엔로플록사신 액제의 닭 호흡기 및 소화기 감염증에 대한 예방 및 치료효과

윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

We evaluated the efficacy of the liquid form of enrofloxacin against poultry respiratory and digestive infections, the major problems in the poultry industry, from diverse diagnosis viewpoints. Results obtained through this study were as follows: 1. The liquid form of enrofloxacin showed good acceptability to poultry owing to no abhorrence to the drug by chickens, which indicated its suitability for mixing in drinking water. 2. The application of the enrofloxacin formulation improved the productivity of the chicken farm to a great extent by lowering the death toll of chicken raised in the farm. 3. The use of the drug shortened the days to the market, and increased the body weight at the time of marketing. 4. Preventive and therapeutic effects of the liquid enrofloxacin were observed higher than ampicillin, a major antibiotic used in poultry farming. From above results, the liquid form of enrofloxacin would find its use for the prevention and treatment of digestive and respiratory infections, let alone the growth promotion and feed efficiency, especially in the chicken farming practice.

엔로플록사신 액제의 닭유래 병원세균에 대한 시험관내 항균효과 시험

윤효인,박병권,조준형,정상희,박경환,장범수,김종춘,황윤환,임종환,이내경,박승춘 충남대학교 수의과대학 동물의과학연구소 2000 動物醫科學硏究誌 Vol.8 No.-

In this study the antimicrobial spectrum and sensitivity of a liquid formulation of enrofloxacin against the major six pathogenic bacteria isolated from the diseased poultry in Korea were evaluated in comparison with ciprfloxacin (CFX), gentamicin (GM) and penicillin (PC). A liquid form of enrofloxacin, a test material and ciprofloxacin showed at least 83% antibacterial activity against all of six test pathogenic microorganisms at the fixed concentration of 10 ㎍/㎖. Gentamicin and penicillin revealed much lower antibacterial activity at the same condition. We evaluated the liquid form of enrofloxacin as having widespread antibacterial spectrum against poultry infections. The liquid form of enrofloxacin showed potent antibacterial activity, with the MIC range being 0.12∼2 ㎍/㎖ against Gram positives, 0.06∼2 ㎍/㎖ against Gram negatives and 0.5∼2 ㎍/㎖ against Mycoplasma spp. These values were equivalent to or somewhat higher than those of ciprofloxacin, but much lower than those of gentamicn and penicillin. This new liquid form of enrofloxacin would find its way in application of mixing with drinking water for the prevention and treatment of diverse infections in chickens.

구개열 아동 언어의 진단 평가

신효근,고승오,홍기환,서정환,고도흥,김현기 大韓顎顔面成形再建外科學會 1998 Maxillofacial Plastic Reconstructive Surgery Vol.20 No.1

하악골 골절의 견고고정에 사용된 monocortical titanium miniplate와 관련된 감염증에 관한 연구

여환호,김영균,이효빈,김경원 大韓顎顔面成形再建外科學會 1994 Maxillofacial Plastic Reconstructive Surgery Vol.16 No.4

Eighty-nine patients with mandibular fracture were treated by open reduction and internal fixation using the monocortical titanium miniplate(Leibinger Co.). Postsurgical intermaxillary fixation was carried out for 2 to 18 days according to the patient's status. Seven patients developed infections postoperatively(7.9%). Five patients were favorably treated by incision and drainage and/or saucerization. But two patients were not controlled by early surgical intervention and should have been followed by plate removal, saucerization and secondary reconstruction including the bone graft. This article reports the postoperative infection associated with miniplate fixation of mandibular fractures and discuss the incidence, cause, treatment and prognosis with careful case analyses.

본딩 웨이퍼 검사를 위한 모델링 연구

임영환,양시은,장동영,안효석,홍석기 한국공작기계학회 2008 한국공작기계학회 춘계학술대회논문집 Vol.2008 No.-

본 논문에서는 레이저 빔 투과를 이용한 본딩 웨이퍼 검사 방법을 제안하고 검사 장치를 설계 구현하였다. 1064nm파장에서의 정상웨이퍼를 일정한 비율로 투과하였다. 본딩 불량으로 인한 웨이퍼의 기공은 두께에 따라 투과율이 현저하게 변화하여 기공 부분을 검출하였다. 이러한 기공은 두께의 변화가 있으며 광량의 변화하는 부분이 에어갭으로 인식 카메라로 쉽게 구분이 가능하였다.

