자궁경부 상피내 병변 환자에서 LEETZ 원추절제술 후 HPV DNA Test 추적 검사의 임상적 의의

김미향,이태화,오영림,이천준,김원규 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.2

Objective: This study was performed to investigate the clinical significance and timing of HPV test for follow up of patients after LEETZ treatment in CIN lesion Methods: From January 2005 to December 2008, 105 patients with CIN were treated with LLETZ at Kosin university gospel hospital, Busan, Korea. After LEETZ, HPV test and Pap smear were done after 3months. Every HPV typing was done by HPV DNA chip. Results: A total of 105 cases were enrolled in this study. There were 25 patients with CINⅠ, 38 with CINⅡ, 42 with CINⅢ. Mean age was 41.95 years (range, 23-71 years) at the time of LEETZ. Positive HPV DNA was found about 72.4% before LEETZ procedure and subtype 16 was the most common type (10.5%), follow by subtype 18 (6.6%) and subtype 58 (6.6%). During follow up after LEETZ, 65.6% had negative result after 3 month, 72.1% after 6 month, 73.9% after 9 month, 77.1% after 12 month, 79.2% after 15 month, 79.6% after 18 month, and 80.4% after 24 month. There were 2 cases of abnormal pap smear among persistent positive HPV DNA cases and no abnormal pap smear results in negative HPV DNA cases during follow up. Conclusion: Positive HPV DNA was found about 72.4% before LEETZ procedure and subtype 16 was the most common type (10.5%), follow by subtype 18 (6.6%) and subtype 58 (6.6%). We suggest that HPV DNA test is recommended per 6 Months, and close observation is recommended in persistent positive HPV DNA test cases.

상 요추 추간판 탈출증의 수술적 치료

조태현,송준혁,김명현,박향권,김성학,신규만,박동빈 梨花女子大學校 醫科大學 醫科學硏究所 2000 EMJ (Ewha medical journal) Vol.23 No.3

Objectives : Lumbar disc herniations at the L1-L2, L2-L3, and L3-L4 level are rare. The purpose of this study is to observe the variable clinical finding of upper lumbar disc herniations and to provide proper treatment modality. Patients and Methods : Between 1998 Jan. and 1999 Dec., seventeen patients with upper lumbar disc herniations who were undergone surgery in our institute were retrospectively evaluated. Patients were evaluated based on following factors : age, sex, aggravating factor, symptoms and signs type of disc herniation, type of surgery, and outcome of post-surgery. Results : The incidence of lumbar disc herniation at the level of L1-2, L2-3 and L3-4 is 6.1% with declining frequency as the level ascends. The peak age incidence is 6th decade in both sex. Preoperative symptomes and signs are variabe. In sixteen cases, posterior approach was done. In these cases, twelve cases were performed microscopic partial hemilaminectomy, and four cases with spinal stenosis were performed total laminectomy and posterior screw fixation with bone fusion. In one case, lateral extracavitary approach was done. In results of operation, fourteen cases showed more than good grade(82%). Conclusion : The age incidence of lumbar disc herniations at the level of L1-2, L2-3 and L3-4 older than lumbar disc herniations at the lower level of L4-5 and L5-S1. The signs and symptoms are variable. In our cases, most of the patients were performed posterior approach with microscopic partial hemilaminectomy except the patients combined spinal stenosis. One case was performed a lateral extracavitary approach because the risk of the cord and cauda equina injuries. The prognosis of upper lumbar disc herniations after treatment with only microscopic partial hemilaminectomy and diskectomy is comparable with the prognosis of lumbar disc herniations at the lower level.

