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      • KCI등재

        곡물별 담자균 배양물의 효소활성

        박효숙 외 한국버섯학회 2010 한국버섯학회지 Vol.8 No.3

        In this study, growth rates and enzyme activities of mushroom mycelium were investigated in each cereals. Cultivation on hulled barley resulted in slightly faster mycelial growth as compared to other substrates. Enzyme activities were measured in different periods. In result, α-amylase activity was higher in Pleurotus ostreatus and Phellinus linteus cultured cereals, whereas β-amylase activity was higher in Pleurotus ostreatus and Fomitella fraxinea cultured. Protease level did not affect kinds of cereal except Phellinus linteus. The color values lightness decrease by Basidiomycetes cultivation and redness and yellowness increased. 본 연구는 곡류별 버섯 균사체의 성장률과 효소활성을 측정하였다. 현맥 배양물이 다른 곡류와 비교했을때 균사체 성장 속도가 빨랐다. 효소 활성은 기간별로 측정하였으며 그 결과, α -amylase 효소 활성은 느타리와 상황버섯균이 우수하였으며, β -amylase활성은 느타리와 장수버섯균이 우수하였다. Protease활성은 상황버섯균을 제외하고는 곡물에 관계없이 비교적 고른 생산을 보였다. 담자균 배양에 의해서 명도는 감소하고 적색도와 황색도가 증가하였다.

      • MLS를 이용한 접근 유도에 관한 연구

        李貞碩,張殷永,金元厚,方孝昌 한국항공대학교 1991 論文集 Vol.29 No.-

        MLS(Microwave Landing System)는 어떤 활주로 상황에서도 기종에 관계없이 계기착륙이 필요한 항법정보를 정확하고 신롸성있는 상태에서 넓은 운용범위를 갖게되는 시스템으로서 ILS보다 장비기술 및 운용면에서 우수한 것으로 입증되었으며, 공항의 장애물과 악지형의 영향에 따라 유도특성이 방해받더라도 시스템의 가용성에는 제한이 없도록한 특징이 있다. 본 논문에서는 기존의 ISL의 접근절차로서는 불가능했던 비표준 지형과 평행 활주로에서 MSL를 이용한 접근 유도시 활주로 중심선에 대한 접근 오차 한계를 계산하고 기준 활주로와 평행 활주로 각각에 대한 접근유도시 거리오차를 산출하여 MSL를 이용한 정밀 접근유도 상태를 검토하였다. 그 결과 MSL는 비표준 지형 및 평행 활주로에서도 5NM이내의 거리에서는 접근오차가 0.1%(0.16NM)이내를 유지하여 ICAO 기준을 만족함으로써 규정상의 접근유도가 가능함을 알수 있었다. The MLS was followed by definition of a signal-in-space having the accuracy, reliability and coverage to aeronautics needs for all type of aircraft at all runway suitable for terminal instrument procedures. MLS has been demonstrated to be superior to ILS from both technical and operational capabilities. Even at runway where ground terrain and airport obstacles prevent standard split-site installations, the availability of MLS will not be limited. In this thesis, the range error and limitted error bound of a computed centerline approach is derived and identified in order to solve the problems of percision approach guidence at non-standard sitin gand parallel runway. As the result, it is known that the MLS is able to approach guidence with 0.1%(0.16NM) limited range error at non-standard siting and parallel runway within 5NM.

      • 공기 싸이클론 분리 장치의 분체 분리 효율

        姜錫浩,朴永孝,金珠浩,朱星浩 嶺南大學校 工業技術硏究所 1985 연구보고 Vol.13 No.1

        The collection efficiency of the Lapple's standard-type cyclone separator was determined in order to investigate the effects of the particle size of the dust samples, the dust loading, and the air inlet velocity to the cyclone under the ambient conditions. The experimental conditions are in the following ranges; the air inlet velocity; 5 to 14.7 m/s, the particle sizes of the mono-dispersed system; 14 to 280 ㎛, the dust loading; 17.8 to 58.6 g/㎥, respectively. The collection efficiencies determined were compared with those predicted by the semi-empirical equations proposed earlier by Strauss (³) and by Licht et al, (⁴) and those are shown to be increased, as the particle size of the sample dusts and the air inlet velocity increase, respectively. However, the effect of the dust loading in the air could not be recognized, but slightly increased. For the poly-dispersed particulate samples, having a wide particle size distribution, the grade or separation efficiency curve was experimentally determined to specify more exactly the cyclone separation performance, and the result was discussed with the statistical analysis previously worked by Herrmann.(??)

