상악동 중격 : 발생빈도, 형태 및 해부학적 중요성

장현석,임재석,권종진 고려대학교 임프란트 연구소 2000 임프란트연구지 Vol.2 No.1

It is essential to identify and localize the maxillary sinus septa in maxillary sinus lift procedure to prevent tearing of sinus mucosa. The variations and frequency of bony septa in the maxillary sinuses were studied prospectively by means of computed tomography. PATIENTS AND METHODS: The presence and morphology of the septa in the maxillary sinuses were studied in 80 non-selected adults. RESULTS:CT examinations of 160 maxillary sinuses were done. The septo were observed in patients.

관상동맥질환 환자에서 스텐트 시술 후 재협착에 관한 연구

강진환,권영주,박상호,한대희,이상철,김명구,변정득,최병조,심규혁,온영근,현민수,김성구 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background and aims : In the coronary artery disease, a rate of restenosis was much decreased by placement of coronary stent than when percutaneous transluminal coronary angioplasty has been applied, but there are still important clinical problems of restenosis. There has been many progressive studies about various factors contributed to this restenosis. So, we studied a relation between restenosis after placement of coronary stent in the coronary artery disease and many clinical factors, characteristics of stenotic lesion and procedural factors, and also assessed the restenosis rate of various coronary stents. Methods : Total 58 lesions(46 cases of patients ; man 30, woman 16) were evaluated, which has been performed a follow-up coronary angiography after 6 months (mean 188 days) since coronary stent had been placed. Various stents were implanted and assessed a relation between restenosis and many factors. Results : Of 58 lesions were target stenotic studies, there were 22 of restenotic lesions(37.9%), and the restenosis rate wes statistically significant difference in the relation with diabetes mellitus(p<0.05), group of acute myocardial infarction(p<0.05) among clinical diagnosis of ischemic heart disease(stable angina, unstable angina and acute myocardial infarction) in clinical factors and with high dilation pressure of stent(p<0.05) in procedural factors. When the rate of restenosis was evaluated among implanted stents, it was lowest in the Multilink^(®) stent and highest in the Nir Royal^(®) stent(60%). Conclusion : In this study of restenosis and various factors after placement of stents in the coronary artety disease, factors such as diabetes mellitus, group of acute myocardial infarction and a dilation pressure of stent were significant related with restenosis and the restenosis rate of Multilink^(®) stent was lowest and the highest restenosis rate was of Nir Royal^(®) stent.

능동 시청각 시스템을 위한 MPSoC 구현

김영진,이현수 경희-다반 ASIC 설계교육센터 2007 경희-다반 ASIC센터 논문집 Vol.8 No.-

능동 시칭각 시스템은 시각과 청각에 대한 정보를 수집하는 과정에서 보다 더 좋은 정보를 얻기 위해 능동적으로 반응 할 수 있는 시스템을 말한다. 능동 시청각 시스템은 인식괴 행동을 수행 할 수 있는 모든 분야에서 필요한 기능이다. 능동 시각 시스템과 능동 청각 시스템은 독립적으로 구현하는 경우가 많으나, 시각 시스템은 이미지 센서에 의존함으로 이미지 센서 밖에서 얼어나는 일에는 는동적으로 반응 할 수 없으며, 센서의 모든 영역에 대한 연산 처리량이 많다는 단점을 갖고 있다. 또한 청각 시스템은 능동적으로 반응하도록 시스템을 구연하면, 모터의 잡음이나 주위 환경에 의해서 정확한 위치를 판단하기가 어려운 단점을 갖고 있다. 그러므로, 두 시스템의 단점을 보완하기 위해서 통합시스템을 구현할 필요성을 갖고 있다. 또한 시각과 청각 정보는 동시에 발생할 경우가 많음으로 두가지 시스템을 병렬로 구현할 필요성을 가지고 있다. 따라서, 본 논문에서는 능동 시청각 시스템을 MPSoC(MultiProcessor System On Chip)로 구현함으보써 능동 시각으로서 제한된 시야의 한계를 극복하고, 시선의 집중을 통해 연산량을 줄이든데 목적이 있다. 또한 각 프로세시가 병렬로 동작함으로써 동시에 발생하는 두가지 정보를 병렬로 처리할 수 있도록 구현하였다.

