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Molecular phylogenetic study of Arca boucardi using metallothionein gene
Jie Eun Park,Se Won Kang,Hee-Ju Hwang,Dae Kwon Song,Min Kyu Sang,Hye Rin Min,Jong Min Chung,Hee Cheol Ha,Hyun Jun Lee,Chan Eui Hong,Hong Seog Park,Yeon Soo Han,Jun Sang Lee,Yong Seok Lee 한국수산과학회 양식분과 2016 한국수산과학회 양식분과 학술대회 Vol.2016 No.10
Hong, Eun-Hee,Song, Jie-Young,Lee, Su-Jae,Park, In-Chul,Um, Hong-Duck,Park, Jong Kuk,Lee, Kee-Ho,Nam, Seon Young,Hwang, Sang-Gu unknown 2014 IUBMB LIFE Vol.66 No.2
<P>Although low-dose radiation (LDR) regulates a wide range of biological processes, limited information is available on the effects of LDR on the chondrocyte phenotype. Here, we found that LDR, at doses of 0.5–2 centiGray (cGy), inhibited interleukin (IL)-1β-induced chondrocyte destruction without causing side effects, such as cell death and senescence. IL-1β treatment induced an increase in the expression of α-, β-, and γ-catenin proteins in chondrocytes via Akt signaling, thereby promoting dedifferentiation through catenin-dependent suppression of Sox-9 transcription factor expression and induction of inflammation through activation of the NF-κB pathway. Notably, LDR blocked cartilage disorders by inhibiting IL-1β-induced catenin signaling and subsequent catenin-dependent suppression of the Sox-9 pathway and activation of the NF-κB pathway, without directly altering catenin expression. LDR also inhibited chondrocyte destruction through the catenin pathway induced by epidermal growth factor, phorbol 12-myristate 13-acetate, and retinoic acid. Collectively, these results identify the molecular mechanisms by which LDR suppresses pathophysiological processes and establish LDR as a potentially valuable therapeutic tool for patients with cytokine- or soluble factors-mediated cartilage disorders.</P>
New Issues on Legal Sanction in Korea, China and Japan Position of Criminal Law in Risk Society
( Hong Jie Tian ) 아세아여성법학회 2013 아세아여성법학 Vol.16 No.-
Risk society is not only a cognitive theory at the cultural level, but also features on its reflection significance at the political level and its reconfiguration connotation at the institutional level. Thus, any interpretation or analysis made from any single aspect for the risk society is unavoidably unilateral and single-track. The features of the risk society are increasingly prominent in modem society, which indicates the insufficiencies of the central governance capacity of the State and the failure of rigid governance mode created by laws. Therefore, facing the challenges of the risk society, no matter the adjustments on the governance structure or the society and reforms on the governance mode of the State, are continuously in pursuit of rational limitation of powers of the State, scientific configuration of multi-governance mechanism and firm defending for position of restraint of criminal law, rather than reinforcement of the power of the State and active expansion of function of criminal law.
Molecular phylogenetic study of Arca boucardi using metallothionein gene
Jie Eun Park,Se Won Kang,Hee-Ju Hwang,Dae Kwon Song,Min Kyu Sang,Hye Rin Min,Jong Min Chung,Hee Cheol Ha,Hyun Jun Lee,Chan Eui Hong,Hong Seog Park,Yeon Soo Han,Jun Sang Lee,Yong Seok Lee 한국수산해양기술학회(구 한국어업기술학회) 2016 한국수산해양기술학회 학술발표대회 Vol.2016 No.10
Deuterium Clusters Fusion Induced by the Intense Femtosecond Laser Pulse
Hong-Jie, Liu,Zhi-Jian, Zheng,Yu-Qiu, Gu,Bao-Han, Zhang,Yong-Joo, Rhee,Sung-Mo, Nam,Jae-Min, Han,Yong-Woo, Rhee,Kwon-Hae, Yea,Jia-Bin, Chen,Hong-Bin, Wang,Chun-Ye, Jiao,Ying-Ling, He,Tian-Shu, Wen,Xia ALLERTON PRESS INC 2007 CHINESE PHYSICS LETTERS Vol.24 No.2
<P>Neutrons (2.45 MeV) from deuterium cluster fusion induced by the intense femtosecond (30 fs) laser pulse are experimentally demonstrated. The average neutron yield 10<SUP>3</SUP> per shot is obtained. It is found that the yield slightly increases with the increasing laser spot size. No neutron can be observed when the laser intensity I < 4.3×10<SUP>15</SUP> W/cm<SUP>2</SUP>.</P>
A Secret Sharing Scheme Based on AES
Jie Cui,Lei Chen,Yiming Zhang,Zhiqiang Xie,Hong Zhong 보안공학연구지원센터 2014 International Journal of Security and Its Applicat Vol.8 No.6
In order to solve the key setting difficulty and the key security problem in the file encryption, key distributed storage technology may be a proper choice to help improve the safety of the key. In the paper, a novel secret sharing scheme is proposed by AES encryption algorithm for file confidentiality, dynamic key generation mechanism to generate keys, multi-secret-sharing ideas on key pre-treatment, using Shamir threshold scheme for secret dispersed storage. Finally, a few tests are carried out and the test results suggest that the efficiency of the whole scheme is good.
Hong-Guan Xie,Yong-Gang Bao,Li-ping Bai,Jun-Jie Shan,Rong Jiang,Yang Zhang,Lian-Hong Guo,Ren Zhang,Yuan Li 한국미생물학회 2009 The journal of microbiology Vol.47 No.2
Streptomyces sp. 139 generates a novel exopolysaccharide (EPS) designated as Ebosin, which exerts an antagonistic effect on IL-1R in vitro and anti-rheumatic arthritis activity in vivo. A ste gene cluster for Ebosin biosynthesis consisting of 27 ORFs was previously identified in our laboratory. In this paper, ste16 was expressed in Escherichia coli BL21 and the recombinant protein was purified, which has the ability to catalyze the transfer of the methyl group from S-adenosylmethionine (AdoMet) to dTDP-4-keto-6-deoxy-D-glucos, which was thus identified as a methyltransferase. In order to determine the function of ste16 in Ebosin biosynthesis, the gene was disrupted with a double crossover via homologous recombination. The monosaccharide composition of EPS-m generated by the mutant strain Streptomyces sp. 139 (ste16-) was found to differ from that of Ebosin. The IL-1R antagonist activity of EPS-m was markedly lower than that of Ebosin. These experimental results have shown that the ste16 gene codes for a methyltransferase which is involved in Ebosin biosynthesis.