전력 소모를 감소시키기 위한 게이트 크기 재결정에 관한 알고리즘 연구

鄭均樂,李炯日 弘益大學校 科學技術硏究所 1999 科學技術硏究論文集 Vol.10 No.1

The gate resizing is the problem of finding load drive capabilities of all gates such that a given delay limit is satisfied and the total cost in terms of area and/or power consumption is minimal. After this step, power consumption can be further reduced by gate resizing - larger gates are replaced by smaller ones that have higher delay but lower power consumption and the circuits timing constraints are still obeyed. In this paper, we have proposed new algorithm for gate resizing problem which is superior to Chen's algorithm.

加味牛膝湯이 實驗動物의 鎭痛에 미치는 影響

金炯均,權文鉉,오로사,金成宰,李彦政,李峰根 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

뇌공승 煎湯液이 마우스의 免疫抑制에 미치는 影響

明成俊,金炯均,宋峰根 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1

비유기중의 소유방염에 대한 항균펩타이드(Buforin Ⅱb)의 효능실험

김인송,권성균,임형준,이완규 한국수의공중보건학회 2002 예방수의학회지 Vol.26 No.3

Recently, a novel antimicrobial peptide including Buforin II has been emphasized to kill multi-drug resistant bacteria and avoid promoting multi-drug resistance. This study evaluated the efficacy of an antimicrobial peptide (Buforin IIb) on bovine mastitis. Based on the Minimum inhibitory concentration(MIC, 4 g/ml) of Buforin IIb, syringes were made five concentration(MIC×10, ×50, ×100, ×300, and ×500). Thirty three cows(38 quarters) with bovine mastitis were selected using California mastitis test and grouped in dependant on drug concentration and treatment duration. Each group treated by intramammary infusion twice a day for 3 5 days. The milk samples of 5 groups were aseptically collected from quarters at 0, 3, 7 and 14 days, and 2 groups were collected at 0, 5, 9 and 14 days after first treatment. Collected samples were used for bacterial culture and somatic cell count. Bacterial number(log_(10) mean CFU/ml) was decreased in dependant on drug concentration and extending treatment duration. In group D(MIC×300), bacterial number was decreased from 4.59±0.10(day 0) to 2.89±1.37(day 3), 4.04±0.33(day 7), and 4.19 ± 0.10(day 14), respectively(p 0.05). Bacterial number of B2(MIC×50, 5 days treated) is decreased, approximately 10%, than group B1(MIC×50, 3 days treated). Somatic cell count of group D was slightly decreased from 11,100(×10³)(day 0), to 7,386(×10³)(3 day), 6,886(×10³)(day 7), and 9,661(×10³)(day 14). Staphylococcus spp., was the most common isolate, was bacteriologically cured 100% by Buforin IIb treatment. Overall results indicate that Buforin IIb could have possibility to cure bovine mastitis, if higher concentration over experimental concentration were treated with extending treatment duration.

薏苡仁의 投與가 마우스의 細胞性 및 體液性 免疫機能에 미치는 影響

우영은,김형균,송봉근,이언정 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

Coicis Semen is one of the oriental medicine that has been used for the treatment of the disease such as pulmonary abscess, periappendicular abscess and wart since ancient times. However, the mechanism of the action of the drug is not well studied. This study was done to investigate the effects of Coicis Semen on the host defense mechanism. Effects of Coicis Semen on the immune responses were analyzed by measuring the contact gypersensitivity, hemagglutinin, hemolysin and rosette formation, cytotoxicity, and reactive oxygen intermidiates production. As the results, water extract of Coicis Semen administration enhanced the antibodies (hemagglutinin and hemolysin) formation and the appearance of rosette forming cells of the spleen. Also Coicis Semen increased the allogeneic immune response in the mouse, showed cytotoxic activity against human leukemia cell line(K562) and decreased the contact hypersensitivity against dinitroflurobenzene. Also administration of Coicis Semen slightly increased NK cell activity and enhanced the production of such reactive oxygen intermidiates as superoxide and hydrogen peroxide from the macrophages in vivo and in vitro. The above results demonstrate that Coicis Semen has enhancing effects on cellular and humoral immune responses against disease.