Redundant Binary Booth Encoding을 이용한 FIR 필터 코어의 설계

장영진,이현수 경희-다반 ASIC 설계교육센터 2000 경희-다반 ASIC센터 논문집 Vol.1 No.-

In this paper, we propose the architecture of a fast programmable FIR filter core that can be used in digital signal processing demanding high-speed and high-order digital filtering. To reduce the complexity of multiplication and addition, we adopt a redundant binary representation. It can perform addition in a constant time independent on the word length of multiplicand. Since FIR computing needs addition proportion to the size of tap, fast addition and reduction method plays a key role in implementing a fast FIR filter. The proposed method results more than 100M/s. And it has a programmability and scalability for use a variety of signal processing.

골격성 제3급 부정교합환자의 하악지 시상분할 골절단술후 하안면 폭경 및 고경의 변화에 대한 두부계측 방사선학적 연구

장현석,임재석,권종진,이부규,손형민 대한악안면성형재건외과학회 2000 Maxillofacial Plastic Reconstructive Surgery Vol.22 No.3

Purpose : The purpose of this study was to analyze the lower third facial changes in frontal view after mandibular setback surgery. Materials and Methods : In this study, fifteen subjects(6 males and 9 females) with class III dental and skeletal malocclusions who were treated with BSSRO(Bilateral Sagittal Split Ramus Ostetomy) were used. Frontal cephalometric radiographs were taken preoperatively and more than 6 months postoperatively, and hard tissue(H2-Hl) and soft tissue changes (S2-S1) were measured on vertical and horizontal reference lines. In 15 cases, changes which developed more than 6 months after surgery were studied. Results : The results were as follows. 1.In the facial height, hard tissue decreased(2.46±2.76mm) with statistical significance(P<0.01), and soft tissue also decreased(1.64±3.66mm). As a result, the facial height generally becomes shorter after sagittal split ramus osteotomy. 2.In the mandibular width, hard tissue decreased(2.08±3.59mm) with statistical sgnificance(P<0.05), but soft tissue increased (2.14±5.73mm) without statistically significant difference (P>0.05) postoperatively. 3.In the facial index, hard tissue decreased(0.23±2.21%), but soft tissue increased(2.41±3.46%) with statistical significance. Conclusion : One of the main purpose of orthognathic surgery is to achieve facial esthetics and harmony. In order to fullfill this purpose, it is important to carry out a precise presurgical treatment planning by estimating the changes of frontal profile after surgery.

RE-09 : High mobility group box-1 and Toll like receptor 4 in Endometriosis: Mediating NF-kB pathway

( Bo Hyon1 ),( Yun Ji Jung ),( Seung Joo Chon ),( Yoo Jin Lee ),( E Jung Han ),( Sihyun Cho ),( Young Sik Choi ),( Byung Seok Lee ),( Seok Kyo Seo ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: The aim of the study was to examine the sterile, chronic inflammatory status in endometriosis by detecting High mobility group box-1 (HMGB-1), and HMGB-1 signaling through toll like receptor (TLR) 4 in endometrial stromal cell, which activates NF-kB pathway that might play a pathogenic role in endometriosis. 방법: Total 69 patients who had undergone hysterectomy from March, 2012 to March, 2014 were included: 39 patients who had endometriosis as case group, 30 participants without endometriosis as the control. Expression of HMGB-1 in endometrium was examined by immunohistochemistry. From endometriosis patient, eutopic endometrium was obtained and used to culture in vitro. To confirm the association of HMGB-1 and TLR4 in NF-kB pathway, the cultured human endometrial stromal cells (HESCs) were treated with recombinant HMGB-1 (15 ng/mL) for 0, 12, 24, 48 hrs. TLR4 antagonist (LPS-RS) was added after rHMGB-1 treatment to HESCs to see the change of proliferation after inhibiting TLR4. CCK8 proliferation assay kit. Real-time PCR and western blotting were used to examine the proliferation, quantification of the mRNA and protein. Specific inhibitor of NF-κB signaling pathway (TPCA-1) was used to explore the role of NF-κB signaling pathway in HESCs proliferation. 결과: HMGB-1 expression was significantly higher in glandular epithelial and stromal cells of endometriosis group compared to the controls. rHMGB-1 significantly enhanced cell proliferation in HESCs and increased TLR4 expression by dose dependent fashion. Inhibiting TLR4 by LPS-RS, cell proliferation in HESCs and expression of TLR4 were significantly decreased comparing to the controls. After blocking NF-kB pathway with TPCA-1, cell proliferation in HESCs was significantly decreased by dose dependent fashion. 결론: This study showed that HMGB-1 may play an important role through TLR4 and NF-kB pathway, in inflammatory cascade of pathogenesis in endometriosis.