      • 조선시대 목공예의 금속장식에 관한 연구 : 경첩장식을 중심으로

        서효석 진주여자전문대학 1996 論文集 Vol.19 No.-

        Man has produced various of technical products to more and enrich his life and make it convenient. The technical culture has been kept developing up to today, with the infinite efforts, for the purpose of meeting these natural wished of mankind. The treces which the race has trod, whichever races their countries consist of, have the traditions descending from deep roots through customs and beliefs in themselves. In the heart of these traditions, there was a technical culture of wooden technical arts which was glorious in the Chosun Dynasty's era. But as the period elapsed Dynasties changed their hands it must in turn be great pities that in accordance to the changes of the period the glorious cultural heritages should be extinguished and destroyed. On theis account, I would seek to search for 'the Korean characteristic', the flaver and beauty of Korea so that we might rediscover ours in the disappearing traditions. This thesis shows that not only the kind and use of the wooden technical arts in the Chosun Dynasty's era but especially the kind of desighs, the function and name of the metal-ornament got analysed, and that in carefully studying and examining the the designs, forms and function of hinges I would appreciate the excellent tradition and wisdom of our nation borne in the hinges. As the metal-ornament bears the human in erest of a nation most naturally and plainly, as the wooden technical arts do well represent peculiar characteristics thickening the local colors, the purpose of this thesis on the metal-ornament is to establish the function and aesthestics of the metal-ornament attached in the wooden technical arts, to reanalyse our tradition on the basis of modem views and to present the modem metal-ornament, especially the direction of hinge-designs. Therefore, the result of these researches is expected to be the available data presenting the direction of the designs and the imporvements of the modern metal-ornament.

      • 졸·겔法에 의한 TiN 薄膜 製造에 關한 硏究

        宣孝任,姜泰範,李奭鎬 상명대학교 논문집 1993 상명대학교논문집 Vol.31 No.-

        The polymeric sols were prepared by hydrolysis and polymerization of titanium tetraisopropoxide in diethanolamine. TiO_2 coating films prepared by dip coating of alumina substrate with polymeric sols were heated at various temperature for 7 hours in NH_3 gas. TiN thin films obtained from TiO_2 were investigated by XRD. TiO_2 coating film on alumina substrate was converted into the TiN thin film by nitridation under the flow of NH_3 gas at 1100℃ for 7 hours.

      • 그레이브스병에서 방사성 요오드 치료에 따른 갑상선 자극 호르몬 수용체 결합억제 면역글로불린(Thyrotropin Binding Inhibitory Immunoglobulin, TBII)의 변화

        조영석,권기현,이준철,나소영,이효진,홍우정,이유선,김군순,송민호,김영건,노흥규 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

        Prediction of thrapeutic response to radioiodine in Graves' disease is poorly understood. Although thyrotropin binding inhibitor immunoglobulin(TBII) level is a strong index for relapse after antithyroid drug medication, conflicting results are reported regarding its prognostic significance in Graves' disease treated with RAI. This study is dengned to evaluate possible relationship between post-treatment hypothyroidism and TBII in Graves' disease treated with RAI. Fourty two patient with Graves' disease after radioiodine treatment were studied retrospectively. The subject were divided into hypothyroid group and euthyroid or hyperthyroid group. We evaluated the association of hypothyroidism and TBII with radioiodine treatment dose. The mean age of hypothyroid group was 48±11 years and euthyroid or hyperthyroid group was 47±12 years. There was no difference in two groups. And there was no significant difference in post- treatment TBII between two groups(49.9±28.5%, 29.9±14.3%, p-value >0.05). The treatment-dose had no influence on post-treatment thyroid state. Euthyroid or hyperthyroid group was done with 13.6±6.9mCi and hypothyroid group was 17.0±10.4mCi(p-value > 0.05). TBII had no prognostic significance on long-term hypothyrodism in Graves' disease treated with radioiodine. And, treatment-dose had no influence on post-treatment thyroid state.

