高年者의 體力에 關한 硏究

金宰圭 단국대학교 대학원 1982 學術論叢 Vol.6 No.-

The purpose of this thesis depends on offering the necessary basic data for the physical application practice required to those who are in their old ages. At the same time the weakened bodily parts are found by taking a measurement of the physical examination of the aged, and the maintenance and reservation of physical strength of the aged are grasped in this thesis. Therefore 90 old persons who relatively interested themselves in health and whose maintenance state of bodily strength was assumed generally fine, were selected to measure the examination for their physical strength compared by age (61-83) and area (big city, medium city, and small city). And the general view that results from the measurement of physical strength of the aged is as follows; First, they maintain constant height and sitting height which occupy the important regions to form the physical strength regardless of their age. Second, the state of weight and ventral girth has decreased outstandingly while the age increased. But the continuous maintenance of a constant weight is essential to keep their physical strength because such decreasing phenomenon is attributed to the sings of decreptitude which comes from natural failing of physical stamina. Third, femoral girth and crural region show a phenomenon to be weakened thinly degree by degree at the age of 70 or afterabout. Fourth, the chest circumference maintains a constant length without a severe change regardless of the increase of age. Fifth, the equilibrium indicates a failing phenomenon by increase of age. Sixth, the motion is agility shows a blunt phenomenon in direct proportion to the increase of age, and the sense to cope with a thing instantaneously shows a rapid descending change of teh ability by the increase of age. Seventh, the lung capacity, a barometer of respiratory function shows an outstanding lowering phenomenon by the increase of age. Putting all results that came from measuring the strength test of the aged together, it can be found in each region that the phenomenon of failing strength does not descend downward quickly by the increase of age, but changes describing an soft curve gradually. To prevent such natural reducing and lowering phenomenon of the aged artificially, a practice which fits the bodily aptitude must be made continuously every day and a stimulation of practice must be given so that the aged could maintain the harmony and balance of body and mind and start a daily work from practice, which would make the aged train themselves from habit. So the best efforts should be done for themselves.

중대뇌동맥 뇌경색 환자에서 고위험군에 관한 비교분석

이재규 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

To select high risk group in middle cerebral artery(MCA) infarction by comparing and analysing 10 risk factors in above patients, we analyzed 32 MCA infarcted patients and 30 case control groups retrospectively. Through the analysis of 10 risk factors(age, heart disease, blood pressure, total cholesterol, triglyceride, HDL-cholesterol, glucose, smoking, r-GTP, past history : hypertension or cerebrovascular accident) in MCA infarction by the times patients arrieves in emergency room by scoring system made by author, MCA infarcted patients showed score about 1.4 in 24 cases(75.00%) among 32 MCA infarction patients, and in control group, score below 1.4 showed in 28 cases(93.33%) among 30 cases By the scoring system made by author, the higher risk grouped patients could identified more easily in emergency department.

古代 Rome의 體育에 관한 考察

金宰圭 단국대학교 1986 論文集 Vol.20 No.-

It is said that the Ancient Rome was the great state unified whole European countries, and Roman culture became a basis of today's western European culture with Greek culture. Rome conquered Greece and ruled Greece for long time, namely, for one thousand years and more. Greek culture, however, soaked in the politics, culture, economy, and society of Rome, and Rome got influenced from Greek culture, and Roman culture was modelled on Greek culture, and was assimilated to Greek culture. Especially, arts and learning were much soakedni and assimilated. Romans praised Greek culture and assimilated to Greek culture. If so, what did the sports of Greece influence upon Rome? On this motive, I set a direction of my studying on the sports of Rome in this theses and have an idea to study on the policy and the faciilities and size of colosseum, and its results comes to the following conclusion. At the beginning of Rome, Romans respected military arts and had a thorough military sprit(militarism). So they were more similar to Spartans than Athenians. The last goal of sports 1vas a means to train soldiers for the purpose of defensing me territory of Rome and expanding the territory. Romans direct1y participated in games and made efforts for national and continuous events as festival games of Greece, but it was failed. But there were a lot of festival games by region in Rome. At the first term of Rome, Rome made all the boys and youths train for purpose of cultivating patience to cold and heat, and practice swimming in rapid stream, and let all the Romans be able to swimm. At the latter term of Rome, the soldiers and professional sportsmen only understood the importance of sports, but general citizens did not understand it, and rulers cruel slaughter, swords, and fight games let the masses despise sports or keep it at a distance. At the latter term, Romans did not make good use of leisure coming from rich living according to the extension of national power and neglected their living because of the avarice of luxury and pleasure. So the dissolute life made national moral degraded, and such bad influence made the athletic field get sick. Accordingly, the sports was professionalized, and fallen down as enjoyable sports. Greeks showed their ability to build temples and tall buildings, but Romans showed their ability to construct big amphitheatres and colosseum, and these were like today's Olympic Main stadium. The colosseum has been proud of its magnificent appearance in the city of Rome, Italy until today. At the latter term of Rome, Romans had a great interest in nation sanitary education to build public bath house at cities in order that they could use them gratis, and they supplied purified city water for the drinking water and bath of citizens. Romans didn't recognize the fact that the physical activities lead harmony Io mind and body, vitality and stimulus to human life, and make our life happy, and they attached importance to military training education only.

