흑색종의 집략수를 측정하였다. 동시에 항암효과와 면역능과의 관련성을 알아보기 위하여, Interleukin-2생산능과 NK-Activity를 측정하였다. 이공산의 생쥐에 대한 폐전이 흑색종의 억제효능과 면역반응에 미치는 영향을 알아보기 위한 실험에서 시험관내 세포독성 측정에서는 2㎍/well의 농도로부터 2배 희석시켜 MTT법으로 측정한 결과 유의성있는 억제를 보였으며 2,2124㎍/well의 IC50을 얻었다. 흑색종의 억제능을 측정한 결과 7일과 14일째에 유의성있는 억제를 보였고, 21일째는 흑색종이 폐의 전면에 분포되어 측정되지 않았다. 이 공산 투여후 생쥐의 IL-2의 생산능을 측정한 결과 이공산 투여군에 있어 투여 7일, 14일, 21일째에 모두 유의성있는 증가를 보였다. 그리고 NK-Activity를 측정한 결과 이공산 투여군이 대조군과 비교하여 유의한 차이는 보이지 못하였다. 이상의 결과를 종합하여 볼 때 이공산이 B16세포에 대하여 직접 세포독성능을 나타내며 보조 T 세포를 자극하여 IL-2의 생산능을 증가시켜 흑색종의 전이 및 증식을 억제하는 것으로 추정된다. 따라서 전이억제의 기전과 면역반응에 관련된 연구가 더욱 진행되어야 할것으로 사료된다. Herbal medicine as a candidate for effective cancer treatment recently gain positive concerns in field of therapeutic oncology. that is why some oriental medicine has been empirically safer in toxicity than anticancer drugs used in western medicine, and to show excellent therapeutic efficacy in human trial. Thus, these effects by clinically applied-herbs have not yet fully demonstrated in experimental tumor model. This study was initiated to evaluate antitumor effect of Ikongsan as candidate of antitumor-hebal agent against B16 melanoma metastasized into murine lung, and to examine association between immune parameter an anti-metastasis effect by Ikongsan. In experiment to test whether Ikongsan can directly kill cancer cells in vitro or not, Ikongsan showed direct killng action in concentration or higher against B16 melanoma cells using MTT assay. And also, in another experiment to know whether Ikongsan can inhibit growth and metastasis of cancer cell or not, Ikongsan significantly inhibited lung metastasis induced by intravenous injected-melanoma in inbred C57BL/6 mouse. When we quatiated interleukin-2 production, we could obtain results that in Ikongsan-treated group(7th, 14th, 21th), IL-2 production was significantly increased, But, NK activity in Ikongsan-treated group was not in significantly difference as compared to that of Ikongsan-nontreated group. These results show that Ikongsan can inhibit growth of B16 melanoma cells through biological mechanisms.