여성복식에 표현된 가슴의 패션 정체성 : 19세기 한국 · 프랑스를 중심으로 Focusing on Korea and France in the 19th Century

오유진,최현숙 동덕여자대학교 디자인연구소 2004 디자인포럼21 Vol.7 No.-

본 연구는 패션 정체성 이론에 근거하여 패션의 정체성을 보다 확실히 이해하고, 나아가 이를 디자인 발상의 연구 기초 자료로 활용할 수 있음을 증명하고자 하는데 그 목적이 있다. 패션 정체성을 설명하는 구체적인 사례 제시를 위해 19세기로 연구 시대 범위를 한정했다. 또한 보다 구체적인 연구를 위해 연구대상을 한국과 프랑스로 선정했다. 이러한 연구 범위 안에서 문헌 및 실증 자료들을 통해 패션과 문화의 상관성을 바탕으로 한국과 프랑스의 패션 정체성을 비교 연구한다. 특히, 여성의 가슴에 관한 두 나라의 인식의 차이가 어떻게 패션 디자인에 다르게 표현되었는지 파악하고 이를 바탕으로 보다 발전적인 디자인 발상을 통한 패션계의 발전을 도모하는데 연구의 의의를 두었다. 한국과 프랑스의 가슴의 패션 정체성을 비교해본 결과, 양국 모두 모성성, 관능성, 패션성이 공존했다. 단 이러한 가슴의 패션 정체성의 표현 방법에 있어서 차이를 보였다. 19C 한국과 프랑스 여성복식에 표현된 가슴의 패션 정체성은 '은폐/노출'이라는 양면성을 갖고 복식안에서 보다 구체적으로 표현된다. 전체적으로 살펴볼 때, 양국 모두 가슴의 각 정체성 성격 마다 위에서 언급한 세 가지 정체성 성향이 모두 나타났다. 그리고 '은폐/노출'이라는 양면적 성향에 있어서는 관능성에 있어서 대조적인 차이를 보이고 모성성에 있어서는 동일한 성향을 띠고 있다. 또한 패션성에 있어서는 프랑스는 은폐와 노출이 모두 나타난데 반해 한국은 은폐적 성향을 띠고 있다. 이것은 양국간의 가슴에 대한 인식의 차이에서 비롯된 것이라 할 수 있는데 이러한 인식의 차이는 곧 문화적 차이를 의미하는 것이다. 연구의 결과 패션과 문화사이의 밀접한 상호 관련성을 재확인할 수 있었으며, 특히 여성 패션에서 가슴의 패션 정체성과 복식문화의 상관성을 찾아 볼 수 있었다. 각기 다른 문화권이나 시대는 각각 고유한 패션 정체성을 갖는데, 이러한 상호 독립적이면서 상이한 패션의 상대성에 대한 존중은 넓은 시각에서 패션을 이해할 수 있게 하며 새로운 패션을 창출하는 원동력이 된다. The women's dress style in the 19th century in Korea and France is influenced by diffrent socio-cultural trend. The two fashion trends in Korea and France build diffrent fashion identity based on their cultural influences. It causes diffrent perceptions and expressions of the dress styles to women's breasts in the oriental and western society until now. The purpose of this study was to understand the fashion identity more clearly based on the theorem of the fashion identity, also to prove the availability of using it as the groundwork for studying the design concept. This thesis focused on the 19th century to suggest a concrete example to explain the fashion identity. In addition, Korea and France are selected for the same reason. Korea and France fashion identity is compared each other in this study through various literature and actual proof based on the corelationship between the fashion and the culture. Especially, the diffrence of cognition of the breasts between the two countries is studied in order to investigate how it is expressed in the fashion design and to search the way of development of fashion world is seek for through more developing design concept on the basis of it. As the result of the fashion identity study about the breasts in Korea and France, the nature of motherhood, sexuality, and fashion was shown for two countries. Yet, the way the breasts fashion identity was expressed was different in two countries. This differentiation comes from the recognition of the breasts in the two countries, which means different culture of them. In other words, fashion and culture have a close relationship, and the corelationship between the breasts fashion identity and dress culture could be expected. In addition, different culture and time period different characteristics of fashion identity. Those are independent and relative to each other at the same time. This is helpful in understanding fashion the role and meaning of it through the comparison analysis of the breasts fashion identity expressed in women's dress style in the 19th century in Korea and France. Also, it suggested the foregoing way of the future fashion identity of the present dress design through the comparison of old dress style. The fashion identity plays an important role in taking the new fashion and approving a culture relativity in accordance to the global trend of the present fashion. The fashion identity forms the initial factor of the conception of fashion design. Pursuing one's own fashion with identity would make that fashion even more active and confident.

