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Rosado, Lucas de Paula Lopes,Barbosa, Izabele Sales,de Aquino, Sibele Nascimento,Junqueira, Rafael Binato,Verner, Francielle Silvestre Korean Academy of Oral and Maxillofacial Radiology 2019 Imaging Science in Dentistry Vol.49 No.3
Purpose: To compare the diagnostic ability of undergraduate dental students to detect maxillary sinus abnormalities in panoramic radiographs(PR) and cone-beam computed tomography (CBCT). Materials and Methods: This was a retrospective study based on the evaluation of PR and CBCT images. A pilot study was conducted to determine the number of students eligible to participate in the study. The images were evaluated by 2 students, and 280 maxillary sinuses were assessed using the following categories: normal, mucosal thickening, sinus polyp, antral pseudocyst, nonspecific opacification, periostitis, antrolith, and antrolith associated with mucosal thickening. The reference standard was established by the consensus of 2 oral radiologists based on the CBCT images. The kappa test, receiver operating characteristic curves, and 1-way analysis of variance with the Tukey-Kramer post-hoc test were employed. Results: Intraobserver and interobserver reliability showed agreement ranging from substantial (0.809) to almost perfect (0.922). The agreement between the students' evaluations and the reference standard was reasonable (0.258) for PR and substantial(0.692) for CBCT. Comparisons of values of sensitivity, specificity, and accuracy showed that CBCT was significantly better(P<0.05). Conclusion: CBCT was better than PR for the detection of maxillary sinus abnormalities by dental students. However, CBCT should only be requested after a careful analysis of PR by students and more experienced professionals.
Lucas de Paula Lopes Rosado,Izabele Sales Barbosa,Sibele Nascimento de Aquino,Rafael Binato Junqueira,Francielle Silvestre Verner 대한영상치의학회 2019 Imaging Science in Dentistry Vol.49 No.3
Purpose: To compare the diagnostic ability of undergraduate dental students to detect maxillary sinus abnormalities in panoramic radiographs (PR) and cone-beam computed tomography (CBCT). Materials and Methods: This was a retrospective study based on the evaluation of PR and CBCT images. A pilot study was conducted to determine the number of students eligible to participate in the study. The images were evaluated by 2 students, and 280 maxillary sinuses were assessed using the following categories: normal, mucosal thickening, sinus polyp, antral pseudocyst, nonspecific opacification, periostitis, antrolith, and antrolith associated with mucosal thickening. The reference standard was established by the consensus of 2 oral radiologists based on the CBCT images. The kappa test, receiver operating characteristic curves, and 1-way analysis of variance with the Tukey-Kramer post-hoc test were employed. Results: Intraobserver and interobserver reliability showed agreement ranging from substantial (0.809) to almost perfect (0.922). The agreement between the students’ evaluations and the reference standard was reasonable (0.258) for PR and substantial (0.692) for CBCT. Comparisons of values of sensitivity, specificity, and accuracy showed that CBCT was significantly better (P<0.05). Conclusion: CBCT was better than PR for the detection of maxillary sinus abnormalities by dental students. However, CBCT should only be requested after a careful analysis of PR by students and more experienced professionals.
Camila V. Molina,Juliana G. Lima,Izabel C. F. Moraes,Samantha C. Pinho 한국식품과학회 2019 Food Science and Biotechnology Vol.28 No.1
Beta-carotene is an extremely interesting bioactivecompound in the food industry due to its antioxidantcapacity and pro-vitamin A activity. However, its incorporationinto food products can be challenging, as it ishighly hydrophobic and chemically unstable. The aim ofthis study was to evaluate the feasibility of incorporatingbeta-carotene-loaded solid lipid microparticles (SLMs)stabilized with a hydrolyzed soy protein isolate in yogurt. The SLMs were produced using palm stearin as the lipidphase. Microparticle dispersions containing only beta-caroteneand both beta-carotene and alpha-tocopherol wereincorporated into yogurts, comprising 5% of its total mass. This addition itself was efficient to provide color, and thepresence of the lipid microparticles did not change thephysicochemical or the rheological characteristics of theproduct. Based on the sensory evaluation, the panelistsapproved the yogurt, as average grades of global acceptancewere around 8.0 (‘‘liked it very much’’) on thehedonic scale.
