Para-Chlorophenylalanine이 흰쥐 췌장 외분비부분 샘포세포에 미치는 영향에 대한광학 및 전자현미경적 연구

김인구,정영길,최창도,최월봉 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.3

環境保全을 爲한 生態系 基本調査 硏究

姜寅求 동국대학교 대학원 1985 大學院硏究論集-東國大學校 大學院 Vol.15 No.-

This study was carried out to give basic information about pertinent green space management in industrial area, Ulsan which has being airpolluted. Recent research on The interaction between plants and air pollution was briefly reviewed. Total and annual biomass yield, leaf surface area, net assimilation rate, total sulfur content in foliages and visible injury were examined between various plant species and between the two regions which are airpolluted severely and lightly, respectively. The results obtained were as follows: 1. The vegetations including trees and agronomic crops were sparsely distributed around the industrial area in Ulsan. Among them, Pinus thunbergii, Pinus densiflora, Pinus rigida Alnus hirsuta and Quercus acutissima were major tree species producing poor yield. 2. In lightly polluted areas (Seongan and Bukjeong), P. rigida, P. thunbergii, P. densiflora, Q. acutissima, A. hirsuta and Robinia pseudoacacia showed good biomass yield in descending order, while P. densiflora, R. pseudoacacia, P. rigida and P. thunbergii did less yield in severely polluted areas(Yaeaum and Yeochon) 3. A. hirsuta and R. pseundoacacia among deciduous trees produced large leaf areas whereas P. thunbergii, P. rigida and P. densiflora were the best among coniferous trees. 4. Net assimiltion rate of trees growing in Seongan and Bukjeong areas was higher than that in Yaeaum and Yeochon areas 5. Trees growing in Yaeaum and Yeochon areas showed higher total sulfur contents in leaves than those in Seongan and Bukjeong areas. 6. Studied biomass yields indicated larger in the less polluted areas of Seongan and Bukjeong where vegetations are richer than the more polluted areas. 7. Total anounts of dry matter biomass produced from Ulsan area were estimated to be 150,714.68 tons. Annual production of dry matter biomass amounts to be 35,804.62 tons. Estimated amount for O_2 produced annually from the vegetated area(11.179ha) in Ulsan was 37,959.9 tons while that for SO_2 was 45.07 tons. 8. Low annual yield of biomass in Ulsan, in generel, was due mainly to worse environmental conditions. Thus, a further study is urgently needed for better management of green space as well as pollution control in Ulasn area.

순산소 순환유동층에서 로내 탈황 및 탈질법 적용에 따른 오염물질 거동특성

최경구(Gyung-Goo Choi),나건수(Geon-Soo Na),신지훈(Ji-Hoon Shin),길상인(Sang-In Keel),이정규(Jung-Kyu Lee),허필우(Pil-Woo Heo),윤진한(Jin-Han Yun) 한국청정기술학회 2018 청정기술 Vol.24 No.3

순산소 연소기술은 화력발전에 적용 가능한 유망한 온실가스 감축 기술로 평가되고 있다. 본 연구는 환경적 관점에서 순환유동층을 활용한 순산소 연소조건에 로 내 탈황 및 탈질법을 적용하여 NO 및 SO₂의 거동을 살펴보는 한편, SO₃, NH₃, 그리고 N2O의 발생 경향도 관측하였다. 이를 위해, 연소로 내 석회석 및 요소수를 투입하였다. 로 내 탈황법은 연소가스 내 SO₂ 농도를 ~403에서 ~41 ppm까지 저감하였다. 또한 SO₃ 형성의 주원료인 SO₂가 저감되면서 연소가스 내 SO₃ 농도도 ~3.9에서~1.4 ppm까지 감소되었다. 그러나 석회석 내 CaCO₃가 NO의 발생을 촉진하는 현상도 관측되었다. 연소가스 내 NO 농도는로 내 탈질법을 적용하여 ~26 - 34 ppm까지 저감되었다. 요소수 투입량 증가에 따라 연소가스 내 NH₃ 농도가 증가하여 최대~1.8 ppm으로 나타났으며, N₂O의 농도도 ~61에서 ~156 ppm까지 증가하였다. N₂O 발생량 증가 현상은 요소수의 열분해 과정에서 생성된 HNCO가 N₂O로 전환되어 나타난다. 본 연구의 결과를 통해 로 내 연소가스 세정법을 적용할 경우 NOx 및 SOx의 저감뿐만 아니라, 다른 오염물질의 발생에 대한 주의가 필요할 것으로 보인다. Oxy-fuel combustion is considered as a promising greenhouse gas reduction technology in power plant. In this study, the behaviors of NO and SO₂ were investigated under the condition that in-furnace deNOx and deSOx methods are applied in oxy-fuel circulating fluidized bed combustion condition. In addition, the generation trends of SO₃, NH₃ and N2O were observed. For the purpose, limestone and urea solution were directly injected into the circulating fluidized bed combustor. The in-furnace deSOx method using limestone could reduce the SO₂ concentration in exhaust gas from ~403 to ~41 ppm. At the same experimental condition, the SO₃ concentration in exhaust gas was also reduced from ~3.9 to ~1.4 ppm. This trend is mainly due to the reduction of SO₂. The SO₂ is the main source of the formation of SO₃. The negative effect of CaCO₃ in limestone, however, was also appeared that it promotes the NO generation. The NO concentration in exhaust gas reduced to ~26 - 34 ppm by appling selective non-catalytic reduction method using urea solution. The NH₃ concentration in exhaust gas was appeared up to ~1.8 ppm during injection of urea solution. At the same time, the N₂O generation also increased with increase of urea solution injection. It seems that the HNCO generated from pyrolysis of urea converted into N₂O in combustion atmosphere. From the results in this study, the generation of other pollutants should be checked as the in-furnace deNOx and deSOx methods are applied.