柴胡桂枝湯이 CCl₄로 誘發된 白鼠의 肝損傷에 미치는 影響

河智容,朴慶寔,李善熙 대한동의병리학회 1996 동의생리병리학회지 Vol.10 No.2

肝은 人體內의 血量을 調節하고 각종 大事, 分泌, 合成에 관여하는 중요한 기관이며, 病理的으로는 대사물질에 의한 중독에 민감하게 반응하여 간세포의 변성, 괴사, 지방축적, 간효소의 누출 등을 일으킨다. 간에 손상을 줄 수 잇는 요인 은 많으며, 최근에는 중독에 의한 손상이 증가하고 있다. 시호계지탕은 상한론에 ‘傷寒六七日 發熱徵惡寒 肢節煩疼 徵嘔 心下支結 外證未去者 柴胡桂枝湯主之에 사용된 처방으로 임상적으로 간손상에 사용되었으나, 실험적 연구는 실시되지 않앗다. 따라서 본 연구에서는 Sprague-Dawely 흰쥐에 사염화탄소로 중독성 간손상을 일으킨 후 시호계지탕을 투여하여 간손상에 미치는 영향을 알아보았다. Sprague-Dawely 흰쥐에 CCI₄와 Olive oil을 1:4로 혼합하여 4주간 격일로 경구투여하여 간손상을 유발하였다. 그 후 시호계지탕을 10㎎/㎏(B.W)로 하여 매일 경구투여 하였다. 실험 첫주부터 매주 각 군의 평균몸무게와 평균 사료섭취량을 측정하였고, 실험 마지막날 채혈한 뒤 순수혈청에서 AST, ALT, TP, Albumin, Gloulin, ALP, LDP를 검사 하였다. AST는 CCI₄處理群에 비하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 減少하였으며, CCI₄處理後柴胡桂枝湯投與群 B의 境遇는 有意性이 認定되었다. (P〈0.05). ALT는 CCI₄處理群에 비하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 유의성있는 감소를 보였다. (P〈0.05). CCI₄處理群과 比較하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B는 Tota protein의 경우 큰 차이가 없었으며, Albumin은 감소하였고, Globulin은 增加하였으나 有意性은 없었다. Albumin과 Globulin의 比率은 減少하였으나, 有意性은 없었다. ALP는 CCI₄處理群에 比하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 有意性있는 減少를 보였다.(P〈0.05). LDH는 특별한 傾向을 찾을 수 없었다. 肝의 重量을 測定한 結果 CCI₄處理後群에 比하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B 모두 有意性 있는 減少를 보였다. (P〈0,05). 體重과 飼科 攝取量의 變化는 CCI₄處理群에 比하여 CCI₄處理後柴胡桂枝湯投與群 A와 CCI₄處理後柴胡桂枝湯投與群 B이 增加하였으나 유의성은 없었다. 以上으로 보아 柴胡桂枝湯이 CCI₄로 誘發된 肝損傷의 境遇에 AST, ALT, ALP, 肝의 重量變化에서 有意性있는 減少(P〈0.05)를 보였으며, 體重과 飼科 攝取量의 增加로 보아 肝損傷 回復에 대한 治療效果가 있을 것으로 思料된다. This study was carried out to investigate the effects of Sihogyejitang extract on the recovery of liver in CCI₄-intoxicated rats. In this study, SD-Rats were divided into 4 experimental groups; Control(Placebo, 0.85% NaCl), Experi-mental (CCI₄-intoxicated+Placebo, 0.85% NaCl), Siho A(Treated with Sihogyejitang extract (10㎎/㎏) after CCI₄intoxication), Siho B(Treated with Sihogyejitang extract (50㎎/㎏) after CCI₄-intoxication), Biochemical assays for serum enzyme activities such as AST, ALT, TOtal protein, Albumin, Globulin, ALP, LDH, and Biological assay for Liver weight, Body weight, Food, intake were performed. The results obtained were summarized as follows: 1. Siho A group showed lower serum AST activity than CCI₄-intoxicated group significantly, and Siho B group showed lower than Control group(P〈0.05). 2. Both siho A group and siho B group showed lower serum ALT activity than CCI₄-intoxicated group significantly. 3. As to Total protein, Siho A group and Siho B group were classed with CCI₄-intoxicated group. As to Albumin, Siho A group and siho B group were decreased than CCI₄-intoxicated gruop, but not significant. As to Globulin, siho A group and B group were increased than CCI₄-intoxicated group, but not significant. As to Globulin, ratio siho A group and Siho B group were decreased than CCI₄-intoxicated group, but not significant. 4. As to ALP, Siho A group and Siho B group were decreased than CCI₄-intoxicated group significantly(P〈0,05). 5. As to serum LDH, There were no trend in all groups. 6. As to liver weight, Siho A group and Siho B group were decreased than CCI₄-intoxicated group significantly. 7. As to Body weight and Food intake, Siho A group and Siho B group were increased than CCI₄-intoxicated group, buy not significantly.

乾癬患者 臨床報告

吳恩英,朴惠宣,池鮮渶,具德謨 동의대학교 한의학연구소 2001 동의ㆍ경산 한의학 학술대회 Vol.5 No.-

A Reports were done on proriasis which were treated by medications of Sasang Constitution and Constitution-Acupunture in Dept. surgery, opthalmology &tolaryngology, college of Oriental Medicine, Kyungsan University, Pohang, Korea, from May 30. 2000 to JUN 30 2001. we gave score and checked involvement, plaque, erythematous popules, invasiveness according to psoriasis area and severity index. The results were as follows: 1. Sasang Constitution classification was Soyanggin 14(93.33%), Taeumgin 1(6.67%) in the 15 cases. Hyungbangsabaeksan is used in 9 cases(60%), Yanggeuksanhoatang is used in 3 cases(13.11%), Geopungchunggisan is used in 3 cases(20%), Hyungbangdojucksan is used in 1 case(6.57%). 2. In the 9 cases, we checked for over 4 weeks, clinical severity of involvement, plaque, total score(psoriasis area and severity index) was siginificantly decreased(p<05). clinical severity of erythematous popules, itching was decreased but lt is not siginificant(p>05). 3. The mean duration of treatmemt was 73.3 days, result of Excellent or Good improvement was showed on over 120 days. These resilts indicate that Sasang Constitution and Constitution-Acupuntuer treatment is effetive on psoriasis and the more study is needed.

