Hong JeongHa's Tianyuanshu and Zhengcheng Kaifangfa

홍성사,홍영희,김영욱,Hong, Sung Sa,Hong, Young Hee,Kim, Young Wook The Korean Society for History of Mathematics 2014 Journal for history of mathematics Vol.27 No.3

Tianyuanshu and Zengcheng Kaifangfa introduced in the Song-Yuan dynasties and their contribution to the theory of equations are one of the most important achievements in the history of Chinese mathematics. Furthermore, they became the most fundamental subject in the history of East Asian mathematics as well. The operations, or the mathematical structure of polynomials have been overlooked by traditional mathematics books. Investigation of GuIlJib (九一集) of Joseon mathematician Hong JeongHa reveals that Hong's approach to polynomials is highly structural. For the expansion of $\prod_{k=11}^{n}(x+a_k)$, Hong invented a new method which we name Hong JeongHa's synthetic expansion. Using this, he reveals that the processes in Zhengcheng Kaifangfa is not synthetic division but synthetic expansion.

홍씨 앞방각측정법의 임상적 유용성

강신희,박기호,홍철,김동명,Shin Hee Kang,M,D,Ki Ho Park,M,D,Chul Hong,M,D,Dong Myoung Kim,M,D 대한안과학회 2007 대한안과학회지 Vol.48 No.3

Purpose: To compare the Hong`s grading method, utilized for slit-lamp grading of the mid-peripheral angle, with other conventional grading methods. Actual angle was measured by ultrasound biomicroscopy (UBM) for comparison. Methods: Fifteen eyes with narrow angles and eighteen eyes with wide angles were studied. The average age of thirty-three subjects was 46.8±19.2, and the male to female ratio was 1:3.7. The mid-peripheral angle was graded by Hong`s, van Herick`s and Spaeth`s grading system. The actual anterior chamber angle was evaluated by UBM and the correlation between each grading system and actual angle was investigated. Results: The results from the Hong`s grading (r=0.802, R2=0.643, p<0.01), Spaeth`s grading (r=0.728, R2=0.530, p<0.01) and van Herick`s grading (r=0.618, R2=0.382, p<0.01) methods correlated significantly with the actual angles. Conclusions: The Hong`s grading method was an easy and effective tool to evaluate anterior chamber angle. In addition, the results of the Hong`s grading method were closer to the actual angle than the other methods.

Adiponectin Attenuates the Inflammation in Atopic Dermatitis-Like Reconstructed Human Epidermis

( Hee-seok Seo ),( Ki Hyun Seong ),( Chang-deok Kim ),( Seong Jun Seo ),( Byung Cheol Park ),( Myung Hwa Kim ),( Seung-phil Hong ) 대한피부과학회 2019 Annals of Dermatology Vol.31 No.2

Background: Atopic dermatitis (AD) is a chronic disorder, with a vicious cycle of repetitive inflammation and deterioration of the epidermal barrier function. Adiponectin, an adipokine, has anti-inflammatory effects on various metabolic and inflammatory disorders. Recently, its level was found to be reduced in serum and tissue samples from AD patients. Objective: We aimed to investigate the effects of adiponectin on epidermal inflammation and barrier structures in AD skin. Methods: A three-dimensional in vitro epidermal equivalent model mimicking AD was obtained by adding an inflammatory substance cocktail to normal human epidermal equivalents (HEEs). The expression of epidermal differentiation markers, primary inflammatory mediators, and lipid biosynthetic enzymes was compared between adiponectintreated AD-HEEs, untreated control AD-HEEs, and normal HEEs. Results: Adiponectin co-treatment 1) inhibited the increase in mRNA expression of major inflammatory mediators (carbonic anhydrase II, neuron-specific NEL-like protein 2, thymic stromal lymphopoietin, interleukin-8, tumor necrosis factor-alpha, and human beta-defensin-2) from keratinocytes in AD-inflammatory HEEs, 2) enhanced the expression of lipid biosynthetic enzymes (fatty acid synthase, HMG CoA reductase, and serine-palmitoyl transferase), and 3) promoted the expression of differentiation factors, especially filaggrin. We also found that the expression of adiponectin receptor-1 and -2 decreased in the epidermis of chronic AD lesion. Conclusion: Activation of the adiponectin pathway is expected to enhance epidermal differentiation and barrier function as well as attenuate inflammatory response to AD as a therapeutic approach. (Ann Dermatol 31(2) 186∼195, 2019)