Kainic Acid로 처리한 해마박편배양 마우스 간질모델에서 치아이랑 Parvalbumin 면역 반응성 사이신경세포의 형태학적 변화

정희선,신미영,김영훈,이인구,황경태,김명석 대한소아과학회 2002 小兒科 Vol.45 No.12

포항지역 고3 남학생들의 생활습관과 성적, 스트레스에 관한 연구

김인태,이동욱,이인구,성낙진,박기흠 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.2

목적 : 우리나라의 고등학교 3학년 학생들은 대학입시를 앞두고 많은 스트레스 환경에 놓여있으나, 그에 대한 연구는 충분하지 않았다. 본 연구는 고등학교 3학년 남학생들을 대상으로 생활습관과 스트레스 정도, 스트레스 대처방법을 알아보고 생활습관과 스트레스, 성적과의 상호 관계를 살펴보고자 하였다. 대상 및 방법 : 수능시험을 치른 포항 모 남자 고등학교 3학년 454명을 대상으로 2000년 11월 29일 자기 기입식 설문지를 이용하여 성적, 스트레스량, 스트레스 해소방법을 조사하였다. 스트레스 측정은 외래용 스트레스량 측정도구인 BEPSI (The Brief Encounter Psychosocial Instrument) 번역판을 사용하였다. 결과 : 조사대상자의 성적과 생활습관과의 관계를 본 결과 생활습관 중에서 아침식사(p<0.05), 규칙적인 식사(p<0.01), 규칙적인 수면(P<0.01), 부모와의 대화(P<0.05), 흡연(P<0.05)이 성적과 통계적으로 유의하였다. BEPSI 점수는 성적 및 스트레스 해소방법과 유의한 관계가 없었다. 생활습관과 BEPSI 점수와의 관계는 규칙적인 식사(P<0.05), 부모와의 대화(P<0.05), 주 2회 이상의 음주(P<0.01), 흡연(P<0.01) 등에서 통계적으로 유의한 관계가 있었다. 건강 생활습관 갯수와 BEPSI 점수는 유의한 관계가 있었다(P<0.01). 결론 : 고3 남학생들은 건강한 생활습관과 학교성적이 비례하였고, 건강습관 갯수와 스트레스량은 역비례하였다. 그러므로 고등학교 3학년 시기에는 좋은 생활습관을 가지는 것이 중요하다. Background: There are many stressful environment in the twelfth grade students who will take an entrance examination. But the investigation about twelfth grade students were not studied enough. Therefore we investigated the relationship between life style, school record and stress in the twelfth grade students. Methods: In November 29,2000, we surveyed 454 twelfth grade male students who has taken entrance examination for a university in a high school located in Pohang. Self report questionnaire was administered to measure school record, coping method, life style and stress. Stress amount was measured by Korean-translated BEPSI score. Results: There was significant relationship between school record and life style such as breakfast. regular diet, regular sleep, enjoy conversation with their parents and smoking. School record and coping method were no significant relationship with BEPSI scores. There was significant relationship between BEPSI scores and life style such as regular diet, enjoy conversation with their parents, smoking, drinking more than two times a week. The number of healthy life styles number was significantly related to BEPSI scores. Conclusions: Healthy life style was proportional to good school record and inversely proportional to stress amount in twelfth grade male students. Therefore, we conclude that it is important to keep healthy life style in the twelfth grade.