濟州地域 觀光所得 殘留效果 提高方案 : 第1次産業과의 連繫性 강화 및 觀光費用分析을 중심으로

金泰保,許香珍 濟州大學校 社會發展硏究所 1988 社會發展硏究 Vol.4 No.-

Enamel matrix derivative(EMDOGAIN^(R))을 이용한 상악 소구치의 자가이식 치험례

오유향,김효식,정현구,조태식,위유민,이창섭 조선대학교 구강생물학연구소 2002 Oral Biology Research (Oral Biol Res) Vol.26 No.2

The success of tooth transplantation or replantation depends on the viability of periodontal ligament in the transplanted tooth. Mechanical injury to periodontal tissues frequently results in dental root resorption and ankylosis, which leads to the failure of transplantation or replantation. Enamel matrix derivative (EMD) has been recently used to induce periodontal regeneration. In this report, we show a clinical case of EMD application in the transplantation of an inversely impacted and immature tooth. An impacted second premolar was found in the right maxilla of a 14 year-old girl. The tooth was inversely impacted and the root formation was incomplete. When transplantation was carried out. EMD was applied to the periodontal tissues of the extracted premolar. The tooth was fixed at the correct position and the clinical condition was followed for evaluation for 3 months. Radiographs after 3 months exhibited new bone formation surrounding the transplanted tooth. There were no signs of root resorption or ankylosis, and reconstruction of the bone defect area at the maxilla was also found. Short-term results from this case indicated that EMD application was effective in the transplantation of an inversely impacted and immature tooth. In adddition, EMD might contribute to obtain good healing without ankylosis. Further follow-up observations are necessary to evaluate the regenerative effects of EMD.

혼합형 유전자 알고리즘을 이용한 그래프 분할

김향태,양종현 광주대학교 산업기술연구소 2002 産業技術硏究 Vol.16 No.-

문제의 복잡도가 매우 큰 경우에는 순수한 유전자 알고리즘으로는 한정된 시간과 비용으로 만족할만한 품질의 해를 얻기에는 많은 어려움이 따른다. 또한, 유전자 알고리즘이 지역 최적점 근처에서 미세 조정 기능이 약하다는 것과 밀접한 관계가 있다. 본 논문에서는 미세 조정을 위해 지역 최적화 알고리즘을 유전자 알고리즘과 결합한 혼합형 유전자 알고리즘(Hybrid Genetic Algorithm; HGA)을 제한한다.

일부 장애인 복지관 전문직 종사자들의 직무 만족도에 영향을 미치는 요인

이태용,이향숙 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

This study was performed to increase the efficiency of running a rehabilitation center for the disabled and to maximize the job satisfaction of professional employees working at the center. The Price-Mueller Model was used to determine factors relating to the degree of employee satisfaction in the workplace. Factors were analyzed after classifying the degree of work and workplace satisfaction. A total of 121 people were included in the model. Comparisons were made of the degree of work satisfaction according to the characteristics of the population. Men. older workers with a 3∼6 year work duration. 3rd level employees. and married people scored higher in the degree of job satisfaction. Multiple regression analysis revealed that the explanatory variables having the greatest effect were promotional opportunity. compensation, variety of work. and workload. Psychological factors influencing job satisfaction were met expectations and positive affectivity. Demographic factors influencing job satisfaction were sex and marital status. Efforts to improve employee satisfaction in work performed, increase the variety of work. streamline job procedures. reduce workload. expand promotion opportunities, and improve compensation should be made in order to improve employee job performance.

산소 분위기하에서 Mg(OH)₂의 열분해 반응에 관한 연구(Ⅰ)

최원형,최태운 경성대학교 1985 부산수산대학 논문집 Vol.6 No.2

유전자 알고리즘을 이용한 타원 검출

김향태,박찬란,이웅기 조선대학교 통계연구소 1999 統計硏究所論文誌 Vol.1 No.1

본 논문은 농도화상에서 타원을 검출할 수 있는 알고리즘을 새롭게 제안한다. 알고리즘은 먼저 초기 화상에서 윤곽선을 검출한 후 윤곽선에서 타원을 만들 수 있는 가능한 후보를 선별해 낸다. 제안된 알고리즘에서 타원이란 세 점을 이용해서 윤곽선을 정의한다. 뿐만 아니라 유전자 알고리즘을 이용해서 화상에 가장 적합도가 높은 세 점의 윤곽선을 찾는 알고리즘을 제안한다. 또한 초기 화상을 사용해서 제안된 알고리즘의 성능을 평가한다. We present a new algorithm to detect ellipses in an intensity image. The algorithm first extracts line support regions from the original image. Next, candidates for elliptic arcs are selected from these line support regions. In the proposed algorithm, each ellipse is defined by triplet of line support regions, And, using a genetic algorithm, the proposed algorithm searches for triplets of line support regions that have highest fitness to the image. By experiments using original images, we estimate the performance of the proposed algorithm.