Study on the Weldability and Mechanical Characteristics of Dissimilar Materials (Al5052-DP590) by TIG Assisted Hybrid Friction Stir Welding

Hee‑Seon Bang,Seong Min Hong,Atanu Das,Han‑Sur Bang 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.5

Hybrid friction stir welding, adopting an external pre-heat source in front of the friction stir welding (FSW) tool, is knownas a way of overcoming the disadvantages of conventional FSW; lack of plastic flow and excessive tool wear. In joining ofaluminum alloy to steel, presence of intermetallics (IMC) is essential, but its excessive growth can degrade the joint qualityby its brittleness. In this study, joining of 2.5 mm thick Al5052 aluminum alloy and 1.4 mm thick DP590 high strength steelhas been carried out by FSW and TIG assisted hybrid friction stir welding (HFSW) through experiments and numericalanalysis. Joints characteristics of two process was compared to optimize the process parameters. A 3-D model was developedto estimate the thermal elastic–plastic characteristics of the joints. It was confirmed that the joint efficiency of HFSW jointshas been improved to 84% than that of FSW (74%). 2.74 μm thickness of IMC layer was formed in HFSW joints and satisfiedthe permissible thickness (under 10 μm). The maximum residual stress (σzz) in welding direction was slightly higherat the HFSW joints than at the FSW joints. The overall results from experiment and simulation confirmed that HFSW is aneffective way of joining Al5052 to DP590.

경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염

홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.

Studies on the Activation Mechanism of c-src Protein Tyrosine Kinase by Ginsenoside-Rg1

Hong, Hee Youn,Yoo, Gyurng Soo,Choi, Jung Kap 전남대학교 약품개발연구소 1998 약품개발연구지 Vol.7 No.1

We have studied an activation mechanism of pp60^(c-src) protein tyrosine kinase (PTK) by ginsenoside-Rg₁ (G-Rg₁) in NIH(pMcsrc/foc)B c-src overexpressor cells. It was previously reported that G-Rg₁ stimulated the activation of c-src kinase at 20 μM with a 18 hr-incubation, increasing the activity by 2-4-fold over that of untreated control, and this effect was blocked by treatments of inhibitors of either protein synthesis (cycloheximide) or RNA synthesis (actinomycin D) (Hong. H.Y. et al. Arch. Pharm. Res. 16, 114 (1993)). However, an amount of c-src protein itself in wild-type cells was not changed by G-Rg₁. When the cells mutated at one or two tyrosine residue(s) (Y416/527) that are important sites to regulate the kinase activity were treated with G-Rg₁, increases both in the activity of c-src kinase and in the expression of the protein were not observed. In addition, removal of extracellular calcium ion by EGTA or inhibition of PKC by H-7 canceled the G-Rg₁-induced activation of the kinase. Although the activation was little affected by G-Rg₁ with a calcium ionophore A23187, it was synergistically stimulated by treatment of G-Rg₁ and PMA, a PKC activator. Taken together, these results suggest that the activation of c-src kinase by G-Rg₁ is caused by an increase in the specific activity of the kinase, but not in amount of it, and is involved with both cellular calcium ion and PKC. Further the increase in the specific activity of c-src kinase may result from altered phosphorylation at tyr-416 and -527.