      • KCI등재

        정신치료 집단 Supervision 경험

        임효덕,강석헌,김승업 大韓神經精神醫學會 1990 신경정신의학 Vol.29 No.4

        The author reviewed the 32 tape recordings of successive series of psychotherapy group supervision sessions, and studied the reaction of supervisees through a questionnaire. The group supervision sessions were conducted by a psychotherapy supervisor of Kyung-pook National University Hospital from February 1988 to July 1989. Twenty-one psychiatric residents and one co-supervisor participated. Each session ran 90 minutes once every other week. A supervisee's psychotherapy case was reported and it was followed by group discussion, supervisor's interventions and summary remarks. The tape recordings were analyzed in terms of most frequent mistakes and shortcomings of psychotherapy practice. The author distributed a questionnaire to find the reactions of the participants to the supervision sessions. The results could be summarized as follows ; The frequent mistake and the lack of therapeutic ability indicated by the supervisor were therapeutic interchange without clear understanding of the patient's nuclear emotions or central dynamics, the therapist's inability for empathic understanding and the therapist's lack of genuine interest in the patient. In terms of the technical shortcomings of the resident therapists, insufficient clarifications of the important issues, the tendency to neglect the formal history taking, frequent changes of the topic by the therapists because of their own needs and anxiety, premature interpretations and closed question methods. In the answer of the questionnaire composed of 18 items, all 21 participants responded that the supervision experience was helpful in understanding theoretical as well as practical aspects of psychotherapy, but some reported that the experience was perceived as provoking undue anxiety and even hostility. The author concludes that the group psychotherapy supervision model is suitable for the resident training in psychotherapy and the competence of the supervisor is the prerequisite condition for the group supervision.

      • 돼지에서 정맥, 근육 그리고 경구 투여시의 enrofloxacin의 약물동태학

        윤효인,김무열,박승춘,조준형,박병권,이내경,노상석,장범수,신광순,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

        In order to characterize pharmacokinetic profiles according to route of a new enrofloxacin salt form (Enrotil®), it was given to 4 healthy pigs via oral (p.o.), intramuscular (i.m.) or intravenous (i.v.) administrations at a dose rate of 5 ㎎/㎏ body weight. Enrofloxacin (ENFX) in serum was detected by bioassay using E. coli BE1186 as a test organism. The biological elimination half-lives (t_1/2(β)) of ENFX were 6.76±0.99 h (i.v.), 7.16±2.30 h (i.m.) and 11.45±3.90 h (p.o.), Volume of distribution (Vd) of enrofloxacin was 2.20±0.31 L/㎏ (i.v.), 2.52±0.60 L/㎏ (i.m.) and 1.88±0.33 L/㎏ (i.m.). Mean residence time (MRT) was 8.77±1.26 h after i.v. injection and the maximal concentration time (Tmax) following p.o. and i.m. administration was 0.76±0.09 h and 0.60±0.12 h, indicating a rapid absorption from these routes. Bioavailibility (F) was calculated as 64.1% for p.o. administration and 59.71% for i.m. injections. In summary, the newly formulated enrofloxacin salt form has shown a high water solubility, rapid absorption and large tissue distribution, suggesting a potential antibacterials for oral application on a large scale in veterinary sectors.

      • KCI등재후보

        혈청 Aminotransferase치의 만성적 상승을 보이면서 HBsAg 음성인 환자의 간조직 소견 : 지방간 환자에서 체중감량에 의한 간기능 검사의 개선효과 Effect of Weight Reduction on Aminotransferase Elevation