부분수산법에 의한 PZT 세라믹스의 제작 및 압전특성

남효덕,강성환 嶺南大學校 基礎科學硏究所 1991 基礎科學硏究 Vol.11 No.-

?? (hereafter referred as PZT) powder was prepared by partial oxalate method using ?? powder (hereafter referred as ZTO) and lead nitrate and oxalate powders. The piezoelectric properties of ceramics sintered from the resulting PZT powder at low temperatures were also studied. ZTO powder was derived by hydrothermal processing using both ZrO₂and TiO₂powders at 1100,1200 and 1300℃. The ZTO powder was then dispersed in oxalic acid followed by the addition of lead nitrate to provide intimate homegeneous mixing of lead ions around each ZTO particle. The presence of single perovskite phase of PZT powder which was calcined about 710℃ was revealed from the X-ray diffraction pattern. From particle size analysis, the average particle size produced by partial oxalate method was smaller than that by the conventional mixed oxide technique. The resulting PZT powder was sintered to dense body having the density of 7.9g/㎤ above 1100℃, which is somewhat lower than the sintering temperature by the conventional techniques. The dielectric and piezoelectric properties of PZT ceramics sintered from the powder prepared by partial oxalate method were measured, and the results showed improved properties over the conventional solid-state reaction tchnique. In particular, the powder prepared from the ZTO calcined at 1100℃ proved to be the best among the powders investigated in this study.

무용전공과 고교 및 대학의 직무수행에 따른 지도가치관 분석

한효림,김영환,조방현 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.4

The purpose of this study was to explore the how the dance education is conducted in high schools and colleges consisting of three dance divisions (Ballet, Modern Dance and Korean Dance) in South Korea, and how different each division is related to its pedagogy. Three dance major high school teachers and three college professors were thoroughly observed and interviewed by the researchers. The study draw following conclusions: First, the high school teachers gave more points to student applicants who had the better body figures and potential physical growth, while university professors gave more points to student applicants who had more skills and sincerity. Second, there were no differences in their educational philosophy and value between high school teachers and college professors, Third, all participants of this study indicated that there is a serious problem in dance area, More and more students are likely to choose schools according to the fame of schools, not to their interests and specialties.

간경변성복수와 악성종양성복수의 감별진단에 유용한 지표에 관한 고찰

이효랑,조현덕,김강환,박실무 중앙대부설한국의과학연구소 1991 한국의과학 Vol.23 No.3

Cd_1-xMn_xTe 단결정의 광학적 특성

박효열,진광수,유병길,주정진,김중환 동의대학교 기초과학연구소 1994 基礎科學硏究論文集 Vol.4 No.1

Cd_1-xMn_xTe single crystals were grown by vertical Bridgman method and Mn mole fraction x was determined by the X-ray diffraction. Band gap and optical transition energies E₁, E₁+ △₁, E₂, △₁as Mn mole fraction x were obtained by measuring optical absorption and reflection at UV-visible region respectively. The change of the valence band spin-orbit splitting △₁at △ point of the Brillouin zone was discussed.