甘草와 뇌공승합제 煎湯液이 마우스의 免疫抑制에 미치는 影響

權文鉉,金炯均,李彦政 圓光大學校 韓醫學硏究所 1994 원광한의학 Vol.4 No.1

汚加皮 抽出液이 마우스의 抗腫瘍 免疫反應에 미치는 影響

成載煥,權文鉉,金炯均 圓光大學校 韓醫學硏究所 1995 원광한의학 Vol.5 No.1

Ogapi(Acanthopanax senticosus) is being used for a tonic in the oriental medicine from ancient times, Even though it being used frequently for a tonic in the clinical medicine, basic study to make sure the mechanism of its action is the rare. Therefore, in this study, the author tried to know the effects of ogapi on the innate and specific immune systems in association with antitumor activity. The results obtained in this study are as follows: 1) Ogapi increased the phagocytic activities of murine peritoneal macrophages in vivo and in vitro. 2) Ogapi enhanced the production of such reactive oxygen intermediates as superoxide and hydrogen peroxide from the macrophages in vivo and in vitro. 3) Ogapi enhanced such humoral immune responses as hemagglutinin and hemolysin formations. 4) Administration of ogapi increased the number of rosette forming cells in the spleen. 5) Ogapi decreased the contact hypersensitivity against dinitrofluorobenzene. 6) Ogapi showed cytotoxic activity against human leukemia cell line (K562) 7) Ogapi increased the ratio of helper T cell versus suppressor T cell by increasing CD4^+ T cells and decreasing CD8^+ T cells. The above results show that ogapi increase the host antimicrobic and antitumor activities by the action on individual innate and specific immune systems in vitro. So this is considered as experimental results back up powerfully that ogapi can be used for a tonic in such a case when administered to a person lacking vital energy.

枳實에 의한 아나필락시의 抑制效果

李彦政,朱泓炫,金炯均,宋峰根 圓光大學校 韓醫學硏究所 1996 원광한의학 Vol.6 No.1

The effect of water extract of Poncirus trifoliata fruit (ATFE) on compound 48/80 induced anaphylaxis was studied in the rat. The following results have obtained. 1. Optimal lethal dose of compound 48/80 was 8ug/gm B.W. 2. PTFE was found to exhibit an inhibitory activity on the anaphylaxis induced by compound 48/80. 3. Administration of PTFE 60 min before or 5 min after had a better result than 10 min after anaphylaxis induced by compound 48/80. 4. PTFE also inhibited significantly the serum histamine release in anaphylaxis induced by compound 48/80 in the rat. 5. Administration of PIFE before 30 min decreased PCA reaction induced by anti DNP-IgE and DNP-HSA. This result indicates that poncirus trifoliata suppresses the anaphylaxis induced by compound 48/80 with decreasing the serum histamine release.

중추에서 Prostaglandin계가 Renin-angiotensin System에 미치는 영향

최영태,김종승,문성호,오형균,김재훈,전제열,염철호,윤평진 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.1

Role of prostaglandins on the renin-angiotensin system in the central nervous system was examined in normotensive and 2-kidney, 1 clip (2K1C) hypertensive rats. The experiment was done under thiopental (50 ㎎/㎏, IP) anesthesia. Captopril and indomethacin were injected into the right lateral cerebral ventricle. Arterial blood pressure and heart rate were recorded from the femoral artery. Intracerebroventricular (ICV) captopril (1 ㎎) caused a decrease in mean arterial pressure in both normotensive and 2K1C hypertensive rats. The depressor response to captopril was more sensitive in hyper-tensive rats than in normotensive rats. Indomethacin treatment (ICV, 200 ㎎) altered the depressor response to captopril neither in normotensive nor in hypertensive rats. These results suggest that the cardiovascular effect of renin-angiotensin system in the central nervous system may not be mediated via prostaglandin systems in normotensive and 2KlC hypertensive rats.

동적 채널 할당을 윈한 무선 중계 시스템

장자영,노순국,김송민,김재섭,허영팔,박창균 조선대학교 동력자원연구소 1997 動力資源硏究所誌 Vol.19 No.1

Being adopted the Cellular Systems in Korea, the method of a radio repeater is that the mobile station(MS) can be used only in a service area of the base station(BS). In case that traffic congestion is occured around the specific BS because of an event etc., the traffic blocking rates are being maximized and the subscriber service is being dropped. To improve these problems, we propose an algorithm for a radio repeater network that distributes the traffics of the specific BS, predicted traffic congestion, to an adjacent BS by sharing a service area. And then, we confirm the valid through the simulation.