        양석균,이영상,이효석,김정룡 대한내과학회 1992 대한내과학회지 Vol.42 No.2

        HBsAg이 음성이면서 지속적으로 고 aminotransferase 혈증을 보이는 환자들의 임상적 의의는 잘 알려져 있지 않다. 저자 등은 AST치에 관계없이 6개월 이상 ALT치의 상승을 보인 HBsAg 음성 환자들 중 기왕력상 만성적 과다음주, 상습적 약물 복용 또는 당뇨병이 있는 환자들과 이학적 소견 및 내시경 검사상 간경변증의 소견을 보인 환자들을 제외한 102명을 대상으로 첫째, 간조직 검사를 통하여 지방석 간질환과 만성 활동성 간질환의 상대빈도를 알아내고 둘째, 이들을 감별할 수 있는 비침윤적 진단 지표를 찾아내고자 임상적, 생화학적 검사를 시행하여 다음과 같은 결과를 얻었다. 1) 대상환자 102명중 지방성 간질환이 66예(64.7%), 만성 활동성 간질환이 35예(34.3%) 이었으며 1예에서는 특이한 병리학적 소견을 볼 수 없었다. 2) 상대체중이 100% 미만인 환자들의 간질환은 만성 활동성 간질환일 확률이 높았고(100%), 120% 이상인 환자들은 만성 활동성 간질환의 유뭉에 관계없이 지방성 변화를 동반할 확률이 높았다(95.3%). 3) AST치가 정상범위 내에 있거나 ALT치가 정상의 2배 이하인 환자들의 간질환은 지방성 간질환일 확률이 높았고(94.6%), AST치가 정상의 3배를 넘거나 ALT치가 정상의 5배를 넘는 경우는 만성 활동성 간질환일 확률이 높았다(87.5%). 4) Alkaline phosphatase가 증가한 경우 또는 혈소판수가 감소한 경우의 간질환이 만성 활동성 간질환일 확률은 각각 77.8%, 90.9%이었다. 5) 3㎏ 이상 체중 감량이 가능하였던 지방성 간질환 환자 29예 모두에서 ALT치의 감소를 보엿고 이 중 25예에서 ALT치가 정상범위 내로 감소하였다. 이상의 결과로 상대체중, AST, ALT, alkaline phosphatase, 혈소판수 및 체중 감량의 시도는 일부 환자에서 지방성 간질환과 만성 활동성 간질환의 감별진단에 유용하다고 생각된다. 그러나 상대체중이 100~120%이고 AST치가 정상의 1~3배이며 ALT치가 정상의 2~5배인 경우는 간조직 검사에 의해서만 감별이 가능하다고 판단되며, 이러한 겨우에 최근에 개발되어 임상적 사용이 가능한 C형 간염 바이러스 항체의 검출이 감별진단에 얼마나 유용하지에 대해서는 좀더 많은 연구가 필요하리라 생각된다. The nature of chronic aminotransferase elevations in HBsAg-negative patients has not been well known. The present study was designed to determine the relative frequencies of fatty liver disease (FLD) and chronic active liver disease (CALD) in 102 HBsAg-negative patients whose alanine aminotransferase (ALT) levels were abnormally elevated for more than 6 months regardless of aspartate aminotransferase (AST) levels. We have also evaluated clinical and laboratory investigative procedures including relative body weight (RBW) to suggest noninvasive diagnostic parameters which can be useful in discriminating FLD from CALD. Standard body weight (SBW) was calculated by the following equation: SBW(㎏)= [Height (㎝)-100] × 0.9 Those with histories of excessive alcohol consumption, drug abuse or diabetes mellitus, or with physical and endoscopic signs of liver cirrhosis were excluded. The results were summarized as follows: 1) Of all 102 cases, FLD was found in 66 cases (64.7%) and CALD in 35 cases (34.3%). In one case, there was no specific pathological finding. 2) The patients whose RBWs were below 100% were likely to have CALD (positive predictive value (PPV) = 100%). and those whose RBWs were 120% or more were apt to have fatty changes regardless of preexisting CALD (PPV=95.3%). 3) The patients whose AST levels were within normal range or whose ALT levels were below two times of upper normal limit were probable to have FLD (PPV=94.6%), while those whose AST levles were over three times or ALT levels over five times of upper normal limit had more chances to have CALD (PPV=87.5%) 4) Abnormally increased alkaline phosphatase levels were found in 1.5% and 28.696, and abnormally decreased platelet counts in 3.0% and 20.0% of patients with FLD and CALD, respectively. PPVs of abnormal alkaline phosphatase levels and platelet counts were 77.8% and 90.0%, respectively. 5) All of 29 cases with FLD who lost 3 ㎏ or more of their body weights showed improvement in ALT level;25 of these cases showed normalization of ALT level. In conclusion, RBW, AST, ALT, alkaline phosphatase levels or platelet counts, and trial of body weight reduction may be useful in the differential diagnosis of FLD and CALD in some selected cases; however, differentiation in patients with RBWs between 100% and 120%, and with AST between one and 3 times and ALT between 2 and 5 times of upper normal limit is possible only by liver biopsy.

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