http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Pancytopenia in pregnancy woman with upper respiratory infection
( Yoon Hyeon Hu ),( Tae Yeon Kim ),( Tae Gyu Ahn ),( Hyang Ah Lee ),( Sunghun Na ),( Jong Yun Hwang ),( Dong Hun Lee ),( Se Jin Lee ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Pancytopenia is reductions in all the three major cellular components of blood, and it is the simultaneous presence of anemia, leukopenia, and thrombocytopenia. It complicating pregnancy is rare. But during pregnancy it could be life-threatening for both mother and child. Pancytopenia, which occurs early in pregnancy, is particularly challenging in clinical settings because pregnancy management and outcomes are entirely dependent on underlying causes. The assessment of patients with pancytopenia requires a comprehensive approach and it can be difficult to determine the root cause when considering various causes, including drugs, autoimmune conditions, malignancies, infections, hemophagia, and inheritable conditions. While bone marrow failure syndromes and malignancies are important causes, certain non-malignant conditions such as infection and nutritional anemia are equally important causes. We present a 29-year primigravida woman with an uneventful medical history who was referred at 17weeks gestational age as a case of fever with pancytopenia. She had a cough and sore throat. And serum C-reactive protein and procalcitonin levels were elevated. She was admitted, investigated and diagnosed as a case of pancytopenia with peripheral blood smear showing normocytic normochromic anemia with aniso-poikilocytosis, leukopenia with lymphopenia (10%190/uL), and moderate thrombocytopenia. She was treated intravenous antibiotics and after the infection has been cured, the pancytopenia has improved spontaneously after 3 weeks later. We report a case who developed pancytopenia following upper respiratory infection in the rare case.
( Yoon Hyeon Hu ),( Yung-taek Ouh ),( Chorong Kim ),( Se Jin Lee ),( Tae Gyu Ahn ),( Hyang Ah Lee ) 대한폐경학회 2021 대한폐경학회지 Vol.27 No.2
Spontaneous rupture of an ovarian artery aneurysm is an extremely rare, life-threatening disease and has been reported to be most highly associated with pregnancy. The current study presents a case of intraperitoneal and retroperitoneal hematoma caused by spontaneous rupture of a right ovarian artery aneurysm in a 56-year-old woman. A 56-year-old woman visited the emergency room with right lower quadrant abdominal pain. Contrast-enhanced computed tomography showed a large retroperitoneal and intraperitoneal hematoma and active extravasation of contrast medium in the right retroperitoneum. Consequently, transcatheter arterial embolization was successfully performed. Spontaneous rupture of an ovarian artery aneurysm should be suspected in multiparous women with abdominal or flank pain even if it is unrelated to pregnancy. Suspicion of this entity is needed for earlier diagnosis and management.
( Yoon Hyeon Hu ),( Dong Hun Lee ),( Jong Yun Hwang ),( Sunghun Na ),( Tae Gyu Ahn ),( Yung-taek Ouh ),( Se Jin Lee ),( Chorong Kim ),( Darae Lee ),( Hyang Ah Lee ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
Objective: Child sexual abuse (CSA) is a global problem that affects children of all ages, and the evaluation of these victims by psychologic and gynecologic experts in pediatric emergency departments is an important issue. Few data are available on the characteristics of children admitted to sexual assault centers during the acute phase of sexual assault injury within 72 hours. Methods: From 2007 to December 2014, a total of 270 female patients who were 18 years of age or younger with a diagnosis of CSA were evaluated at Kangwon National University Hospital Sexual Assaults Center. We analyzed 158 cases which were complete with the time from occurrence to visit, characteristics of victims, victims behaviors, assailants, and types of abuses that occurred. We classified the victims into two groups: those who visited the center within 72 hours and those who did not. Results: Mean days from occurrence to visit were 1.05 days for victims who utilized medical services during the acute phase of sexual assault injury, and 34.43 days for victims who visited during the post-acute phase (delayed exposure). Victims with a physical sexual assault involving penetration showed a higher proportion of visit within 72 hours of the occurrence. In logistic regression, victims with single mother(OR=0.199), single father(OR=0.088), grand or stepparents or relatives(OR=0.147) were significantly less likely to visit during the acute phase in comparison to victims with both parents. Conclusion: The type of family and the presence of physical injuries are considered to be significant factors affecting CSA victims visiting medical institutions within three days.
