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Preparation of gas-atomized Fe-based alloy powders and HVOF sprayed coatings
Chau, Joseph Lik Hang,Pan, Alfred I-Tsung,Yang, Chih-Chao Techno-Press 2017 Advances in materials research Vol.6 No.4
High-pressure gas atomization was employed to prepare the Fe-based $Fe_{50}Cr_{24}Mo_{21}Si_2B_3$ alloy powder. The effect of flow rate of atomizing gas on the median powder diameter was studied. The results show that the powder size decreased with increasing the flow rate of atomizing gas. Fe-based alloy coatings with amorphous phase fraction was then prepared by high velocity oxygen fuel spraying (HVOF) of gas atomized $Fe_{50}Cr_{24}Mo_{21}Si_2B_3$ powder. Microstructural studies show that the coatings present dense layered structure and low porosity of 0.17% in about $200{\mu}m$ thickness. The Fe-based alloy coating exhibits an average hardness of about 1230 HV. Our results show that the HVOF process results in dense and well-bonded coatings, making it attractive for protective coatings applications.
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Kim, S.H.,Chau, G.C.,Jang, Y.H.,Lee, S.I.,Pyo, S.,Um, S.H. W. B. Saunders Co ; Centrum Philadelphia 2013 Human pathology Vol.44 No.2
Mammalian target of rapamycin (mTOR) has emerged as a key regulator of cell metabolism, growth, and proliferation. Despite the increasing significance of mTOR signaling in cancer cell cycle and proliferation, the clinical significance of activated mTOR in esophageal squamous cell carcinoma and its role in esophageal cancer cell proliferation and invasion remain unclear. Here, we show that both high levels of phosphorylated-mTOR and an increased ratio of phosphorylated-mTOR/mTOR (ratio ≥0.2) were significantly associated with shortened disease-specific survival in 165 patients with esophageal squamous cell carcinoma in univariate analysis (P = .047 for phosphorylated-mTOR, P = .021 for phosphorylated-mTOR/mTOR); phosphorylated-mTOR and phosphorylated-mTOR/mTOR remained independent prognostic factors after adjusting for age, TNM stage, chemotherapy, and radiation therapy in multivariate analysis (hazard ratio, 1.67, P = .025 for phosphorylated-mTOR; hazard ratio, 1.95, P = .006 for phosphorylated-mTOR/mTOR). Moreover, down-regulation of mTOR or mTOR complex components led to attenuation of proliferation, migration, and invasion of esophageal squamous cell carcinoma cell lines through suppression of cyclin D1 expression. Collectively, our findings suggest that phosphorylated-mTOR and the ratio of phosphorylated-mTOR/mTOR are closely linked to tumor progression and represent independent prognostic factors in esophageal squamous cell carcinoma, thereby providing a potential therapeutic target for this malignancy.
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An Energy Harvester Based on a Bistable Origami Mechanism
Tien-Hoang Ngo,I-Ting Chi,Minh-Quang Chau,Dung-An Wang 한국정밀공학회 2022 International Journal of Precision Engineering and Vol.23 No.2
This paper describes a vibration energy harvester based on an origami mechanism through piezoelectric energy conversion. The device is capable of broadband energy harvesting from low frequency ambient vibrations. This design utilizes bistability inherent in the waterbomb base origami structure to increase the bandwidth of its frequency response. The folding along the crease pattern of the origami mechanism can facilitate large bending deformations of piezoelectric films to generate high electric power output. The compact size and light weight of the origami mechanism render it convenient for integration into various hosts subjected to vibrations. Performance of the origami mechanism is investigated under external excitations with various vibration magnitudes and acceleration levels. This work demonstrates a scheme of broadband vibration energy harvesting by integration of an origami structure with piezoelectric materials. A high fractional bandwidth of 40% is attained under a sinusoidal excitation with a peak acceleration of 0.1 g.
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A study on pushover analyses of reinforced concrete columns
Kuang-Yen Liu,Chin-Kuo Su,I-Chau Tsai,Yu-Chi Sung,Kuo-Chun Chang 국제구조공학회 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.21 No.1
This paper proposes a realistic approach to pushover analyses of reinforced concrete (RC) structures with single column type and frame type. The characteristic of plastic hinge of a single RC column subjected to fixed axial load was determined first according to column’s three distinct failure modes which were often observed in the experiments or earthquakes. By using the determined characteristic of plastic hinge, the pushover analyses of single RC columns were performed and the analytical results were investigated to be significantly consistent with those of cyclic loading tests. Furthermore, a simplified methodology considering the effect of the variation of axial force for each RC column of the frame structure during pushover process is proposed for the first time. It would be helpful in performing pushover analysis for the structures examined in this study with efficiency as well as accuracy.
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A study on pushover analyses of reinforced concrete columns
Sung, Yu-Chi,Liu, Kuang-Yen,Su, Chin-Kuo,Tsai, I-Chau,Chang, Kuo-Chun Techno-Press 2005 Structural Engineering and Mechanics, An Int'l Jou Vol.21 No.1
This paper proposes a realistic approach to pushover analyses of reinforced concrete (RC) structures with single column type and frame type. The characteristic of plastic hinge of a single RC column subjected to fixed axial load was determined first according to column's three distinct failure modes which were often observed in the experiments or earthquakes. By using the determined characteristic of plastic hinge, the pushover analyses of single RC columns were performed and the analytical results were investigated to be significantly consistent with those of cyclic loading tests. Furthermore, a simplified methodology considering the effect of the variation of axial force for each RC column of the frame structure during pushover process is proposed for the first time. It would be helpful in performing pushover analysis for the structures examined in this study with efficiency as well as accuracy.
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