고공 및 지상 방사능 측정 성적에 관한 소고

차재철,문형남,김형철 공군본부 의무감실 1970 항공의학 Vol.18 No.1-2

비혈연간 조혈모세포이식 후 재발한 만성골수성백혈병에서 Gleevec에 의한 완전관해 및 공여자 조혈 재건 1예

박사라,김우건,이제환,최성준,형철호,손희정,강혜진,지형석,이정신,이규형 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.2

저자들은 만성골수성백혈병으로 동종 골수이식 후 림프구성급성전환으로 재발한 환자에서, Gleevec 투약 후 DLI (donor lymphocyte infusion) 없이 공여자 조혈(donor hematopoiesis)의 재건이 이루어지고, 세포유전학적, 분자생물학적 기준에서 모두 완전관해에 이르고, 12개월째 관해를 유지하고 있는 환자를 경험하였기에 이를 보고하는 바이다. 본례의 환자에서 Gleevec은 동종 골수이식 후 급성전환기로 재발한 환자에서도 매우 효과적인 것으로 나타났다. Gleevec은 동종 골수이식 후 재발한 만성골수성백혈병에서 Interferon-α, DLI, 2차골수이식 등 기존의 치료의 문제점을 보완할 수 있는 유용한 치료방법으로 사용될 수 있을 것으로 생각되며, 이의 장기적 치료효과의 평가와 기존치료와의 병합요법의 유용성 등에 대한 향후 연구가 필요할 것으로 생각된다. We report a 32-year old woman with chronic myelongenous leukemia (CML) in lymphoid blast crisis, who underwent allogenic bone marrow transplantation (BMT) from HLA phenotype full mached unrelated donor. Her disease relapsed into full-blown blast crisis. Upon treatment with gleevec, she achieved immediate remission of leukemia as well as the donor type hematopoiesis without donor lymphocyte infusion (DLI). Our case suggests the high effectiveness of gleevec in CML relapsed after allogeneic BMT. Further studies are needed to define the role of gleevec (with or without DLI) in the management of CML relapsed after allogeneic BMT.

