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Multi-scalar Dynamics of Cluster Development : The Role of Policies in Three Korean Clusters
Hyungjoo Kim(김형주),Jeong Hyop Lee(이정협) 대한지리학회 2009 대한지리학회지 Vol.44 No.5
This paper critically examines cluster dynamics and development in a multi-scalar approach, criticizing both the argument overemphasizing local networks and endogenous development for regional development and the contention highlighting global networks and the role of global players. We argue that state policies, exogenous and direct, play a significant part in cluster dynamics and development especially in the case of Korea where the state government’s strong policies have led to rapid industrialization. We analyze multi-scalar factors, especially the government policies at a national level, in the development paths of the three cases including Ulsan automobile cluster, Daedeok research cluster, and Dongdaemun fashion cluster. 본 연구는 클러스터의 역동성과 발전과정을 다규모적 접근법으로 분석하였다. 지역발전에서 지역 내부의 네트워크와 내생적 발전을 강조한 논의나 글로벌 네트워크와 조직의 역할을 강조한 논의는 모두 한계를 가지며, 외부적이고 직접적인 국가 정책이 클러스터의 역동성과 발전 과정에 미치는 역할은 과소평가되었다. 특히 강력한 정부 정책이 급속한 산업화를 이끌어온 한국의 경우 클러스터의 발전 과정에서도 국가 정책이 중요한 역할을 했다. 울산 자동차 클러스터, 대덕 연구 클러스터, 동대문 패션 클러스터의 사례에서 그 생성과 발전과정에 영향을 미친 지역 차원, 글로벌 차원의 다양한 요인들과 함께 국가 정책의 영향이 분석되었다.
Role of the CCN protein family in cancer
( Hyungjoo Kim ),( Seogho Son ),( Incheol Shin ) 생화학분자생물학회(구 한국생화학분자생물학회) 2018 BMB Reports Vol.51 No.10
The CCN protein family is composed of six matricellular proteins, which serve regulatory roles rather than structural roles in the extracellular matrix. First identified as secreted proteins which are induced by oncogenes, the acronym CCN came from the names of the first three members: CYR61, CTGF, and NOV. All six members of the CCN family consist of four cysteine-rich modular domains. CCN proteins are known to regulate cell adhesion, proliferation, differentiation, and apoptosis. In addition, CCN proteins are associated with cardiovascular and skeletal development, injury repair, inflammation, and cancer. They function either through binding to integrin receptors or by regulating the expression and activity of growth factors and cytokines. Given their diverse roles related to the pathology of certain diseases such as fibrosis, arthritis, atherosclerosis, diabetic nephropathy, retinopathy, and cancer, there are many emerging studies targeting CCN protein signaling pathways in attempts to elucidate their potentials as therapeutic targets. [BMB Reports 2018; 51(10): 486-492]