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개에서 회장내 단백이 췌효소 및 담즙분비와 위배출 및 소장주행 시간에 미치는 영향
강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),박인서(In Suh Park),정재복(Jae Bock Chung),이상인(Sang In Lee),송시영(Si Young Song),정준표(Jun Pyo Chung),(Hiroshi Tohno),(eugene P . DiMagno) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.6
N/A The aim of this study is to determine if protein in the ileum of dogs affects postprandial pancreaticobiliary secretion, gastric emptying, small bowel transit time, and circulating levels of gastrointestinal regulatory peptides such as peptide YY (PYY), neurotensin (NT), and pancreatic polypeptide (PP). Five dogs were prepared with permanent infusion and aspiration catheters in the duodenum and ileum. Ileal infusion (2 ml/rnin) was begun coincidentally with feeding a 300 Cal mixed nutrient meal containing both a iiquid marker (PEG 4000) and a solid marker (99mTc-sulfur colloid) in a conscious state of dogs. Ileal infusates were isosmolar solutions containing either 0.9% NaCl (control study) or 20 mg/rnl of protein solution (protein infusion study) in the 3:1 ratio of casein to essential amino acids. The secretory pattern of amylase and lipase was parallel, but. the secretion of trypsin was non-parallel to secretion of amylase and lipase. The pattern of exocrine pancreatic enzyme secretion was similar both in control and intraileal protein infusion studies. The secretion of exocrine pancreatic enzymes including amylase, lipase and trypsin, were increased by intraileal protein infusion compared with their secretion in control studies, and the secretion of amylase was significantly decreased (p<0.02) by intraileal protein infusion compared with their results in control studies. Although gastric emptying of both liquid and solid meals was delayed by the intraileal infusion compared with the control studies, there was no significant delay in gastric emptying (Tl/ 2) of liquid, whereas significant difference was noticed in gastric emptying (Tl/4) ol solid (p<0.02) between the control and intraileal protein infusion studies. The small bowel transit time was significantly prolonged (p<0.01) by intraileal protein infusion compared with time measured in control studies. The mean serum levels of PYY and NT were increased by intraileal protein infusion compared with those of control studies, but the mean serum level of PP was not changed. ln conclusion, it is suggested that intraileal protein riiay promote digestion and absorption of nutrients by increasing the enzyme secretion of the pancreas, delaying gastric emptying and prolonging small bowel transit time which may be influenced by hormones such as PYY and NT.
Balakrishnan, A.,Panigrahi, B.B.,Sanosh, K.P.,Chu, Min-Cheol,Kim, T.N.,Cho, Seong-Jai Elsevier 2009 Journal of materials processing technology Vol. No.
<P><B>Abstract</B></P><P>This work attempts to improve the mechanical properties of alumina-10wt% zirconia (3mol% yttria stabilized) composite by infiltrating a glass (magnesium aluminum silicate glass) of lower thermal expansion on the surface at high temperature. The glass improved the strength of the composite at room temperature as well as at higher temperatures. There was a significant improvement in the Weibull modulus after the glass infiltration. Glass-infiltrated samples showed better thermal shock resistance. The magnitude of strength increment was found to be in the order of the surface residual stress generated by thermo-elastic properties mismatch between the composite and the infiltrated glass.</P>
박재학(Jai Hak Park),G.P. Nikishkov 대한기계학회 2011 大韓機械學會論文集A Vol.35 No.9
SGBEM-FEM 교호법은 유한 물체 내에 존재하는 삼차원 균열을 해석하는 유용한 방법으로 알려져 있다. 이 방법으로 일반적인 평면 혹은 비평면 삼차원 균열에 대한 정확한 응력강도계수를 구할 수 있다. 기존의 방법에서는 균열을 모델화 하는데 8 절점 사각형 경계요소를 사용한다. 그러나 임의 형상의 균열의 경우는 3 절점 삼각형 요소를 사용하여 균열을 모델화 하는 것이 더 편리하다. 따라서 본 논문에서는 3 절점 삼각형 요소와 7 절점 사각형 요소를 사용하여 전진 프런트 법으로 균열을 모델링 하였다. 사용된 균열 모델의 정확성을 검토하기 위하여 몇 가지 형상의 균열에 대하여 응력강도계수를 구하여 기존의 해와 비교하였다. The SGBEM-FEM alternating method has been known to be a very effective method for analyzing threedimensional cracks in a finite body. The accurate values of the stress intensity factor can be obtained for a general planar or nonplanar three-dimensional crack. In the existing method, eight-noded quadrilateral boundary elements are used to model a crack. In some cases, three-node triangle boundary elements are more convenient for the modeling of a crack with a general shape. In this study, a crack is modeled with three-noded triangular and seven-noded quadrilateral elements by using the advancing-front mesh generation method. The stress intensity factors are obtained for cracks with several shapes and the accuracy of results is examined.