압착방법별 포도 착즙액의 품질특성

최희돈,김성수,김경탁,홍희도,김상희 한국식품영양학회 2002 韓國食品營養學會誌 Vol.15 No.3

캠벨과 거봉을 이용하여 여러 가지 압착방법에 따른 착즙액의 이화학적 및 관능적 특성을 조사하였다. 수율의 경우 캠벨, 거봉이 동일하게 냉압처리보다는 온압처리가, 온압처리에서도 낮은 온도보다는 높은 온도에서 수율이 높게 나타났으며, 또 온압 · 펙틴분해 병행처리가 각각 83.5% , 87.3%로 가장 높은 수율을 나타내었다. 또한 당도와 아미노테 질소도 열처리온도의 상승 및 압착방법의 병행에 의해 감소하는 것으로 나타났다. 적정산도는 캠밸과 거봉이 압착방법에 따라 각각 0.86 ~ 1.00%, 0.60 ~ 0.69%로 거봉에 비해 캠벨의 산도가 높았으며, 열처리온도가 산도 증감에 더 큰 영향을 미치는 것으로 나타났다. 그리고 압착방법에 따른 착즙액에 대한 관능검사 결과 열처리 온도의 상승 및 착즙액에 대한 관능검사 결과 열처리온도의 상승 및 압착방법의 병행에 의해 떫은 맛과 산맛의 강도가 강하여지고 이들 처리구의 기호도가 높은 것으로 나타났다. The physicochemical and sensory properties of Campbell Early and Gerbong juices prepared by various pressing methods were studied. The yields of these juices by mixed method were 83.5% and 87.5%, the highest value of various pressing methods. And soluble solids and amino nitrogens of them decreased as heating temperature increased and was lowest when mixed method was performed. Titratable acidities of Campbell Early juice was 0.86 ~ 1.00%, higher than that of Gerbong juice, 0.60 ~ 0.69%. Also the strength of astringent taste and sour taste of Campbell Early and Gerbong juice increased as heating temperature increased, and increased strength of these tastes gave good sensory evaluation to grape juices.

TLD 방사선 센서용 판독장치의 제작

우홍,강희동,최희동,이상윤,도시홍,김도성 경북대학교 센서기술연구소 1992 센서技術學術大會論文集 Vol.3 No.1

Chosun Mathematics in the early 18th century

홍성사,홍영희,Hong, Sung-Sa,Hong, Young-Hee The Korean Society for History of Mathematics 2012 Journal for history of mathematics Vol.25 No.2

1592년과 1636년 양대 전란으로 전통적인 조선 산학의 결과는 거의 소멸되어, 17세기 중엽 조선 산학은 새로 시작할 수밖에 없었다. 조선은 같은 시기에 청으로 부터 도입된 시헌력(時憲曆, 1645)을 이해하기 위하여 서양수학에 관련된 자료를 수입하기 시작하였다. 한편 전통 산학을 위하여 김시진(金始振, 1618-1667)은 산학계몽(算學啓蒙, 1299)을 중간(重刊)하였다. 이들의 영향으로 이루어진 조태구(趙泰耉, 1660-1723)의 주서관견(籌書管見)과 홍정하(洪正夏, 1684-?)의 구일집(九一集)을 함께 조사하여 이들이 조선 산학의 발전에 새로운 전기를 마련한 것을 보인다. After disastrous foreign invasions in 1592 and 1636, Chosun lost most of the traditional mathematical works and needed to revive its mathematics. The new calendar system, ShiXianLi(時憲曆, 1645), was brought into Chosun in the same year. In order to understand the system, Chosun imported books related to western mathematics. For the traditional mathematics, Kim Si Jin(金始振, 1618-1667) republished SuanXue QiMeng(算學啓蒙, 1299) in 1660. We discuss the works by two great mathematicians of early 18th century, Cho Tae Gu(趙泰耉, 1660-1723) and Hong Jung Ha(洪正夏, 1684-?) and then conclude that Cho's JuSeoGwanGyun(籌 書管見) and Hong's GuIlJib(九一集) became a real breakthrough for the second half of the history of Chosun mathematics.

야쿠트어 폐쇄자음 연구-러시아어 차용어휘 분석-

강덕수 ( Duck Soo Kang ),김지선 ( Jee Sun Kim ),홍준희 ( Jun Hee Hong ) 한국외국어대학교 언어연구소 2007 언어와 언어학 Vol.0 No.39

Duck-soo Kang.Jee-sun Kim.Jun-hee Hong. 2007. A Study of Obstruents in Yakut through Analysis of Borrowed Words from Russian. Language and Linguistics 39, 1-16. One of the most important constraints in Yakut is connected with syllabic structure. Its syllabic structure is based on CV. So the constraint of "NoGeminates" is strictly applied. And the harmony between features is also considered important. Yakut has the strict constraint on the phonotactical relations. In Yakut a feature [constricted glottis] works more vigorously than [voiced]. This feature is combined with a feature [+back] or [+lab], making new constraints on the initial place: *#[+back, -CG], *# [+lab,+CG]. Finally, consonantal assimilation in obstruents of Yakut is dominated by 2 lows of constraints. VowelHarmony >> Ident-CV[pl] >> NCP >> *[+palatal]# >> Ident-IO; *#[+back, -cont][+back,-high] >> *#[+back,-CG], *# [+lab,+CG] >> [+cont] >> NoGem >> Ident-IO >> *[+voiced]#