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김재형,함덕상,고복현,김대광 동국대학교 경주대학 1993 東國論集 Vol.12 No.-
Uterine cervical cancer is the most common cancer of woman in Korea. To understand which oncogenes are involved in squamous cell carcinomas of the uterine cervix, author examined nine human tissues of squamous cell carcinomas of the uterine cervix using Southern blotting techniques for five known oncogenes (H-ras, v-mos, erbB2, c-myc, K-ras). One of the nine tumors demonstrated a rearrangement of the H-ras oncogene. And amplification of v-mos was found in three tumors. The other oncogenes(erbB2, c-myc and K-ras) were the same pattern with the control. It is presumed that rearrangement of H-ras and amplifications of v-mos may be concerned to oncogenesis of squamous cell carcinomas of uterine cervix.
지구성운동 중 탄수화물 투여가 대사작용과 운동수행능력에 미치는 영향
박형대,윤영복 조선대학교 스포츠과학연구소 1998 스포츠科學硏究 Vol.9 No.-
To determine whether single carbohydrate administration, before the point of fatigue during prolonged exercise, could restore and maintain plasma glucose availability, seven trained cyclists were participated as subjects in the present study. Subjects performed exercise tests on a monark ergometer to fatigue at 70% of VO_2max on two occasions. After 140 min of exercise, the subjects were administrated either placebo of glucose polymer. Prolonged exercise led to a decline in plasma glucose as exercise was continued. Plasma glucose decreased further at fatigue following placebo administration but increased and was then maintained following carbohydrate administration. Respiratory exchange ratio fell gradually during the placebo administration during exercise. After carbohydrate administration, respiratory exchange ratio increased again as plasma glucose rose. Exercise time to fatigue was 23% longer during the carbohydrate administration trial. Plasma insulin did not increase significantly following carbohydrate administration. This indicates that single carbohydrate administration at 140 min of exercise at 70% of VO_2max can supply sufficient carbohydrate to restore euglycemia, increase carbohydrate oxidation and delay fatigue.
당밀의 첨가가 갈근탕박 사일리지의 품질과 산양의 기호성에 미치는 영향
김성복,문계봉,이봉덕,오홍록,배형철,이수기 충남대학교 농업과학연구소 2006 농업과학연구 Vol.33 No.1
Two experiments were conducted to investigate the effects of molasses supplementation to silage materials in ensiling Galgeuntang (herbal medicine) meal on the quality of silage, and its palatability in Korean native goats. In experiment Ⅰ, molasses was added at the levels of 0, 0.5, and 1.0% to Galgeuntang meal with three replicates per treatment. In experiment Ⅱ, three 1.5-yr-old Korean native goats were used to measure palatability. In experiment Ⅰ, lactic acid contents in molasses treatments were significantly(p<0.05) higher, and pH and butyric acid contents were lower than those of non-molasses treatment. In addition, molasses treatment increased total microbial cell counts in MRS medium for lactobacillus, but decreased total microbial cell counts in PDA medium for fungi. Molasses supplementation to silage materials increased in vitro dry matter disappearance. Molasses supplementation tended to increase silage intake in Korean native goat (experiment Ⅱ), but the difference was not significant(p>0.05). It is concluded that molasses supplementation to silage materials in ensiling herbal medicine meal could improve its preservability and palatability, the higher the better.
민태형,조복현 大田産業大學校 2001 한밭대학교 논문집 Vol.18 No.-
The economy of Daejon-Chungnam region is expected to grow and develop rapidly, due to the active enterprise start-up concentrated in Daeduck Science Complex at Daejon and the establishment of heavy-chemical industrial park along the west-sea belt in Chungnam. Based on them, Daejon and Chungnam region governments have planned the long-term economic development strategies each other. Daejon government has made the plan to foster the hi-tech industry, the knowledge-information industry and the circulation center of commodity. Chungnam set up the plan to bring up the four comparative advantage industries and the five knowledge-based industries. We will assess these plans of both region governments based on the specific characters of both region economies. We suggest that both governments should make the plan to cooperate and complement, not to compete and overlap each other. And both governments should plan the strategies that can booster not only hi-tech industry, but also existing low-tech industry so that maintain high employment and equivalent development.
장상피화생과 Helicobactor pylori와의 상관 관계에 관한 연구
이복희,김대수,이현숙,진영주,윤세진,송형근,성노현,정현용,이동호 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2
In 1965 Lauren divided advanced gastric carcinoma into two main types-namely, "intestinal" and "diffuse" type carcinoma, which differ not only morphologically but also in their clinical and epidemiological characteristics. Moreover, a different histogenetic process has been postulated by many authors that intestinal type gastric carcinoma might arise from areas with intestinal metaplasia. Since Warren and Marshall reported the presence of Helicobacter pylori in the stomach in 1983, strong evidence has been obtained that there is a close relationship between Helicobacter pylori and chronic gastritis, atrophic gastritis, intestinal metaplasia, and intestinal type gastric carcinoma. To study the relationship between intestinal metaplasia and Helicobacter pylori infection, we performed gastroscopic biopsies and CLO tests taken from patients with epigastric pain. Only 87 patients with macroscopically suspected antral gastritis were included. The prevalence of intestinal metaplasia in gastric antral biopsies increased from 33.3% in the age group<30 years to 63.6% in the age group 60 years. When all patients were divided into two age groups-namely, (i)<50 years(n=41) and (ii)≥ 50 years(n-=46), intestinal metaplasia was found significantly more often in patients ≥ 50 years. ((i) 39.2%, (ii) 54.3%, p<0.0001). The prevalence of Helicobacter pylori in gastric antral biopsies decreased from 66.7% in the age group<30 years to 62.5%, in the age group in the age group 50 to 59 years. When all patients were divided into the same two age groups-namely(i)<50 years and (ii)≥50 years, the prevalence of Helicobacter pylori did not differ between two groups in a statistically significant way. The mean age of intestinal metaplasia positive patients who were also Helicobacter pylori positive was 48±11.0(mean±S.D.)years, whereas the mean age of intestinal metaplasia positive patients who were Helicobacter pylori negative was 52±9.7(mean±S.D.)years. In conclusion. although our data do not prove a causal relationship between Helicobacter pylori infection and the histogenesis of intestinal metaplasia, we suggest that Helicobacter pylori plays an important role in the development of intestinal metaplasia in the gastric mucosa. Whether Helicobacter pylori has to be present at all times during this process or is only necessary as a 'trigger', needs further research.