Synthesis of nano hydroxyapatite powder that simulate teeth particle morphology and composition
K.P. Sanosh,Min-Cheol Chu,A. Balakrishnan,Yong-Jin Lee,T.N. Kim,Seong-Jai Cho 한국물리학회 2009 Current Applied Physics Vol.9 No.6
A simple sol–gel precipitation technique to synthesize nano hydroxyapatite (HA) particles (~30 nm) that show similar morphology, size and crystallinity to HA crystals of human teeth is reported. Calcium nitrate tetrahydrate and potassium dihydrogenphosphate were used as calcium and phosphorus precursors, respectively. Double distilled water was used as a diluting media for HA sol preparation and ammonia was used to adjust the pH to 11. After aging, the HA gel was dried at 40 ℃ and calcined to different temperatures ranging from 200 to 600 ℃. The dried and calcined powders were characterized for phase composition using X-ray diffractrometry, and Fourier transform infra-red spectroscopy. The particle size and morphology was studied using Transmission electron microscopy. The particle size distribution analysis of HA powders showed skewed distribution plot. The phase and particle characterization studied above showed that HA calcined at 600 ℃ simulate HA crystals of teeth. A simple sol–gel precipitation technique to synthesize nano hydroxyapatite (HA) particles (~30 nm) that show similar morphology, size and crystallinity to HA crystals of human teeth is reported. Calcium nitrate tetrahydrate and potassium dihydrogenphosphate were used as calcium and phosphorus precursors, respectively. Double distilled water was used as a diluting media for HA sol preparation and ammonia was used to adjust the pH to 11. After aging, the HA gel was dried at 40 ℃ and calcined to different temperatures ranging from 200 to 600 ℃. The dried and calcined powders were characterized for phase composition using X-ray diffractrometry, and Fourier transform infra-red spectroscopy. The particle size and morphology was studied using Transmission electron microscopy. The particle size distribution analysis of HA powders showed skewed distribution plot. The phase and particle characterization studied above showed that HA calcined at 600 ℃ simulate HA crystals of teeth.
Sol-gel synthesis of pure nano sized β-tricalcium phosphate crystalline powders
K.P. Sanosh,Min-Cheol Chu,A. Balakrishnan,T.N. Kim,Seong-Jai Cho 한국물리학회 2010 Current Applied Physics Vol.10 No.1
β-Tricalcium phosphate (β-TCP) nano powders (~80 nm) were synthesized using a simple sol.gel route with calcium nitrate and potassium dihydrogenphosphate as calcium and phosphorus precursors, respectively. Double distilled water was used as a diluting media for β-TCP sol preparation and ammonia was used to adjust the pH. After aging, the β-TCP gel was dried at 40 ℃ and calcined to different temperatures ranging from 200 to 800 ℃. The dried and calcined powders were characterized for phase composition using X-ray diffractrometry (XRD) and Fourier transform-infrared spectroscopy (FT-IR). The particle size and morphology was studied using Transmission electron microscopy (TEM). Calcination revealed that with increase in temperature, both the crystallinity and crystallite size of β-TCP particles increased. Particle size distribution analysis of the calcined β-TCP at 800 ℃ showed a narrow skewed distribution plot centered between 70 and 80 nm. This value was in closed agreement with particle size values obtained from XRD analysis (83 ± 6 nm). The present study showed that narrowly distributed, high crystalline,pure β-TCP could be obtained using this simple technique for biomedical applications.