Antibacterial Screening of Anthocyanic and Proanthocyanic Fractions from Cranberry Juice
Augusto Cesar C. Spadaro,Denise P.S. Leit?,Ana Cristina M. Polizello,Izabel Y. Ito 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.1
The effect of anthocyanin- and proanthocyanidin-rich fractions isolated from cranberry juice was studied fortheir antibacterial activity against nine bacterial strains. Activity was assessed by the agar diffusion assay. Staphylococcus au-reusATCC 6538 was the only strain to exhibit some susceptibility to four out of 10 anthocyanin-rich fractions tested. A vari-able susceptibility of S. aureus, Enterococcus faecalisATCC 10541, and Micrococcus luteusATCC 9341 to proanthocyani-din-rich fractions was also observed. Streptococcus mutansstrains as well as Escherichia coliATCC 10538 and PseudomonasaeruginosaATCC 27853 were not susceptible to any of the cranberry juice samples or fractions at the tested concentrations.There was no clear correlation between Gram-positive or Gram-negative bacterial susceptibility to cranberry juice. In thiswork, the role of cranberry juice anthocyanic and proanthocyanic fractions upon bacterial viability is discussed.
Terrabuio, Bianca Rodrigues,Carvalho, Caroline Gomes,Peralta-Mamani, Mariela,da Silva Santos, Paulo Sergio,Rubira-Bullen, Izabel Regina Fischer,Rubira, Cassia Maria Fischer Korean Academy of Oral and Maxillofacial Radiology 2021 Imaging Science in Dentistry Vol.51 No.2
Purpose: This study was conducted to review the literature regarding the types of cone-beam computed tomography (CBCT) artifacts around dental implants and the factors that influence their formation. Materials and Methods: A search strategy was carried out in the PubMed, Embase, and Scopus databases to identify published between 2010 and 2020, and 9 studies were selected. The implants included 306 titanium, titanium-zirconium, and zirconia implants, as well as 5 titanium cylinders. Results: The artifacts around the implants were the beam-hardening artifact, the streaking artifact, and band-like radiolucent areas. Some factors that influenced the formation of artifacts were the implant material, bone type, evaluated regions, distance, type of CBCT, field of view (FOV) size, milliamperage, peak kilovoltage (kVp), and voxel size. The beam-hardening artifact was the most widely reported, and it was minimized in protocols with a smaller FOV, larger voxels, and higher kVp. Conclusion: The risk and benefit of these protocols in individuals with dental implants must be considered, and clinical examinations and complementary radiographs play an essential role in implantology.
Mairim Russo Serafini,Rodrigo Correia Santos,Adriana Gibara Guimarães,João Paulo Almeida dos Santos,Alan Diego da Conceicão Santos,Izabel Almeida Alves,Daniel Pens Gelain,Paulo Cesar de Lima Nogueira 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.10
Herbal drugs have been used since ancient times to treat a wide range of diseases. Morinda citrifolia Linn (popularly known as “Noni”) has been used in folk medicine by Polynesians for over 2,000 years. It is reported to have a broad range of therapeutic effects, including effects against headache, fever, arthritis, gingivitis, respiratory disorders, infections, tuberculosis, and diabetes. The aim of this study was to investigate the antioxidant, anti-inflammatory, antinociceptive, and antibacterial properties of the aqueous extract from M. citrifolia leaves (AEMC). Antioxidant activity was observed against lipid peroxidation, nitric oxide, and hydroxyl radicals. The antinociceptive effect of AEMC was observed in the acetic acid–induced writhing test at the higher dose. Moreover, AEMC significantly reduced the leukocyte migration in doses of 200 and 400 mg/kg and showed mild antibacterial activity. Together, the results suggest that properties of M. citrifolia leaf extract should be explored further in order to achieve newer tools for managing painful and inflammation conditions, including those related to oxidant states.