납착 방법이 치과용 금속의 성상에 미치는 영향에 관한 연구

김철형,송영균,이종혁 대한치과보철학회 2012 대한치과보철학회지 Vol.50 No.1

연구 목적: 본 연구는 치과영역에서 많이 사용되는 비귀금속 합금인 니켈-크롬 합금을 산소-아세틸렌 불꽃 납착법과 적외선 용접법을 이용해 용접하고 용접부 및 그 주변을 광학 현미경과 EPMA (Electron Probe Micro Analyzer, 전자미세현미분석기)를 통해 관찰하여 용접방법이 금속의 성상(性狀)에 미치는 영향을 조사하였다. 연구 재료 및 방법:니켈-크롬 합금을 이용하여 3.0 mm 직경, 30 mm 길이의 시편을 제작하였다. 시편은 산소-아세틸렌 불꽃 납착법, 적외선 용접법의 두 개의 그룹으로 분류하였다(n = 4). 시편을 low-speed disc로 자른 후 각각을 산소-아세틸렌 토치와 적외선 용접기를 이용해 용접하였다. 용접과 마무리 후에 시편을 광학현미경으로 용접부, 5 mm 떨어진 지점, 10 mm 떨어진 지점의 3개 부위에서 관찰하고EPMA를 이용하여 분석하였다. 결과: 광학 현미경 관찰 결과 용접부에서는 두 방법 모두 다수의 파절선이 관찰되었고, 10.0 mm 떨어진 거리에서는 두 방법 모두 시편의 표면에서 파절선이 발견되지 않았으나 5.0 mm 떨어진 거리에서는 적외선 용접법에서는 시편의 표면이 다소 거칠기는 했으나 파절선은 발견되지 않았고 산소-아세틸렌 불꽃 납착 표면에서는 다수의 파절선이 관찰되었다. EPMA분석에서 적외선 용접법에 의한 방법에서는 용접부위, 5.0 mm 떨어진 부위, 10.0 mm 떨어진 부위 모두에서 시편 금속의 구성성분 비율이 제조사의 구성성분 비율과 10.0%이내의 오차를 나타내었고, 산소-아세틸렌 불꽃 납착법에서는 5.0, 10.0 mm에서는 시편금속의 구성성분이 10.0%이내의 오차를 나타내었으나, 납착 부위에서는 Ni만이 검출되어 적외선 용접법과는 차이를 나타내었다. 이와 같은 분석결과를 살펴 볼 때 적외선 용접을 시행한 시편의 구성 성분이 모금속의 성분과 유사한 것을 알 수 있었다. 결론: 이상의 결과로 산소-아세틸렌 불꽃 납착법보다 적외선 용접법을 이용할 때, 금속의 결함 및 성분의 변화가 적어서 좀 더 우수한 금속 보철물의 제작이 가능할 것으로 사료된다. PURPOSE. The purpose of this study was to compare Ni-Cr alloy property of gas-oxygen torch soldering and infrared welding using optical microscope and Electron Probe Micro Analyzer (EPMA). MATERIALS AND METHODS. Ni-Cr alloys were casted for specimens. Specimens had 3.0 mm diameter, 30.0 mm length and were divided into two groups. Each group had 4 specimens. One group was for gas-oxygen torch soldering and the other was infrared welding. Specimens were cut with low-speed disc and soldered each other with gas-oxygen torch and infrared machine. After soldering and polishing, specimens were observed at 3 points (soldering point, 5 mm distance point, 10 mm distance point) with optical microscope and analyzed 3 points (soldering point, 5 mm distance point, 10 mm distance point with EPMA. RESULTS. The results of this study were as follows: 1. The observation of gas-oxygen torch soldering at 10 mm distance point under the optical microscope was not founded any specific surface properties, but some crack lines were observed at 5 mm distance and soldering point. 2. There were no crack lines were founded at the observation of infrared welding at 10 mm distance and 5 mm distance points under the optical microscope. However, at the 5 mm distance, the surface was not smooth enough compared with at 10 mm distance point. Some crack lines were observed at the welding point as well. 3. In the EPMA analysis of the gas-oxygen torch soldering, the component of Ni was increased by 4.5%, Cr was increased by 7.5% than that of the Ni-Cr alloy at the 10.0 mm distance. At the 5 mm distance, the component of Ni was decreased by 6.1%, Mo was increased by 9.0% than that of the Ni-Cr alloy but Cr was equally shown at the 5.0 mm distance. Only Ni was shown at the soldering point. 4. In the EPMA analysis of the infrared welding, the component of Ni was increased by 9.1%, Cr was increased by 0.4% than that of the Ni-Cr alloy but Al was equal at the 10.0 mm distance. At the 5 mm distance, the component of Ni was increased by 4.7%, Cr was increased by 4.7% and Al was increased by 0.1% than that of the Ni-Cr alloy. At the welding point, the component of Ni was increased by 8.8%, Cr was increased by 8.2% than that of the Ni-Cr alloy. CONCLUSION.From these results, at the 5 mm distance from the soldering point, the surface of the infrared welding was more smoother than that of the gas-oxygen torch soldering. On the EPMA analysis, the component of the specimens with infrared welding was more similar than that of the gas-oxygen torch soldering compared with the component of the Ni-Cr alloy.