古代希臘의 祭典과 體育에 관한 硏究 : olympia 競技大會를 中心으로 Focusing on the Olympic Games

金宰圭 단국대학교 1985 論文集 Vol.19 No.-

Analyzing the physical culture and four grand festivals of the Ancient Greece centeringaround the ancient Olympic games, following conclusions could be drawn. 1. Greece was made up of numerous poleis of various tribes with the common religion andlanguage, and the Greek had absolute faith in the 12 gods, a sort of common gods, dwellingon the Olympus. 2. The Greek believed in the supernatural power of the chief gods dwelling in me sacredprecinct of the Olympus which would bring good or ill luck, fortune or misfortune to man. So they began to build pavilions in the sacred precinct and offered sacrifices to soothe the gods. And they came to hold an athletic game to entertain the gods. 3. The records of the athletes from various participant poleis clearly shows the physical education of Athens and Sparta of which the object was to build up physical strength and harmonized beautiful body. Also military training was carried out for national defense. 4. The Olympic games were held every four years starting when the moon was full following the summer solstice. And an academic, cultural and art event was held simultaneously. 5. When the Olympic games were held, all the war activities were banned and all thepoleis participated in the Olympic games. The truce and cease of might well be cal1ed a grand festival of the whole Greek, a symbol of peace, who loved freedom and democracy. 6. The Olympic games were in pure amateurism at earlier stages, but they turned to professionalism in later period, which were abolished by Theodosius I, a Rome emperor, after the Roman invasion. But the Olympic games in the ancient Greece lasted as long as 112 years from 776 B.C. to 393 A.D.

반대측 선조체에 점삼 출현이 동반된 비케톤성 고혈당성 무도증

이재규,손일홍 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

Hemichorea is usually caused by lesions in the contralateral subthalamus and/or basal ganglia. Brain MRI shows a high signal intensity on T1-weighted images and brain CT shows a hyperdense lesion in the contralateral lentiform nucleus in patients with nonketotic hyperglycemic chorea. It is not unclear that these pathophysiological mechanisms is ischemia or petechial hemorrhage. A 78 year-old woman with uncontrolled diabetic mellitus presented with sudden involuntary movement in the right limbs. Brain CT on the first HD(hospital day) revealed hyperdensity in the left lentiform nucleus and Brain MRI on the 2nd HD showed high signal intensity on Tl-weighted images in the left lentiform nucleus. After 2 month later, involuntrary movment was subsided, and the density was more decreased on follow-up brain CT. We suggest a possibility that nonketotic hyperglycemic hemichorea is associated with petechial hemorrhage in the contralateral lentiform nucleus. 편측무도증은 대부분 반대측 선조체의 문제로 발생된다. 비케톤성 고혈당 편측 무도증을 가지고 있는 환자의 뇌 단층촬영(Brain CT)에서 반대측 선조체의 고음영이 관찰되었고 뇌 자기공명영상(Brain MRI)에서는 T1 강조영상에서 고신호로 강조되었다. 하지만 고혈당과 관련된 편측 무도증의 정확한 기전은 아직도 명확하지 않으며 점상출혈이나 허혈성 변화일 것으로 추정되고 있다. 당뇨가 잘 조절되지 않는 78세 여자환자가 내원 20일전부터 발생한 우측 팔, 다리의 불수의적인 움직임을 주소로 입원하였다. 내원 초기 brain CT에서는 좌측 선조체의 고음영이 관찰되었고 Brain MRI에서는 T1 강조영상에서 고신호를 보였다. 증상 호전 보이면서 추적 관찰한 Brain MRI에서 이 병소는 T1 강조영상에서 고신호 강도가 더욱 증가하였으며, gradient echo에서는 저신호 강도가 더욱 증가하였다. 이후 증상이 더욱 호전되었고, Brian CT에서는 반대측 선조체의 고밀도 소견이 감소한 양상 관찰되어 점상 출혈 기전과 관련된 증례로 추정하여 보고하는 바이다.