de Carvalho, Bruno Reis,Ferreira Junior, Helvio da Cruz,Viana, Gabriel da Silva,Alves, Warley Junior,Muniz, Jorge Cunha Lima,Rostagno, Horacio Santiago,Pettigrew, James Eugene,Hannas, Melissa Izabel Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.11
Objective: A trial was conducted to investigate the effects of supplemental levels of Mn provided by organic and inorganic trace mineral supplements on growth, tissue mineralization, mineral balance, and antioxidant status of growing broiler chicks. Methods: A total of 500 male chicks (8-d-old) were used in 10-day feeding trial, with 10 treatments and 10 replicates of 5 chicks per treatment. A 2×5 factorial design was used where supplemental Mn levels (0, 25, 50, 75, and 100 mg Mn/kg diet) were provided as MnSO<sub>4</sub>·H<sub>2</sub>O or MnPro. When Mn was supplied as MnPro, supplements of zinc, copper, iron, and selenium were supplied as organic minerals, whereas in MnSO<sub>4</sub>·H<sub>2</sub>O supplemented diets, inorganic salts were used as sources of other trace minerals. Performance data were fitted to a linearbroken line regression model to estimate the optimal supplemental Mn levels. Results: Manganese supplementation improved body weight, average daily gain (ADG) and feed conversion ratio (FCR) compared with chicks fed diets not supplemented with Mn. Manganese in liver, breast muscle, and tibia were greatest at 50, 75, and 100 mg supplemental Mn/kg diet, respectively. Higher activities of glutathione peroxidase and superoxide dismutase (total-SOD) were found in both liver and breast muscle of chicks fed diets supplemented with inorganic minerals. In chicks fed MnSO<sub>4</sub>·H<sub>2</sub>O, ADG, FCR, Mn balance, and concentration in liver were optimized at 59.8, 74.3, 20.6, and 43.1 mg supplemental Mn/kg diet, respectively. In MnPro fed chicks, ADG, FCR, Mn balance, and concentration in liver and breast were optimized at 20.6, 38.0, 16.6, 33.5, and 62.3 mg supplemental Mn/kg, respectively. Conclusion: Lower levels of organic Mn were required by growing chicks for performance optimization compared to inorganic Mn. Based on the FCR, the ideal supplemental levels of organic and inorganic Mn in chick feeds were 38.0 and 74.3 mg Mn/kg diet, respectively.
de Souza Tolentino, Elen,Andres Amoroso-Silva, Pablo,Alcalde, Murilo Priori,Yamashita, Fernanda Chiguti,Iwaki, Lilian Cristina Vessoni,Rubira-Bullen, Izabel Regina Fischer,Duarte, Marco Antonio Hungar Korean Academy of Oral and Maxillofacial Radiology 2021 Imaging Science in Dentistry Vol.51 No.1
Purpose: This study was performed to compare the ability of limited- and large-volume cone-beam computed tomography (CBCT) to display isthmuses in the apical root canals of mandibular molars. Materials and Methods: Forty human mandibular first molars with isthmuses in the apical 3 mm of mesial roots were scanned by micro-computed tomography (micro-CT), and their thickness, area, and length were recorded. The samples were examined using 2 CBCT systems, using the smallest voxels and field of view available for each device. The Mann-Whitney, Friedman, and Dunn multiple comparison tests were performed (α=0.05). Results: The 3D Accuitomo 170 and i-Cat devices detected 77.5% and 75.0% of isthmuses, respectively (P>0.05). For length measurements, there were significant differences between micro-CT and both 3D Accuitomo 170 and i-Cat(P<0.05). Conclusion: Both CBCT systems performed similarly and did not detect isthmuses in the apical third in some cases. CBCT still does not equal the performance of micro-CT in isthmus detection, but it is nonetheless a valuable tool in endodontic practice.