Impact of the Metabolic Syndrome on the Clinical Outcome of Patients with Acute ST-Elevation Myocardial Infarction

Lee, Min Goo,Jeong, Myung Ho,Ahn, Youngkeun,Chae, Shung Chull,Hur, Seung Ho,Hong, Taek Jong,Kim, Young Jo,Seong, In Whan,Chae, Jei Keon,Rhew, Jay Young,Chae, In Ho,Cho, Myeong Chan,Bae, Jang Ho,Rha, S The Korean Academy of Medical Sciences 2010 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.25 No.10

<P>We sought to determine the prevalence of metabolic syndrome (MS) in patients with acute myocardial infarction and its effect on clinical outcomes. Employing data from the Korea Acute Myocardial Infarction Registry, a total of 1,990 patients suffered from acute ST-elevation myocardial infarction (STEMI) between November 2005 and December 2006 were categorized according to the National Cholesterol Education Program-Adult Treatment Panel III criteria of MS. Primary study outcomes included major adverse cardiac events (MACE) during one-year follow-up. Patients were grouped based on existence of MS: group I: MS (n=1,182, 777 men, 62.8±12.3 yr); group II: Non-MS (n=808, 675 men, 64.2±13.1 yr). Group I showed lower left ventricular ejection fraction (LVEF) (<I>P</I>=0.005). There were no differences between two groups in the coronary angiographic findings except for multivessel involvement (<I>P</I>=0.01). The incidence of in-hospital death was higher in group I than in group II (<I>P</I>=0.047), but the rates of composite MACE during one-year clinical follow-up showed no significant differences. Multivariate analysis showed that low LVEF, old age, MS, low high density lipoprotein cholesterol and multivessel involvement were associated with high in-hospital death rate. In conclusion, MS is an important predictor for in-hospital death in patients with STEMI.</P>

서방형 Diltiazem제제의 개발을 위한 약동학/약력학적 특성 검토

유경상,배균섭,조주연,장인진,신상구 大韓臨床藥理學會 1998 臨床藥理學會誌 Vol.6 No.2

녹동균 세포외막 단백질 백신 CFC-1-101의 안정성 및 면역원성 검토 : 임상 제 Ⅰ/Ⅱa상 시험

장인진,김익상,유경상,임동석,김형기,신상구,장우현,박완제,이나경,정상보,안동호,조양제,안보영,이윤하,김영지,남성우,김현수 대한감염학회 1998 감염 Vol.30 No.3