한국어판 모호한 의도-적개심 설문지 개발

장형윤,이선구,김경란,이수영,박진영,김은주,강지인,이은,안석균 大韓神經精神醫學會 2009 신경정신의학 Vol.48 No.1

Objectives We studied the psychometric properties of a Korean version of the Ambiguous Intentions Hostility Questionnaire (K-AIHQ), which measures hostile social-cognitive biases for use in the research on paranoia. Methods The translation and back-translation of the AIHQ with concern for the cultural differences were done according to the standard procedure. A sample of 83 healthy volunteers completed the K-AIHQ. Results The scores of the K-AIHQ were comparable to the results of the original studies. The Paranoia Scale was correlated with the K-AIHQ, but Magical Ideation and Perceptual Aberration scales were not correlated with the K-AIHQ. The interrater reliabilities of the items in each situation were in the acceptable range. Conclusion The KAIHQ seems to be a reliable and valid test to measure the hostile social Cognitive biases of patients with paranoia.

처의 성적 자기결정권 보호 : 부부강간죄의 성립여부에 관한 고찰

장영민,손지선 梨花女子大學校 法學硏究所 2001 法學論集 Vol.6 No.1

The problem of marital rape is one of the contral issues of protection of woman's right by the criminal law. There are no explicit provisions in the korean criminal law against marital rape. On this reason, it is needed to deploy the means of protecting married woman's sexual autonomy. The purpose of establishing the regulation against marital rape is protection of woman's sexual automy and sexual autonomy should be conceived of as one of the basic human rights and the rights of pursuing happiness. It took a long time for us to recognize wife's right of sexual automony and to reach a consensus to accuse the husband of rape when wife's right is iufringed by him. The reason why it took so long a time is as follows. The first is the patriarchally distorted way of thinking about marriage and sexuality. Second is that common consciousness of law has been effected in conceiving vilolent sexual intercourse in conjugal relation as cirme because, it was thought, marriage premises the sexual relations. The concept of 'charateristics of conjugal relations', that is suggested as the basis for not recognizing marital rape as a crime, is so changeable and unclear according to the time and culture. Today sexuality means not keeping one's sexuality passively from any intrusion, but freely dertermining it positively. Because it is the same as to a married woman, husband doesn't have a right to demand a violent sexual intercourse with his wife. The criminal law and the related laws regulating sexual and domestic violence provide a procedure of dealing the criminals in the Family Court, not in the Criminal Court, By that procedure it is possible to take special measure towards crimianals on the consideration of the special characteristics of crimes occurred in domestic relationships.

코로나19 대응을 위해 한시적으로 허용된 전화상담·처방에 대한 병원급 의료공급자 인식과 만족도에 관한 연구

유혜림,김수민,박춘선,김지애 건강보험심사평가원 2021 HIRA RESEARCH Vol.1 No.1

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Paraquat 처리에 의한 Bacillus megaterium의 Superoxide dismutase 활성저해

최경호,김춘숙,유지선 대구효성가톨릭대학교 1993 연구논문집 Vol.46 No.1

The effect of paraquat (1, 1'-dimethyl-4,4'-dipyridilium dichloride) treatment on activity of microbial superoxide dismutase(SOD), a key enzyme which protects the organism from toxicity of oxygen, was investigated. Exponentially growing cells of Bαcillus megaterium(ATCC 1987) were treated with 1.OmM paraquat by cultivation in the concomitant presence of the paraquat. Paraquat-treated culture showed a linear decrease in turbidity, cellular weight and vidable cell counts while those of control culture showed a linear increase until nine hours of cultivation. After nine hours of cultivation, turbidity(0.68), dry cell weight(1.19mg/ml) and viable cell counts(5.0×19?cells/ml) of the treated culture reached to approximately 62%, 83% and 4% of those of initial, respectively. Paraquat-treated culture(in vivo) showed a SOD activity of 0.68unit/ml and a specific activity of 1.79unit/mg protein after nine hours of cultivation. These values were equel to 22% and 44% of the control culture, respectively. When enzymes were liberated from sonic-disruptured cells(in vitro) by orderly using of sodium phosphate buffer, buffered lysoyme and triton X-100, paraguat-treated culture showed an increased activity of the engyme, while control culture did not show any significant increase of the enzyme activity. Activities of SOD drastically decreased as increasing the paraquat concentration in the crude enzyme lysate, although protein content was not significantly varied. The lysate dissolved 1.0mM paraquat showed a specific activity of SOD decreased to 45% of control lysate. It was noticed that the decreasing rate was approximately similar to that of the lysate prepared from paraquat-treated cells.