우라늄오염에 의한 신부전증에 미치는 제염제의 방호효과

김태환,정인용,김성호,김경중,방효창,류성렬,진수일 대한방사선 방어학회 1990 방사선방어학회지 Vol.15 No.2

원자력산업의 시설증대로 우라늄 오염의 가능성이 증가되고 있음에도 불구하고 종사자 및 국민에대한 안전대책 및 의료적 처치에 관한 연구가 매우 미흡한 실정에 있어 이에 대한 응급처치방안을 수립코자 우라늄을 투여한 후 제염제를 투여하여 관찰하였던 바 다음과 같은 결론을 얻었다. 1. 우라늄오염에 의한 체중변화에 미치는 제염제의 영향에 있어서 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol을 투여한 군에서는 우라늄단독투여군에 비해 체중이 현저하게 증가하였다. (P<0.05). 2. 모든 실험군은 우라늄오염에 의한 음수량과 배뇨량의 변화를 유의성 있게 호전시켰으며(P<0.05), 특히 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol을 투여한 군이 가장 높은 증가경향을 나타냈다(P<0.05). 3. 우라늄오염에 의한 BUN농도 변화에 미치는 제염제의 효과는 sodium bicarbonate와 생리적 식염수를 병행투여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군이 공히 우라늄단독투여군보다 BUN농도가 매우 감소되었다(P<0.01). 4. 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군은 우라늄오염에 의한 serum creatinine의 농도증가를 유의하게 감소시켰으나 (P<0.01), sodium bicarbonate와 생리적 식염수를 병행투여한 군은 다소 감소하는 경향으로 나타났다. 5. 우라늄오염에 의한 urine creatinine농도 변화에 미치는 제염제의 효과에 있어서 sodium bicarbonate와 생리적 식염수를 병행토여한 군과 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군에서는 우라늄단독투여군에 비해 creatinine의 배설이 상당히 증가하였다(P<0.05). 6. 우라늄오염에 의한 신장의 소견에 있어 우라늄단독투여군은 근위곡세뇨관상피의 공포화 및 종창, microvilli와 brush border의 손실, 세뇨관 상피의 괴사가 관찰되었으며, 간장의 충혈, 중심성 괴사 우라늄을 투여하고 30분이 지나서 dithiothreitol를 투여한 군에서는 우라늄단독투여군에 비해 높은 방호효과가 관찰되었으나 다른 실험군에서는 큰 효과가 없는 것으로 나타났다. 결론적으로 우라늄의 체내오염시에는 sodium bicarbonate와 생리적 식염수를 가능한 빨리 병행투여하거나 dithiothreitol을 체내오염후 30분이 지나서 투여하는 방법이 우라늄오염에 대한 제염에 매우 유효할 것으로 생각되며, 특히 우라늄에 의한 인체장해를 유의하게 경감시켜줄 것으로 사료되었다. Appreciable radiation exposures certainly were occurred m the reactor burn-up, the nuelear fall-out and the surroundings of nuclear installations with radioactive effluents. Therefore ,radioactive nuclides is not only potentially hazardous to workers of nuclear power plants and related industrials, but also the wokers who handle radioactive nuclides in biochemical research and nuclear medicine diagnostics. And in the case of occurring the nuclear accidents, the early medical treatment of radiation injury should be necessary but little is established'medical procedures to decontaminate the victims of internal contamination of radioactive nuclides in korea. Accordingly, to achieve the basic data for protective roles and medical treatment of radiation injury, the present studies were can-id out to evaluate the decontamination of uranium by the chemical drugs. The results observed were summarized as follows : 1. The combined treatmet group of sodium bicarbonate and saline with uranyl nitrate injection simultaneously and the dithiothreitol group that was administered 30 minutes after uranyl nitrate injection were increased significantly in the change of body weight than uranyl nitrate-only group(P<0.005). 2. All the experimental groups were increased the fluid intake and urine volume on the uranyl nitrate-induced acute renal failure, but the combined treatment group of sodium bicarbonate and saline with uranyl nitrate injection simultaneously and the dithiothreitol group that was administered 30 minutes after uranyl nitrate injection have the higher increment of fluid intake and urine volume(P<0.05). 3. When sodium bicarbonate and saline was treated with uranyl nitrate injection simultaneously, and dithiothreitol was administered 30 minutes after uranyl nitrate injection, there was significantly reduced in BUN concentration (P<0.0l). 4. When dithiothreitol was administered 30 minutes after uranyl nitrate injection, there was reduced more significantly on the increment of serum creatinine concentration than that observed in uranyl nitrate-only group(P<O.Ol). but when the combined treatment of sodium bicarbonate and saline with uranyl nitrate simultaneously, there was still, albeit much less marked, decrease in serum creatinine concentration. 5. The sodium bicarbonate and saline was treated with uranyl nitrate simultaneously and dithiothreitol was administered at 30 minutes after uranyl nitrate were excreted markedly higher urine creatinine concentration than the uranyl nitrate-only group. 6. Uranyl nitrate has been used in experimental animals to produce hydropic degeneration and swelling of proximal tubules, disappearance of microvilli and brush border or necrosis in the kidney and centrilobular necrosis, congestion, and telangiectasia of the liver. When the sodium bicarbonate and saline was treated with uranyl nitrate simultaneously, and dithiothreitol was administered 30 minutes after uranyl nitrate, there was more marked the protective effect than uranyl nitrate-only group. Finally, if the sodium bicarbonate and saline may administered as quickly as possible each time that some risk for internal contamination with uranium, and dithiothreitol is administered 30 minutes after uranium contamination, there ameliorates the course of uranyl nitrate-induced acute renal failure,and this effect is assocciated with prevention of uranium (heavy metal) induced alterations in BUN. serum creatinine. urine creatinine. fluid intake, urine volume and body weight.