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      • 초산모의 분만유형과 모성관련지식에 관한 연구

        김혜란,노진아,손은정,이명아,김증임 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

        Purpose: This study was to know primipara's general characteristics, delivery type, delivery characteristics, maternity related knowledge level, and relation of delivery type and maternity related knowledge level. Method: This is a survey. Subjects were sixty primiparas who had admitted to a pediatric outpatient clinic at general hospital in Seoul. Subject's age was ranged from 15 to 44 and it was lapsed 10 weeks after delivery of their first baby. Maternity related knowledge level was measured by "primipara's maternity related knowledge level". Data was nalyzed using frequency. percentage, mean, standard deviation, ANOVA, t-test by SPSS 11.0. Result: Relation of delivery type and maternity related knowledge in primipary did not show a statistically significant. But the relation of natural delivery and maternity related knowledge in primipara was a littlehig than that of caesarean section. Conclusion: There is no significant diference of maternity related knowledge between natural delivery and caesarean section. We suggest for randomized clinical trials with a larger sample size.

      • 스트레스가 지방산 조성이 다른 식이를 섭취한 흰쥐의 면역 기능에 미치는 영향

        최정순,나혜복 서울여자대학교 자연과학연구소 1996 자연과학연구논문집 Vol.7 No.-

        본 실험에서는 stress가 지방산 조성이 다른 고지방식이를 준 Spague Dawley종 흰주 23마리의 면역기능에 미치는 영향을 알아보고자 하였으며 식이지방으로는 옥수수유와 참치유를 20%수준으로 7주간 공급하였다. Stressor로는 쥐 cage를 4/5정도 차단하여 외부와의 고립감을 느끼도록 하였으며 이들의 영향을 알아보기 위하여 체중, 식이효율, 장기 무게와 mitogen을 사용하여 면역능력을 측정하였고 다음과 같은 결과를 얻었다. 1. 체중, 체중증가및 식이효율은 stress에 의한 영향은 없었으나 지방의 종류에 의한 차이를 보였으며 참치유를 섭취한 군에서 유의적으로 낮았다. 2. 장기무게중 stress에 희해 간의 무게는 유의적인 증가하였으면 adrenal gland, 체중당 adrenal gland무게는 감소하였다. 식이지방에 따라 체중당의 간, spleen, adrenal gland무게에서는 옥수수유군이 참치유군보다 유의적으로 낮게 나타났으며 thymus의 경우는 옥수수유군에서 높은 값을 나타내었다. 3. Stress에 따른 면역기능을 알아보기 위하여 mitogen으로써 ConA를 처리한 경우에는 면역세포의 증식이 낮아졌으면 PHA의 경우에는 면역세포의 증식이 활발해지는 경향을 보였다. 식이지방으로는 옥수수유군에서 높은 경향을 나타내었다. PHA/ConA ratio 경우는 전반적으로 stress에 의해 약간 증가하는 경향을 나타내었다. 4. 세포내 단백질 합성능력은 유의적인 차이를 나타내지 않았으나 stress에 의해 대부분의 mitogen으로 유도한 면역세포 증식반응이 낮아졌다. 식이지방으로는 참치유군에서 높은 경향을 나타내었다. 이상의 결과를 종합해보면 식이지방의 종류와 stress가 면역기능을 담당하는 기관의 무게에 영향을 주는 것으로 나타났으며 면역능력에는 유의적인 영향을 나타내지 않았으나 stress에 의해 면역능력이 증가하는 경향을 보였고 참치유군보다는 옥수수유군에서 면역능력이 높은 경향을 보였으며 이들에 대한 좀 더 활발한 연구가 필요하다고 사료되어진다. This study was concerned to investigate the effect of stress on the immune responses in rats with different dietary fats. 23 male Sprague-Dawley rats, weighting 65-75g, were fed two different types of dietary oils for 7 weeks. For sterss rats made to feel isolation in the outside intercept rat cages by 4/5 degree and immune capacity is measured to use body weight, food efficiency ratio, organ weight for showing those effect. 1. Body weight, weight gain and food efficiency ratio had no effect on stress, but these were significantly low for group which gives tuna oil. 2. In organ weight, weight of liver increased significantly, and adrenal gland, adrenal gland index decreased by stress. Liver index, spleen, adrenal gland index in corn oil fed group were lower than the result of tuna oil group. In the case of thymus in corn oil fed group was higher than tuna oil group. 3. According to stress, ConA-induced lymphocyte proliferation was decreased but PHA-induced lymphocyte proliferation was increased in immune capacity. In the cases of dietary fat corn oil group was higher than tuna oil PHA/ConA ratio seemed to increase by sterss. 4. Cell protein synthesis capacity have no significant difference but a major portion of mitogen induced lymphocyte proliferation decreased. The capacity of tuna oil group was higher than corn oil group in dietary fats. A sort of dietary fat and sterss had an effect to weight of immune response organ, and those had no significant effect to immune capacity. Immune capacity seemed to increase by stress, the result of corn oil group was higher than the result of tuna oil group.

