방과 후 감각통합프로그램(감각통합치료)이 학교에서의 기능적 과제 수행에 미치는 효과

박지훈,이은정,노종수,이향숙,차정진 대한감각통합치료학회 2010 대한감각통합치료학회지 Vol.8 No.1

Objective : This study is designed to identify effect of a sensory integration(SI) program provided to elementary school students as an after-school activity. The study is looking at both occupational performance components and school-task performance which is an area of occupational performance. Methods : SI program specially designed as an after-school activity was provided to three boys who are first- or second grade students of Y elementary school in Dae-Jeon city. The SI intervention was organized with 25 sessions and carried out for two months. One group pretest-posttest design was used to evaluate the effectiveness of the SI program. Measurements used are Short Sensory Profile(SSP), K-DTVP-2, and BOTMP for occupational performance components, and School Function Assessment for functional schooltask performance. Results : It is found that posttest scores were enhanced in all assessments SSP; BOTMP; K-DTVP-2; and SFA. Conclusion : Results of this study simply propose that sensory integration program designed as after-school activity may have positive effects on not only occupational performance components but also on school-task performance of elementary school student. Since sample size is too small, however, there is limitation to find statistical significance. Further researches testing large number of subjects are required to boost the finding of this study. 목적 : 본 연구는 학교 방과 후 활동으로 감각통합치료를 제공하였을 때 작업수행요소와 더불어 작업수행영역인 학교에서의 기능적 과제수행에 미치는 영향을 알아보기 위하여 실시하였다. 연구 방법 : 실험은 대전 Y초등학교에 재학 중인 1-2학년 아동 3명을 대상으로 방과 후 활동 시간에 감각통합치료를 제공하였으며, 중재는 2010년 5월과 6월에 걸쳐 총 25회를 제공하였다. 감각통합치료효과를 알아보기 위해 단일집단 사전-사후 설계(one group pretest-posttest design)를 사용하였고, 작업수행요소에서의 변화를 알아보기 위하여 단축감각프로파일(SSP), 한국판 시지각 발달검사(K-DTVP-2), Bruininks-Oseretsky Test of Motor Proficiency 1(BOTMP)를 사용하였으며, 작업수행영역에서의 변화를 알아보기 위하여 학교에서의 기능적과제 수행능력에 대한 평가(School Function Assessment)를 사용하였다. 결과 : 방과 후 감각통합프로그램(감각통합치료)을 적용한 결과 대상아동들은 작업수행요소인 단축감각력(SSP), BOTMP, 한국판 시지각 발달검사(K-DTVP-2)의 수치상 향상을 보였으며, 작업수행영역인 학교에서의 기능적 과제 수행(SFA)의 점수에서도 향상을 보였다. 결론 : 본 연구를 통해 방과 후 감각통합프로그램(감각통합치료)이 작업수행요소와 학교에서의 기능적 과제수행에 긍정적인 영향을 미친다는 것을 보여주었지만, 대상의 수가 적어 통계적 유의성을 찾는 데는 한계가 있었다. 따라서 향후 연구에서는 대상자의 수를 고려한 연구들이 필요할 것으로 사료된다.

새로운 무기 응집제 개발에 따른 특성

최성우,우성훈,윤철종,곽명화,서향미,박승조 동아대학교 환경문제연구소 2000 硏究報告 Vol.23 No.1

This study has carried out the coagulation tests for tannery wastewater including high-level suspended solids and organic matters to determine the optimum pH and coagulant dosage and to characterize several coagulants for coagulation. In case of optimum pH range test, we know that multi-coagulants are not only cost-effective but also applicable from acidic pH range to alkaline pH range widely, while single-coagulant are useful in limited pH range. Removal efficiency for using of the multi-coagulants appeared more efficient than that of single-coagulant. Especially, sulfates(alum-ferric sulfate : AFS & alum-magnesium sulfate : AMS) are more effective than chlorides (alum-ferric chloride : AFC & alum-magnesium chloride AMC). In comparison of residual turbidity related to settling time between alum and alum-ferric sulfate-magnesium sulfate(AFM), it took to 40 minutes using of alum but 5 minutes using of alum-ferric sulfate-magnesium sulfate(AFM) until constant residual turbidity are reached.