Effect of Kaempferol on the Cytotoxicity Induced Oxygen Free Radicals in Skin Fibroblast Derived from Human In Vitro

Jai-Kyoo Lee,Dae-Ho Ha 대한의생명과학회 2008 Biomedical Science Letters Vol.14 No.3

In order to evaluate on the effect of kaempferol on the cytotoxicity of oxygen free radicals, XTT assay was performed to determine the cell viability after skin fibroblasts derived from human (Detroit 51) that were treated with various concentrations of hydrogen peroxide (H₂O₂). And also, the effect of kaempferol on the cytotoxicity induced by H₂O₂ that was examined by cell viability, lactate dehydrogenase (LDH) activity and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity in these cultures. H₂O₂ decreased cell viability in dose-dependent manner in these cultures and the XTT?? and XTT?? values were determined at concentration of 35 μM and 90 μM of H₂O₂ after skin fibroblasts derived from human were treated with 15~90 μM of H₂O₂ for 6 hours, respectively. H₂O₂ was highly toxic on cultured skin fibroblasts derived from human by toxic criteria of Brenfreund and Puerner (1984). In the protective effect of kaempferol on H₂O₂-induced cytotoxicity, kaempferol increased DPPH radical scavenging activity and significantly decreased LDH activity. From these results, it is suggested that oxygen free radical, H₂O₂, was highly toxic on cultured skin fibroblasts derived from human, and also kaempferol of flavonoid showed the protection on H₂O₂-induced cytotoxicity.

Effect of Kaempferol on the Cytotoxicity Induced Oxygen Free Radicals in Skin Fibroblast Derived from Human In Vitro

Lee, Jai-Kyoo,Ha, Dae-Ho 대한의생명과학회 2008 Biomedical Science Letters Vol.14 No.3

In order to evaluate on the effect of kaempferol on the cytotoxicity of oxygen tree radicals, XTT assay was performed to determine the cell viability after skin fibroblasts derived from human (Detroit 51) that were treated with various concentrations of hydrogen peroxide $(H_2O_2)$. And also, the effect of kaempferol on the cytotoxicity induced by H202 that was examined by cell viability, lactate dehydrogenase (LDH) activity and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity in these cultures. $H_2O_2$ decreased cell viability in dose-dependent manner in these cultures and the $XTT_{90}\;and\;XTT_{50}$ values were determined at concentration of $35{\mu}M\;and\;90{\mu}M$ of $H_2O_2$ after skin fibroblasts derived from human were treated with $15{\sim}90{\mu}M$ of $H_2O_2$ for 6 hours, respectively. $H_2O_2$ was highly toxic on cultured skin fibroblasts derived from human by toxic criteria of Brenfreund and Puerner (1984). In the protective effect of kaempferol on $H_2O_2$-induced cytotoxicity, kaempferol increased DPPH radical scavenging activity and significantly decreased LDH activity. From these results, it is suggested that oxygen tree radical, $H_2O_2$, was highly toxic on cultured skin fibroblasts derived from human, and also kaempferol of flavonoid showed the protection on $H_2O_2$-induced cytotoxicity.