      • SCOPUSKCI등재

        원예치료와 원예복지 그리고 식물치료에 관한 소고

        곽병화,서정근,곽혜란 韓國植物ㆍ人間ㆍ環境學會 1999 인간식물환경학회지 Vol.2 No.3

        Horticultural activities comprise with culture and care of either vegetables, fruits, flowers or other ornamental Plants, although horticulture hitherto is known for income-making business, it is recently widely known to bring out amenity living and emotional influence on those much isolated from nature and ruthless urban living. Horticulture upgrading human life quality is thus reflected as human well-being through horticulture. Horticultural practice is known vastly desirable for in healing modem diseases as disabled, mental disordered, dementia, etc. and now is enlightened as horticultural therapy, Plant watching and appreciation with own culture and care imply human well-being through plants, otherwise is recognized as plant therapy for the healing dimensions without one's own cairo.

      • 식품 기준·규격의 합리적 관리 ·운영에 관한 연구(Ⅰ) : 두부,식용유지, 전분의 분말상 원료에 관하여 Powdered marerials of Tofu, Edible oil, Starch

        김희연,홍진환,박혜경,한상배,박종석,이은주,이정성,송경희,최은희,최영준,소경아,성영제,이주엽 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

        본 연구는 분말상 원료(전분, 대두분)의 저장유통시 품질변화를 건전성과 안전성 측면에서 검토하여 식품의 기준 ·규격 설정f.」 합지적으로 반영하고자 하였다. 전분과 패두분의 이물을 검사하고, 2종 대두분(중국산, 미국산)을 ?0일간 IS'c와 30t에 저장하면서 성상, 수분, 산가, 과산화물가, 지방산 조성,아플라톡신 BB의 생성여부를 분석하였다. 중국산 대두분 30'』 저장군에서 50일 이후 곰팡이가 발생한 것 이외에 모든 시료에서 양호한 성상을 나타내었고, 전분과 대두닥 모든 시료에서 이물은 검출되지 않았다. 산가는 중국산과 미국산 시료간에 편차를 보여 증국산 30"C, 50일 저장시료에서 약 10배끙도 증가하였고, 과산화물가는 저장 90일후 15'E 저장군은 약 2.3배, 30'c 저장군은 3배정도 증가하였다. 대두분의 주요 지방산은 linoleic acidf18. 2), oleic acid(18 : 1), palmitic acid(16 : 0)이었으며, 3개월 저장에 따른 지방산 함량의 변화는 미미하였다. 아플라톡신 B₁은 모든 시료에서 검출되지 않았다. The objective of this study was to investigate auality changes of type raw materials(starch, soy flour) during various storage conditions. Starchflour(source of China, U.S.A) were slfred under two temperature(15'C, 30'c) forSensory evaluation, (o.reign material test, moisture content, acid value, peroxide ualue,composition, aflatorin Bi were analyzed. China soy flour(stor·ed 30'f) was contaminated by fungj on 50 days. Except for soy flour contardnated by fungi, sensory characteristics were not changed and foreign mater;als were notdetected. Acid value of China soy flour(stored at 30'C, 90 days) was about 10 times higherlevel before storage and acid value was more influenced by source(China, USA). Peroxide valuewas in proportion with the storage period slightly. The major fatty acid of soy flour waslinoleic acid(18 . 2), an(3 the change of fatty acid composition was not observed. Aflatoxlrl Blwas not detected.