주물공장 근로자에서 발생한 국한성 석면폐증 1예

김태우,고동희,김민기,유승원,류향우,한정희,정순희 大韓産業醫學會 2009 대한직업환경의학회지 Vol.21 No.2

배경: 주물공장 근로자에서 발생한 석면폐증의 작업 관련성을 평가하고 그 증례를 보고하고자 한다. 증례: 30년간 주물공장에서 근무한 환자로 인후통, 기침, 노란 가래가 있어 검사한 결과 결핵이 의심되어 치료 하였으며, 치료 중 석면폐증으로 진단되었다. 작업 관련성 평가를 위해 실시한 폐 조직의 조직학적 검사에서 1 cm^(2)당 3개의 석면소체가 발견되었고, 투과전자현미경으로 분석한 석면 함유량은 23.26x10^(6) fibers/g이었다. 결론: 작업환경조사, 폐 조직의 석면 분석 등을 통해 작업 관련성이 높다고 판단하였다. Background: Foundry workers are known to be exposed to silica and have an increased risk of Silicosis. There are also reports that state these foundry workers were associated with asbestos-related change in the X-ray results of the lungs. This report discusses a case of localized asbestosis developed in a foundry worker who worked in 12 Korean foundries. Case report: A 49-year-o1d man who worked at molding and melting for 30 years, Presented with sore throat, cough and yellow sputum for 1 month. From physical and clinical examination, Pulmonary tuberculosis was highly suspicious; therefore, he was medicated for 6 months. After tuberculosis medication, the radiological finding was reactivation of tuberculosis, and an asbestos body was detected at a trans-bronchial lung biopsy. During an operation, operators found multiple palpable masses and bullae 10calized in the right upper lobe (RUL) and performed right upper lobectomy and right middle lobe wedge resection. Using hematoxylin-eosin stain and iron stain, we could detect asbestos bodies by light microscopy. We analyzed the asbestos fiber burden in dry lung tissue by transmission electron microscopy with energy dispersive X-ray spectrometer (TEM-EDX). The fiber type was chrysotile and the fiber burden was 23.26 x 10^(6) fiber/g dry lung. Discussion: This case study of a foundry worker with localized asbestosis is uncommon in Korea. We found an occupational relationship between the foundry worker and localized asbestosis through various investigative techniques such as measurements taken at his working environment, clinical, radiological and pathological examination of the foundry worker and mineralogical examination of the asbestos fiber.

다층 BTC에 대한 유전자 알고리즘 설계

김향태,이웅기 조선대학교 통계연구소 2000 統計硏究所論文誌 Vol.2 No.1

본 논문에서는 다층 BTC부호화의 설계에 대한 새로운 스키마를 제안한다. 최적의 양자화는 상세한 탐색으로 양자화 초기 값을 선택함으로써 얻을 수 있다. 그러나, 이것은 거대한 양의 계산결과를 요구하고, 또한 다층 BTC에 대한 상세한 탐색을 고려했을 때 비현실적이다. 원래의 이미지와 재구성된 이미지 사이의 AMSE(average mean square error)가 최소이기 위한 더 좋은 초기값을 유지하기 위해서 유전자 알고리즘을 적용한다. 상세한 탐색으로 제안된 방법의 결과치를 비교하면 전자의 방법이 대부분 후자의 경우에서 요구된 것보다 훨씬 적은 계산량으로 적절한 양자화를 달성할 수 있다.