Quinlolone 유도체 국소도포에 의한 좌창치료의 임상적 연구

권철욱,노영석,김재홍,조소연,강형철,함정희 大韓臨床藥理學會 1994 臨床藥理學會誌 Vol.2 No.2

생태중심의 윤리 : 들뢰즈와 가타리의 유목적 사유 Deleuze and Guattari's Thought of the Nomadic

정형철 부산 외국어 대학교 2003 外大論叢 Vol.27 No.-

Deleuze and Guattari's thought of the nomadic defies oppressive settlement, hierachical organization, and fixed identity ; it resists socially coded modes of existence and thought. Their nomadism is directed toward liberation from the dogmatic images of thought. Their namadic mode of thought, which is based on their affirmation of difference, becoming, transformation, continuous flux, and primordial forces of the unconscious, finds new possibilities of life. It promotes non-fascist and anti-conformist modes of existence. In this sense, Deleuze and Guattari's nomadology might be discussed in terms of the ethics of the ecocentric, which is opposed to the thoughts of antropocentric, biocentric, and technocentric. Deleuze and Guattari's nomadology as well as their schizoanalysis and rhizomatics can be examined in connection with such environmental theories as deep ecology and ecofeminism. As the ecocentric mode of existence enhances an experiment in becoming and creativity, the concept of the nomadity itself resists the technocentric State apparatus that restricts the productive and creative desire. In Deleuze and Guattari's terms, the ecocentric mode of existence can be compared to the nomad war machine, which is a strategy to release the unrestrained flow of life. I am convinced that Deleuze and Guattari's thought of the nomadic might be applied to the development of new images of thought, the actualization of the politics of creativity, an understanding of the mode of postmodern desire, and the critique of the negative aspects of the modernity project. My further study will be focused on Deleuze and Guattari's nomadism and Eastern images of thought from a comparative perspective.

C형 간염의 병리조직학적 고찰

김형준,김재규,김미경,박중원,유병철,박실무 중앙대학교 의과대학 의과학연구소 1997 中央醫大誌 Vol.22 No.2

After the discovery of hepatitis C virus, several reports of histologic charcteristics of hepatitis C have been published. The aim of this study is to evaluate histopathologic features of hepatitis C for diagnostic significance. Needle biopsy specimens obtanied from the liver of 14 patients with hepatitis C were evaluated for the diagnostic significance. All patients had not any evidence of hepatitis B, and autoimmune and alcoholic liver diseases. The specimens were histologically evaluted based on previously reported features of hepatitis C such as bile duct damage, lymphocytes infiltration, steatosis and so on. According to the mode of transmission, sporadic infections were 12 cases, posttransfusion hepatitis and Ⅵ drug abuser was 1 case. The commonst finding was sinusoidal inflammatory cell activation, especially lymphocyte (86%). And lymphoid follicles or lymphocytes aggregates (65%), steatatosis (65%) were found. According to the activity of hepatitis, significant difference of pathologic features could not be proposed, but most histologic features were showned in CAH. In conclusion, all the histologic characteristics of hepatitis C such as sinusoidal cell activation, lymphoid aggregates, steatosis were observed in this study. But the further study of comparative histologic evaluation between hepatitis C and other hepatitis is needed. And also, comparative study with larger subjects for specific histopathologic findings according to the activity of hepatitis and epidemiologic cause in needed.

한의과대학 부속 한방병원 한방응급실 내원환자에 대한 임상적 분석

소형진,류재환,김영철,이범준 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2007 東西醫學硏究所 論文集 Vol.2007 No.-

Objectives : By recording basic data of patients visiting the emergency room of the oriental medicine center, we can understand their characteristics and gain better insight about them. Methods : We performed a retrospective study of 2,674 patients who visited the emergency room of Kyunghee Oriental Medical Center, from June 1, 2006 to May 31, 2007. Results : 1. Of 2,674 total patients, the male to female ratio was 0.94:1 and the 6th decade of life was the peak age group. 2. The majorit of patients visited our emergency room between 06:00 and 24:00(midnight). 3. Most patients visited on a Saturday or Sunday. 4. By monthly distribution, the patients incrcased slightly during June, July, August and October. 5. The majority of patients visited the emergency room within 24 hours of onset. 6. The patients were categorized as follows : neurological diseases 71.15%, musculoskeletal diseases 16.02%, internal medical discase 9.04% psychiatric and related disease 3.79%. 7. The average transit time waS about 1 hour 30 minutes. 8. Admission rate was 48% and the rate of admission to the intensive care unit (ICU) was 5% of total visiting patients. Conclusion : Assuming that this research will continue adding patien's data continuously, this work will help us to understand the features of patients who visiting the emergency room of the oriental medical center.

