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Yong‑Moon Lee,Man Hwan Oh,Jai‑Hyang Go,Kyudong Han,Song‑Yi Choi 한국유전학회 2020 Genes & Genomics Vol.42 No.12
Background: Triple-negative breast cancer (TNBC) is a heterogeneous entity that encompasses several subtypes with distinct molecular characteristics. The patients with TNBCs show unpredictable response to the chemotherapy, and further there is the lack of effective agents. Thus, many studies have been underway to discover targeted therapy suitable for patients with specific genetic alterations in each molecular subtypes. TNBCs are classified as four major molecular subtypes according to the gene expression patterns. These are luminal androgen receptor (LAR), mesenchymal-like, immunomodulatory (IM), and basal-like types. Conclusion: Here, we discuss the unique molecular features of each subtype as well as promising targets for anti-cancer therapy.
강진경(Jin Kyung Kang),최흥재(Heung Jai Choi),김경희(Kyung Hee Kim),황용(Yong Hwang),김용범(Yong Bum Kim),이원영(Won Yung Lee) 대한소화기학회 1985 대한소화기학회지 Vol.17 No.2
N/A Most authorities agree the higher incidence of gallstones among diabetic patient. Although many reports on gallstones or diabetes mellitus have been published, and actual correlation between gallstones and diabetes mellitus remains obscure. The purpose of this reports is to know the incidence of gallstone in diabetics and of diabetics in the patients with gallstone. Authors studied prospectively and clinically the diabetics in a group of 173 patients with gallstones and gallstone in a group of 98 diabetic patients who were admitted to Yonsei University Yong-Dong Hospital for the same period of April 1983 to May 1984. The results obtained are summarized as follow: The incidence of gallstone to general admission patients is 1.5% and the prevalence of diabetes mellitus to total in-patients is 0.8% The gallstone was found in 11.0% of diabetics and were diabetic 19.4% of patients with gallstones. The age of peak incidence of gallstones is 5th decade and female was more prevalent than male with the ratio of 1.37:1. The age of peak incidence of diabetes mellitus is 6 th decade and female is less prevalent with the ratio of 0.72:l.3, The most common characteristic finding of patients of gallstones with diabetes mellitus is symptomless(42.1%)4, There is no significant difference in serum levels of cholesterol and triglyceride between diabetic and non-diabetic groups or with and without gallstones. 5. Comparative study on location of stones revealed, 72.8% in gallbladder only, 12.7% in common bile duct only, 4. 6% in intrahepatic duct only, and remainders in multiple site. There is no significant difference in terms of location of stone between diabetic and nondiabetic group.
전자 서베잉을 이용한 서베이드 금관과 국소의치 프레임워크 디자인
홍용신,박은진,김성균,곽재영,허성주,박지만 大韓齒科保存學會 2011 Restorative Dentistry & Endodontics Vol.36 No.6
구강 스캐너와 CAD/CAM 기술로 인해 컴퓨터로 제작하는 방식이 활발히 보급된 고정식 보철 증례와는 달리, 의치를 디지털 방식으로 제작하는 데에는 아직 한계가 많다. 촉각을 느낄 수 있는 입력 장비와 전자 서베잉의 개념, 그리고 쾌속 조형법의 적용으로 인해 국소의치를 디지털로 제작할 수 있는 솔루션이 최근 소개되고 있다. 본 증례보고에서는 이러한 국소의치의 디지털 솔루션을 이용하여 총 다섯 명의 환자에서 서베이드 금관 및 국소의치를 제작하였다. 인상 과정상의 문제로 모형과 실제 치아 사이의 형태적 차이가 있었던 경우를 제외하고는 국소의치의 적합도는 우수했으며, 장착 후 안정성과 착탈 시의 유지력 또한 임상에서 적용하는 데에 문제가 없었다. There are still many limitations on fabricating dentures using digital method while computerized production of fixed prostheses utilizing intraoral scanner and CAD/CAM technology has propagated rapidly. Recently the digital solution of fabricating removable partial denture by applying haptic input device, electronic surveying, and rapid prototyping was introduced. In this case presentation, five patients were treated with surveyed crown and removable partial dentures by this digital solution. Fit of dentures was excellent except for one case which showed morphological difference between the actual teeth and that of master cast by the erroneous impression process. There also was not any problem of stability and retention after adaptation in the clinical setting.
宋在偶,李鎔桓,崔仁鎬 弘益大學校 科學技術硏究所 1997 科學技術硏究論文集 Vol.8 No.-
Laboratory flume experiments to investigate the characteristics of the flows and local scour around circular shapes of bridge pier in a curved channel are performed. This study examines the effect of a circular collar devices for controlling the depth of scour. The scour depth due to a collar is about 40% of the scour depth without collar in a straight course of the flume while it is about 44% of the scour depth without collar at the location of 150˚in a curved channel. when the collar is placed yd/h=-0.2 for which the diameter of a collar is twice of the pier diameter, reduction o scour depth is very effective in a straight channel but when the collar is placed at yd/h=-0.1, the reduction of scour depth is very effective in a curved channel.