강원도 삼척지역의 스멕타이트질 점토의 산상 및 특성

황진연,박성완,이상현,최수용 부산대학교 기초과학연구소 1995 부산대학교 기초과학연구소 연구논문집 Vol.15 No.-

The smectite-rich clays were found locally in Paleozoic calcareous sedimentary rocks in the Samcheok area. Their occurrences were investigated in detail, and the physico-chemical properties of the clays were also determined by X-ray diffraction, chemical analysis, thermal analysis and cation exchanging experiment. The smectitie clays occur as the fissure filling dyke developed in calcareous semimentary rock and as alteration products of instrusive rhyolite. Most of clays occur at the contact between the sedimentary rock and the rhyolite, and the alteration zone was observed only in rhyolite body close to the contact. Judging from their occurrences, it is believed that the smectite-rich clays in this area were formed by the hydrothemal alteration. The smectite clays from the area are mainly composed of Ca-montmorillinite, and associated with small quantities of quartz, opal-CT and feldspar. The montmorillinites from this area lower in Fe content, and higher in exchangeable Ca ion, compared to those of bentonite from the Yangnam-Yeongil area.

家兎에 있어서 頭蓋內壓亢進이 Picrotoxin 痙攣에 미치는 영향

姜珍祥,鄭光現,丁相鍵,李順揆 大韓神經精神醫學會 1973 신경정신의학 Vol.12 No.1

After intravenous administration of picrotoxin, 4 steps of responses were observed, i. e. a) tremor and disturbance of righting reflex b) clonic convulsion c) tetanic convulsion and d) death. Picrotoxin (1㎎/㎏) elicited above responses 14.2 (a), 32.6 (b) and 38.8 (c) minutes after intravenous administration, exhibiting shortening of the duration with Increased doses. Jncreased intracranial pressure by intraventricular administration of saline or extradural balloon method facilitated picrotoxin convulsion. Phenobarbital and dilantin suppressed picrotoxin convulsion and facilitating effect of intracranial pressure on picrotoxin convulsion. Possible mechanism of the effect of increased intracranial pressure on picrotoxin convulsion was discussed.

가토 두개부 골결손부 우골 유도 골이식재의 이식시 농축 혈소판 혈장(Platelet-Rich Plasma:PRP)의 효과에 대한 실험적 연구

장현석,권종진 고려대학교 임프란트연구소 2001 임프란트연구지 Vol.3 No.1

There are so many cases which need grafts of bone defect as the reconstruction of post-tumor resection surgery site or trauma site, surgical management of alveolar cleft and oronasal fistula, bone grafts associated with osseointegrated implants and maxillary sinus lifting procedure. Among the method of bone defect reconstruction, that which uses the fresh autogenous bone has disadvantages that it gives also another trauma on the donor site and volume is reduced after the operation and it has limit of quantity. Another method using the commercial allogenic bone and composite bone like the Hydroxyapatite and Tricalcium phosphate has disadvantages that it takes poor tissue responses and its material works only as the passive scaffold. To gain the functional and much alveolar bone, Research is being carried recently that developing and purifying the various growth factor, applying the results of research to clinical situation. The materials promoting the bone formation are Bone Morphogenetic Protein(BMP), Platelet-Derived Growth Factor(PDGF), Transforming Gruwth Factor-beta(TGF-β). It is reported that Platelet-Rich Plasma(PRP) has PDGF, TGF-β and the abilily of promoting the bone formation. In this study, I compared the defect that have been healed naturally without any bone grafts as the control site, the other defect have been augmented only with bovine bone grafts, with another defect have been augmented with bovine bone grafts and Platelet-Rich Plasma simultaneously. I wanted to see whether much better results of bone formation on using the PRP have been gained, through the method of histologic evaluation. The results was gained as follows on the light microscopic examination. 1. The defect have been augmented with bovine bone grafts and PRP simultaneously showed the higher bone density and much bone formation than that have been augmented only with bovine bone grafts, especially on the eighth week's histologic examination. 2. Comparing the histologic specimen of the defects by the time elapse, Bone grafts with PRP simultaneously had the fastest bone growth rate among the three defects above. 3. The defect that have been heated naturally without any bone grafts had much fibrous tissue and less new bone formation. It seems that using the bone graft and PRP simultaneously on the bone defect gains the better bone healing as the above results.