목적 : 제일제당에서는 녹농균의 세포외막 단밸질을 유효성분으로 하는 백신인 CFC-101을 개발하였으며, 동물시험에서 이 백신의 안전성과 유효성을 입증하였다. 본 연구에서는 이 녹농균 백신의 인체에 대한 안전성과 면역원성을 평가하는 동시에 인체 접종시의 최적 투여 용량을 결정하기 위하여 제 I/Ⅱa상 임상시험을 수행하였다. 방법 : 건강한 성인 남자를 피험자로 선별하여 각 용량군에 백신투여자 6명, 위약투여자 2명을 배정하였다. 백신 투여군은 0.25mg, 0.5mg 또는 1.0mg 용량의 녹농균 백신을 7일 간격으로 3회에 걸쳐 근육주사 하였으며, 위약 투여군에게는 세포외막 단백질을 제외한 동일한 성분을 투여하였다. 백신접종 후 국소적 또는 전신적인 반응의 발생여부를 관찰하고, 혈액시료를 체취하여 백신의 역가와 유효성을 검정하였다. 결과 : 녹농균 백신 CFC-101은 모든 접종자에서 양호한 내약성을 보였다. 또한 0.5mg 과 1.0mg 백신 투여군에서는 100%의 항체양전율을 나타내었다. 생성된 항체는 녹농균 세포외막단백질에 특이성을 보였고, 녹농균 감염에 대해 방어효능이 있었다. 결론 : 이와같은 결과로부터 이 녹농균 백신은 인체에 안전하게 투여할 수 있으며, 높은 항체 생성능으로 감염방어 효능을 보이고 0.5mg과 1.0mg이 최적용량인 것으로 판단되었다. Background : We developed a Pseudomonas aeruginosa outer membrane protein(OMP) vaccine CFC-101, and the prophylactic efficacy of which has been demonstrated in animal models. In order to evaluate the safety and immunogenicity of the P. aeruginosa vaccine, we carried out a phase I/Ⅱa clinical trial in healthy male volunteers. Methods : Groups of eight volunteers, including two placebo subjects, were vaccinated intramuscularly with three doses of 0.25, 0.5 or 1.0 mg of the vaccine at one week intervals. Sings of systemic and local reactions observed after vaccination were recorded for each vaccinee for 5 days. Physical examinations were performed on days 0, 1, 7, 8, 14, 15, 21, and 42, and clinical laboratory tests were done on days 0, 3, and 21. Blood samples for assay of serum antibody levels were obtained up to 42 days after the first vaccination. Results : The vaccine was generally well tolerated by all vaccinees, showing no significant side effects. In the three dosage groups, all vaccinees, except one receiving the 0.25 mg dose, showed significant elevation in serum IgG antibody titers against the vaccine proteins, indicating 100% seroconversion in 0.5 and 1.0 mg groups. The human antibodies induced by the vaccine were specific for P. aeruginosa OMPs, as confirmed by western blot analysis and immunoprecipitation assays. The capacity of the human antisera to enhance opsonophagocytic killing activity by polymorphonuclear leukocytes and to confer protection against P. aeruginosa infections indicates that the antibodies elicited by the vaccine have protective efficacy. Conclusion : We conclude that the P. aeruginosa OMP vaccine is safe and effective for human use and its optimal dose to be 0.5 or 1.0 mg.

지능형 기업신용평가 시스템의 개발

한인구(In Goo Han),권영식(Young Sig Kwon),이건창(Kun Chang Lee) 한국경영학회 1995 經營學硏究 Vol.24 No.4

Credit rating represent an assessment of the relative level of risk associated with the timely payments required by the debt obligations. Credit rating is essential for the capital market to works efficiently. The results of credit rating by a professional agency are major criteria to banks` decision of loans and their terms. There are three domestic credit rating agencies. They use judgmental methodology rather than scientific and quantitative tools. In the period of economic liberalization, more attention is paid to the development of scientific credit rating system. The traditional techniques for creidit rating are statistical models such as MDA, probit, and logit. Artificial intelligence techniques such as inductive learning and neural network have been applied for credit rating since late 1980`s. In this research, we developed NICE-AI, which is the first credit rating system based on the neural network models. NICE-AI is available in the commercial information service, NICE-TIPS by National Information & Credit Evaluation In.

美國 各 大學의 體育館 施設 實態 調査硏究

金相九,姜仁燮 成均館大學校 科學技術硏究所 1984 論文集 Vol.35 No.1

For the purpose of investigation of the actual condition of each university gymnasium in U.S.A., I had visited directly there and investigated a number of documents. The conclusions are as follows. 1. Gymnasium facilities The athletic facilities of university are devided into four blocks; a playground, a gymnasium, a pool and a recreation center. Especially, I think that we must build a multi-purpose highstoried gymnasium which is constituted for special program. That is, theb asement should be constituted with pool and its supplementary facilities; the 1st story be constituted for the place of gymnastics, training, dancing, and tool lending; the 2nd story constituted with a great stadium for various sporting events and electromotive stand enlarging spectator scats as occasion demands; the 3rd story mainly a study room, a laboratory, a broadcasting studio, a photographing room, a conference room, which mint be used for school education, extraordinary athleticactvites, recreation, international games, the functions of local community. 2. Operation of Recreation Center Recreation center must take a administrative office, which should administrate programs about indvidual activites, intramural sports, club sports, instruction classes, recreation areas, the functions of public welfare facilities of school headed by the function of inside or outside the school. So I think a rational system is necessary in order to administrate them efficiently, the center should be administrated by the membership fee using the facilities. 3. Unification of School Athletic and. Social One I think that athletic facilities must be a social center of the organization of new inhibitant's space in modern world city space. In order to get effects, from the viewpoint of whole life education as being united of school education and social one, the facilities should be openel to the public as a place of physical activites or recreation after school hours or in holiday. Ultimately, I think that the balanced development of school education and social one through athletic activities will do positive role to accomplish a better society.