      • KCI등재

        기분 장애 환자에서 나타나는 불특정 CAG 삼핵산 반복서열의 확장

        손성은,임신원,이소영,황혜진,진동규,박정의,김도관,김이영 대한신경정신의학회 2000 신경정신의학 Vol.39 No.2

        연구목적: 기분장애는 그 원인과 발생기전은 아직 밝혀져 있지 않고 있지만, 과거부터 유전적 요인이 질병의 발생과 중요한 연관성을 가지고 있다고 알려져 있다. 특히 양극성 정동장애는 가족력이 있는 경우에 발병될 가능성이 높고, 같은 가족 내에서 발생했을 때 세대가 내려감에 따라서 발병시기가 점차 빨라지며 증세가 심해지는 경향이 있어서 그 유전적 배경에 대해 많은 의문이 있어 왔다. 연구자들은 다양한 증상의 기분장애 환자들의 DNA에서 불특정 CAG 삼핵산 반복(trinucleotide repeat. TNR) 정도를 분석함으로써 TNR 확장이 기분장애의 유전과 관련되는지 살펴보았다. 방법: 환자 군은 DSM-Ⅲ-R 진단기준에 의거하여 양극성 정동장애(N=55), 주요우울장애(N=67) 환자들을 선발하였다. 정상인(N=89)은 정신과적 병력이 없고 다면성 인성검사상 정상의 profile을 나타내는 병원 종사자, 학생 및 건강의학센타 방문자들 중 선발하였다. TNR의 확장은 genomic DNA를 순수분리한 후, (CTG)₁□의 oligonucleotide를 □-□□P-ATP로 방사선 표지하여 반복서열 확장 탐지법(repeat expansion detection)으로 측정하였다. 집단간의 비교를 위해 Mann-Whitney U 검증을 실시하였다. 결과: DNA에서 관찰되는 불특정 CAG 삼핵산 반복 길이의 평균은 양극성 정동장애에서 169.8bp(S.D=58.6), 주요우울장애에서 167.5bp(S.D=63.9)로서 대조군 178.7bp(S.D=56.5)과 비교하였을 때 유의미한 차이는 관찰되지 않았다. 각각의 환자군을 가족력이 있는 군과 없는 환자군으로 나누어 대조군과 비교하였을 때도 유의미한 차이는 관찰되지 않았다. 결론: 불특정 CAG 삼핵산 반복서열 확장이 양극성 정동장애 환자와 주요우울장애 환자들의 유전 양식에 영향을 미친다는 가설을 뒷받침하지 않는다. Objectives: The genetic facotrs have been suggested for the etiology of mood disorders but the mode of inheritance is complex. Increased severity and an earlier onset of the bipolar and major depressive disorder over generations within families(Anticipation) were reported. In order to test the hypothesis that trinucleotide repeat expansions underlie the genetic basis of Bipolar and major depressive disorders, we have analyzed the extent of CAG reapeats in genomic DNA from mood disorder patients. Methods: 55 bipolar disorder, 67 major depressive disorder patients were recruited accord-ing to the DSM-Ⅲ-R criteria. 89 normal controls were recruited from the medical personnel, students and the visitors to the health services center who had no history of psychiatric illness and show normal profile of MMPI. The genomic DNA of patients and controls was analyzed by use of the (CTG)□ oligonucleotide and the repeat expansion detection(RED) method. The Mann-Whitney U test was used to compare the distribution of the number of CAG repeats among the groups. Results: when the bipolar disorder, major depressive disorder patients were compared with the control group, no significant differences were observed. Conclusions: Our results do not support the hypothesis that expanding CAG repeats are causing the observed genetic anticipation in bipolar disorders and major depressive disorders.

      • 한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

        양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

      • SCOPUSKCI등재

        Antitumor Effects of Glycoprotein Extracted from Sea Cucumber (Stichopus japonicus)

        Jeung-Hye Moon,Hong-Soo Ryu,Jae-Soo Suh 한국식품영양과학회 1999 Preventive Nutrition and Food Science Vol.4 No.2

        The antitumor and immunologic activities of the glycoproteins extracted from sea cucumber (Stichopus japonicus) on mice bearing sarcoma 180 cells were investigated. Maximum tumor suppression (64%) occurred at the dose of 100 ㎎ glycoprotein/㎏. The highest prolongation ratio was achieved at the level of 100 ㎎/㎏ and increased by 39% more than that of control. Glycoproteins from sea cucumber exhibited direct cytotoxic effect on the tumor cells. Dose-dependent increase of leucocyte, peritoneal exudate cell and weights of immunoorgans revealed the improvement of immunity. When the glycoprotein-administered group was compared with the control, a significant difference was not noted in the clinico-chemical values such as S-GOT, S-GPT, alkaline phosphatase activity, total protein, cholesterol, triglyceride, urea nitrogen and glucose levels in blood. These results suggest that the antitumor activity of sea cucumber glycoprotein is associated with activation of cells in the immune system.

      • Exploring the Creative Teaching-Learning Method to Promote Introspective Thinking Ability

        Hye-Jeung Lee 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.10

        The purpose of this study is to explore the possibility of reflective writing as a creative teaching-learning method to promote introspective thinking of pre-service teachers. Reflective writing is a new method to understand one’s points of view on the world. Reflective writing refers to reflecting process on writers’ previous writing experiences, which reveals cognitive and emotional process. Reflective writing provides researchers with the data which is impossible to be recognized from result text, and it also offers the opportunity to develop systematic thinking ability. In these regards, reflective writing has the possibility of the creative and ingenious research method. The results of this study show that reflective writing provides pre-service teachers with the opportunity to scrutinize their attitudes and belief on education. It can also provide meaningful data for educators to understand their students’ perception on education and help to organize the effective teaching project to customize their students’ needs and interests.

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