γ-ray 조사에 의한 제주산 양파의 발아 및 성분변화에 미치는 영향
박용봉,김재하,김기택 제주대학교 방사능이용연구소 2001 연구보고 Vol.15 No.-
제주지방에서 양파 저장에 관한 γ-ray 처리와 저장장소에 대한 실험을 하였다. 발아율은 저온저장, 상온저장, 동굴저장에 관계없이 무처리 양파는 약 5개월째부터 발아와 발근이 시작되었고 시간이 지날수록 증가하였으나 8월상순경에는 0Krad에서 동굴에 저장한 것은 50%, 상온에 저장한 것은 20%의 발아율을 나타내었다. 그러나 3Krad, 6Krad 처리한 것은 6개월까지는 거의 발아하지 않았다. 중량 감소는 발아와 밀접한 관계가 있는데 발아가 시작하기 전 40일 까지는 모든 처리에서 차이가 없었지만 발아가 시작되면서부터 급격히 감소하였다. 저온저장한 것은 부패율이 약 5~10%내외로 7개월후에도 식용이 가능하였으나 상온에 저장한 것은 0Krad에서 50% 정도 부패한 반면 3 Krad 및 6 Krad를 조사한 것은 저온저장인 경우 5%, 동굴저장인 경우 30 - 35%, 상온에 저장한 것은 30% 정도의 부패율을 나타내었다. 방사선조사의 다당류 변화에 대한 연구는 비교적 많이 이루어졌는데 동굴저장과 상온저장에서는 저장초기에는 3Krad 및 6Krad 조사한 것이 0 Krad보다 다소 증가 했으나 후기로 갈수록 역시 처리한 것이 양은 적으나 0Krad보다는 증가한 사실을 알 수 있었다. Allium속 채소류에 많이 들어있는데 유황은 저장장소에 관계없이 0Krad에서는 저장후반기로 갈수록 적어졌고 냉장저장한 것은 3 Krad 및 6Krad의 선량간에는 다소 차이가 있었으나 저장초기에는 유황함량이 증가하다가 12월 말경 부터는 점차 감소하는 경향을 보였다. For storage extension of Cheju grown onions, γ-ray irradiations with doses of 0Krad, 3Krad, and 6Krad were applied to onionbulbs produced in Cheju Island and their quality were compared during storage at natural cavern, low temperature (2℃), and ambient temperature. Sprouting began approximately from five months storage regardless of storage types which increased as storage extended. From early August, sprouting occured in natural cavern storage as high as 50%, in ambient temperature it was 20% in 0Krad, whereas onions with 3Krad and 6Krad γ-ray dose did not show sprouting until six months. No significant weight loss were observed in all the treatments until sprouting occured after 40 days of storage. The loss, however remarkably increased after 40 days of storage indicating that weight loss is closely correlated with percent sprouting during storage. Low temperature stored onions which showed 5-10% of rotting rates were still edible. Rotting rates reached to as high as 50% for unirradiated ambient temperature stored onions after seven months while they were 5%, 33%, and 30% in low temperature, natural cavern, and ambient temperature respectively in irradiated groups. Sugar contents were slightly increased in later period in irradiated onions under ambient temperature storage although sugar contents which included in Allium vegetables generally decreased in later storage of unirradiated onions. Sulfur contents slightly increased in early storage in irradiated onions while showed gradual decrease although the differences were not significant.
습동면유 겸용 수용성 금속가공유제의 제조 및 특성 연구
윤을용,노정석,김해원,김선덕,진경록,김재권 한국공업화학회 2004 응용화학 Vol.8 No.2
At processing of a metal process, much problems are happening by mixing between slide-way fluid and water-solubility metal-working fluid(MWF). In this study, measure physical & chemical properties and biodegradable properties of base stock and additives that is used to lubricant, and developed water-soluble metal working fluid by slide-way fluid combined use. Biodegradability of developed combined use fluid for 28 days is displayed lower than 10 ppm, and more superior performance than similar fluids in lubrication special quality test.
李載英 成均館大學校 1980 論文集 Vol.28 No.-
To develop and introduce new type of instant food of animail orgin, a model was established. Procuct sample was manufactured using egg yolk powder and non fat dry milk as major raw materials. Samples were tested in solubility, packing, preservation, palatability and composition.
백재욱,윤용운 중앙대학교 통계연구소 1995 統計論文集 Vol.- No.2
컴퓨터의 발달은 많은 것을 변화시켰는데 통계학도 예외는 아니다. 기존의 수학위주에서 컴퓨터 위주로 분석형태가 변하면서 자료의 정규성이라든지 또는 독립성의 가정이 없어도 자연현상을 이제는 있는 그대로 연구할 수 있으며, 나아가 기존의 어려운 통계학 개념을 보다 쉽게 이해할 수 있게 되었다. 본 논문에서는 여러가지 예를 이용하여 요즘 컴퓨터를 가장 많이 이용하는 방법중의 하나인 Bootstrap 방법에 대하여 알아보고자 한다. Modern statistical practice has been revolutionalized by the computer. The paradigm shift from mathematics to powerful computing has brough two benefits. The first benefit is that we can approximate the decidedly rude behavior of Mother Nature more closely than before since the new approaches do not require such polite behavior from her. The second is that the elimiation of mathematical superstructure often illuminates the statistical concepts. In this article, we review basic bootstrap methods, emphasizing, applications through illustrations with some data.