Anaphylactic shock following intravenous ranitidine in pregnancy woman
( Yoon Hyeon Hu ),( Tae Yeon Kim ),( Tae Gyu Ahn ),( Hyang Ah Lee ),( Jong Yun Hwang ),( Dong Hun Lee ),( Se Jin Lee ),( Sunghun Na ) 대한산부인과학회 2019 대한산부인과학회 학술대회 Vol.105 No.-
Ranitidine is generally safe in pregnancy. Anaphylaxis is rarely observed with ranitidine. Anaphylaxis is triggering maternal hypotension leading to intrapartum hypoxic-ischemic encephalopathy in the infant. Furthermore, cesarean sections are performed at a high rate of anaphylactic pregnant woman. A 43-year-old primigravida was hospitalized for a cesarean section at 38+3 weeks of gestation. She didn’t have any underlying disease. She had histories of drug allergy for common cold medication. But she didn’t know exactly what drugs were causing allergies. Following admission, before the cesarean section, ranitidine was injected to her. At the beginning of the injection, the patient complained of dizziness, and within seconds she experienced shortness of breath and chest tightness. Several minutes later she experienced dyspnea, sweating, and severe cramping pain in the abdomen. Further, the fetal heart revealed bradycardia (70-80 beats per minute). She has received an emergency cesarean section under general anesthesia. A male infant weighing 3220 g was delivered with Apgar scores of 2 and 3 and 4 at 1, 5 and 10 minutes. The infant was transferred to the neonatal intensive care unit. After the surgery, the mother was received routine post-operation care and discharged home. We report a case who developed severe anaphylaxis following a single dose of intravenous ranitidine in the rare case.
Antioxidant Activities of Various Extracts of Hovenia dulcis Thunb Fruits
Hu, Weicheng,Lee, Kab-Yeon,Wang, Myeong-Hyeon The Plant Resources Society of Korea 2010 한국자원식물학회지 Vol.23 No.3
Hovenia dulcis Thunb fruits were successively extracted with hot water, water, methanol, ethyl acetate, and chloroform. The crude extracts were investigated for potential antioxidant by measuring scavenging against DPPH free radicals, reducing power, superoxide radicals, and protection of protein damage and cultured cells from a lethal dose of hydrogen peroxide ($H_2O_2$). In all chemical assays used, the hot water extract of H. dulcis fruits, which contained $61.14{\pm}2.57$ (Tannic acid mg/g extract, n=3) of total phenolic compounds contents exhibited highest activity in in vitro models of DPPH free radical scavenging activity, reducing power assay, superoxide radical scavenging activity and protection of protein damage. In addition, the hot water extract protected cultured RAW 264.7 macrophages from a lethal dose of $H_2O_2$ and reduced reactive oxygen species level in RAW 264.7 cells.
Hu, Weicheng,Han, Woong,Jiang, Yunyao,Wang, Myeong-Hyeon,Lee, Young-Mee The Korean Society of Food Science and Nutrition 2011 Preventive Nutrition and Food Science Vol.16 No.3
The methanolic extract of Rosa davurica Pall. roots exhibited strong antioxidant activity in a 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay and was found to be a dose-dependent inhibitor of non-enzymatic formation of advanced glycation end products (AGEs), which are relevant to diabetes complications. HPLC-diode array detector (DAD) analysis of the R. davurica Pall. root extract led to the identification of four compounds: hydrocaffeic acid, catechin, epicatechin, and ellagic acid. Catechin was present in the largest amount and exhibited high antiglycation activity. A CYP3A4 assay was used to investigate potential interactions between drugs and the extract, and results suggest that the R. davurica Pall. root extract had moderate potential for interfering with drug metabolism. The R. davurica Pall. extract did not display anti-inflammatory activity on the level of that for tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) in a lipopolysaccharide (LPS)-stimulated macrophage assay; however, the extract did exhibit low to moderate immunostimulatory activity in a pro-inflammatory macrophage assay. Therefore, we conclude that R. davurica Pall. root is a promising anti-AGE agent with low to moderate risks of associated inflammation or drug interaction.