죽음 준비교육이 일 노인복지관 노인들의 죽음불안, 태도 및 생활만족도에 미치는 영향

김형철,최길순,정영 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.3

Objectives: The purpose of this study was to find out the level of death-anxiety, death-attitude and life-satisfaction of elderly's before and after offering a education program about how to die. Method: The subjects were sampled from the members of the Elderly Welfare Center in Gwangju Park. Total number was 148, 74 for the control group and 74 for the experimental group. The study was carried out after a non-equivalent pretest-posttest design. Data were collected from July 7th to August 23, 2004. The How-to-Die education was applied only to the experimental group for 50 minutes weekly, for 8 weeks. Results: 1) The fear of deathCt=4.631, p=.000) , avoidance react to death(t=1.987, p=.048) were significantly decreased in the experimental group. 2) The time and way of deathCt=3.101, p=.002), handling a dead bodyCt=-3.583, p=.000) were significantly increased in the experimental group. 3) The extent of life-satisfaction of the experimental group was significantly increased after the education(t=2.306, p=0.023). Conclusion: From the above results, the How-to-Die education for the elderly is an effective nursing intervention to decrease the level of death-anxiety, increase the level of death-attitude and life satisfaction.

해외 독립운동가들의 활동에 관한 연구 : 이승만, 김구, 김두봉(무정), 김일성 중심으로 regarding Seung-man, Lee, Ku, Kim, Doo-bong, Kim, Il-seung, Kim

신형철 경성대학교 2000 論文集 Vol.21 No.1

There were lot of limitations for national independent movements withen korea under the control of Japanes colony. Those limitations made many national independents go abroad, especially to China and USA. Therefore the center of by virtue if USA and USSR, many independents abroad returned to korea. Among them, Il-seung, Kim, Doo-bong, Kim, Chung, Moo, Guy, Her who were commonists returned to northern area of korea, and Seung-man, Lee. Giu-sik, Ik-hee, Shin etc. to southern area of Korea. Of course, a few national independents whthen korea continued to resist japanese colonial government, even though less active and considetable than abroad. Among those who resisted withen korea, there Jin-woo, Song, Deok-soo, Jang, Heon-young, Park, and Youn-heung, Yeo. And so, there formed three political groups, and each groups sought to get a hegemony over korea. these struggles resulted to the division of korea into two koreas. Il-seung, Kim who was a machiavellian partisan leader supported by USSR become a North Korea ruler, and Seung-man, Lee who returned from USA was elected as president of South Korea.

폴리아미드/폴리스티렌 블렌드의 결정화 거동에 대한 상용화의 영향

홍인철,김형일 忠南大學校 産業技術硏究所 1998 산업기술연구논문집 Vol.13 No.1

폴리아미드-6(PA), 스틸렌-무수말레인산 공중합체(SMA), 폴리스텔린(PS)를 포함하는 일련의 블렌드계에서 상용화가 분산상인 결정성 고분자 PA의 결정화 거동에 미치는 영향을 조사하였다. PA의 결정화 거동은 PA의 말단 아민기와 SMA의 산무수물기간의 축합반응을 통한 상용화 정도에 따라 크게 영향을 받았다. 블렌드에서 SMA의 함량이 증가할수록 분산상 PA의 결정화 진행이 지연되었다. 이는 계면에서 PA에 연계된 SMA분자의 운동성으로 인하여 PA의 정상적인 결정화 온도에서 PA분자의 결정격자위치로 이동하는데 방해를 받았기 때문이었다. A series of blends containing polyamide-6(PA), styrene-maleic anhydride copolymer(SMA) and polystyrene(PS) have been prepared to study the effect of compatibilization on the crystallization behavior of the dispersed semicrystalline component PA. The crystallization behavior of PA depended largely on the extent of compatibilization via the condensation reaction between the terminal amine group of PA and anhydride group of SMA. As the content of SMA was increased, the crystallization of the dispersed PA was retarded. It was because the reduces mobility of SMA which was linked to PA at the interface prevented the PA molecule from moving into a crystal lattice position at the normal crystallization temperature.