자발성 기흉을 동반한 폐림프관평활근종증 1예

안용환,정종훈,김소영,김휘정,김학렬,양세훈,최순호,문형배,조향정,정은택 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

경기도 지역 정신보건 사업의 추진배경과 정책결정과정

이충순,윤배중,이주훈,이종국,고영,이영문,최향순,김혜숙 용인정신의학연구소 1997 용인정신의학보 Vol.4 No.2

생쥐 대장 평활근 세포에서 내향 정류성 칼륨 전류의 특성 연구

이은주,김명,정명섭,조향훈,김기훈,하현철,김준수,최석,전제열 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.2

Objectives: K^(+) channels play an important role in regulating cellular excitability. The aim of this study was to know whether or not inward rectifier K^(+) channel exists in colonic smooth muscle cells. Methods: Mouse colonic smooth muscle cells were isolated using collagenase, and then we recorded their membrane currents using a whole-cell patch clamp technique. Results: With 90 mM K^(+) in bath, hyperpolarization-induced inward currents from -120 mV to 20 mV with 400 ms duration at a holding potential of -10 mV showed rapid activation, inactivation and inward rectification. The inactivation showed single exponential time course. Reduction of external K^(+) to 60 mM decreased the amplitudes of the currents in whole test voltage range and shifted the reversal potential to more negative potential. The inactivation process and peak currents of hyperpolarization-induced inward currents were not affected by removing external Na^(+). External Ba^(+) blocked hyperpolarization-induced inward currents by dose-dependent manner and pure Ba^(+)-sensitive currents showed strong inward rectification. Cs^(+) also suppressed hyper- polarization-induced inward currents. Ba^(+) and Cs^(+)-induced inhibitiOn of hyperpolarization-induced inward currents was voltage-dependent, and the extent of inhibition increasing with membrane hyperpolarization. Conclusions: These results suggest that inward rectifier KU channels may exist in proximal colonic smooth muscle and may play an important role in regulating membrane potential.

안구적출에 따른 위둔덕의 Calbindin D-28k과 c-fos의 변화에 관한 연구

김명,김기훈,김주영,하현철,안명수,김장민,조향훈,정명섭,장인엽 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Changes of Calbindin D-28k- and c-fos-immunoreactivities in the superior collicuclus after Eye Enucleation. Objective and methods: Calcium-binding proteins (CBPs) play an important role in the protection, differentiation and reorganization of the central nervous system. The effects of neonatal retinal deafferentation on a CBPs, calbindin D-28k were examined immunohistochemically in the superficial layer of the rat superior colliculus. Also early gene familly c-fos was examined to evaluate the neuronal characteristics in the superior colliculus after monocular enucleation. Results: On the experimental side of superior colliculus, the number of calbindin D-28k-immunoreactive (IR) cells was reduced (77.4% compared to control), but not fibers. Appearance of c-fos-like immunoreactivity was represented much more in the ipsilateral superior colliculus than contralateral side within 24h after eye enucleation. Conclusion: These results suggest that the changes of retinotectal projection may alter the expressional pattern of calbindin D-28k and c-fos expression.

Boric oxide deposition on carbon nanofibers for oxidation resistance.

Chae, Hyang Hoon,Kim, Bo-Hye,Yang, Kap Seung,Woo, Hee-Gweon American Scientific Publishers 2013 Journal of Nanoscience and Nanotechnology Vol.13 No.8

<P>The boric oxide deposition was performed to improve the oxidation resistivity of carbon nanofiber (CNF) from electrospinning at elevated temperatures. The stabilized electrospun polyacrylonitrile (PAN) nanofibers were coated with boric oxide, followed by heat treatment up to 1000, 1200, and 1400 degrees C in an inert nitrogen atmosphere. The relative oxidation resistance of boric oxide-coated CNFs showed oxidation resistive property, which was determined by weight loss after running a thermogravimetric analyzer (TGA) under air flow. The data were used for the calculations of activation energies through Arrhenius plot. The oxidation resistance of the boric oxide-coated CNFs was depended on the heat treatment temperature, the higher the temperature more resistive to oxidation. The boric oxide-coated CNFs showed extended oxidation resistivity as remaining 40-83% (w) of the original weight at the high temperature 1000 degrees C under air.</P>

체외수정시술을 위한 과배란 유도 시 유전자 재조합에 의하여 생산된 사람융모생식샘자극호르몬제의 임상적 효용성에 관한 연구

이향아 ( Hyang Ah Lee ),김정훈 ( Chung Hoon Kim ),구윤희 ( Yun Hee Koo ),서미원 ( Mi Won Seo ),김성훈 ( Sung Hoon Kim ),채희동 ( Hee Dong Chae ),강병문 ( Byung Moon Kang ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.4