Minimum Two-year Results of Revision Total Knee Arthroplasty Following Infectious or Non-infectious Causes

( Kyoung Jai Lee ),( Jae Young Moon ),( Eun Kyoo Song ),( Hong An Lim ),( Jong Keun Seon ) 대한슬관절학회 2012 대한슬관절학회지 Vol.24 No.4

Purpose: To compare clinical outcome of revision total knee arthroplasty (TKA) between the infected and non-infected groups. Materials and Methods: This study compared the clinical and radiographic results of 21 infected and 15 non-infected revision TKAs at a minimum 2- years follow-up. Clinical evaluations were assessed using the range of motion (ROM), Hospital for Special Surgery (HSS) score, Knee Society Knee Score (KSKS), Knee Society Function Score (KSFS), and Western Ontario and McMaster Universities (WOMAC) score. Radiologic evaluations were assessed using the radiographic results of the American Knee Society and joint line change. Results: Patients operated for non-infectious causes had significantly better postoperative ROM than the infected group (infected group, 101.7o; non-infected group, 117.8o). The infected group achieved significantly poor HSS (79.2 vs. 85.5), KSKS (75.5 vs. 86.6), KSFS (76.9 vs. 85.5), WOMAC (30.3 vs. 21.2) scores than the non-infected group. Postoperative joint line elevation was lower in the infected versus non-infected group (0.5 mm vs. 2.1 mm), but there was no significant difference. Conclusions: Revision TKA is an effective treatment that can provide successful results in the infected as well as non-infected patients. The overall results of non-infected revision were more satisfactory than infected revision.

급성 약물중독에 관한 임상적 고찰

이재규,박재황 圓光大學校 醫科學硏究所 1993 圓光醫科學 Vol.9 No.1-2

Clinical observation was made on 405 cases of drug intoxication visited to WonKwang university hospital via emergency room during one year from Jnauary 1991 to December 1991. The results were summarized as follows ; 1. Annual incidence was 1.91% (405 of the 21247 patients). 2. Factors related to increased occurrence were male(53.83%), age of 3rd decade(26.67%), monday (17.78%), and August(17.28%). 3. The motives of most intoxication(88.89%) were suicidal attempts. 4. The most common drug of intoxication was insecticides(36.54%), the remainders were S.T.H.(17.04%), herbicides(11.36%), puffer(5.43%), rodenticides(4.49%), etc. 5. The chief complaints on arrival to emergency room were nausea & vomiting(36.79%), mental change(15.56%), dizziness(13.33%), general weakness(4.49%), etc. 6. The abnormal vital signs on arrival to emergency room were tachycardia(18.52%), mental change (15.56%) hypertension(9.63%), etc. 7. The observed abnormal laboratory findings on admission(27 cases) were elevated ALP(15 cases), leukocytosis(12 cases), depressed T.Protein, depressed HCO_3, hypocarbia etc, in order of frequency. 8. The complications of acute D-I were aspiration pneumonia(2.22%), G-I symtpom(1.23% ; ileus, peptic ulcer, gastritis etc.) parkinsonism(0.74%), etc. 9. The outcomes of the patients were recovery(63.46%), against discharge(26.42%), hopeless discharge(8.15%), death(1.98%)

釣鈞藤이 해마신경세포의 산화적 손상에 미치는 효과

이재규,최유선,이은미,장철호,이강창,박승택,이형철,황상구,주성민,김원신,백은경,전병훈 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.5

To clarify the neurotoxicity of hydrogen peroxide(H2O2) in cultured hippocampal neurons derived from neonatal mouse, cytotoxicity was measured by MTS assay after cultured cells were grown for 5 hours in the media containing 1∼20μM concentrations of H2O2. In addition, the neuroprotective effect of Uncariae Ramulus Cum Uncis was measured in these cultrures. Cell viability was positively decreased in a dose-dependent manner after exposure of cultured mouse hippocampal neurons to 10μM H2O2 for 5 hours. In the neuroprotective effect of Uncariae Ramulus Cum Uncis on H2O2-mediated toxicity, Uncariae Ramulus Cum Uncis prevented the H2O2-induced neurotoxicity in these cultures. From these results, it suggests that H2O2 is toxic in cultured hippocampal neurons derived from neonatal mouse and selective herb extract such as Uncariae Ramulus Cum Uncis is effective in prevetion of the neurotoxicity induced by H2O2.