목적: 보조 생식술을 위한 과배란 유도의 과정 중 최종 난포의 성숙 유도를 위하여, 임신한 여성의 뇨 중에서 추출된 사람 융모생식샘자극호르몬제재의 투여는 필수적인 과정이다. 그러나 뇨 추출물 과정에서 생기는 정제 과정의 불확실성, 소변의 정도 관리의 어려움, 항원 항체 반응의 출현, 동일 단위당의 예측 불가능한 효능 등이 문제점으로 제기 되고 있다. 본 연구에서는 재조합법으로 생성된 사람융모생식샘자극호르몬제재의 최종 난포 성숙과 관련된 임상적 효용성을 알아보고자 하였다. 연구방법: 2005년 1월부터 9월까지 서울 아산병원 불임 클리닉에서 체외 수정술을 시행 받은 환자 84명을 대상으로 전향적으로 연구되었다. 난자 채취 36시간 전에 42명에게는 재조합 사람융모생식샘자극호르몬 250 ug투여 되었으며 대조군에는 요 추출 사람융모생식샘자극호르몬 10,000 IU가 투여되었다. 난자 채취일에 약물의 국소적 부작용이 조사되었고 3일 후에 배아 이식하였다. 또한 두 군의 채취된 난자의 수, 수정된 난자의 수와 질, 배아의 질, 임신률을 비교하였다. 결과: 성선 자극 호르몬 투여 후 5일째의 혈중 사람융모생식샘자극호르몬과 프로제스테론 농도는 재조합 사람융모생식샘자극호르몬을 투여받은 군에서 유의하게 높았다 (p<0.01, p<0.05). 그 외의 채취된 난자의 질과 개수, 배아의 질, 임신률은 차이를 보이지 않았다. 또한 동통, 가려움, 피하 출혈 등의 약물 투여 부위의 국소적 부작용은 재조합 사람융모생식샘자극호르몬을 투여받은 군에서 의미 있게 낮은 빈도를 나타냈다 (p<0.01, p<0.01 and p<0.05). 결론: 체외 수정술을 위한 과배란 유도 환자 군에서 재조합 사람융모생식샘자극호르몬의 투여는 황체기의 황체호르몬의 농도를 상승시켰으며 국소적인 부작용은 요추출 제재 보다 의미 있게 낮았다. Object: Human chorionic gonadotropin (hCG) is used to induce final follicular maturation in women undergoing controlled ovarian hyperstimulation (COH). Urinary preparations are associated with a number of disadvantages including an uncontrolled source, batch-to-batch variability and lack of purity. We performed this study to compare the efficacy of recombinant hCG and urinary hCG for induction of final follicular maturation in women undergoing IVF-ET. Methods: Prospective trial was performed on a total of 84 IVF cycles carried out in 84 infertile women with tubal and peritoneal factor. Patients were randomized 1:1 to 250 ug of recombinant hCG subcutaneous injection or 10,000 IU of urinary hCG intramuscular injection after completing recombinant human follicle stimulating hormone (FSH) stimulation. Oocyte pickup was scheduled 36 hours after hCG administration and embryos were transferred 3 days after oocyte pickup. We measured the efficacy points including the number of retrieved and fertilized oocytes, quality of oocytes and embryos, and clinical pregnancy rate. Results: Serum progesterone and hCG level on post-hCG day 5 were significantly higher in the recombinant hCG group (p<0.01, p<0.05). There were no significant differences in outcome including the number of retrieved oocytes, quality of oocytes and embryos, clinical pregnancy rate between the two preparations. The incidence of injection-site reactions such as pain, itching, and bruising were significantly lower in the recombinant hCG group (p<0.01, p<0.01 and p<0.05). Conclusions: For triggering ovulation, recombinant hCG seems to have significant advantages compared with urinary hCG in terms of luteal progesterone and local tolerance.

한국인 자궁내막증 환자에서 혈관내피세포 성장인자 유전자 촉진자 C(-634)G 부위의 다형성 분석

이향아 ( Hyang Ah Lee ),전균호 ( Gyun Ho Jeon ),최정원 ( Jeong Won Choi ),김성훈 ( Sung Hoon Kim ),채희동 ( Hee Dong Chae ),김정훈 ( Chung Hoon Kim ),강병문 ( Byung Moon Kang ),최영민 ( Young Min Choi ) 대한산부인과학회 2005 Obstetrics & Gynecology Science Vol.48 No.1

Association of programmed cell death 1(PD-1) with susceptibility to Ankylosing Spondylitis in Korean population

( Sang Hoon Lee ),( Yeon Ah Lee ),( Doo Hyun Woo ),( Hyang Ie Lee ),( Seung Jae Hong ),( Eun Kyung Park ),( Mi Hyun Ryu ),( Young Hoon Kim ),( Kyoung Soo Kim ),( Hyung In Yang ) 대한내과학회 2005 대한내과학회 추계학술대회 Vol.69 No.10